Stockwinners Market Radar for April 18, 2023 - Earnings, Upgrades downgrades, option trades, Best Stock Advisory Service

PANW

Hot Stocks

20:30 EDT Palo Alto Networks CEO sell $2.78M in common stock - In a regulatory filing, Palo Alto Networks disclosed that its CEO Nikesh Arora sold 13.8K shares of common stock on April 17th in a total transaction size of $2.78M.
DNA

Hot Stocks

20:29 EDT Cathie Wood's ARK Investment bought 602.6K shares of Ginkgo Bioworks today
RBLX

Hot Stocks

20:28 EDT Cathie Wood's ARK Investment bought 211.3K shares of Roblox today
NFLX

Hot Stocks

18:37 EDT Netflix says wants to have differentiated gaming experience - Says has 41 games on platform right now. Says "Oxenfree II" coming to Netflix Games later this year.
NFLX

Hot Stocks

18:35 EDT Netflix says 'Love is Blind' live reunion show drew 6.5M viewers
MKFG

Hot Stocks

18:32 EDT Markforged receives non-compliance letter from NYSE - Markforged Holding was notified on April 18 by the NYSE that the Company is not in compliance with Rule 802.01C of the NYSE's Listed Company Manual relating to the minimum average closing price of the Company's common stock required over a consecutive 30 trading-day period. The notice does not result in the immediate delisting of the Company's common stock from the NYSE. The Company intends to notify the NYSE within 10 business days of its intent to regain compliance with Rule 802.01C. The Company can regain compliance at any time within the six-month cure period if, on the last trading day of any calendar month during the cure period, the common stock has a closing share price of at least $1.00 and an average closing share price of at least $1.00 over the 30 trading-day period ending on the last trading day of that month. The Company fully intends to remain listed on the NYSE, and will consider the best available alternatives, including, but not limited to, a reverse stock split, subject to stockholder approval, if necessary to regain compliance. The Company's common stock will continue to be listed on the NYSE during the six-month cure period, subject to the Company's compliance with other NYSE continued listing requirements.
NFLX

Hot Stocks

18:30 EDT Netflix 'sorry' about live 'Love is Blind' show problems - Says film division "doing great." Says Netflix films that won awards and received critical acclaim also had high viewership numbers on the platforms. Says "sorry" about disappointing viewers during live "Love is Blind" show.
NFLX

Hot Stocks

18:24 EDT Netflix says looking for 'fair and equitable deal' to avoid WGA strike - Says respects writers and WGA. Says doesn't want WGA strike, says last strike was "devastating" for creators and industry. Says looking for fair and equitable deal to avoid WGA strike. Says content library can serve subscribers better than most rivals in event of a strike.
AEM

Hot Stocks

18:23 EDT Agnico Eagle Executive Chairman: We like our positioning - In an interview on CNBC's Mad Money, Sean Boyd said, "We've positioned the company to be the third largest gold producer. We think we're going to see higher gold prices." He noted there is significant M&A in the space because there aren't a lot of new gold mines. He doesn't think supply is going to increase as gold prices rise. The lead time from discovery to production is longer than ever, he added.
NFLX

Hot Stocks

18:09 EDT Netflix says rollout of paid sharing has gone well - Says countries with price cuts contribute less than 5% sales. Says price cuts not material to business any time soon. Says rollout of paid sharing has gone well. Says planning to roll out paid sharing in most countries in Q2. Says directionally consistent with what company saw in Latin America in terms of paid sharing. Comments taken from Q1 earnings conference call.
LUNR KBR

Hot Stocks

18:07 EDT Intuitive Machines and KBR joint venture awarded contract by NASA - Intuitive Machines (LUNR) announced NASA awarded Space & Technology Solutions, the DBA for Space Networks Solutions, a joint venture led by Intuitive Machines with KBR (KBR), a cost-plus-fixed-fee indefinite-delivery, indefinite-quantity contract meant to support work related to the Joint Polar Satellite System, NASA's Exploration and In-space Services. The single-award contract has a five-year base performance period and a maximum ordering value of $719M. The NASA OMES III contract's principal purpose is to support the NASA GSFC Engineering and Technology Directorate, or ETD. ETD is an end-to-end science mission operation that is instrumental in designing missions, building satellites and instruments, operating, and controlling spacecraft, and acquiring and distributing data to the worldwide science community.
ZUMZ

Hot Stocks

18:03 EDT Zumiez exec Brown sells 40,000 common shares - In a regulatory filing, Zumiez North America President Troy Brown disclosed the sale of 40,000 common shares of the company on April 17 at a price of $18.55 per share.
MRTN...

Hot Stocks

17:52 EDT Shares of Marten Transport fall over 6% after Q1 revenue misses estimates - Shares of temperature-sensitive truckload carrier Marten Transport (MRTN) are dropping over 6% in after-hours trading on Tuesday evening after reporting revenue of $298M for the first quarter from $287.3M for the first quarter of 2022. Analysts were expecting revenue 309.89M. The company beat analyst estimates by a penny on the bottom line with 28c against 27c consensus estimates. Executive Chairman Randolph L. Marten stated, "Our bright and determined people executing our unique business model produced solid operating results despite the impact of widespread severe winter weather and a freight market which has considerably softened from the exceptionally tight conditions during the first half of last year. The market has become unsustainable for the smaller carriers who comprise a significant portion of total capacity, and who are expected to continue the recent increased industry exit rate." "We believe that we are well-positioned to capitalize on profitable organic growth opportunities across our five distinct but complementary business platforms with our emphasis on premium service, data-driven operating efficiencies and cost controls - and, as a result, to expand the total capacity we provide transporting and distributing the essential food, beverages and other consumer goods to support at a fair price our diverse and growing customer base." Other publicly traded companies in the space include: Landstar System (LSTR), J.B. Hunt Transport (JBHT), Old Dominion Freight Line (ODFL),Knight-Swift Transportation (KNX) , and Covenant Logistics Group (CVLG).
ISRG

Hot Stocks

17:40 EDT Intuitive Surgical jumps 9% to $294.32 after Q1 results beat estimates
FULT

Hot Stocks

17:12 EDT Fulton Financial slips 4% to $12.60 after Q1 earnings miss
BANX

Hot Stocks

17:09 EDT ArrowMark Financial Corp. estimates NAV of $20.62 as of March 31 - ArrowMark Financial Corp. announced that BANX's estimated and unaudited Net Asset Value as of March 31, 2023, was $20.62. This estimated NAV is not a comprehensive statement of our financial condition or results for the month ended March 31, 2023.
AES

Hot Stocks

17:08 EDT AES Corp. announces pact to terminate PPA for coal-fired plant in Maryland - The AES Corporation announced an agreement to terminate the Power Purchase Agreement for its 205 MW Warrior Run coal-fired power plant in Maryland. The offtaker, Potomac Edison, a subsidiary of FirstEnergy Corp., agreed to terminate the PPA for a total consideration of $357M, subject to approval by the Maryland Public Service Commission. If approved, the early termination of the PPA is forecasted to save Potomac Edison's customers nearly $80M over the next seven years, and will help the State of Maryland achieve its decarbonization targets. "This agreement is another milestone in our journey toward decarbonization," said Andres Gluski, AES President and Chief Executive Officer. "Following the contract termination, we see interesting opportunities to repurpose the Warrior Run site for low carbon solutions that continue to serve local communities." Under the terms of the agreement, AES will continue to operate the Warrior Run plant through at least May 2024. AES will work with existing employees to manage a responsible transition. AES will maintain full operational control of the site following decommissioning.
GDYN

Hot Stocks

17:07 EDT Grid Dynamics acquires NextSphere Technologies, terms not disclosed - Grid Dynamics announced that it had acquired NextSphere Technologies-a full-service custom application development firm. With over 200 employees across US and India, Nextsphere Technologies will support Grid Dynamics' objectives of enhancing its technical offerings, expanding in global footprint, and increasing its client base. "The acquisition of NextSphere Technologies enhances our technical capabilities and expands our global footprint. With a proven track record of serving customers across the Healthcare, Fintech, and CPG/Manufacturing industries, Nextsphere Technologies' expertise will complement Grid Dynamics' offerings to existing and new customers. Additionally, the industries where Nextsphere Technologies has focused are key to Grid Dynamics' Gigacube strategy of diversifying and growing to a billion-dollar revenue company. With its headquarters in Tampa and delivery operations in India with Hyderabad and Chennai as the key centers, the acquisition strengthens our global delivery position in serving our clients", said Leonard Livschitz, CEO of Grid Dynamics.
CEI

Hot Stocks

17:06 EDT Camber Energy discloses communication from NYSE American - Camber Energy announced that on April 12, 2023 it received a letter from the NYSE American LLC advising the company is not in compliance with the NYSE American continued listing standards set forth in Sections 1003(a)(i), (ii) and (iii) of the NYSE American Company Guide given the reported stockholders' deficit as of December 31, 2022, and losses from continuing operations and/or net losses in its five most recent fiscal years then ended. The Notice has no immediate impact on the listing of the Company's shares of common stock, par value $0.001 per share, which will continue to be listed and traded on the NYSE American during the period mentioned below, subject to the Company's compliance with the other listing requirements of the NYSE American. The Common Stock will continue to trade under the symbol "CEI", but will have an added designation of ".BC" to indicate the status of the Common Stock as "below compliance". The notice does not affect the Company's ongoing business operations or its reporting requirements with the Securities and Exchange Commission
AMD...

Hot Stocks

17:06 EDT EU takes on US and Asia with EUR 43B chip subsidy plan - The European Commission said in part, earlier on Tuesday: "The Commission welcomes the political agreement reached between the European Parliament and the EU Member States on the European Chips Act, proposed by the Commission on 8 February 2022, including on the budget. Semiconductors are at the center of strong geostrategic interests, and of the global technological race. For this reason, the Commission proposed the European Chips Act, which strengthens European competitiveness and resilience in this strategic sector... Recent shortages of semiconductors have highlighted Europe's dependency on a limited number of suppliers outside of the EU, in particular Taiwan and South-East Asia for manufacturing of chips, and the United States for their design. To respond to critical dependencies, the European Chips Act will strengthen manufacturing activities in the Union, stimulate the European design ecosystem, and support scale-up and innovation across the whole value chain. Through the European Chips Act, the European Union aims to reach its target to double its current global market share to 20% in 2030. ...In addition to the Chips for Europe Initiative, the second pillar of the European Chips Act will incentivise public and private investments in manufacturing facilities for chipmakers and their suppliers. This will contribute to the overall public investments in the sector estimated at EUR 43B." Publicly traded companies in the space include AMD (AMD), Intel (INTC), Marvell (MRVL), Microchip (MCHP), Micron (MU), Nvidia (NVDA), Qualcomm (QCOM) and Texas Instruments (TXN). Reference Link
ISRG

Hot Stocks

17:04 EDT Intuitive Surgical raises FY23 procedure growth to up 18%-21% from 12%-16% - Sees FY23 gross profit margin 68%-69%. Sees FY23 operating expense growth 11%-15%.Sees FY23 tax rate 22%-24%. Says core business remains strong. Says saw surprising procedure strength in the quarter. Says U.S. performance was above trend. Says hospitals working through staffing restraints. Says expects to launch Ion in the UK as first entry into Europe. Says focused on increased adoption for procedures. Says pursuing expanded indications for new platforms. Says January and February were particularly strong. Says expects customers to be cautious in overall capital spending. Says operating expenses were moderately above expectations. Comments taken from Q1 earnings conference call.
FOXA FOX

Hot Stocks

16:54 EDT Fox News Media confirms settlement reached in Dominion Voting Systems lawsuit - FOX News Media announced that a settlement was reached in the Dominion Voting Systems lawsuit. In making the announcement, the network said, "We are pleased to have reached a settlement of our dispute with Dominion Voting Systems. We acknowledge the Court's rulings finding certain claims about Dominion to be false. This settlement reflects FOX's continued commitment to the highest journalistic standards. We are hopeful that our decision to resolve this dispute with Dominion amicably, instead of the acrimony of a divisive trial, allows the country to move forward from these issues."
RMAX

Hot Stocks

16:49 EDT RE/MAX Holdings reports March home inventory was 56.4% higher year over year - March home sales jumped 37.7% over February, signaling the start of the peak spring and summer seasons in the report's 52 metro areas. While inventory was down 2.8% from February's total, March inventory was 56.4% higher year over year - due in part to the combination of pending sales and closings being down, leaving homes on the market longer than they were a year ago. The median sales price of $396,000 in March was down 2.0% year over year." Compared to last year, there's a lot to like about this housing market, including lower prices and less competition for available listings. Although it would be good to see more new listings coming onto the market, the current conditions offer potential for home buyers and sellers alike," says RE/MAX President and CEO Nick Bailey. "For those interested in selling, demand for properties remains high and for buyers entering the market, this spring can be a prime time to make a move."
ALTR

Hot Stocks

16:46 EDT Chairman of Altair Engineering Scapa sells 10K shares of company stock - The Chairman of Altair Engineering James Scapa disclosed in a regulatory filing that he had sold 10,000 shares of company stock at $70.33 per share on April 17 for a total transaction amount of $703,294.
WAL

Hot Stocks

16:46 EDT Western Alliance jumps 15% to $37.59 after Q1 results beat estimates
OPGN

Hot Stocks

16:37 EDT OpGen teams with Fisher Healthcare on U.S. distribution pact for Unyvero - OpGen announced that the Company has entered into a non-exclusive distribution agreement with Fisher Healthcare, a part of Thermo Fisher Scientific. The agreement is for the distribution of OpGen's Unyvero A50 platform and in vitro diagnostic tests for bacterial pneumonia as well as its research use only test for urinary tract infection .The Unyvero LRT cartridge for hospitalized patients with suspected pneumonia is the first ever FDA cleared IVD product specifically targeting bacterial pneumonia and antimicrobial resistance markers. The Unyvero UTI cartridge has recently completed its pivotal clinical trial and OpGen has recently submitted a De Novo classification request for Unyvero UTI to the FDA. The Unyvero UTI product is available as a RUO test to laboratories that do their own validation. Under the distribution agreement, Fisher Healthcare will have access to the Unyvero A50 platform and products to distribute and sell to hospitals and laboratories across the United States.Oliver Schacht, Chief Executive Officer of OpGen, commented, "We are very excited about the strategic distribution partnership with Fisher Healthcare as we believe the partnership will increase our Unyvero platform's commercial presence and footprint across the U.S. We view this expansion in our commercial channel strategy as the next step towards driving commercial adoption of Unyvero in the U.S. and achieving our revenue growth objectives in the coming years."
WAL

Hot Stocks

16:35 EDT Western Alliance reports Q1 net interest margin 3.79% vs. 3.32% last year - Reports Q1 ROE 1.43% vs. 1.64% last year and CET1 ratio of 9.4% vs. 9.0% last year.
NFLX

Hot Stocks

16:32 EDT Netflix raises FY23 free cash flow view to 'at least' $3.5B - Netflix said in its quarterly letter: "Net cash generated by operating activities in Q1 was $2.2B vs. $0.9B in the prior year period. Free cash flow, or FCF, in Q1 totaled $2.1B compared with $0.8B in last Q1. Assuming no material swings in F/X, we now expect at least $3.5B of FCF for the full year 2023, up from our prior expectation of at least $3.0B. This reflects lower cash spend on content than we originally forecasted, resulting in a year over year decrease in cash content spend, bringing our 2023 cash content to content amortization ratio closer to 1.0x in 2023. For 2024, we still expect our cash content spend to be in the range of roughly $17B, consistent with our prior expectations for the 2022-2024 period."
LICY

Hot Stocks

16:32 EDT Li-Cycle restates financial statements for FY22 - The company states: "The Company determined that unrealized fair value gains on financial instruments resulting from fair value revaluations of the conversion feature of the Company's convertible debt and warrants were understated by $18.2 million for the two months ended December 31, 2021. As a result, corresponding adjustments have been made to the Statements of income and comprehensive income and Statements of cash flows for the two months ended December 31, 2021 and corresponding notes. These adjustments result in an increase of $18.2 million in Other income, Net income before taxes, Net income attributable to shareholders of Li-Cycle, and Net income and comprehensive income; an increase in Earnings per common share of $0.12; and an increase in Earnings per common share of $0.11, for the two months ended December 31, 2021. The results pertaining to the two months ending December 31, 2022 are unchanged."
CAAP

Hot Stocks

16:31 EDT Corporacion America Airport reports March passenger traffic up 33.6% y/y - Corporacion America Airports reported a 33.6% YoY increase in passenger traffic in March 2023, reaching 91.7% of March 2019 levels. Total passenger traffic grew 33.6% compared to the same month of 2022, supported by an ongoing recovery in travel demand after the Covid-19 pandemic, as reflected by higher load factors and the gradual resumption of routes and frequencies across all countries of operations. Overall passenger traffic reached 91.7% of March 2019 levels, up from the 88.1% posted in February, with international and domestic passenger traffic reaching 92.7% and 92.4% of March 2019 levels, respectively.
WE

Hot Stocks

16:31 EDT WeWork discloses continued listing notice from NYSE - WeWork "announced that on April 12, 2023, it received a notice from the New York Stock Exchange notifying the Company that it is not in compliance with the NYSE's continued listing standards because as of April 11, 2023, the average closing price of the Company's Class A Common Stock was less than $1.00 per share over a consecutive 30 trading-day period. The Notice does not result in the immediate delisting of the Company's Common Stock from the NYSE. The Company intends to respond to the NYSE within ten business days of receipt of the Notice affirming its intent to cure the deficiency. Pursuant to the NYSE's rules, the Company has a six-month period following receipt of the Notice to regain compliance with the NYSE's minimum share price requirement."
EAF

Hot Stocks

16:31 EDT GrafTech expands operations with new sales office in Dubai - GrafTech International announced the opening of a new sales office in Dubai, United Arab Emirates. "The opening of our new sales office in Dubai reflects our commercial strategy to operate with a global footprint," commented Inigo Perez, Senior Vice President, Commercial and CTS. "With experienced sales and customer service teams around the world, we are committed to offering comprehensive support to GrafTech's customers located across the globe." "This expansion in Dubai reflects our dedication to the region at this important period of economic transformation for the area," added Richard Salameh, GrafTech's Sales Director for the Middle East and North Africa regions. "We look forward to providing the best possible commercial, customer service and technical support to our customers in the Middle East."
CDW

Hot Stocks

16:25 EDT CDW falls 8% after negative Q1 revenue pre-announcement - Shares of CDW are down 8% or $15.29 afterhours at $175.00 after the company guided Q1 revenue below consensus and also forecast FY23 to be modestly below $9.79 reported in FY22 against consensus of $10.39.
FOX FOXA

Hot Stocks

16:20 EDT Fox News reaches settlement pact with Dominion over defamation suit - Fox News struck a last-minute settlement agreement with Dominion Voting Systems, which claimed in a defamation lawsuit that the network pushed conspiraces that hurt the company, according to media reports. The judge in the case said the matter was resolved, though the details of the settlement are not yet known.
MBSC

Hot Stocks

16:19 EDT M3-Brigade approves extension period for business combination - M3-Brigade Acquisition III announced that, upon the request of the Company's sponsor, M3-Brigade Sponsor III LP, its board of directors has approved an extension of the period of time the Company has to consummate its initial business combination by three months, from the current deadline of April 26 until July 26, pursuant to the Company's amended and restated certificate of incorporation. In connection with the Extension, the Sponsor, or its affiliates or designees will deposit an additional $1,696,500 into the Company's trust account, in part from the Company's working capital, for the benefit of the Company's public stockholders. The Company's stockholders are not entitled to vote on or redeem their shares in connection with the Extension. The Sponsor has informed MBSC that it intends to request additional extensions of the period of time the Company has to consummate its initial business combination, to the extent necessary to complete its previously announced business combination with Greenfire Resources. The Charter permits a total of four three-month extensions, of which this is the third.
CUTR

Hot Stocks

16:17 EDT Plants, Mowry say Cutera special committee made 'misleading' statements - J. Daniel Plants, Founder and Chief Investment Officer of Voce Capital Management LLC and a member of the Board of Directors of Cutera, Inc., and David Mowry, also a Cutera Director - who together own approximately 7.0% of the outstanding shares of Cutera - issued the following statement in response to a recent press release from the Special Committee of Cutera's Board: "The events of the past week, particularly the wrongful termination of our roles as Executive Chairman and CEO, respectively, have only further solidified the need for meaningful Board change at Cutera. The press release issued yesterday by Gregory Barrett, Sheila Hopkins, Timothy O'Shea, Juliane Park and Janet Widmann (the "Entrenched Directors") contains numerous misleading, incomplete and untrue statements. The Entrenched Directors' revisionist history is contradicted by the actual decisions they made and actions they carried out."
SENS

Hot Stocks

16:16 EDT Senseonics announces first pediatric study participant in ENHANCE trial - Senseonics Holdings "announced the first pediatric study participant has been inserted with Eversense(R) 365-day system as part of the pivotal ENHANCE clinical trial at the AMCR Institute, a clinical research center focused on pre-diabetes, type 1, type 2 diabetes and obesity, under the direction of Dr. Timothy Bailey. The ENHANCE Trial is designed to evaluate the accuracy and safety of the Eversense system for up to one year. Over 165 adult subjects were inserted with Eversense systems in four centers across the United States. Enrollment for the 365-day sensor configuration was completed in September 2022 and the last patient is expected to complete their 365-day visit during the third quarter of 2023. Data gathered in this trial is also planned to be used to submit for the integrated continuous glucose monitoring, iCGM, designation in 2023. An investigational device exemption supplement was submitted and approved for expansion of the trial to allow for pediatric patients 14 to 18 years of age and the first pediatric study participants were enrolled in Q2 2023."
SAIC

Hot Stocks

16:15 EDT SAIC and GomSpace announce strategic partnership - Science Applications International and GomSpace Group signed a strategic partnership to provide government and commercial customers in the Americas with new space-based mission capabilities leveraging CubeSat's and SmallSats. This partnership combines SAIC's expansive mission domain knowledge, engineering, software, and integration capabilities, with GomSpace's spacecraft technologies to achieve best-in-class solutions which can be rapidly deployed. The partnership will also deliver system elements such as software products, spacecraft components, fully integrated spacecraft, reliable in-orbit services and mission operations. SAIC becomes the exclusive U.S. integrator of GomSpace satellites and licensed product distributor, services reseller and space vehicle and mission integrator for GomSpace's U.S. Government customers. The agreement, a Memorandum of Understanding, was signed at the Space Symposium in Colorado Springs, by David Ray, SAIC Senior Vice President of Space, and Frank Tobin, Executive Chairman of GomSpace North America.
CLPT

Hot Stocks

16:14 EDT ClearPoint Neuro with teams with NE Scientific on software solution - ClearPoint Neuro announced an exclusive worldwide agreement with NE Scientific a leader in biophysics simulation, to develop a GPU-accelerated software solution for modeling of drug infusions delivered with the ClearPoint SmartFlow cannula. Under the terms of the agreement, this first of many software collaborations will enable simulation of patient-specific infusion in real time to predict the distribution of therapeutic agents in 4D before the actual procedure. Coupled with Maestro, this new software will allow optimization of infusion parameters including target points, flow rate, infusion coverage and leakage outside of target-specific boundaries. The simulation software will require standard structural and diffusion pre-operative MRI scans. Infusions can be planned either in the pre-operative MRI space and registered to intra-operative MRI case data, or in the OR space using an intra-operative CT. "The accuracy of the ClearPoint system allows for precise dosing and targeted delivery of therapeutic agents across the blood brain barrier. Real time simulation of patient-specific infusion would be of tremendous help to neurosurgeons performing these procedures. It presents a unique opportunity for optimization and monitoring of infusion parameters, including cannula tip location, flow rate, and percentage coverage," commented Lyubomir Zagorchev, Vice President, Clinical Science and Applications at ClearPoint Neuro. "Accurate patient-specific quantification and visualization of infusion coverage has the potential to change the current practice of setting up fixed clinical protocols for pharma trials. The dose of delivered therapeutic can be visualized and quantified during a procedure based on patient-specific data. That will reduce variability that may lead to sub-optimal delivery, and even failed clinical trials."
UAL

Hot Stocks

16:13 EDT United Airlines sees FY23 capacity growth high teens y/y - Sees FY23 CASM-ex about flat; adjusted net debt to EBITDAR less than 3.0x.
UAL

Hot Stocks

16:13 EDT United Airlines sees FY23 CapEx about $8.5B
UAL

Hot Stocks

16:12 EDT United Airlines sees Q2 CASM-ex flat to up 2% y/y
ADEA

Hot Stocks

16:11 EDT Adeia announces Christina Sawyer as chief people officer - Adeia announced that Christina Sawyer joined Adeia (ADEA) as the company's chief people officer on Monday, April 17. Sawyer joins Adeia from Electronic Arts (EA), where she was most recently vice president of integrated operations.
UAL

Hot Stocks

16:10 EDT United Airlines sees Q2 capacity growth about 18.5% y/y
FNCH

Hot Stocks

16:09 EDT Finch enters CP101 clinical trial agreement with Brigham and Women's Hospital - Finch Therapeutics announced that it has entered into a clinical trial agreement with Brigham and Women's Hospital for the evaluation of CP101 in ulcerative colitis. The company also announced updates to its license agreement with the University of Minnesota. Under the clinical trial agreement, Brigham and Women's Hospital will conduct an investigator-sponsored trial that is designed to compare two doses of CP101 in patients with mild-to-moderate ulcerative colitis. The study is designed to generate data on safety, pharmacokinetics, pharmacodynamics and clinical efficacy, and aims to build on a growing body of evidence supporting the role of the microbiome in improving outcomes for patients suffering from ulcerative colitis. Topline data from this clinical study is anticipated in 2025. The company also announced that it has amended its license agreement with the University of Minnesota, through which Finch has exclusively licensed 13 issued patents and 7 patent applications covering specific approaches to formulations comprising human fecal microbes, methods of increasing microbiota diversity, and methods of decreasing the relative abundance of certain bacteria. A key feature of the amendment allows Finch to satisfy certain performance milestones through sublicensing agreements, aligning with Finch's new strategic focus on collaborations and partnerships.
FLGC

Hot Stocks

16:08 EDT Flora Growth names Hussein Rakine CEO - Flora Growth Corp. announced that its board of directors accepted the resignation of Luis Merchan as Chairman of the Board and the company's Chief Executive Officer. To fill the vacancies created by Mr. Merchan's resignation, the Board has appointed JustCBD founder, Hussein Rakine, as CEO and member of the board of directors. Of the appointment, former-Chairman and CEO, Luis Merchan said, "At Flora we have consistently placed human capital as a critical part of our M&A strategy. That's why today we are honored to have the former founder of a company we acquired last year join the Board and be named as CEO. I believe Hussein's appointment will ensure continued growth within the Company." "I am enthusiastic about collaborating with our board of directors, executive team, and all stakeholders to bring Flora's business plan to fruition," said Hussein Rakine. "In a nascent industry such as ours, it's critical to stay nimble- and that is what I intend to do as I lead Flora into the next phase of growth. I would like to express our sincere appreciation to Luis for his unwavering commitment and dedication to the Company during his tenure. We wish him all the best in his future endeavors."
CLXT

Hot Stocks

16:07 EDT Calyxt announces effectiveness of registration statement on Form S-4 - Calyxt and Cibus announced that the registration statement on Form S-4, initially filed with the U.S. SEC by Calyxt on February 14, and amended on April 14, has been declared effective by the SEC. The proxy statement/prospectus contains important information about the proposed merger transactions, the merger agreement and the proposals to be considered at the Special Meeting. The combined company is expected to be renamed Cibus, Inc. and remain listed on the Nasdaq Capital Market under the proposed ticker symbol CBUS.
BILL

Hot Stocks

16:07 EDT Bill names Ken Moss CTO - Bill announced that Ken Moss has joined the company as Chief Technology Officer. Moss reports directly to CEO and Founder Rene Lacerte and succeeds Vinay Pai who is retiring as CTO after five years with the company. "We are excited to welcome Ken to BILL. As an experienced technology leader, Ken has led global teams to create innovative solutions that anticipate customers' needs and help them succeed," said Rene Lacerte, CEO and Founder of BILL. "As a category creator and leader, BILL is transforming the future of finance for SMBs. Cutting-edge technology and innovation are at the center of what we do and how we deliver for SMBs, and Ken's experience with enabling breakthrough technology at speed and scale will help us accelerate value creation for customers."
NFLX

Hot Stocks

16:07 EDT Netflix down 9% following quarterly report - Netflix shares are down $28.81, or nearly 9%, to $304.89 in after-hours trading.
NFLX

Hot Stocks

16:05 EDT Netflix sees constant currency revenue growth to accelerate over second half - Netflix said: "We expect constant currency revenue growth to accelerate over the course of the second half of 2023 as we continue to improve our service, more broadly roll out paid sharing in Q2 and grow our advertising business. We also expect year over year operating profit growth and operating margin expansion for the full year (assuming no material swings in F/X). We're still targeting a 2023 operating margin of 18%-20%, based on F/X rates as of January 1, 2023. We believe our ability to deliver on our long term financial targets will hinge on 1) growing engagement and 2) improving our monetization to fuel revenue growth and increased profitability."
AJRD

Hot Stocks

16:04 EDT Aerojet Rocketdyne delivers propulsion for Artemis III mission - Aerojet Rocketdyne recently completed the four RS-25 engines that will power the core stage of NASA's super heavy-lift Space Launch System SLS rocket during the historic Artemis III mission. Slated for launch around the middle of the decade, Artemis III is a planned lunar landing mission that will return humans to the surface of the Moon for the first time in more than 50 years. "The Artemis III mission is pivotal in our nation's goal to return American astronauts to the surface of the Moon, establish a sustained presence there and pave the way for crewed missions to Mars," said Eileen P. Drake, Aerojet Rocketdyne CEO and president. "As our nation makes this next giant leap in its space program, it is leveraging the extensive knowledge and lessons learned that were gained during our earlier exploration efforts, including the Apollo, Space Shuttle and Artemis I missions. We are truly standing on the shoulders of those who pioneered the exploration of deep space." The four RS-25 engines that will power the SLS rocket's core stage during the Artemis III mission have been upgraded following their service during the shuttle program and will now generate about 2 million pounds of combined thrust. The Artemis III RS-25 engines safely flew 138 individual astronauts to orbit and supported 26 Space Shuttle missions.
NFLX

Hot Stocks

16:04 EDT Netflix shifting 'broad launch' of paid sharing to Q2 from late Q1 - Netflix said in its quarterly letter to investors: "We're pleased with the most recent launches of paid sharing, and while we could have launched broadly in Q1, we found opportunities to improve the experience for members. We learn more with each rollout and we've incorporated the latest learnings, which we think will lead to even better results. To implement these changes, we shifted out the timing of the broad launch from late Q1 to Q2. While this means that some of the expected membership growth and revenue benefit will fall in Q3 rather than Q2, we believe this will result in a better outcome for both our members and our business (more details in the Monetization and Revenue section). The majority of our year over year F/X neutral revenue growth in Q2 is expected to come from growth in our paid membership base. This translates into Q2 paid net adds that are roughly similar to Q1'23 and a slight increase in year over year F/X neutral ARM (limited price increases during paid sharing rollout). We forecast Q2'23 operating income of $1.6B (roughly flat year over year) and an operating margin of 19% vs. 20% in Q2'22. The year over year decline in operating margin is attributable to the appreciation of the US dollar against most other currencies over the past year."
UAL

Hot Stocks

16:04 EDT United Airlines reduced adjusted total debt by $4.6B in the last 12 months
UAL

Hot Stocks

16:03 EDT United Airlines reports Q1 capacity up 23.4% vs. 1Q22 - Q1 TRASM up 22.5% compared to first-quarter 2022. Q1 CASM up 4.0%, and CASM-ex down 0.1%, compared to first-quarter 2022.
HWC

Hot Stocks

16:03 EDT Hancock Whitney reports Q2 deposits $29.6B, up 2% from Q4 - Q1 average deposits were $28.8B, "virtually unchanged linked-quarter".
UAL

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16:02 EDT United Airlines seeing strong international demand in Q2 - Says international expansion twice the rate of domestic. Cost trajectory on track for full-year flat CASM-ex target.
NFLX

Hot Stocks

16:02 EDT Netflix reports Q1 global streaming paid net additions of 1.75M - Netflix said in its quarterly letter to investors: "Paid net adds amounted to 1.8M for Q1 vs. -0.2M in the year ago quarter."
GE

Hot Stocks

15:55 EDT GE Aerospace, AJW Group sign systems services agreement - GE Aerospace has signed an agreement with AJW Group to support avionics and electrical power systems across the B777, B737 and A320/30/40 family of aircraft. The contract will start this year and will cover all AJW Group's Europe, Middle East, and Africa customers that fly the B777, B737 and A320/30/40 family of aircraft. "We are committed to supporting our MRO customers' growing demands," said John Haigh, Electrical Power and Controls leader at Cheltenham for GE Aerospace. "As airlines continue to expand their fleets, we've taken aggressive actions to strengthen lead time, supply availability and delivery for our customers." GE Aerospace was selected for the three-year agreement based on turnaround time and repair capability. GE Aerospace will service the systems at their repair and maintenance location in Cheltenham, United Kingdom.
NFLX

Hot Stocks

15:35 EDT Netflix to wind down DVD.com later this year - Netflix Co-CEO Ted Sarandos stated in a post to the company's newsroom: "After an incredible 25 year run, we've decided to wind down DVD.com later this year. Our goal has always been to provide the best service for our members but as the business continues to shrink that's going to become increasingly difficult. So we want to go out on a high, and will be shipping our final discs on September 29, 2023. Those iconic red envelopes changed the way people watched shows and movies at home - and they paved the way for the shift to streaming... We feel so privileged to have been able to share movie nights with our DVD members for so long, so proud of what our employees achieved and excited to continue pleasing entertainment fans for many more decades to come." Reference Link
GM

Hot Stocks

15:10 EDT DOJ secures settlement pact with GM over immigration-related discrimination - The Justice Department announced that it has secured a settlement agreement with General Motors to resolve the department's determination that GM discriminated against non-U.S. citizens in violation of the Immigration and Nationality Act. The department also announced the release of a new fact sheet to help employers avoid citizenship status discrimination when complying with export control laws, which govern U.S. companies' ability to export certain goods and software, technology and technical data. The department's investigation of GM revealed that the company's violations stemmed in part from its failure to properly consider the INA's nondiscrimination requirements when also complying with export control laws. The department's investigation determined that until at least September 2021, GM's export compliance assessments unnecessarily required lawful permanent residents to provide an unexpired foreign passport as a condition of employment, imposing a discriminatory barrier on them in the hiring process. From at least July 2019 until May 2021, GM improperly combined its process for verifying workers' permission to work in the United States with its export compliance assessment, which resulted in GM unnecessarily requiring that newly hired non-U.S. citizens provide specific and unnecessary documents to prove their permission to work. Under the terms of the agreement, GM will pay $365,000 in civil penalties to the United States. The agreement also requires GM to train its personnel on the INA's requirements, revise its employment policies and be subject to departmental monitoring and reporting requirements. Specifically, GM must separate its process to verify permission to work in the United States from its export compliance assessment process, and stop requiring lawful permanent residents to present foreign passports as a condition of employment. []:[https://www.justice.gov/opa/pr/justice-department-secures-agreement-general-motors-and-announces-new-resource-help-employers]
SEIC

Hot Stocks

14:44 EDT SEI Investments increases stock repurchase program by $250M - The board of directors of SEI Investments approved an increase in its stock repurchase program by an additional $250M, increasing the available authorization under the program to approximately $263M, the company announced.
TIG

Hot Stocks

14:43 EDT Trean Insurance reports stockholders approve proposed merger - Trean Insurance Group announced that the company's stockholders approved the agreement and plan of merger entered into by the company with affiliates of Altaris, providing for the proposed merger of the company with an affiliate of funds managed by Altaris. The company currently anticipates that the proposed transaction will be completed in April.
SABS

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14:34 EDT SAB Biotherapeutics spikes 33% after FDA grants BTD to SAB-176 - Shares of SAB Biotherapeutics are up 33% or 25c per share to $1.02 in late afternoon trading on Tuesday after the immunotherapies biopharma announced that the U.S. Food and Drug Administration, FDA, had granted Breakthrough Therapy Designation, BTD, to SAB-176, an investigational therapeutic, for post-exposure prophylaxis for Type A and Type B influenza illness in high-risk patients, including those who have anti-viral resistant strains.
DNA

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14:10 EDT Ginkgo Bioworks jumps 2% after announcing collaboration with Cambrium complete - Ginkgo Bioworks is up 1.7% or 2c per share to $1.24 per share, just shy of its intraday high on Tuesday afternoon, after announcing that German start-up Cambrium and Ginkgo Bioworks successfully completed their collaboration. Through the partnership, Cambrium and Ginkgo combined their capabilities to enable the rapid and cost-effective design of high performing, industrially relevant microbes for protein production.
RYAHF

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13:48 EDT RYAH Group enters Master Distribution Agreement with OMNI - RYAH GROUP and OMNI Medical Services have signed a Master Distribution Agreement, whereby OMNI will supply RYAH's solutions for use in US clinical trials and research studies of medical cannabis. OMNI Medical Services has signed a non-exclusive master distribution agreement, enabling OMNI to market and sell the RYAH Group's products in support of clinical research trials and studies throughout the United States. RYAH and OMNI would also like to update regarding an October 26, 2021 announcement of a non-binding letter of intent for RYAH to acquire 100% of the business and assets of Omni. Both parties agree that the potential acquisition is not of interest at this time, whereas the business synergies and collaboration potential continue to be of significant interest. RYAH would also like to update that it has received a second comment letter from the Ontario Securities Commission regarding the Failure-to-File Cease Trade Order issued under National Policy 11-207. The OSC have requested further clarifications on documents submitted to date, which RYAH management is working to address, hoping to obtain the revocation of the FFCTO as soon as possible. RYAH will keep investors updated with regular news releases
XPEV

Hot Stocks

13:37 EDT XPeng debuts G6 Ultra Smart Coupe SUV at Auto Shanghai 2023 - XPeng announced the debut of its fifth smart EV model, the XPeng G6 Ultra Smart Coupe SUV, at Auto Shanghai 2023. The first production model based on the Company's next-generation smart electric platform architecture, SEPA2.0, the G6 delivers XPeng 's latest smart driving, intelligent cabin, superfast charging and superior performance features. It will be equipped with the latest XNGP as a final stage of ADAS or Advanced Driver Assistance System, before fully realizing autonomous driving. Aspiring to create a dream car for the younger generation, this new-breed model features a striking body design with a new concept of tech-fluid aesthetics to satisfy customers' sense of style, as well as their requirements for responsive handling, copious interior space, and immersive comfort and infotainment amenities. XPeng G6 coupe SUV comes equipped with the Company's world-class, 800V high-voltage SiC platform and 3C battery cells, China's only mass-produced front and rear integrated aluminum body die-casting technology, and CIB battery-body integration technology. This groundbreaking model is anticipated to set the mid-sized BEV SUV segment's new benchmarks for smart superiority, range reliability, handling excellence and physical comfort. "G6 is born intelligent, conceived through XPENG's technological ingenuity and relentless innovation to continuously set new industry standards in the era of smartification," said Mr. He Xiaopeng, Chairman & CEO of XPENG. "We aspire to redefine the mobility experience of a broad customer base with streamlined configurations, outstanding performance, a unified immersive product experience and efficient development iterations."
MBRX

Hot Stocks

13:37 EDT Moleculin Biotech reports preclinical data on Annamycin - Moleculin Biotech announced that "positive" preclinical data regarding the company's next-generation anthracycline, Annamycin, was presented at the American Association for Cancer Research, or AACR, Annual Meeting 2023. ANN exhibited significantly higher accumulation in the liver parenchyma when compared to DOX, or 6-fold higher AUC values, the company reported. "Researchers observed clear inhibition of the subcutaneous tumor growth after systemic administration of L-ANN," the company stated. "Annamycin has continued to demonstrate in preclinical models promising results in hard-to-treat tumors. We are pleased with the findings from these preclinical models in HCC, the most common type of primary liver cancer that is responsible for more than 12,000 deaths per year in the US. The high antitumor activity seen preclinically with Annamycin is very encouraging and provides validation for expanded studies to assess activity in different tumor liver metastasis models as well as HCC models," commented Walter Klemp, Chairman and CEO of Moleculin.
INKT

Hot Stocks

13:35 EDT MiNK Therapeutics announces clinical data of allogeneic iNKT cells - MiNK Therapeutics presented data at the American Association of Cancer Research annual meeting, demonstrating the clinical benefit of allo-iNKTs, agenT-797, alone and in combination with anti-PD-1 in patients with refractory non-small cell lung cancer, testicular, and gastric cancers. In a phase 1/2 trial, patients received a single infusion of agenT-797, alone or in combination with pembro or nivo, without lymphodepletion. Patients were heavily pretreated with a median of 4 prior lines of therapy and were unresponsive to prior anti-PD-1 therapy. The results showed that agenT-797 promoted durable responses, including a partial response and tumor reduction of greater than42% which was ongoing at 9 months in a patient with metastatic gastric cancer who had no response to prior treatment with pembro or nivo plus FOLFOX. Additionally, durable disease stabilization and biomarker responses were observed in NSCLC and testicular cancers refractory to anti-PD-1. AgenT-797 was persistent and detectable in the periphery for greater than ~8 weeks and tolerable up to 1000x106 cells, with no neurotoxicity, dose-limiting toxicities, or severe cytokine release syndrome. Administration of agenT-797 induced a systemic and local anti-tumor response, driving immune cell infiltration into tumors and promoting immune cell activation. MiNK Therapeutics will further evaluate agenT-797 through phase 1/2 expansion trials in combination with standard of care agents with or without botensilimab in relapsed/refractory NSCLC, testicular cancer, and in 2L gastric cancer through a phase 1/2 investigator sponsored trial led by Dr. Yelena Janjigian, Chief Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center.
KPTI

Hot Stocks

13:34 EDT Karyopharm announces updated results from Phase 1 study of Selinexor - Karyopharm Therapeutics announced updated results from the Phase 1 study evaluating the safety and efficacy of once-weekly selinexor in combination with ruxolitinib in patients with treatment-naive myelofibrosis. The data, featured in a poster presentation at the American Association for Cancer Research, or AACR, Annual Meeting 2023, "show that rapid, deep and sustained spleen responses and robust symptom improvement were achieved at both weeks 12 and 24, in patients treated with selinexor 60mg in combination with ruxolitinib," the company said. As of the February 24, 2023 data cut-off date, 24 patients had been assigned to either a 40mg or 60mg once weekly dose of selinexor, combined with ruxolitinib. All patients initiated treatment greater than 24 weeks prior to the data cut-off date. Both the efficacy and safety data support the 60 mg dose of selinexor as the recommended dose in combination with ruxolitinib. A double-blind, randomized, Phase 3 trial of selinexor 60 mg in combination with ruxolitinib versus placebo in combination with ruxolitinib in JAKi treatment-naive patients with myelofibrosis is expected to initiate in the first half of 2023. "We are enthusiastic about the impressive spleen volume reductions and robust symptom improvement observed with the 60mg dose of selinexor and ruxolitinib combination at week 24, which represent very meaningful improvements relative to the current standard of care of ruxolitinib alone. These data suggest that the combination of selinexor and ruxolitinib has the potential to be a transformative therapy for first line myelofibrosis patients. We are also very encouraged by the preliminary data showing rapid normalization in platelets and stability of hemoglobin levels, as potential evidence of disease modification for these patients. We look forward to building upon these findings as we plan the initiation of a pivotal Phase 3 study in front-line myelofibrosis later this quarter," said Reshma Rangwala, MD, PhD, Chief Medical Officer of Karyopharm.
HARP

Hot Stocks

13:33 EDT Harpoon Therapeutics presents preclinical results for HPN217, HPN328 - Harpoon Therapeutics presented preclinical data for two of its key clinical programs, HPN328 and HPN217, in three poster presentations at the American Association for Cancer Research Annual Meeting being held in Orlando, Fla., April 14-19, 2023. HPN217 targets B-cell maturation antigen and is based on Harpoon's proprietary Tri-specific T cell Activating Construct platform designed to recruit a patient's own immune cells to kill tumor cells. HPN328 is Harpoon's half-life extended TriTAC that targets delta-like canonical Notch ligand 3. Abstract #4131: Long-term anti-tumor immunity induced by HPN328, a DLL3-targeting tri-specific, half-life extended T cell engager, in a preclinical immunocompetent mouse model: In an immunocompetent MC38-hDLL3 murine cancer model, HPN328 showed dose dependent anti-tumor activity and increased CD8+ tumor infiltrated lymphocyte activation which was maintained upon reintroduction of a second tumor on the opposite flank, and discontinuing treatment. These results suggested that HPN328 can induce epitope spreading and prolonged anti-tumor immunity, with an increase in memory T cells, suggesting a novel mechanism for its activity and efficacy in vivo. Overall, these findings indicate that long-term anti-tumor immunity induced by HPN328 can potentially lead to more durable anti-tumor responses in cancer patients. Abstract #5070: Anti-tumor activity of HPN328, a DLL3-targeting tri-specific, half-life extended T cell engager, is enhanced by combining with an anti-PD-L1 antibody in an immunocompetent mouse model: In an immunocompetent mouse model, sub-therapeutic doses of HPN328 in combination with an anti-PD-L1 antibody demonstrated enhanced, dose dependent anti-tumor activity when compared to either treatment alone and showed increased activation in memory CD8+ T cells. These results demonstrate the utility of combining anti-PD-L1 antibodies to enhance the anti-tumor activity of HPN328 and further supports investigation of this combination approach in patients. Clinical studies of HPN328 in combination with atezolizumab are planned. Abstract #5081: Anti-tumor activity of HPN217, a BCMA-targeting tri-specific T cell engager, is enhanced by gamma-secretase inhibitors in preclinical models gamma-secretase inhibitors have been shown to increase membrane bound BCMA expression on multiple myeloma cells, providing a rationale for studying this combination approach. In preclinical mouse models, gamma-secretase inhibitors increased the potency of HPN217 in vitro in multiple cell lines. Specifically, combination therapy with 1mg/kg LY-3039478 and a subtherapeutic dose of 4ug/kg HPN217 led to decreased tumor burden and increased survival in a disseminated MOLP8 xenograft compared to either monotherapy alone.
UFAB

Hot Stocks

13:15 EDT Unique Fabricating trading resumes
VERB

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13:01 EDT Verb Technology announces stockholder approval of reverse split - Verb Technology Company announced that its Board of Directors authorized the stockholder approved 1-for-40 reverse stock split of its common stock shares and that the common stock shares will begin trading on a split-adjusted basis at the commencement of trading April 19, 2023. The company's shares will continue to trade on the Nasdaq Capital Market under the same symbol "VERB." The stockholders voted overwhelmingly in favor of authorizing the company's board of directors to institute a reverse stock split, the company said.
UFAB

Hot Stocks

12:25 EDT Unique Fabricating trading halted, news pending
CLNE TRMLF

Hot Stocks

12:17 EDT Clean Energy, Tourmaline enter $70M joint development agreement for CNG stations - Tourmaline Oil (TRMLF) and Clean Energy Fuels (CLNE) announced a $70M Joint Development Agreement to build and operate a network of compressed natural gas stations along key highway corridors across Western Canada. Through this 50-50 shared investment, Tourmaline and Clean Energy expect to construct and commission up to 20 CNG stations over the next five years, which will allow heavy-duty trucks and other commercial transportation fleets that operate in the area to transition to the use of CNG, a lower carbon alternative to gasoline and diesel. Clean Energy will operate the stations. Based on the anticipated commissioning of up to 20 stations over the next five years, approximately 3,000 natural gas-powered trucks could be fueled using CNG every day, resulting in a reduction of approximately 72,800 tonnes of CO2 equivalent usage per year. This is equivalent to removing 15,690 passenger vehicles from the road. As future demand increases, the capacity of these stations can be expanded, and new stations added, which would result in greater environmental performance improvement. The first station expected to be jointly owned under the agreement, located north of Edmonton, is operational and well-positioned for heavy-haul transport routes with close proximity to key customers and stakeholders. The next stations which Tourmaline and Clean Energy expect to commission in the first half of 2024 are anticipated to be located within the municipalities of Calgary and Grande Prairie in Alberta and Kamloops, B.C.
AMPS

Hot Stocks

12:00 EDT Altus Power falls -6.5% - Altus Power is down -6.5%, or -33c to $4.69.
EBS

Hot Stocks

12:00 EDT Emergent BioSolutions falls -6.9% - Emergent BioSolutions is down -6.9%, or -81c to $10.90.
SJT

Hot Stocks

12:00 EDT San Juan Basin Royalty Trust falls -8.8% - San Juan Basin Royalty Trust is down -8.8%, or -91c to $9.46.
NU

Hot Stocks

12:00 EDT Nu Holdings rises 6.7% - Nu Holdings is up 6.7%, or 30c to $4.86.
SBSW

Hot Stocks

12:00 EDT Sibanye Stillwater rises 10.2% - Sibanye Stillwater is up 10.2%, or 88c to $9.48.
TDOC

Hot Stocks

12:00 EDT Teladoc rises 11.5% - Teladoc is up 11.5%, or $2.98 to $28.85.
LUV

Hot Stocks

11:35 EDT Southwest resumes operations, says pause due to 'firewall failure' - Southwest issued a statement to media after its pause in flights earlier this morning, stating: "Southwest has resumed operations after temporarily pausing flight activity this morning to work through data connection issues resulting from a firewall failure. Early this morning, a vendor-supplied firewall went down and connection to some operational data was unexpectedly lost. Southwest Teams worked quickly to minimize flight disruptions. We ask that travelers use Southwest.com to check flight status or visit a Southwest Airlines Customer Service Agent at the airport for assistance with travel needs. We appreciate the patience of our Customers and Employees during this morning's brief disruption."
BA

Hot Stocks

11:29 EDT Boeing sees 'encouraging' progress on 737 deliveries to China
BA

Hot Stocks

11:28 EDT Boeing doesn't see 737 issue changing long-term guidance, says CEO - CEO Dave Calhoun says Boeing hasn't altered its 737 supplier master schedule, including planned rate increases for the 737 MAX, because of the new issue. Comments taken from Boeing's Annual Shareholder meeting.
LUV

Hot Stocks

11:26 EDT FAA says pause on Southwest departures has been lifted - The Federal Aviation Administration said via Twitter, "This morning @SouthwestAir experienced a technical issue with one of their internal systems. At the airline's request, the FAA paused Southwest's departures as they resolved the issue. The pause has been lifted and their service has resumed."
SGAMY

Hot Stocks

11:23 EDT Sega to acquire Rovio Entertainment in EUR706M deal - Sega Sammy said it resolved to implement a tender offer to acquire Rovio Entertainment Oyj, a mobile game company headquartered in Finland, through Sega's wholly-owned UK subsidiary Sega Europe Limited and Sega Sammy Holdings has entered into a definitive agreement with Rovio pursuant to which the Tender Offer is made. Through the Tender Offer, Sega aims to acquire the entirety of Rovio's outstanding shares and options at EUR 9.25 per share and EUR 1.48 per option, or EUR 706M in total. The acquisition is a friendly takeover, as Rovio's board of directors has agreed to, and has expressed support towards the Tender Offer. Shareholders in Rovio who in aggregate hold shares corresponding to approximately 49.1% of the outstanding shares and votes in Rovio, have irrevocably undertaken to accept the offer, subject to certain customary conditions. The acquisition is expected to close in the second quarter of FY2024/3 and is contingent on the completion of reviews under applicable antitrust laws and other customary conditions. "Among the rapidly growing global gaming market, the mobile gaming market has especially high potential, and it has been SEGA's long-term goal to accelerate its expansion in this field," said Sega Sammy president and group CEO Haruki Satomi. "I feel blessed to be able to announce such a transaction with Rovio, a company that owns "Angry Birds", which is loved across the world, and home to many skilled employees that support the company's industry leading mobile game development and operating capabilities. Historically, as represented by the "Sonic the Hedgehog" series, SEGA has released countless video game titles to various gaming platforms. I am confident that, through combination of both companies' brands, characters, fanbase, as well as corporate culture and functionality, there will be significant synergies created going forward."
LMT

Hot Stocks

11:20 EDT Lockheed Martin expects return to growth in 2024, beyond - Says 'well-positioned' to meet commitments for the year. Says continues to strategically invest in growth strategy. Says cash deployment plan is 'on track'. Says expects cash deployment to accelerate throughout the year. Expects F-35 deliveries to be slower than previously anticipated. Says reaffirming guidance for all key metrics.
LMT

Hot Stocks

11:14 EDT Lockheed Martin remains on track to meet financial expectations for full year - Says had a 'solid start' to the year. Says anticipates heightened emphasis on national security. Says remains fully committed to developing hypersonic technology. Says demand for high-performing systems in RMS continues to be strong. Says continues to grow 'significant' partnership with Australia. Comments taken from Q1 conference call.
RLAY

Hot Stocks

11:10 EDT Relay Therapeutics trading resumes
LUV

Hot Stocks

10:48 EDT Southwest confirms ground stop implemented due to 'intermittent issues' - Southwest Airlines stated in a reply to a tweet from a customer: "We have had to implement a ground stop as a result of intermittent issues that were experienced, and we should hopefully be resuming our operation as soon as possible. I apologize for any inconvenience this may cause, but we'll be here for you if you need any assistance." Reference Link
RLAY

Hot Stocks

10:45 EDT Relay Therapeutics says RLY-2608 selectively targets multiple PI3Ka mutations - Relay Therapeutics announced initial clinical data for RLY-2608, the first known investigational allosteric, pan-mutant and isoform-selective inhibitor of PI3Kalpha. The data support initial clinical proof of mechanism, demonstrating that RLY-2608 achieved selective target engagement at multiple predicted efficacious doses with a favorable initial safety and tolerability profile. These data are being presented today at the American Association for Cancer Research Annual Meeting 2023. RLY-2608 is currently being evaluated in an ongoing dose-escalation portion of ReDiscover, a first-in-human trial, which was designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary antitumor activity across two separate arms. The monotherapy arm started in December 2021 and enrolled 19 patients with unresectable or metastatic solid tumors with a PI3Kalpha mutation. This arm included a broad diversity of solid tumors, predominantly tumor types not predicted to be sensitive to single agent PI3Kalpha inhibition. The RLY-2608 + fulvestrant combination arm started April 2022 and enrolled 23 patients with PI3Kalpha-mutant, HR+, HER2- locally advanced or metastatic breast cancer. Across both arms of the study, enrolled patients had received a significant level of prior therapy, including all breast cancer patients who had received at least one prior endocrine therapy and CDK4/6 inhibitor. The cut-off date for data reported at AACR was March 9, 2023. Among the 27 patients with breast cancer, 12 had kinase mutations, 10 had helical mutations and nine had other mutations. In the monotherapy arm, patients received seven different doses, ranging from 50mg twice daily to 400mg BID. In the combination arm, patients received five different BID doses, ranging from 100mg to 800mg BID. RLY-2608 reached selective target exposure at multiple doses, with target exposure being defined as continuous inhibition of mutant PI3Kalpha of approximately 80 percent or greater. This was reached at 400mg BID monotherapy and at 600mg BID and 800mg BID combination doses. RLY-2608 demonstrated mutant selective PI3Kalpha target engagement at multiple doses. There was limited observed impact on glucose homeostasis overall and no Grade 3 hyperglycemia was observed. Glucose homeostasis is believed to be an important indicator of both RLY-2608's clinical selectivity profile and its potential ability to avoid this key off-target toxicity associated with wild-type inhibition. Declines of PI3Kalpha mutations in ctDNA from patient samples support initial clinical validation of RLY-2608's ability to selectively inhibit a wide range PI3Kalpha mutations in a dose-dependent manner. RLY-2608 has been generally well tolerated in the 42 patients treated as of the cut-off date: The overall safety profile consisted of mostly low-grade adverse events that were manageable and reversible; Across all doses, there were no dose-limiting toxicities, no AEs leading to treatment discontinuation and no Grade 4-5 AEs; Among patients receiving doses at target exposures, AEs were mostly low-grade events that were manageable and reversible: No Grade 3 hyperglycemia, diarrhea, or rash, which are the AEs most commonly associated with treatment discontinuation for existing investigational and approved therapies; No dose reductions or discontinuations due to AE; The low rate of AE-related dose modifications allowed for median dose intensity of at least 98 percent across all dose levels. A patient with metastatic HR+/HER2- breast cancer, with two PI3Kalpha mutations, who progressed following 12 lines of prior therapy, including chemotherapy, endocrine and HER2-directed therapies, received RLY-2608 400mg BID monotherapy. An unconfirmed partial response by Response Evaluation Criteria in Solid Tumors was recorded at 8 weeks. Subsequent to the data cut-off, this partial response was confirmed, and the patient remains on treatment with no AEs reported as of April 4, 2023. Early anti-tumor activity was seen across a range of doses and across helical, kinase and other mutations, demonstrating selective target engagement of mutant PI3Kalpha. Among the 16 breast cancer patients with measurable disease: Nine experienced radiographic tumor reductions; 12 exhibited a best overall response of stable disease and 1 partial response; 11 remain on treatment as of the cut-off date; Median duration of treatment for all breast cancer patients was approximately 4 months: 70 percent remain on treatment as of the cut-off date; 600mg BID dose: approximately 4-month median follow-up; Six of seven 600mg BID patients remain on treatment.
LUV

Hot Stocks

10:41 EDT FAA says Southwest requested 'pause' of airline's departures - The official twitter account of the Federal Aviation Administration tweeted: "Southwest Airlines requested the FAA pause the airline's departures. Please contact Southwest Airlines for more." Southwest Airlines has been responding to tweets from its own customer service accounts and referring to "intermittent technology issues." Reference Link
LUV

Hot Stocks

10:38 EDT 'Intermittent technology issues' interrupts Southwest's operations - In response to a Twitter user complaining of a "nationwide grounding," a representative for Southwest said, "As a result of the intermittent technology issues that we experienced, we should hopefully be resuming our operation as soon as possible. We apologize for any inconvenience this may cause, but we're hoping to get everyone going ASAP. -Jeni" Reference Link
GXO

Hot Stocks

10:25 EDT GXO Logistics expands partnership with Vivienne Westwood - GXO Logistics is extending and expanding its partnership with international fashion and luxury goods company Vivienne Westwood in a 9,500-square-meter solution at its shared services site in Carisio, Italy. GXO's support for Vivienne Westwood includes value-added services such as reconditioning, quality control, labelling, packing, gift boxing and re-labeling.
RPTX

Hot Stocks

10:23 EDT Repare Therapeutics presents initial data from Phase 1/2 TRESR, ATTACC trials - Repare Therapeutics presented initial data from its ongoing Phase 1/2 TRESR clinical trial evaluating camonsertib, a potent and selective oral small molecule inhibitor of ATR, in combination with a poly polymerase inhibitor, talazoparib, and initial data from its ongoing Phase 1b/2 ATTACC clinical trial, evaluating camonsertib in combination with two additional PARPis, niraparib or olaparib, in patients with advanced solid tumors. The data involving novel combinations of low doses of camonsertib and three different PARPis are featured today at the 2023 AACR Annual Meeting in a clinical plenary session titled, "Safety and efficacy of three PARP inhibitors combined with the ataxia telangiectasia- and Rad3-related kinase inhibitor camonsertib in patients with solid tumors harboring DNA damage response alterations". This study population comprised patients with a broad range of historically difficult to treat tumors, including patients with platinum-resistant tumors, patients who had either recurred or progressed during or after treatment with PARPis, and patients who had developed known BRCA-reversion mutations. Key Initial Findings from the TRESR Phase 1/2 and ATTACC 1b/2 PARPi Combination Studies: TRESR is a first-in-human, multi-center, open-label Phase 1/2 dose-escalation and expansion study, designed to establish the recommended Phase 2 dose and schedule, evaluate safety and pharmacokinetics and identify preliminary anti-tumor activity associated with camonsertib, given alone and in combination with talazoparib or in combination with gemcitabine. ATTACC is a first-in-human, multi-center, open-label Phase 1b/2 dose-escalation and expansion study, designed to evaluate safety and pharmacokinetics and identify preliminary anti-tumor activity associated with camonsertib in combination with niraparib or olaparib. The clinical plenary session described initial combination Phase 1/2 results from 107 patients, of which 90 patients were evaluable for efficacy treated at least 13 weeks prior to the data cutoff of February 27, 2023. Key highlights from the data presented at the 2023 AACR Annual Meeting include: Camonsertib combination resulted in durable clinical benefit across tumor types and different genomic alterations, regardless of choice of PARPi and presence of platinum resistance. Overall clinical benefit rate for all patients was 48%. Patients with platinum-resistant tumors had an overall response rate of 12% and CBR of 49%, and benefited similarly to non-platinum-resistant tumors. Compelling results were observed particularly in patients with advanced ovarian cancer. In these patients, overall response was 32%, CBR was 58% and median progression-free survival was approximately 7 months with treatment greater than16 weeks and ongoing in 9 patients. Early ctDNA molecular responses in 66% of evaluable patients confirms antitumor activity of low dose, intermittent PARPi + ATRi therapy. The molecular response rate was significantly higher in patients with clinical benefit compared to those without, confirming treatment effect. Molecular responses were observed in patients with prior PARPi exposure and platinum resistance. Camonsertib combinations appear to be well tolerated. Dose limiting toxicity in 68 patients treated with the proposed combination doses were related to myelotoxicity only. No prophylactic growth factors were required when administering the PARPis at evaluated doses.
AIRS

Hot Stocks

10:05 EDT AirSculpt slips as Storm King says financial prospects 'decidedly ugly' - In a recently published short report, Storm King Reports says that an "investigation reveals another side to AirSculpt's business equation that doesn't make it into these photo galleries. For a significant population of AirSculpt's clients, its claims of pain-free body transformation do not hold up... Patient dissatisfaction is hardly the company's only problem." Further, Storm King claims that "AirSculpt's own financial prospects are decidedly ugly. And while its income statement is splattered with red ink, the company has much bigger problems than profitability on its immediate horizon. That's because a small group of insiders, according to company filings, were able to execute a series of transactions that provided them over 95 percent of the money the company raised just before and after its initial public offering. AirSculpt's financial flexibility has been greatly reduced." Shares of AirSculpt have dropped about 2% to $4.95 in Tuesday morning trading. Reference Link
PHIO

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10:00 EDT Phio Pharmaceuticals Corp trading resumes
PLOW

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10:00 EDT Douglas Dynamics falls -5.2% - Douglas Dynamics is down -5.2%, or -$1.54 to $28.29.
SJT

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10:00 EDT San Juan Basin Royalty Trust falls -6.4% - San Juan Basin Royalty Trust is down -6.4%, or -66c to $9.71.
IH

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10:00 EDT iHuman falls -8.8% - iHuman is down -8.8%, or -30c to $3.09.
AVIV

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10:00 EDT Aviv REIT rises 5.3% - Aviv REIT is up 5.3%, or $2.62 to $52.03.
ITCB

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10:00 EDT Itau Corpbanca rises 5.8% - Itau Corpbanca is up 5.8%, or 20c to $3.59.
SBSW

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10:00 EDT Sibanye Stillwater rises 9.4% - Sibanye Stillwater is up 9.4%, or 81c to $9.41.
GS

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09:52 EDT Goldman Sachs sees pace of fundraising slowing for rest of year
PHIO

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09:50 EDT Phio Pharmaceuticals Corp trading halted, volatility trading pause
TMUS

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09:47 EDT Clevon chooses T-Mobile as preferred connectivity provider for robot fleet - Clevon named T-Mobile as the preferred connectivity provider for its fleet of Autonomous Robot Carrier in the United States. Under the long-term deal, T-Mobile will provide IoT solutions for Clevon's latest ARC - the all-electric, multifunctional CLEVON 1. Clevon will rely on T-Mobile's award-winning network and IoT solutions to help power reliable, safe and efficient fleet operations for on-demand driverless delivery services.
CLB

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09:47 EDT Core Laboratories falls -4.1% - Core Laboratories is down -4.1%, or -92c to $21.39.
AQN

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09:47 EDT Algonquin Power falls -4.8% - Algonquin Power is down -4.8%, or -41c to $8.09.
IH

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09:47 EDT iHuman falls -7.1% - iHuman is down -7.1%, or -24c to $3.15.
ITCB

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09:47 EDT Itau Corpbanca rises 5.5% - Itau Corpbanca is up 5.5%, or 19c to $3.58.
HRTG

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09:47 EDT Heritage Insurance rises 6.9% - Heritage Insurance is up 6.9%, or 21c to $3.27.
SBSW

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09:47 EDT Sibanye Stillwater rises 8.5% - Sibanye Stillwater is up 8.5%, or 73c to $9.34.
GS

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09:46 EDT Goldman Sachs sees moderating repurchase levels in Q2 vs. Q1
NBIO

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09:45 EDT Nascent Biotech submits Phase 2 clinical research protocol to FDA - Nascent Biotech announced that the Protocol for the Phase 2 clinical trials was submitted to the FDA for review and approval. The review is required for approval to commence the next phase in the development of Pritumumab. Data related to Phase 1 Clinical Research evaluating safety and tolerance for PTB as a treatment for Primary and Metastatic Brain Cancers has also been submitted to the FDA. The Company anticipates initial comments from the FDA approximately 30 days from the date of filing.
GS AAPL

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09:44 EDT Goldman Sachs 'excited' to deepen partnership with Apple
CMCXF

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09:43 EDT CMC Metals announces drill results at Silver Hart, Yukon - CMC Metals announces results from its drill program conducted at its flagship Silver Hart Project in the 2022 exploration season. Approximately 4,404 meters of diamond drilling was completed in 25 holes. Highlights include; Hole SHM22_06 intersected 813 g/t AgEq over 8.25 meters, including a 0.60 meter intersection of 2,827 g/t silver, 18.7% zinc, and 1.6% lead. The drill program tested five areas of the property including; An extension of the KL vein - Main Zone; An area of the carbonate belt proximal to the Main Zone veins; The St. Patrick Vein; T1 Conductor; and The T4 Conductor.John Bossio, Chair noted, "It is evident that mineralization at Silver Hart is not limited to the vein system and the potential to find significant skarn-related and/or carbonate replacement style deposits still exists. The Board feels it is now important to conduct a review of over 15 years of exploration at Silver Hart in order to gain a better understanding of the mineralizing system that will aid in pinpointing new targets outside of the vein systems."
MRNA...

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09:42 EDT FDA clears second bivalent COVID booster for older individuals - The Food and Drug Administration today amended the emergency use authorizations of the Moderna (MRNA) and Pfizer (PFE) - BioNTech (BNTX) COVID-19 bivalent mRNA vaccines to "simplify the vaccination schedule for most individuals." The action includes authorizing the current bivalent vaccines to be used for all doses administered to individuals six months of age and older, including for an additional dose or doses for certain populations. The monovalent Moderna and Pfizer-BioNTech COVID-19 vaccines are no longer authorized for use in the United States. Most individuals, depending on age, previously vaccinated with a monovalent COVID-19 vaccine who have not yet received a dose of a bivalent vaccine may receive a single dose of a bivalent vaccine. Most individuals who have already received a single dose of the bivalent vaccine are not currently eligible for another dose. Individuals 65 years of age and older who have received a single dose of a bivalent vaccine may receive one additional dose at least four months following their initial bivalent dose, the FDA said in a statement. Reference Link
RLAY

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09:40 EDT Relay Therapeutics trading halted, news pending
GS GSKY

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09:38 EDT Goldman Sachs exploring sale of GreenSky
GS

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09:38 EDT Goldman Sachs 'well prepared' if environment weakens further, says CEO
GS GSKY

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09:37 EDT Goldman Sachs: GreenSky 'a good business,' 'may not be best holder long-term'
WINT

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09:35 EDT Windtree Therapeutics Inc trading resumes
GS

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09:34 EDT Goldman Sachs CEO Solomon: Worst of volatility appears 'behind us' - Comments taken from Q1 earnings conference call.
ADAG

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09:31 EDT Adagene presents clinical data for anti-CTLA-4 SAFEbody ADG126 - Adagene announced interim results from its combination dose escalation studies of the masked, anti-CTLA-4 SAFEbody, ADG126, presented at the AACR Annual Meeting in Orlando, Florida, April 14-19, 2023. Two poster presentations on ADG126 SAFEbody reported results of ongoing phase 1b/2 trials at multiple dosing regimens in combination with either pembrolizumab or toripalimab, as well as updated data for ADG126 monotherapy in heavily pre-treated patients. Key findings include: Best-in-class Safety Profile Reinforced in Combination with Anti-PD-1: In dose escalation studies of ADG126 in combination with anti-PD-1 treatments, ADG126 continues to demonstrate a best-in-class safety profile at doses from 6 mg/kg up to 10 mg/kg. The combination was well tolerated with no dose-limiting toxicities observed with repeat cycles, including in patients who received four or more cycles in the combination cohort with toripalimab. Confirmed Clinical Responses & Tumor Shrinkage in Combination with Anti-PD-1: In the heavily pre-treated patient groups, clinical responses and tumor shrinkage were observed during combination dose escalation. Compelling Monotherapy Safety Profile with Prolonged Stable Disease Supports ADG126 Mechanism: An additional cohort of 30 patients who received ADG126 monotherapy showed a compelling safety profile for ADG126, with no Grade 3 or higher TRAEs reported at repeat doses up to 20 mg/kg. Across all dose levels, the disease control rate was 37% among 27 evaluable patients. Prolonged stable disease was observed in five patients, with notable tumor shrinkage observed in an ovarian cancer patient who received 25 cycles at 1 mg/kg and a non-small cell lung cancer patient who received 14 cycles at 20 mg/kg. Analysis of a clinical sample from a hepatocellular carcinoma patient previously treated with atezolizumab and bevacizumab demonstrated Treg depletion, supporting the mechanism of action for ADG126. Combination Dose Expansion Ongoing in MSS CRC: Dose expansion cohorts are currently underway evaluating ADG126 in combination with anti-PD-1 therapy with an update planned later in 2023. The cohorts evaluate disease control rate, progression free survival, overall survival and objective response rate. Multiple dosing schedules are being evaluated, including ADG126 10 mg/kg every three and six weeks.
WINT

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09:30 EDT Windtree Therapeutics Inc trading halted, volatility trading pause
EDBL

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09:28 EDT Edible Garden provides update on ongoing initiatives - Edible Garden AG provided an update on ongoing initiatives the Company has taken to establish its leadership and reinforce its commitment to food safety. Jim Kras, Chief Executive Officer of Edible Garden, commented, "Consumers demand food that is not only nutritious and sustainably produced but, most importantly, safe to consume. Recent produce recalls have only reinforced these concerns. While no company is immune to potential risks, Edible Garden has consistently positioned itself at the forefront of the industry. Embodying our 'Simply Local...Simply Fresh' mission, we pledge to deliver products cultivated using the safest standards and most energy-efficient technologies available. We uphold protocols throughout the growing, harvesting, and packaging processes within our clean, controlled, indoor environment to ensure our produce consistently meets standards. In line with this commitment, Edible Garden actively engages with The Global Food Safety Initiative, an industry-driven initiative providing thought leadership and guidance on essential food safety management systems to maintain safety across the supply chain. This cooperative effort brings together the world's leading food safety experts from diverse sectors, including retail, manufacturing, food service, international organizations, governments, academia, and service providers catering to the global food industry."
GMVD

Hot Stocks

09:28 EDT G Medical says patient enrollment grows home monitoring services 194% - G Medical Innovations reports that patient enrollment has grown in its home monitoring services by 194% between January and April of 2023, as compared to the same period last year. The increase is due to growing demand for homecare monitoring. As previously announced, in the first quarter of 2023, G Medical signed an agreement with AdventHealth of Central Florida, an operator of 20 hospitals and emergency rooms. AdventHealth experiences on average 5.7 million patient visits per year. G Medical also recently signed an agreement with MiCare Path to integrate MiCare Path's software platform and visualization tools to its devices. By integrating MiCare Path's virtual health solutions with G Medical's global health solutions and devices, physicians and patients will benefit from the next-generation care driving better outcomes for patients across all services. The G Medical collaboration will allow for a total remote patient monitoring and remote therapeutic monitoring solution from service to exceptional future solutions. The Company looks forward to announcing additional key agreements in 2023. In line with its strategy of providing remote health services, in the second half of 2022, G Medical entered the at home laboratory testing market by developing 31 test kits for use by consumers at its CLIA-certified laboratory in Austin, Texas, which is now fully operational. G Medical expects that in the third quarter of 2023 consumers will be able to purchase these kits at retail stores or via online purchase. From the comfort and privacy of their own home, consumers will be able to use its kits to collect their own saliva, urine or blood sample and send it by mail to its lab in Austin for testing and analysis and receive complete report within 48 hours.
IMRX

Hot Stocks

09:27 EDT Immuneering down 5% at $11.53 after pricing $30M stock offering
JNJ

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09:27 EDT Johnson & Johnson says procedures trending above pre-Covid levels - Expects more stability through balance of year.
PRGS

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09:25 EDT P.F. Chang to transform digital presence with Progress Sitefinity - Progress announced that P.F. Chang's has transformed its digital presence with Progress Sitefinity, dramatically improving site speed and providing exceptional usability for its customers. The company said, "As the digital world continues to evolve, P.F. Chang's saw an opportunity to upgrade its website design and supporting technologies and ensure its digital presence supports the needs of the modern consumer. Additionally, P.F. Chang's is deeply committed to providing exceptional usability, with strict adherence to Web Content Accessibility Guidelines Level AA and accommodating users of all types as consistent with the American Disabilities Act."
AGBA

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09:25 EDT AGBA Acquisition announces 1M share repurchase program - AGBA Group announced that its Board of Directors approved a share repurchase program with authorization to purchase up to 1,000,000 ordinary shares of AGBA with a maximum of $10,000,000 to be expended. The share repurchase program reflects AGBA's commitment to returning value to its shareholders, while maintaining the financial flexibility to invest in growth opportunities. The program also reflects the company's confidence in its future prospects.
IVDA

Hot Stocks

09:24 EDT Iveda Solutions partners with Evergreen Aviation - Iveda announces a partnership with aircraft maintenance solutions provider, Evergreen Aviation Technologies to bring cutting-edge Unmanned Aerial Vehicles to the global market. Through this collaboration, Iveda will also gain worldwide rights to promote and sell military grade drones that can fly at 10,000 to 30,000 feet, vastly expanding EGAT's reach cross-border. Leveraging each company's technological developments, Iveda and EGAT together will provide governments and military groups around the world access to state-of-the-art smart drones, effectively enhancing surveillance capabilities. Through this joint operation, EGAT will provide Iveda with the assets, technical support, and training to facilitate the promotion and sale of its UAV products on a global scale, especially important as Fortune Business Insights predicts the UAV drone market to reach $25.13B by 2027. Together, EGAT and Iveda will explore the development of smart drone features, including Iveda's AI Video Analytic and sensor technologies. Powered by AI technology, smart drones can send real-time alerts and detections to those monitoring for risks -- not just after the fact analysis. IvedaAI allows in-the-moment detection, allowing government and military officials to greatly speed up response times. Iveda-powered UAVs can monitor an expansive stretch of land in real time, making them critical, next-generation tools for military groups including coast guards. Providing visibility far beyond human sight, smart drones have the potential to prevent major security breaches, arming military and government associations around the globe with the technology needed to keep citizens safe.
LPLA

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09:23 EDT CG Advisor Network selects LPL Financial as custodian, broker-dealer - LPL Financial announced that CG Advisor Network, an entity of the RIA CG Advisory Services, has selected LPL as its primary custodian and exclusive broker-dealer. They reported having served approximately $3.1 billion in advisory and brokerage assets, previously at TD Ameritrade and Geneos Wealth Management.
JOAN

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09:21 EDT Joann CFO buys $44K in common stock - In a regulatory filing, Joann disclosed that its CFO Scott Sekella bought 27.7K shares of common stock on April 14th in a total transaction size of $44K. Shares of Joann are up about 4% in pre-market trading at $1.62.
ASTI

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09:21 EDT Ascent Solar completes transaction to acquire manufacturing assets of Filsom - Ascent Solar Technologies announced that it has completed a transaction to acquire the Zurich-based manufacturing assets of thin-film solar manufacturer, Flisom AG. The Company will continue to be headquartered in Thornton, CO and will commence manufacturing using its new 15MW roll-to-roll thin-film manufacturing assets in Zurich, CH immediately. "Since coming aboard the Company in September 2022, my priority has been to execute an aggressive turnaround plan and to re-establish Ascent as the leading provider of high-performance, flexible thin-film solar modules for use in scenarios where traditional rigid panels don't work," said Jeffrey Max, President and Chief Executive Officer of ASTI. "This transaction is an ignition point for our continued turnaround, by opening new markets, securing new revenue, and expanding manufacturing capabilities to set Ascent on a new trajectory."
TENB

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09:20 EDT Tenable Holdings announces enhancements to Technology Ecosystem Program - Tenable announced significant enhancements to its Technology Ecosystem Program, driven by a shift toward exposure management solutions. The program has also expanded to include integrations with its innovative operational technology security solution, Tenable OT Security.
ERAS

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09:19 EDT Erasca presents Phase 1b dose escalation data from FLAGSHIP-1 for ERAS-601 - Erasca presented promising initial Phase 1b dose escalation data from FLAGSHP-1 for ERAS-601 in combination with cetuximab in patients with advanced solid tumors as part of a poster presentation at the American Association for Cancer Research, AACR, Annual Meeting in Orlando, Florida. ERAS-601 is a potent, selective, oral small molecule SHP2 inhibitor with best-in-class potential. The poster is available online at Erasca.com/science/presentations. Preliminary dose escalation results of ERAS-601 in combination with cetuximab in FLAGSHP-1: A Phase I study of ERAS-601, a potent and selective SHP2 inhibitor, in patients with previously treated advanced or metastatic solid tumors. ERAS-601 in combination with cetuximab inhibits RAS/MAPK signaling at multiple nodes which is predicted to limit the development of treatment resistance and offer more robust synergistic anti-tumor activity over monotherapy alone. ERAS-601 in combination with cetuximab shows promising preliminary safety and tolerability with reversible and manageable treatment-related adverse events; Only grade 1 or 2 TRAEs occurred at or below the combination MTD for ERAS-601; ERAS-601 MTD was determined to be 40 mg BID 3/1 in combination with cetuximab administered every 2 weeks; Initial Phase 1b dose expansion data in HPV-negative HNSCC tumors is expected in H1 2024
PBIO

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09:19 EDT Pressure BioSciences, Artisan Industries enter strategic agreement - Pressure BioSciences and Artisan Industries announced a strategic agreement between the companies. The agreement focuses on two highly important areas: PBIO will rent space and ancillary support in Artisan's state-of-the-art facilities, which will dramatically increase PBIO's manufacturing capacity for servicing the needs of its growing portfolio of Ultra Shear Technology-based nanoemulsion clients; and the relationship is expected to facilitate discussions between the companies towards an agreement that would secure Artisan as the exclusive manufacturer of PBIO's revolutionary UltraShear equipment. PBIO will continue to accept contracts for toll processing of customer's nanoemulsions requirements for the foreseeable future. Beginning in 2024, PBI's business plan will add a lease and license model, whereby the Company will be placing UltraShear equipment in the hands of customers at the cost of a monthly lease payment plus a toll/royalty rate on the output of the UST equipment. Under this growth strategy, the Company believes it may need hundreds or thousands of instruments over the coming years. The UST System contains a number of unique and complex designs and components; Artisan has an impressive history of innovation, professional manufacturing, and quality management - making them a natural and ideal choice for a prospective equipment building contract.
NVEI

Hot Stocks

09:17 EDT Nuvei sinks 8% to $38.90 after Spruce Point short report
MGRX

Hot Stocks

09:17 EDT Mangoceuticals debut commercial surpasses 5M views on YouTube - Mangoceuticals is pleased to announce that its commercial, which originally debuted on YouTube in November 2022, has surpassed over 5 million views.
THTX

Hot Stocks

09:17 EDT Theratechnologies presents new data at AACR annual meeting - Theratechnologies presented preclinical data that demonstrate the potential utility of its lead investigational peptide drug conjugate, PDC, candidate, sudocetaxel zendusortide, TH1902 -- both as a single agent and in combination with other anticancer therapies -- in targeting tumors that express the sortilin, SORT1, receptor. The new data were presented in poster sessions at the 2023 annual meeting of the American Association for Cancer Research, AACR, in Orlando, Fla. In two separate posters presented at AACR, sudocetaxel zendusortide demonstrated increased anti-cancer efficacy in combination with programmed cell death-ligand 1 checkpoint inhibitor therapy in a melanoma mouse model; and as a single agent against SORT1-positive TNBC or HER2+ breast cancer models, resulting in complete tumor regression. Furthermore, sudocetaxel zendusortide generated superior activity in comparison to a combination of Herceptin and docetaxel in the HER2+ Herceptin-resistant tumor model. A third poster showed high expression of SORT1 in multiple tumor types, compared to healthy tissues, bolstering the rationale for SORT1 inhibition as a potential therapeutic approach. "It's particularly exciting to see in the melanoma animal model that using the SORT1 receptor with sudocetaxel zendusortide in combination with immunotherapy shows greater tumor inhibition and longer survival compared to immunotherapy alone," said Christian Marsolais, Ph.D., Senior Vice President and Chief Medical Officer of Theratechnologies. "Collectively our three AACR poster presentations reinforce the potential of sudocetaxel zendusortide, on its own and in combination, to enable targeted delivery of anticancer therapy. We look forward to further characterizing this novel investigational agent as we seek partners and advance our clinical development program."
FAT

Hot Stocks

09:16 EDT Fat Brands announces Johnny Rockets at Kempegowda International Airport - FAT Brands announces a new location in India at the Kempegowda International Airport in partnership with HMSHost. Located in Bengaluru, the capital city of Karnataka, the new Johnny Rockets serves the classic fare that put the brand on the map over 35 years ago, including juicy, made-to-order burgers and hand-spun shakes.
VMD

Hot Stocks

09:15 EDT Viemed Healthcare enters definitive agreement to acquire HMP - Viemed Healthcare announced that it has entered into a definitive agreement to acquire Tennessee based Home Medical Products, HMP, a large regional provider of respiratory focused home medical solutions. "We are incredibly excited to complement our strong history of organic growth by combining great teams through accretive transactions" said Viemed Chief Executive Officer Casey Hoyt. "The purchase of HMP will launch our acquisition growth initiatives with a stellar organization that has an extraordinary reputation with patients, payors, and physicians. Above all, the team at HMP shares our same driving passion for innovative patient-focused care."
YMAB

Hot Stocks

09:14 EDT Y-mAbs Therapeutics announces presentation of naxitamab data at AACR - Y-mAbs Therapeutics announced that a poster presentation featuring preclinical data on naxitamab, a recombinant, humanized anti-GD2 monoclonal antibody will be presented at the AACR Annual Meeting 2023, which takes place in Orlando, Florida from April 14-19, 2023. The poster, "Investigational novel humanized anti-GD2 antibody inhibits GD2-mediated immunosuppression by targeting GD2+ breast cancer stem-like cells," will be presented on April 18, 2023, from 1:30 to 5:00 pm EST. The disialoganglioside GD2 has been shown to be upregulated in triple-negative breast cancer and its high expression is associated with a poor prognosis. Furthermore, breast cancer stem-like cells are reported to be a major contributing factor for metastatic spread of TNBC and contribute to chemotherapy resistance, making them an important target for therapeutic intervention. Currently, there are no available therapeutic tools for targeting BCSCs. New preclinical data from M.D. Anderson Cancer Center demonstrate that TNBC with high GD2 expression inhibits immune cell infiltration and that naxitamab targets GD2+ BCSCs and may be able to inhibit the growth of BCSCs by enhancing macrophage-mediated phagocytosis, NK cell-mediated ADCC, and T cell-mediated cytotoxicity.
GTLB ORCL

Hot Stocks

09:13 EDT GitLab, Oracle expand strategic collaboration - GitLab, and Oracle Corporation announced the general availability of a new offering that expands shared artificial intelligence and machine learning functionalities. Customers can now run AI and ML workloads with GPU-enabled GitLab runners on Oracle Cloud Infrastructure. GitLab strives to meet customers where they are, and this collaboration with OCI provides streamlined access to GitLab runners for Oracle users. Customers benefit from OCI's high performance, built-in security, and distributed cloud capabilities, giving them the flexibility to access and deploy cloud services wherever they need them, including on-premises and multicloud environments.
DH SNOW

Hot Stocks

09:12 EDT Definitive Healthcare brings healthcare intelligence to Snowflake Marketplace - Definitive Healthcare (DH) announced the launch of its Atlas Dataset on Snowflake Marketplace (SNOW). Joint customers can now access and connect Definitive Healthcare's Atlas Dataset, enabling them to make better, more informed decisions about their commercialization efforts. "We're excited to bring our Atlas Dataset to the Snowflake Data Cloud," said Robert Musslewhite, CEO of Definitive Healthcare. "Now, joint customers of Definitive Healthcare and Snowflake can seamlessly integrate large amounts of our proprietary healthcare commercial intelligence into their existing workflow to better understand, compete, and win in the complex healthcare market."
FTNT

Hot Stocks

09:12 EDT Fortinet joins Joint Cyber Defense Collaborative - Fortinet announced it has become a member of the Joint Cyber Defense Collaborative, furthering the company's commitment to strengthening the United States' security posture and cybersecurity resilience. The Cybersecurity and Infrastructure Security Agency established JCDC in 2021 to bring together public and private entities with the goal to gather, analyze and share actionable information to more proactively protect and defend against cyber threats. These types of collaborative efforts help build systemic resilience by both coordinating incident response and by addressing vulnerabilities and other cyber risks before they are exploited.
DH

Hot Stocks

09:11 EDT Definitive Healthcare announces DefinitiveConnect on Salesforce AppExchange - Definitive Healthcare announced it has launched DefinitiveConnect on Salesforce AppExchange, empowering customers to save time, build new opportunities, and drive revenue with Definitive Healthcare's commercial intelligence directly in Salesforce. DefinitiveConnect enables users to integrate key healthcare insights directly with Salesforce. With DefinitiveConnect, customers can import more than 300 data elements directly into an Account, Contact, or Lead record in Salesforce so customers can quickly access meaningful intelligence around facility metrics, key executives, and organizational news all in one place. "DefinitiveConnect helps our customers seamlessly access Definitive Healthcare data directly in Salesforce, without leaving their existing workflow," said Robert Musslewhite, CEO of Definitive Healthcare. "The combination of our healthcare commercial intelligence with Salesforce helps our joint customers make more informed and data-driven decisions around their commercial strategy and execution."
VZ

Hot Stocks

09:11 EDT Verizon Business, Cleveland Clinic to explore use of 5G network - Verizon Business announced the deployment of a private 5G network at the new Cleveland Clinic hospital in Mentor, Ohio. Through this collaboration the two companies will develop ways to utilize this technology to enhance patient care, provide caregivers with greater connectivity to deliver that care and elevate the patient and visitor experience.
JNJ

Hot Stocks

09:10 EDT Johnson & Johnson does not see material sales of Covid-19 vaccine after Q1 - Feels "very good" about product pipeline. Says remains "vigilant" regarding M&A, but will not due anything "out of desperation."
SVFD

Hot Stocks

09:10 EDT Save Foods CEO releases letter to stockholders - Save Foods published a letter to its stockholders from David Palach, CEO of Save Foods: " I am pleased to announce that Save Foods has entered into a partnership with Plantify Foods. This partnership represents a significant milestone for us and underscores our commitment to providing innovative and sustainable food solutions to customers around the world. To establish this partnership, we issued 1,164,374 shares of Save Foods' common stock and received in exchange 30,004,349 of Plantify's common shares, equivalent to 19.99% of Plantify's share capital. Additionally, Save Foods and Plantify executed an 18-month convertible debenture, whereby Save Foods extended a C$1,500,000 loan to Plantify, which will accrue interest at a rate of 8% annually. The debenture may be converted into common shares of Plantify at a price of C$0.05 per share until the first anniversary of the debenture issuance date and C$0.10 per share thereafter... In my previous letter I mentioned that we were looking for collaborative opportunities and I believe that Plantify is the perfect match for us. Plantify has already established direct relationships and sales channels with retailers globally, including KAYCO, a leading kosher food distributor in North America under Heaven & Earth brand, which presents a tremendous opportunity for Save Foods. Through this partnership, we will be able to offer our premium treatments, designed specifically for fresh cuts and berries, to Plantify's products, reaching a wider customer base and expanding our sales opportunities."
DTE

Hot Stocks

09:10 EDT DTE Energy announces commissioning of Meridian Wind - DTE Energy announced that Michigan's largest wind park, Meridian Wind, is now operational. Spanning three townships across Midland and Saginaw counties, the 225-megawatt wind park has 77 wind turbines and generates enough clean energy to power more than 78,000 homes. DTE managed all aspects of the Park's development, from land acquisition and permitting through construction, and will assume responsibility for the project's ongoing operations and maintenance. Meridian Wind Park is DTE's first self-developed renewable energy project since the development of Pinnebog Wind in 2016. With the commissioning of Meridian Wind Park, DTE now has 20 wind parks in its renewable energy portfolio. These projects, along with the company's 33 solar parks, generate enough clean energy to power more than 750,000 homes and represent an investment of more than $3 billion. DTE plans to add approximately 1,000 megawatts of new renewable energy each year starting in 2025, and as part of its CleanVision Integrated Resource Plan filed last fall, the company proposed adding an additional 15,000 megawatts of clean energy by 2042, giving DTE enough clean energy to power more than 4 million homes.
AUVI

Hot Stocks

09:09 EDT Applied UV says wrote down part of COVID-19 investment, completes milestones - Applied UV announces shareholder letter. "I am writing to inform all of our shareholders of the Company's accomplishments throughout 2022 and provide, to the extent possible, insights into our focus for 2023. We acquired Scientific Air late in 2021 with a mobile disinfection product suite that was client centric to one industry and distributor specific to COVID-19. Unfortunately, previous senior executive management's focus did not timely re-position the Company to address this, a mistake which we corrected. Consequentially, we determined to write down a substantial portion of our investment and put it behind us. In addition, the Company has incurred significant one-time integration and acquisition related costs associated with the more successful acquisitions, thereby exiting 2022 with a Company better positioned to achieve improved results in 2023.Despite the global supply chain disruptions borne out of the COVID pandemic and the geo-political uncertainty caused by the Ukraine war that triggered an economic slowdown throughout Europe and the world for much of 2022, the company completed significant positive milestones that, in my opinion, are not being recognized in our valuation. Despite these disruptions, the steady stewardship put forth by our entire team and board, and what we have accomplished since the completion of our Initial Public Offering almost 28 months ago, has positioned the Company for continued accelerated growth in revenue and future profitability both organically and via accretive acquisitions...We strengthened the team with the recent addition of Messrs. Brian Stern and Lawrence Webb, both staying on as presidents of the PURO and LED divisions respectively. Brian Stern has also been appointed as a director, further strengthening our board," wrote Max Munn, CEO. Chief Executive Officer, President and Director
CSSE DG

Hot Stocks

09:09 EDT Chicken Soup for the Soul signs expanded partnership with Dollar General - Redbox, a Chicken Soup (CSSE) for the Soul company, announced it signed an expanded partnership agreement with Dollar General (DG) to add 1,500 Redbox kiosks over the next two years. This will bring the number of Redbox kiosks at Dollar General to over 5,000 locations by the end of 2024, giving customers faster access to the newest movies.
VZ

Hot Stocks

09:08 EDT Verizon expands high-speed internet across Maryland - Verizon announces it is bringing more choice for internet to Maryland residents as it deploys high-speed, fiber optic broadband internet service across the state. Nearly 4,000 new households and businesses in Charles, Garrett, Cecil, Howard, St. Mary's and Washington County will have access to Verizon's Fios network. "Verizon is focused on delivering high-speed internet service and the major economic benefits that it can provide, especially in unserved and underserved areas," said Kwame Trotman, Vice President of Wireline Network Operations-Mid-Atlantic South Region for Verizon. "More people than ever across Maryland will have access to our 100% fiber Fios internet service to fuel how they work, live and play."
AVGO

Hot Stocks

09:08 EDT Broadcom announces delivery of Jericho3-AI - Broadcom announced that it has delivered Jericho3-AI, enabling the industry's highest performance fabric for artificial intelligence networks. Jericho3-AI revolutionizes AI networking with best-in-class capabilities such as perfect load balancing, congestion-free operation, ultra-high radix, and Zero-Impact Failover, all culminating in significantly shorter job completion times for any AI workload.
ALPP

Hot Stocks

09:07 EDT Alpine 4 Holdings' RCA Commercial, Elecjet enter transfer agreements - Alpine 4 Holdings announced that its subsidiaries, RCA Commercial and Elecjet, have entered into Material Transfer Agreements with US based OEMs from sectors including the RV industry, Electric Tractors, in addition to Energy Storage Systems / Powerwalls. These MTAs are the culmination of months of discussions with these OEMs and their electrification needs. The Company anticipates that as the OEMs conduct their own internal testing procedures on the AX class of batteries, this will lead to long-term market contracts for the AX Class of power cells. The overall market size of these industries exceeds $10 Billion in market opportunity for the Company.
IMRX

Hot Stocks

09:06 EDT Immuneering announces initial Phase 1 PK, PD, safety data for IMM-1-104 - Immuneering announced positive initial pharmacokinetic, PK, pharmacodynamic, PD, and safety data from the Phase 1 trial of IMM-1-104, which are being shared today in a poster presentation titled "Humanized 3D tumor models that are mutationally aligned with AACR GENIE patients predict IMM-1-104 activity in RAS-addicted tumors" at the American Association for Cancer Research, AACR, annual meeting. "We are very pleased to share initial PK, PD and safety data from our Phase 1 trial of IMM-1-104 in patients with advanced RAS mutant solid tumors, ahead of schedule," said Ben Zeskind, Ph.D., MBA, Co-founder, and Chief Executive Officer of Immuneering. "We believe these data from the first patients dosed in our study demonstrate the PK, PD and safety profile necessary for deep cyclic inhibition - the proprietary and novel mechanism through which our therapies are designed to selectively impact cancer cells to a greater extent than healthy cells, regardless of the specific RAS mutation driving the tumor. The data show that we were able to reach significant levels of PK Cmax with the aim of breaking tumor addiction to the MAPK pathway, then rapidly clearing out drug with IMM-1-104's short half-life. These results position us to accelerate the dose escalation portion of our study, reaching potentially therapeutic levels of IMM-1-104 earlier than previously planned." The Phase 1/2a clinical trial is an open-label study designed to evaluate the safety, tolerability, PK and preliminary efficacy of IMM-1-104 in patients with advanced RAS mutant solid tumors. The Phase 1 portion of the study, which is being conducted at five clinical sites in the United States, is evaluating IMM-1-104 following a Bayesian mTPI-2 escalation design, which includes a dose escalation phase and dose evaluation phase to establish an optimized RP2D candidate. Following selection of the RP2D candidate, the Company expects to conduct a Phase 2a dose expansion phase to assess the safety and efficacy of IMM-1-104 at the RP2D in RAS mutated pancreatic, melanoma, lung and colorectal cancers.
BAC

Hot Stocks

09:06 EDT Bank of America sees headcount around 213,000 by end of Q2
AMD

Hot Stocks

09:06 EDT AMD joins AWS ISV Accelerate program - AMD has joined the Amazon Web Services Independent Software Vendor Accelerate Program, a co-sell program for AWS Partners - like AMD - who provide integrated solutions on AWS. The program helps AWS Partners drive new business by directly connecting participating ISVs with the AWS Sales organization.
CSLLY

Hot Stocks

09:05 EDT CSL's Hizentra syringe receives FDA approval - CSL Behring announced the FDA approved a 50mL/10gm prefilled syringe for Hizentra, Immune Globulin Subcutaneous 20% Liquid. Hizentra is the first and only immune globulin available in a ready-to-use prefilled syringe. The 50mL prefilled syringe will be available in early 2024, which will allow CSL Behring to manufacture supply to meet anticipated demand. Hizentra will continue to be available in 5mL, 10mL and 20mL prefilled syringes as well as in 5mL, 10mL, 20mL, and 50mL vials.
SCWO

Hot Stocks

09:05 EDT 374Water, Inc. demonstrates waste managment solution - Following on the heels of the first UN Water conference in 50 years, 374Water successfully demonstrated its AirSCWO supercritical water oxidation technology during SCWO week at its manufacturing partner's facility in Indiana. The event showcased the company's revolutionary waste management solution to hundreds of prospective customers, along with analysts and investors. The 3-day event, attended by over 400 guests featured a demonstration of the first commercial unit, set to be deployed in Orange County, CA, later this year; panel discussions; and plenty of time to "see the magic inside" and engage with experts on the technology. Attendees included over 200 potential customers, including several municipalities, representing over 10 countries.
APGI

Hot Stocks

09:04 EDT American Power Group reports 2023 mid-year update - Chuck Coppa, APG's CEO/CFO stated, "While we have made significant progress over the past several years to solidify APG's financial position, we continue to focus our efforts on increasing market awareness and branding of our V6000 dual fuel vehicular solution. We believe this technology is potentially the most game-changing aspect of our business, especially from a decarbonization perspective. We are currently in discussions with several of the country's largest natural gas/renewable natural gas (RNG), biodiesel and renewable diesel dispensers regarding potential co-marketing efforts whereby they would market our cost-effective dual fuel solution in addition to dedicated natural gas solutions. Discussions are also underway with two potential new vehicular dealer/installers and we are actively seeking additional companies to join our dealer/installer network. We've initiated our next round of EPA/CARB emissions testing to expand our 500+ industry-leading EPA engine family approvals. Given the lack of current natural gas/RNG options for fleets running heavy duty 15L trucks, we are focusing on newer engine platforms in the 2020 to 2022 range starting with Cummins ISX 15L high HP (450+) engine platform given it allows for a much greater market/application coverage. We are also considering a Mx13 PACCAR Class 8 high HP engine as our next new engine family platform, again given market demand. Both our 2014 Freightliner CA125 Cascadia day cab Cummins ISX 15L (450 HP) diesel engine and 2015 Freightliner CC132 Coronado sleeper cab equipped with a 505 HP Detroit Diesel DD15 diesel engine demo trucks have been in high demand with potential customers/partners. Currently, both are being evaluated by a large west coast-based fleet operator who has embraced alternative fuels, including RNG and will be running long haul as well as short haul routes which should provide the maximum overall dual fuel experience. Since October 2022, entities controlled by our Chairman, have provided us with $2.5 million of additional funding which was used to make several of our scheduled patent/technology purchase installment payments, pay off our remaining Iowa State Bank loan in January with the balance used for operations and inventory buildup to support our quotes. Our last $730,500 patent/technology installment payment is due in May and our Chairman has committed to provide those funds, if necessary, allowing us to complete the $5 million purchase of all our dual fuel patents and associated technology."
JAMF MSFT

Hot Stocks

09:04 EDT Jamf Holding expands collaboration with Microsoft, joins MISA - Jamf (JAMF) has announced that they are now a member of the Microsoft (MSFT) Intelligent Security Association, MISA. MISA is an ecosystem of independent software vendors and managed security service providers that have integrated their solutions with Microsoft security technology to help customers better defend themselves against increasingly sophisticated cyber threats. "We are thrilled to be a member of the Microsoft Intelligent Security Association and help bring security technology to customers to better defend themselves against increasingly sophisticated cyber threats," said Nick Amundsen, Strategy Senior Vice President, Jamf. "The Jamf Protect SIEM integration with Microsoft Sentinel is a powerful solution for organizations looking to gain better visibility into security events and streamline incident response."
AMPL

Hot Stocks

09:03 EDT Amplitude appoints Nathaniel Crook as next CRO - Amplitude announced the appointment of Nathaniel Crook as the company's next chief revenue officer or CRO . With over 20 years of enterprise software sales and engineering experience, Crook will lead Amplitude's sales and partner organizations globally. "Nate has extensive experience in sales and engineering at startup and enterprise-class companies, so he's an ideal fit for this next chapter of Amplitude's growth," said Amplitude President Thomas Hansen. "His track record of scaling global sales teams, selling to the world's largest companies, and partnering with developer teams to solve problems will help Amplitude unlock the power of its customer's products."
JLL

Hot Stocks

09:03 EDT JLL acquires Kensington Capital Advisors, terms not disclosed - JLL announced it has wholly acquired Kensington Capital Advisors, a North Carolina-based derivatives and structured finance advisory firm. The acquisition includes Frame Financial Systems, a technology platform that will enable JLL to offer CRE investor clients a proprietary "software with a service" debt portfolio reporting and analytics solution. KCA and Frame's 23 employees will join the Capital Markets and JLL Technologies teams, and the technology product will be offered as a SwaS solution for investor clients looking to manage their corporate real estate debt portfolios more effectively.
NUVL

Hot Stocks

09:03 EDT Nuvalent reports new preclinical data on neurological candidate NVL-655 - Nuvalent announced the presentation of new preclinical data supporting the intracranial activity NVL-655. NVL-655 is a brain-penetrant, ALK-selective tyrosine kinase inhibitor - TKI - designed to maintain activity against ALK and ALK mutations that confer resistance to currently approved therapies, and to avoid neurological adverse events and dose-limiting toxicities associated with TRK inhibition. The data result will be presented at the American Association for Cancer Research Annual Meeting 2023, April 14-19 in Orlando. Cell viability and ALK signaling assays confirmed potent in vitro activity of NVL-655 and limited sensitivity to first- and second-generation ALK TKIs. Upon treatment with NVL-655, intracranial efficacy was confirmed via MRI. NVL-655 has previously demonstrated preclinical efficacy in a cell line model of intracranial disease, as well as preclinical activity across diverse ALK resistance mutations and tumor types while maintaining strong selectivity for ALK over TRKB. NVL-655 is currently being investigated in a first-in-human Phase 1/2 clinical trial for patients with advanced ALK-positive NSCLC and other solid tumors.
CMTL

Hot Stocks

09:02 EDT Comtech names Nicole Robinson chief strategy officer - Comtech announced the appointment of space industry veteran Nicole Robinson as a chief strategy officer. With nearly two decades of leadership experience in the space industry, Robinson brings expertise and differentiated knowledge across public, private, government, and commercial space sectors. Prior to joining Comtech, Robinson served as President of Ursa Space Systems.
MACE

Hot Stocks

09:02 EDT Mace Security director Richard Barone resigns - Mace Security International announced that Mr. Richard Barone decided to resign from its Board of Directors, effective April 14, 2023. Mr. Barone, 81, returned to Mace's Board in 2022 to lead the charge on our Strategic Alternatives project. The Strategic Alternatives Project has been quite time consuming and while significant progress has been made developing these alternatives, the current economic and market environment has meant that bringing this project to conclusion will require a commitment of time which is incompatible with Mr. Barone's other commitments and work schedule at this time. Mr. Barone has offered to continue to advise the Board on any open projects for the next six months in an advisory capacity. The Board has accepted his offer.
BAC

Hot Stocks

09:01 EDT Bank of America sees Q2 expense around $400M-$500M lower than Q1 - Sees continued sequential expense declines in Q3, Q4.
JNJ

Hot Stocks

09:00 EDT Johnson & Johnson says continues to invest in R&D at 'competitive levels' - Says R&D "remains number one priority." Says capital allocation strategy "clear and remains unchanged." Says "confident" in achieving 2025 Pharmaceutical business sales targets. Expects "above market growth" in Pharmaceutical in 2023. Says "pleased" with integration of Abiomed. Comments taken from Q1 earnings conference call.
BAC

Hot Stocks

09:00 EDT Bank of America continues to expect modest loan growth
BAC

Hot Stocks

09:00 EDT Bank of America sees NII down 2% vs. Q1
LMT

Hot Stocks

08:58 EDT Lockheed Martin sees FY23 Aeronautics sales $26.5B-$26.8B - Sees FY23 Aeronautics operating profit $2.775B-$2.805B. Sees FY23 MFC sales $11.15B-$11.35B, operating profit $1.51B-$1.53B. Sees FY23 RMS sales $15.8B-$16.1B, operating profit $1.88B-$1.91B. Sees FY23 Space sales $11.55B-$11.75B, operating profit $1.09B-$1.11B. Comments taken from Q1 earnings conference call presentation slides.
QLGN

Hot Stocks

08:53 EDT Qualigen Therapeutics announces four poster presentations on QN-302 - Qualigen Therapeutics announces data from the Company's four posters regarding its' lead program, QN-302, was presented at the American Association for Cancer Research Annual Meeting 2023 held April 14-19 in Orlando, FL. Abstract #390 - "A comparison of the activity of the quadruplex-targeting experimental drugs QN-302 and CX-5461 in wild-type and gemcitabine-resistant pancreatic cancer cell lines" Ahmed Ahmed, Tariq Arshad, and Stephen Neidle - Results demonstrated that QN-302, retains potency in the two gemcitabine resistant cell lines. Up-regulated G4 genes in the resistant line are down-regulated by QN-302. The retention of QN-302 activity in chemo-resistant PDAC cell lines suggests that it may potentially offer significant advantage in the clinic over gemcitabine-based therapies. Gemcitabine either alone or in combination is still among the standard of care for current PDAC treatment. Resistance to gemcitabine is common and is a major contributor to the poor outcomes for most PDAC patients. Abstract #4981 - "The potent quadruplex-binding compound QN-302 down-regulates the S100P gene in vitro and in vivo models of pancreatic cancer: a potential therapeutic target and biomarker for PDAC" Nicole Williams, Jenny Worthington, Ahmed Ahmed, Tariq Arshad and Stephen Neidle - The poster highlighted that QN-302 showed lower expression of the S100P gene on xenograft models following dosing either twice or four times weekly with QN-302. S100P is elevated in human PDAC. Investigators posit that S100P may be a potential biomarker for QN-302 therapy as it contains a G4 in its promoter region and binds QN-302. Abstract #6240 - "The potent quadruplex-binding compound QN-302 shows anti-tumor activity as a monotherapy in an orthotopic in vivo model of pancreatic cancer" Nicole Williams, Danielle Santos, Jenny Worthington, Ahmed Ahmed, Tariq Arshad and Stephen Neidle - Study authors identify orthotopic study as the fourth in vivo pancreatic cancer model showing anticancer activity for QN-302, further confirming its potential for human cancer treatment. Abstract #3098 - "Structure-based design rules for potent quadruplex-binding compounds based on the naphthalene diimide core" Stephen Neidle - The study author concluded that the available data indicates that G4 affinity is necessary but insufficient for cellular activity. The ND core contributes little to G4 affinity. Charged side chains are important for strong G4 binding and cellular activity; greater than2 cationic side chains are required for both G4 binding and activity. Four highly cationic side chains reduce cellular activity but enhance G4 affinity - less basic morpholine groups enhance it. Molecular modeling suggests that enhancing the ND core with a planar hydrophobic group could increase G4 affinity and enhance cellular uptake. Four basic side chains, two of which are morpholino, are used to optimize the series without excess basicity. Docking QN-302 into the G4-duplex structure indicates that the phenyl substituent is well stacked on a G of the quartet, as predicted.
IVCGF

Hot Stocks

08:52 EDT Iveco Group inaugurates new plant in Foggia - IVECO BUS inaugurated its new Foggia plant dedicated to the production of zero- and low-emission buses, in front of public authorities, trade union representatives, customers, suppliers and partners. According to the industrial plan, at full speed the new facility will employ 100 highly specialised people working lines equipped with the most advanced Industry 4.0 technologies. The production volume of the plant will be 1,000 vehicles per year: high-tech buses with zero-emission propulsion and low-emission propulsion. The plant emits zero net CO2 emissions. 100% of its energy comes from renewable sources, including over 1,000 photovoltaic panels that produce 640 MWh per year. The entire project focuses on reducing energy consumption and recycling, making use of high-performance construction materials, Intelligent LED lighting and rainwater reuse. Iveco Group is already present in Foggia with its FPT Industrial plant for the production of industrial engines and 1,600 employees, which make this one the largest industrial establishments in Puglia. The investment in the new plant of approximately 40 million euros - that will be partially offset by funds from the PNRR, the National Recovery and Resilience Plan - is strategic and puts two pillars of the PNRR into practice: "Green revolution and ecological transition" and "Infrastructure for sustainable mobility".
LINC CWK

Hot Stocks

08:50 EDT Lincoln Educational retains Cushman & Wakefield as real estate services provider - Lincoln Educational Services announced that it has retained Cushman & Wakefield as its exclusive real estate services provider across the United States.
ORBT

Hot Stocks

08:48 EDT Orbit International announces delay in filing 2022 annual report - Orbit International announced that the filing of its 2022 Annual Report with the OTC has been delayed beyond its extended due date of April 17, 2023, as additional time is needed to complete the audit of the acquired and ending inventory of its recently acquired Simulator Product Solutions LLC subsidiary and the preparation of the 2022 Annual Report. Mitchell Binder, President and CEO commented, "Some additional time is needed to complete our filing as our auditors complete their audit of the acquired inventory of SPS on January 3, 2022, as well as its ending inventory at December 31, 2022. Because the acquired inventory comprised a part of the purchase price of SPS, any one-time adjustments should have no material effect on the financial statements of Orbit. Furthermore, we do not expect any adjustments to SPS' ending inventory to have any material effect on the financial statements of the Company. Based on the amount of work expected to be completed by the Company and its auditors, we anticipate filing our 2022 Annual Report in approximately two to three weeks."
AWR

Hot Stocks

08:47 EDT American States Water unit gets proposed decision from CPUC for water rates - American States Water Company announced that on April 13 its regulated water utility subsidiary, Golden State Water Company GSWC , received a proposed decision from the assigned administrative law judge at the California Public Utilities Commission CPUC in connection with the pending general rate case proceeding that will determine new water rates for the years 2022 - 2024. A final decision by the CPUC is expected during the second quarter of 2023. When a final decision is issued by the CPUC, the new rates for 2022 will be effective and retroactive to January 1, 2022. As a result, the retroactive impact for the full year of 2022 will be reflected in the 2023 first quarter results. The estimated escalation increases for 2023 will be effective as of January 1 and also reflected in the 2023 first quarter results. We are in the process of reviewing the proposed decision to finalize all of the impact to be recorded in the 2023 first quarter results that will be reported in our first quarter earnings release and Form 10-Q that will be filed with the Securities and Exchange Commission. AWR intends to release its first quarter ended March 31, 2023 financial results after the market closes on Wednesday, May 10.
PINC

Hot Stocks

08:47 EDT Premier, Monaghan Medical sign AscenDrive contract - Monaghan Medical and Premier announced their agreement to a three-year contract, effective May 1, 2023, creating a partnership between two healthcare industry leaders. Through this partnership, Monaghan will provide Premier AscenDrive Program members with respiratory devices in two categories: Respiratory Therapy Medication Delivery devices and Oscillatory Positive Expiratory Pressure/Positive Airway Pressure devices. The agreement, specific to Premier's committed AscenDrive performance group, recognizes the value of Monaghan's medical devices in treating COPD, asthma, and respiratory illness. The signed agreement acknowledges Monaghan's reputation for both industry-leading technology and proven clinical outcomes. Monaghan's devices consistently show evidence of better patient outcomes and are gold-standard medical devices. Monaghan's respiratory devices also align with Premier's desire to drive process efficiencies and value-driven healthcare spending.
UPXI

Hot Stocks

08:46 EDT Upexi consolidates third party logistics locations - Upexi will eliminate its California Third Party Logistics location, reduce its Nevada presence, and consolidate its Florida operations into a single location in Tampa. The Company is reducing these locations in order to optimize logistics in a central, highly-efficient, lower-cost, company-operated 3PL operation. Upexi estimates that it will achieve annual cost savings of approximately $1 to $1.5 million over the next six months as a result of this consolidation.
ITI

Hot Stocks

08:44 EDT Iteris awarded two-year contract for traffic signal timing by ODOT, no terms - Iteris announced that it has been awarded a two-year contract for statewide traffic signal timing and operation by the Ohio Department of Transportation ODOT , representing continued demand for Iteris' specialized consulting services to support another important mobility infrastructure project in a key geographic market. Under the contract, Iteris will develop signal timing plans for 53 key signalized intersections in Northeast Ohio, with additional locations throughout the state expected to come at a later date. ."
CRH

Hot Stocks

08:44 EDT CRH publishes restated segment information - As announced on 2 March, CRH has decided to transition to a new organisational structure, effective from 1 January 2023.
ENGA

Hot Stocks

08:43 EDT Bebuzee announces launch of revised website of Super App - Bebuzee announced the launch of its accompanying revised website of the Super App. Joseph Onyero, CEO, said: "We are very excited to start rolling out this product that we have put so much effort on. We are confident that this super app will gradually become an integral part of our daily lives in North America, Europe, Africa and South America. Not all the products on Bebuzee super app are on the website at present but most of the products are there."
NAOV

Hot Stocks

08:41 EDT NanoVibronix says shifted to more effective distributor in key market in 2023 - NanoVibronix issued a letter to shareholders from its Chief Executive Officer, Brian Murphy, providing a year in review and vision for 2023. "We managed to shift to a more effective distributor in our key market, reintroduced PainShield Plus and added senior, experienced personnel to navigate the increased burden of regulatory requirements, despite a challenging and transitional 2022...Dr. Dan Beeson in Washington DC wrote; "I was treating a patient 10 months post shingles in the rib cage, and she is doing much better with the PainShield Ultrasound. Your device was a game-changer for her making more improvement getting out of pain. She still has some medication for pain, and we are going to wean her down off of that, now she has confidence that she can get better." NanoVibronix's UroShield device showed a decrease in the number of blockages and infections and an increase in catheter satisfaction in the patients studied. In addition, evaluators concluded that the device has the potential to improve quality of life and reduce healthcare associated costs for patients with spinal cord injuries who experience recurrent blockages or infections and who have complicated catheter issues.," said the company.
DTSS

Hot Stocks

08:40 EDT Datasea expands business with 5G recharge payment platform - Datasea announced that on February 16, 2023, Hangzhou Shuhai Zhangxun Technology, a subsidiary of the Chinese operating company contractually controlled by the Company, has entered into a cooperation agreement with Hangzhou Chongda Technology to enhance 5G messaging recharge services in the Chinese market. Under the agreement, Chongda can purchase up to 1.1M virtual recharge cards of various denominations for 5G messaging within 12 months commencing from February 16, 2023, with a maximum total value of approximately USD 29.81M. Since the date of the agreement until the date of this announcement, Shuhai Zhangxun has provided end-users with 5G messaging recharge services worth approximately USD 0.85M, demonstrating the Company's unwavering commitment to the 5G messaging market in China. Datasea's CEO, Zhixin Liu, expressed her satisfaction with the collaboration's progress, emphasizing the importance of identifying potential customers that need their 5G messaging delivery services, and providing efficient and stable 5G messaging services to customers quickly.
TDOC

Hot Stocks

08:38 EDT Teladoc launches provider-based care for weight management, prediabetes program - Teladoc Health announced the expansion of Provider-Based Care for weight management and prediabetes programs. Currently available for diabetes and hypertension programs, the addition of Provider-Based Care services for weight management and diabetes prevention is crucial as 42% of adults in the United States today are estimated to live with obesity and 1 in 3 American adults have prediabetes. Provider-Based Care delivers a unique and integrated care experience for members, including access to a Teladoc Health physician for a personalized care plan, along with coaching for day-to-day guidance with actionable digital tools. By addressing the full range of cardiometabolic health risk factors associated with obesity, prediabetes, diabetes and hypertension, the company aims to drive better health outcomes for all members.
BAC

Hot Stocks

08:37 EDT Bank of America deposits continuing to perform well, says CEO
CLVR

Hot Stocks

08:37 EDT Clever Leaves expands presence in Brazil with partnership with Hypera Pharma - Clever Leaves announced that it has entered into a five-year agreement with Hypera Pharma to supply Clever Leaves' CBD-dominant oral solutions with the aim of treating various medical conditions and prescribing to Brazilian patients. "Hypera Pharma's history, innovative vision, capabilities, focus on high-quality, and commitment to sustainable growth is aligned with Clever Leaves' values, making them an ideal partner to promote and scale patient access to safe, pharmaceutical-grade cannabis products in Brazil. Expanding our presence in Brazil, a market that prioritizes patient treatment by enabling research and development to ensure technical and quality standards, will open doors for potential new developments and is further evidence of how our platform can support the global pharmaceutical industry by allowing it to engage in the world of cannabis-based therapies with patient safety and product quality at the forefront," said Andres Fajardo, CEO of Clever Leaves.
BAC

Hot Stocks

08:37 EDT BofA CEO: U.S. consumer finances remain generally healthy
JAN

Hot Stocks

08:36 EDT JanOne completes pre-IND meeting with FDA for Jan123 formula - JanOne has completed a pre-IND meeting with the FDA regarding Jan123. Jan123 is the company's unique oral delivery of low dose naltrexone formulated to treat complex regional pain syndrome, an orphan disease of severe, debilitating impact. The Pre-IND meeting with the FDA produced a path toward formal drug application. The agency's feedback will be used to move Jan123 toward a New Drug Application under a 505-b2 designation.
BAC

Hot Stocks

08:36 EDT Bank of America continues to expect shallow recession, says CEO - Comments taken from Q1 earnings conference call.
SLP

Hot Stocks

08:36 EDT Simulations Plus receives U.S. FDA renewal for DILIsym software licenses - Simulations Plus announced that the U.S. FDA has renewed its licenses to the DILIsym software platform, the flagship quantitative systems toxicology QST software for predicting and investigating drug-induced liver injury DILI . The one-year renewal provides continued access to DILIsym software for authorized FDA employees across all FDA divisions. Dr. Paul B. Watkins, chair of the Scientific Advisory Board of the DILI-sim Initiative, commented, "The FDA's renewal of these licenses endorses the value of DILIsym software in both predicting liver safety liabilities and defining the underlying mechanisms, which are critical to evaluating risk. The recent signing of the FDA Modernization Act 2.0 by President Biden, which encourages the FDA to limit animal use in drug development, should be a positive catalyst for greater utilization of DILIsym software in drug development. In my role as Chair of the SAB, I am very excited about the direction of the public-private partnership that is guiding further development of the DILIsym platform that will benefit many key stakeholders."
GS

Hot Stocks

08:36 EDT Goldman Sachs slips 3% to $328.60 after Q1 results - Shares of Goldman Sachs are down 3.3% or $11.08 at $328.60 in pre-market trading after the company's Q1 results.
DYAI

Hot Stocks

08:36 EDT Dyadic receives U.S. patent for making seasonal, pandemic influenza vaccine - Dyadic International announced that the company has received a Notice of Allowance from the U.S. Patent and Trademark Office, USPTO, for patent application 16/640,483, titled "PRODUCTION OF FLU VACCINE IN MYCELIOPHTHORA THERMOPHILA", and is expected to provide patent protection through 2038. The Patent will cover claims for the development and manufacture of seasonal and pandemic influenza vaccines from the Company's C1 protein production platform. The human influenza vaccine market is currently valued at approximately $8 Billion USD and expected to grow to over $12 by 2028 with multi-valent vaccines leading the market. "The COVID pandemic has provided important insights in the fight against infectious diseases. There is an urgent need for more efficient manufacturing platforms that can rapidly and affordably produce more complex vaccines, in greater quantities, to address a global rather than regional population. The need is for humans, and with the recent outbreak of Avian Flu, for animal health as well," said Mark Emalfarb, Chief Executive Officer of Dyadic.
FLR

Hot Stocks

08:35 EDT Fluor signs MOU with Longview to serve as engineering, construction partner - Fluor announced that it has signed a memorandum of understanding, or MOU, with Longview Fusion Energy Systems to serve as its engineering and construction partner in designing and planning laser fusion energy for the global energy market. At full capacity, Longview's laser fusion power plants are slated to provide carbon-free, safe, economical and sustainable energy that can power the needs of a small city or provide process heat or power to drive industrial production of the materials needed for operational necessities like steel, fertilizer and hydrogen fuel.
KNTNF

Hot Stocks

08:35 EDT K92 Mining appoints Anne Giardini as chair of the board - K92 Mining announced the appointment of Anne Giardini as the Company's Chair of the Board of Directors. Giardini, KC, who has served as an independent director of K92 since 2020, brings 35 years of experience as a director, senior executive, lawyer, journalist and author.
IMAX

Hot Stocks

08:34 EDT Imax and Megarama add three locations in France and Morocco - Imax and French exhibition company Megarama announced an agreement for three new Imax systems in France and Morocco. The new deal will more than triple Imax's footprint with Megarama and bring the number of Imax systems in France to 29, including 23 currently open and another 6 set for installation. Two of the new Imax with Laser locations will be in France - in Givors and Boulogne-Sur-Mer - and one in Rabat, the capital city of Morocco. With this new deal, Megarama becomes Imax's second biggest commercial client in France.
SLS

Hot Stocks

08:34 EDT Sellas Life Sciences IDMC recommends REGAL trial continue as planned - SELLAS Life Sciences announced a positive review of the ongoing Phase 3 REGAL clinical trial of galinpepimut-S in acute myeloid leukemia. The Independent Data Monitoring Committee, IDMC, performed a routine, prespecified risk-benefit assessment of unblinded data from the study and has recommended that the trial continue without modifications. The IDMC has further recommended to meet again within Q3 2023 and endorsed all clinical trial initiatives SELLAS has undertaken to advance GPS in the REGAL study, including the addition of clinical sites in China. "This positive IDMC review marks another significant milestone in GPS development and builds on the favorable profile of our study drug, galinpepimut-S," said Angelos Stergiou, MD, ScD h.c., President and Chief Executive Officer of SELLAS. "Enrollment continues in our global Phase 3 REGAL registrational study, which currently remains on track for interim analysis by the end of 2023 or early 2024."
LSTA

Hot Stocks

08:33 EDT Lisata, WARPNINE announce first patient treated in iLSTA trial of LSTA1 - Lisata Therapeutics and WARPNINE Incorporated announced the treatment of the first patient in the iLSTA Trial of Lisata's LSTA1 in combination with standard-of-care chemotherapy and immunotherapy as a first-line treatment in locally advanced non-resectable pancreatic ductal adenocarcinoma. "Dosing the first patient in our iLSTA Trial of LSTA1 in patients with pancreatic cancer in Australia is an important step in our mission to create new hope for patients by providing meaningful treatments to those with few remaining alternatives. We believe that LSTA1 represents a new treatment option for these patients who haven't been fully served by standard-of-care alone," stated Kristen Buck, M.D., Executive Vice President of R&D and Chief Medical Officer of Lisata. "We are thrilled by the progress being made to help advance LSTA1 through the clinical trial process and are grateful to WARPNINE for their financial and operational support."
UAL

Hot Stocks

08:33 EDT United Airlines expands in South Pacific including direct flight to Christchurch - United Airlines announces the largest South Pacific network expansion ever to and from the continental U.S., including the first non-stop flight between San Francisco and Christchurch set to commence on December 1. United will be the only carrier to directly connect the U.S. and the South Island of New Zealand. The carrier is adding new direct flights from Los Angeles to Brisbane and Auckland and increasing service to the region from its San Francisco hub with daily flights to Brisbane, twice daily flights to Sydney and flying larger aircraft to Melbourne.
PHUN

Hot Stocks

08:32 EDT Phunware receives notice of allowance for patent on geofence event predictions - Phunware announced that the United States Patent and Trademark Office has issued a Notice of Allowance for the Company's US patent application 17/362,765 titled Method and Apparatus for Geofence Event Predictions. This capability will significantly enhance the capabilities of Phunware's location-based services and enable brands to deliver personalized, context-aware experiences to their users. The patent covers a method for predicting geofence events by retrieving non-contemporaneous geofence predictor data of a mobile device, including past and future geographic data. By analyzing this data, along with geofence data of the mobile device, the system develops a future geofence event prediction, including a latitude, longitude, time and confidence level for the prediction. This innovative technology allows businesses to better understand their users' behavior patterns and preferences, ultimately improving the overall user experience. By detecting patterns in past geofence events and incorporating future engagement opportunities, Phunware's geofence event prediction technology enables businesses to deliver highly targeted, timely and relevant content to users based on their anticipated location and activities.
SABS

Hot Stocks

08:32 EDT SAB Biotherapeutics announces U.S. FDA grants BTD to SAB-176 - SAB Biotherapeutics announced that the U.S. Food and Drug Administration, FDA, has granted Breakthrough Therapy Designation, BTD, to SAB-176, an investigational therapeutic, for post-exposure prophylaxis for Type A and Type B influenza illness in high-risk patients, including those who have anti-viral resistant strains. On April 13, SAB announced that the FDA had granted Fast Track designation to SAB-176, and that the company had also received FDA guidance and regulatory alignment on advancing SAB-176 into the next phase of development through initiation of a Phase 2b dose-range finding efficacy and safety trial in patient populations at high-risk for developing severe disease. "Influenza continues to pose considerable health concerns both in the U.S. and on a global scale. This Breakthrough Therapy designation signifies an important step forward in our fight against this disease," said Eddie Sullivan, PhD, co-founder, President & CEO of SAB Biotherapeutics. "We are proud that based on generated preclinical and clinical evidence, SAB-176 has received both Breakthrough and Fast Track designations, a combination rarely seen. These designations further assure us that SAB-176 has a clear regulatory and clinical development path to progress this important therapeutic."
GH

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08:31 EDT Guardant Health gets Medicare coverage for Guardant360 Response test - Guardant Health announced that Palmetto GBA, a Medicare administrative contractor for the Molecular Diagnostics Services program has conveyed coverage for the Guardant360 Response test. Guardant360 Response is the first blood-only test that enables doctors to track molecular response through changes in circulating tumor DNA levels, to get an early indication of metastatic or advanced cancer patient response to immune checkpoint inhibitor therapy. Following this decision, the Guardant360 Response test is now covered for fee-for-service Medicare patients in the U.S. with metastatic or inoperable solid tumors who are on an immune checkpoint inhibitor therapy. The coverage includes a Guardant360 CDx or LDT test before initiating therapy to establish a ctDNA baseline and a Guardant360 Response test 4 to 10 weeks after the therapy has been initiated to measure the change in ctDNA level. "We are pleased that Medicare has taken this important step to make treatment response monitoring more widely available in order to assist oncologists in making more informed therapeutic decisions for their patients with solid tumor cancers," said Helmy Eltoukhy, Guardant Health co-CEO.
FLR

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08:29 EDT Fluor signs MOU with Longview Fusion Energy Systems for laser fusion power - Fluor announced that it has signed a memorandum of understanding MOU with Longview Fusion Energy Systems to serve as its engineering and construction partner in designing and planning laser fusion energy for the global energy market. "Fluor is a leader in designing and building solutions to create a sustainable future and our partnership with Longview Fusion Energy Systems builds upon that experience," said Tom D'Agostino, group president of Fluor's Mission Solutions business. "From developing and constructing large-scale energy facilities to designing, building and operating complex chemical processing and innovative industrial projects, our expertise helps clients reduce greenhouse gas emissions, improve energy efficiency and deliver cleaner, decarbonized projects. We look forward to working with Longview on the mission to demonstrate the feasibility of laser fusion technology and deliver it to the commercial market." Under the MOU, Fluor will leverage its global experience in developing and constructing complex, large-scale facilities to provide preliminary design and engineering to support the development of Longview's fusion-powered plant.
RMED

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08:27 EDT Ra Medical Systems CEO Will McGuire resigns, David Jenkins named interim CEO - Ra Medical Systems announced the resignation of its CEO, Will McGuire, for personal reasons. The resignation will be effective April 28, 2023. In conjunction with his resignation as CEO, Mr. McGuire is also resigning from the RMED board of directors.The RMED board of directors, as part of its governance commitment, last month established a committee for examining a transition at the CEO level. Mr. David Jenkins, the Company's Executive Chairman of the Board, will serve as Interim CEO until a full-time replacement is named.
DZSI

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08:26 EDT St. Kitts-Nevis Cable to use DZS to replace existing cable network - DZS announced that St. Kitts-Nevis Cable Communications, a leading local provider of internet and television services, is leveraging DZS Velocity Optical Line Terminals and DZS Helix Optical Networking Terminals to replace its existing legacy Hybrid Fiber-Coaxial cable network with a world-class, all-fiber Gigabit Passive Optical network capable of delivering gigabit broadband speeds. This network and services transformation is being enabled by longtime DZS partner Lucas Telecom, and will result in significantly increased broadband speeds, service turn-up agility and improved reliability for The Cable's residential and business customers which include financial services, hospitality, small-to-medium sized enterprise, and educational and governmental institutions.
CUEN

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08:26 EDT Cuentas announces compliance with all Nasdaq continued listing rules - Cuentas announced that the Company has received formal notification from the NASDAQ Hearings Panel that the Company has evidenced full compliance with the minimum bid price requirement and all other applicable criteria for continued listing on The NASDAQ Stock Market, that all compliance matters have been resolved, and that the Panel has closed the Company's compliance file. To evidence compliance with the minimum bid requirement, the Company needed to evidence a closing bid price of at least $1.00 per share for a minimum of ten, but generally not more than 20, consecutive business days. The Panel has determined to continue the listing of the Company's securities on The NASDAQ Stock Market and the Company has no further deficiencies.
WMT...

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08:26 EDT Walmart teams with Cummins and Chevron to debut 15L renewable natural gas engine - Walmart (WMT) is reaching a new destination in its goal for a zero-emissions transportation fleet with the debut of the first North American-and the first of five- 15-liter compressed natural gas engine that will be incorporated into Walmart's private fleet. The X15N engine is supplied by Cummins (CMI) and fueled by Chevron (CVX) with compressed natural gas CNG linked to renewable natural gas. The Walmart truck will make its inaugural trip from Indiana to California, making pit stops along the way to refuel at Chevron stations. Last year, Walmart announced several first-of-their-kind initiatives among its Class 8 transportation fleet as the retailer pursues its goal to achieve zero emissions across global operations by 2040. And just in time for Earth Week, the introduction of this CNG-powered truck is an important milestone in the retailer's journey. "Walmart transportation is focused on the continuous piloting of solutions that aren't just changing the industry, but are having a lasting impact on the world," said Fernando Cortes, senior vice president of transportation at Walmart. "We are proud to team with Cummins and Chevron to develop industry-leading advancements that pave toward a lower carbon future."
SOBR

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08:25 EDT SOBRsafe enters distribution agreement with Fox Group - SOBR Safe signed a distribution agreement with previously announced customer the Fox Group. Through its commercial driver training portfolio, the Fox Group has established relationships with significant employers in key SOBRsafe markets such as oil and gas, mining and trucking. The Fox Group joins Alco Prevention Canada as SOBRsafe's initial Canadian representatives, rounding out a group of four new distributors the Company has signed in 2023. SOBRsafe now has 13 North American distributors.
MDGS

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08:24 EDT Medigus says Charging Robotics completes transaction with Fuel Doctor - Medigus announced that its subsidiary, Charging Robotics has completed a share exchange transaction with Fuel Doctor, a Delaware corporation, listed on the OTC Market. Medigus currently holds 60% of the common stock of FDOC. As part of the exchange agreement, FDOC acquired all of the issued and outstanding shares of Charging Robotics on a fully diluted basis. As a result Charging Robotics became a wholly owned subsidiary of FDOC. At the closing Medigus received, in exchange for all of its shares in Charging Robotics, such number of newly issues shares of FDOC common stock equal to 60% of the total number of shares of FDOC common stock issued and outstanding as of the closing on a fully diluted basis. Subject to several pre-determined milestones, Medigus has the option to increase its holdings in FDOC up to 71%. At closing, FDOC had $1 million in cash. Charging Robotics is currently in the process of changing FDOC's name and stock symbol.
MTNB

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08:24 EDT Matinas BioPharma announces presentation on MAT2203 at EECMID - Matinas BioPharma announces that Marisa Miceli, MD, Professor of Medicine, Specializing in Fungal Infections and Transplant Diseases, Division of Infectious Diseases Internal Medicine at the University of Michigan and her team delivered an oral presentation earlier today at the 33rd European Congress of Clinical Microbiology & Infectious Diseases, EECMID, in Copenhagen discussing MAT2203's clinical impact in treating a compassionate use patient suffering from Rhodotorula mucilaginosa, a rare and opportunistic invasive fungal infection. Key elements of Dr. Miceli's team presentation included: Rhodotorula are a genus of pigmented yeasts and represent a rare, but opportunistic and emerging threat often highly resistant to antifungal therapy. The patient was at risk of amputation of her foot where the infection was located and was generally unable to walk. The patient began treatment with liposomal IV-administered amphotericin B but developed serious kidney toxicities attributed to the use of IV-amphotericin B. As a result, treatment with IV-amphotericin B was discontinued and Dr. Miceli applied to Matinas' Compassionate Use Expanded Access Program for treatment with MAT2203. The patient was admitted for monitored initiation of MAT2203 with a dosing regimen of 300mg, four times a day. Following initiation with MAT2203, the patient's renal function improved and remained at baseline throughout treatment. While taking MAT2203, the patient experienced none of the electrolyte abnormalities evident while taking IV-amphotericin B. The patient received MAT2203 daily for six months and ended therapy in January 2023 following complete clinical resolution of the fungal infection while regaining the use of her foot
BOWL

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08:24 EDT Bowlero to acquire Andy B's in Tennessee, terms undisclosed - Bowlero announced that it has entered into a definitive agreement to acquire Andy B's in Tennessee. The completion of this acquisition will mark the company's first center in the state. Andy B's is located in Bartlett, Tennessee, 13 miles outside of Memphis. This 44-lane center is made up of 32 traditional lanes and 12 private lanes featuring state-of-the-art audio and lighting with 50 feet of video displays. Andy B's is also home to an interactive arcade, a snack bar and grill, and a full-service bar. Andy B's will open as a Bowlero upon completion of the acquisition.
WWE

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08:21 EDT WWE & Fanatics expand partnership to include global event retail merchandise - WWE and Fanatics announced an expansion of their existing comprehensive, long-term sports and entertainment partnership, which will now see Fanatics assume operations of WWE's global event merchandise business. The deal will kick off on May 1 before WWE's premium live event, Backlash . Under the expanded partnership, Fanatics Commerce, the company's e-commerce, licensed merchandise and physical retail operations division, will manage the on-site event retail experience for WWE's annual calendar of 300-plus events, including premium live events such as WrestleMania, Royal Rumble and SummerSlam. Fanatics will work closely and collaboratively with world-class teams at WWE who previously operated the event retail business in-house for decades to optimize the event shopping experience for its growing global fanbase. This includes curating an enhanced in-venue product offering with more localized merchandise collections, creating innovative event retail stores and experiences, as well as utilizing Fanatics-operated team stores during various live events. Fanatics holds physical retail partnerships with more than 50 professional and college teams across several sports. The expansion follows strong commercial results for WWE across its retail channels in 2022, including record-breaking demand for WWE merchandise.
HTGM

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08:21 EDT HTG Molecular announces first quarter milestone achievements for drug discovery - HTG Molecular Diagnostics announced the achievement of three significant drug discovery business milestones in the first quarter of 2023. As reported in January 2023, HTG filed a patent application on December 28, 2022, which included claims directed toward specific compounds, pharmaceutical compositions and methods of treating or preventing disease by administration of the compounds for its first target and indication. That work has now been followed up with the first of the key first quarter 2023 milestones - in vitro demonstration of efficacy of the lead compounds both as a standalone therapy and in combination with the current standard of care. HTG considers this result a powerful demonstration of its medicinal chemistry platform. The second key milestone achieved during the first quarter was the use of the company's proprietary HTG EdgeSeq RNA profiling platform to biologically interrogate the lead molecules. This data, along with other primary and secondary data, was then introduced into the company's AI-driven drug discovery engine, resulting in the creation of a second generation of molecules. The second generation of molecules have been subjected to the same in vitro experiments as the first, demonstrating improved efficacy over the first generation of molecules. The third milestone achieved was the use of our AI-driven drug discovery engine to design compounds using transcriptomic data as the starting point. These system-designed compounds showed highly similar characteristics to our lead compounds that were designed starting with the target.
NVCT

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08:21 EDT Nuvectis Pharma recaps poster presentation highlights on NXP800 - Nuvectis Pharma provided highlights from the poster presentation of NXP800 that took place yesterday at the American Association for Cancer Research Annual Meeting 2023 in Orlando, FL. Ron Bentsur, Chairman and Chief Executive Officer of Nuvectis, commented, "Cancer of the bile duct, or cholangiocarcinoma, is a serious unmet medical need for which new treatment options are greatly needed. With approximately 10,000 new cases per year in the United States, the clinical management of CCA is complex, with only about 30% of patients eligible for surgical resection and the rest with unresectable disease, which carries a dismal prognosis with a median survival of less than 1 year. Unfortunately, approximately 60% of the patients that do undergo surgical resection experience disease recurrence and face similar outcomes." Mr. Bentsur concluded, "We are excited about the data generated as we continue to evaluate clinical development opportunities for NXP800."
MASI

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08:21 EDT Masimo announces FDA clearance for Rad-G with Temperature - Masimo announced that the Rad-G with Temperature has received FDA 510(k) clearance. Rad-G with Temperature is a rugged, versatile, handheld monitor that provides clinically proven SET pulse oximetry, respiration rate from the pleth, and other important parameters alongside non-contact infrared clinical thermometry. With its long-lasting rechargeable battery, robust rubber casing, light weight, and the added convenience of integrated noninvasive forehead thermometry, Rad-G with Temperature makes it easier for care teams to quickly measure vital signs using a single, compact, portable device and make informed decisions anywhere patient assessment is needed. Rad-G with Temperature is designed for use in a variety of settings, including physicians' offices, outpatient services, urgent care facilities, wellness clinics, and in first-responder scenarios, both indoors and in the field.
AUUD

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08:19 EDT Auddia announces interm bridge financing, withdraws S-1 registration statement - Auddia has secured bridge financing from insiders and other investors on more favorable terms than are currently available in the public capital markets. The Company believes this interim financing will bridge to potential critical milestone achievements that include improved faidr usage metrics and executing business development agreements with one or more streaming AM/FM radio station aggregators that could significantly accelerate Auddia's growth trajectory. The bridge financing includes an increase in its existing $2 million non-convertible, term debt, from an existing affiliate investor to $2.75 million, as well draw downs on its previously disclosed $10M equity line, which includes more favorable terms than other currently available public financing alternatives. In light of the successful interim financing, the Company will withdraw its pending S-1 registration statement for a proposed secondary stock offering. The Company has explored numerous potential acquisition targets over the past year and a half and continues to explore new opportunities. At present, the Company is in advanced active discussions with three properties and is targeting to execute one or more agreements in the near term. Based on diligence to date the Company believes the three target properties under active discussion aggregate to approximately $6.5M in current annual revenue with greater than 50% free cash flow. Current revenue is primarily from digital ad revenue and software sales. The Company believes existing digital ad revenue from these properties can be increased through active management to provide immediate synergies. The total user base listening to AM/FM streams across all three properties is over 10 million monthly active users worldwide, with 1.1 million being U.S. users that represent a free tier that can be offered a commercial free premium experience through faidr, resulting in new subscription revenue to Auddia.
FEMY

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08:18 EDT Femasys's FemaSeed granted product approval in Canada - Femasys announced the Health Canada, the Public Health Agency of Canada, has granted product approval of FemaSeed, the first-ever infertility solution designed to deliver sperm directly to where contraception occurs. FemaSeed is Femasys' localized artificial insemination option that is designed to be less invasive and more affordable than assisted reproduction, such as in vitro fertilization or intracytoplasmic sperm injection. "We are thrilled to gain approval of FemaSeed in Canada, now being able to offer a safe, novel and affordable option for treating infertility," stated Kathy Lee-Sepsick, Femasys' founder, president, chief executive officer. "Our advanced approach delivers sperm directly to the area where conception occurs in the fallopian tube. Prior to FemaSeed, Femasys' first-of-its-kind in-office ultrasound diagnostic product FemVue, which is also approved in Canada, can be used to assess that the fallopian tube is patent. Both of these proprietary solutions will offer women and couples in Canada cutting-edge options that are affordable and safe."
DARE

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08:17 EDT Dare Bioscience announces publication of data from Phase 1 clinical trial - Dare Bioscience announced that Climacteric, the official journal of the International Menopause Society, published safety and acceptability results from a Phase 1 clinical trial of DARE-HRT1, an investigational ethylene vinyl acetate copolymer intravaginal ring designed to release bio-identical 17beta-estradiol and progesterone over 28 days. DARE-HRT1 is being developed for the treatment of moderate-to-severe vasomotor symptoms, VMS, due to menopause in women with intact uteri. Hormone therapy is used to treat VMS and genitourinary syndrome associated with menopause. DARE-HRT1 has the potential to be the first FDA-approved product to offer vaginal delivery of combination bio-identical estradiol and bio-identical progesterone hormone therapy in a convenient monthly format. The North American Menopause Society's guidance on hormone therapy states that dosing estrogen and progestogen in combination may offer important benefits to women, and NAMS observed that non-oral routes of administration may offer advantages over orally administered therapies. Approximately 30 healthy, postmenopausal women participated in the open-label, three-arm Phase 1 study. The primary objective of the study was to assess the pharmacokinetics from the two dosage strengths of the DARE-HRT1 IVRs. The secondary objective of the study was to assess the safety of the IVRs while the exploratory objectives were to assess usability and participant tolerability of the IVRs. The study demonstrated that the DARE-HRT1 IVRs, in general, were safe and well tolerated in healthy postmenopausal women and treatment emergent adverse events profiles were comparable between the DARE-HRT1 groups and the reference oral regimen group.
AAPL

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08:17 EDT Apple CFO sells $11.6M in common stock - In a regulatory filing, Apple disclosed that its CFO Luca Maestri sold 70K shares of common stock on April 13th in a total transaction size of $11.6M.
ARQT

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08:17 EDT Arcutis Biotherapeutics announces FDA acceptance of roflumilast foam NDA - Arcutis Biotherapeutics announced the U.S. Food and Drug Administration has accepted for review the company's new drug application for roflumilast foam 0.3% for the treatment of seborrheic dermatitis in individuals 9 years of age and older. The application was assigned a Prescription Drug User Fee Act target action date of December 16, 2023.
AIV

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08:16 EDT Aimco holder Land & Buildings issues letter urging evaluation of alternatives - Land & Buildings Investment Management, a large shareholder of Apartment Investment and Management Company or Aimco" or the issued an open letter to the Company's Board of Directors. The letter said in part: "As you know, Land & Buildings remains a large shareholder of Aimco and has continued to engage with the Company since the 2022 Annual Meeting of Shareholders at which our independent nominee, James P. Sullivan, was elected to the Board. Since that time, we have grown increasingly concerned about the Company's continued failure to act with urgency in exploring ways to maximize value for shareholders, especially in light of Aimco continuing to trade at a deep discount to its own stated net asset value . While we note the recent appointment of Sherry L. Rexroad to the Board following the resignation of Terry Considine, we believe more action is needed. At this point, the path forward is clear to us. Aimco must run a full public strategic review process to evaluate all potential alternatives - including a sale - to deliver value for shareholders. It is our understanding that Morgan Stanley has been retained by the Company and we encourage the Board to make full use of this resource...Based on our analysis, we believe a potential sale could result in between 40% and 60% upside to the current trading price. We encourage and expect the Board to act with urgency. The economic environment is still on sound footing and the capital markets remain open for a potential transaction, but either of those variables could change rapidly. We will continue to advocate for the best interests of all shareholders and look forward to a clear update on the status and specifics of the ongoing review of a "broad range of options" to enhance value.
SHLS

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08:16 EDT Shoals Technologies to supply BLA+ for 120 MW solar project - Shoals Technologies Group announced it has been awarded a 120 MW contract to supply its BLA+ solution to a utility-scale solar project in Western Australia. The BLA+ solution, formerly known as BLA 2.0, is a bundled offering that combines the BLA system with all the components required to attach the BLA to the racking system, including wire management, support wire and tensioning systems to create a single integrated offering. Deliveries for the project are expected to be completed by Q4 2023.
MULN

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08:15 EDT Mullen Automotive enters partnership with Global EV, EV Technologies - Mullen Automotive announces a partnership with Global EV Technology, Inc. and EV Technologies, with initial development for improving energy management technology in electric vehicles for greater range and vehicle performance. Under the newly formed entity, Mullen owns 51% and will consolidate the results of its operations in Mullen Automotive, Inc. Under the agreement between the parties, Global EV Technology will be contributing its technology and existing contracts to MAEO, and Mullen will provide capital, execution and commercialization to grow the business. Both companies will be contributing and working together on known verified technology for improving existing vehicle performance and extending battery range. As this technology has immediate and key implications for electric vehicles, MAEO's initial development is focused on improving Mullen's lineup of commercial and consumer EVs.
BEEM

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08:14 EDT Beam Global receives order fo EV ARC solar-powered EV charging systems - Beam Global announced a global automotive brand has placed an order for EV ARC(TM) solar-powered EV charging systems.
GALT

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08:14 EDT Galectin Therapeutics attended 2023 conference sponsored by AASLD - Galectin Therapeutics attended the 2023 Emerging Topic Conference on NASH Cirrhosis: From Mechanisms to Management, sponsored by the American Association for the Study of Liver Diseases, AASLD. The Conference took place in Los Angeles, March 25-26, 2023. The AASLD has created a new forum to share knowledge around NASH cirrhosis and explore current and future opportunities for patients affected with this devastating disease. The conference was attended, moderated, and chaired by clinical investigators who have enrolled their patients in Galectin Therapeutics' ongoing NAVIGATE study, an innovative phase 2b/3 study evaluating the effect of belapectin for the primary prevention of esophageal varices in patients with portal hypertension due to NASH cirrhosis. The conference reiterated the known limitation of liver biopsy, including the lack of sensitivity for response criteria in cirrhotic patients and the difficulty predicting the timing of cirrhotic decompensation events. Dr. Pol Boudes, Galectin Therapeutics Chief Medical Officer, stated: "For far too long, liver cirrhosis has been a neglected disease for drug developers, and we welcome the organization of this conference by the AASLD. We are already facing a major crisis of patients afflicted with NASH cirrhosis, and future numbers are only projected to increase. If these projections are accurate, the health system will be completely overwhelmed. In the U.S., the shortage of transplants will be dramatic, and the cost of liver transplantations to society will lead to further rationing. The situation is already dramatic and will grow even worse in countries that have limited or no possibility of liver transplants."
GRWG

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08:12 EDT GrowGeneration acquires store in Jackson, Michigan, no terms - GrowGeneration announced the acquisition of inventory and equipment from Mighty Grow, a family owned and operated business located in Jackson, Michigan serving the gardening community for over 10 years. As a part of the transaction, GrowGen also took over the existing store location at 2418 W. Michigan Ave. Jackson, MI. Darren Lampert, Co-Founder and Chief Executive Officer of GrowGen, said, "We are excited to expand our retail footprint in Michigan with this strategic transaction which represents our eighth location in the state. Mighty Grow has successfully served the broader Jackson growing market for over 10 years through focusing on customer service and offering high quality supplies to its customers. We look forward to continuing this location's strong legacy and providing the same caliber of service and product offerings to the local and surrounding growing markets." Lampert continued, "GrowGen remains committed to providing high-quality products and having the largest product selection, best service, and most knowledgeable grow professionals in the industry. This transaction supports those commitments and enhances our overall portfolio of stores to best serve both our commercial and home-grow customers."
OPTN

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08:12 EDT Optinose announces inducement grants under Nasdaq listing rule - OptiNose announced that the company has granted non-qualified stock option awards to purchase an aggregate of 54,000 shares of its common stock to three new employees as an inducement material for accepting employment with OptiNose. The stock option awards were granted outside of the OptiNose, Inc. 2010 Stock Incentive Plan in accordance with Nasdaq Listing Rule 5635(c)(4) The stock options were granted to the new employees on their hire date April 17, 2023 with an exercise price of $2.05 which is equal to the closing price of the company's common stock as reported by Nasdaq on the grant date. The stock options have a 10-year term and vest over four years, with one-fourth of the shares underlying the stock option vesting on the first anniversary of the grant date and the remainder vesting in thirty-six equal monthly installments thereafter. Vesting of the stock options is subject to continued service with the company through the applicable vesting date.
FOXO

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08:12 EDT FOXO Technologies COO Taylor Fay resigns - FOXO Technologies announced the resignation of Taylor Fay as COO of the company, effective April 28.
MYGN

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08:12 EDT Myriad, Intermountain Precision now offer solid tumor testing in all states - Myriad Genetics and Intermountain Precision Genomics are now certified to offer solid tumor testing to patients in all 50 U.S. states after receiving the New York State Clinical Laboratory Permit. This achievement follows a recent site inspection as part of the New York State Department of Health Clinical Laboratory Evaluation Program. "The NYS certification represents an important step forward in the advancement of precision medicine by increasing access to genetic testing that can help patients with cancer and their providers determine more targeted treatment decisions," said Michael Lyons, president of Oncology, Myriad Genetics. "Working in close collaboration with Intermountain Precision Genomics, we're now able to offer the complete Precise(TM) Oncology Solutions suite in all 50 states." Myriad's Precise Tumor test, also offered by Intermountain Precision Genomics as TheraMap: Solid Tumor, analyzes a patient's tumor DNA to discover what changes, or gene mutations, are causing the cancer. Specialists apply the results to recommend a targeted treatment plan for the patient's unique tumor profile.
NISN

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08:11 EDT Nisun International enters into wheat flour sales and purchase agreement - Nisun International's controlled affiliate, Fintech Supply Chain Management Shandong, has entered into a wheat flour sales and purchase agreement with Binzhou Zhongyu Food, a manufacturer in China with a green and environmental circular economy industrial chain from wheat seeds to deep production. The company expects to accelerate its business growth in the market of wheat flour through the execution of the agreement. China is the largest wheat consumer and producer in the world. Pursuant to the Agreement, Zhongyu Food would notify Shandong Fintech of the purchase quantity, delivery date, and other requirements one day in advance and pay the full amount for the goods within 10 business days from the delivery date. It is estimated that by the end of 2023, the scale of cooperation will exceed RMB 600M, approximately $87.3M.
MMM AMZN

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08:11 EDT 3M Health Information Systems collaborates with AWS on AI - 3M Health Information Systems announces a collaboration with Amazon Web Services (AMZN) to accelerate the innovation and advancement of 3M M Modal ambient intelligence. As part of the collaboration, 3M (MMM) will use AWS Machine Learning and generative AI services, including Amazon Bedrock, Amazon Comprehend Medical and Amazon Transcribe Medical, to help expedite, refine and scale the delivery of 3M's ambient clinical documentation and virtual assistant solutions. Joining forces with AWS will help 3M to further transform the patient-physician experience, placing the focus back on the patient and reducing administrative burden for physicians.
ADVM

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08:11 EDT Adverum Biotechnologies granted ILAP designation for Ixo-vec in Wet AMD - Adverum Biotechnologies announced that the United Kingdom's Medicines and Healthcare Products Regulatory Agency as granted Ixo-vec, an investigational gene therapy for the treatment of wet AMD, an Innovation Passport under the Innovative Licensing and Access Pathway. The Innovation Passport is the first step in the ILAP process, triggering the MHRA and its partner agencies, including the National Institute for Health and Care Excellence and the National Health Service England, to partner with Adverum to charter a roadmap for regulatory and development milestones with the goal of early patient access in the United Kingdom.
ARDX

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08:11 EDT Ardelyx resubmits New Drug Application to U.S. FDA for XPHOZAH - Ardelyx announced the resubmission of a New Drug Application, NDA, to the U.S. Food and Drug Administration, FDA, for the approval of XPHOZAH for the control of serum phosphate in adult patients with chronic kidney disease on dialysis who have had an inadequate response or intolerance to a phosphate binder therapy. An Acknowledgement of Receipt letter from the FDA, confirming the resubmission is complete, is expected in mid-May. We expect that the letter will include the classification of the resubmission and the review goal date. The NDA is supported by a comprehensive development program that included more than 1,200 patients in three Phase 3 clinical trials evaluating the safety and efficacy of XPHOZAH, all of which met their primary and key secondary endpoints, as well as two additional Phase 4 open-label clinical trials.
HUMA

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08:10 EDT Humacyte announces publication of preclinical study on HAV to expanded ePTFE - Humacyte announced the publication of a preclinical study in the Journal of Trauma and Acute Care Surgery comparing the use of its Human Acellular Vessel, HAV, to expanded polytetrafluorethylene, ePTFE, grafts for vascular repair following arterial trauma. In the preclinical study the HAV performed better than ePTFE on multiple indices. In this comparative preclinical study, 36 pigs were randomly assigned to treatment groups receiving either the HAV or an ePTFE graft to reconstruct a severed iliac artery after vascular trauma. The animals were monitored for 28 days and routinely assessed for recovery of hind limb function, graft patency, and circulating biochemical markers of tissue ischemia and reperfusion injury. At the conclusion of the study, the HAV and ePTFE implants were removed and histologically evaluated for host cellular response. The data observed in this preclinical study indicate that the HAV performed better than ePTFE on multiple indices, including recovery of limb function after six hours of ischemia and conduit patency. In addition, the HAV showed no incidence of infection, degradation, aneurysm or mechanical failure. Host recellularization of the HAV conduits was observed to be greater than that of ePTFE grafts. "We believe the results of this study underscore the potential of the HAV to save the lives and limbs of those suffering from vascular injury and peripheral tissue ischemia," said Rob Kirkton, Ph.D., Director of New Product Development at Humacyte and lead author of the publication.
MIND

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08:09 EDT MIND Technology receives orders for wind farm project - MIND Technology's Seamap unit has received orders from The Fraunhofer Institute for Wind Energy System IWES for hydrophone arrays and related equipment related to the Manta Ray G2 system. The orders total approximately $0.8M and are expected to be delivered in FY24.
HASI

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08:08 EDT HASI makes equity investment in solar-plus-storage portfolio in California - HASI and ForeFront Power, a developer and asset manager of commercial and industrial-scale solar energy and battery storage projects, have entered into a follow-on equity investment for a portfolio of distributed solar and solar-plus-storage projects located across California. The transaction, which reached financial close on March 30, builds upon an initial co-sponsor equity investment for a separate U.S. distributed solar portfolio that HASI made with ForeFront Power in 2022. The portfolio comprises 48.5 MW-DC of commercial and industrial ground-mounted, carport, and rooftop solar, including several projects paired with battery storage totaling 3.7 MW. Approximately 36 MW of the distributed assets are mechanically complete and were funded at financial close, while the remaining projects will be funded upon completion through year-end.
CRNC VWAGY

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08:08 EDT Cerence selected by Banma to bring conversational AI to China's OEMs - Cerence announced that Chinese smart car supplier Banma has tapped Cerence to bring advanced in-car conversational AI and voice recognition technology to Banma's automaker customers, including Shanghai Volkswagen Automotive, SVW, (VWAGY) and FAW-Volkswagen, FAW-VW. Banma provides smart car operating systems and digital transportation solutions for the automotive and transportation industries. By partnering with Cerence, Banma can deliver its key customers market-leading voice recognition and AI-powered, in-car intelligence solutions, enabling them to create unique and compelling brand experiences for drivers and passengers. Cerence offers broad language support across its solutions. Banma will be leveraging the Chinese, Cantonese and English language programs as it rolls out the technology to OEM customers. "Partnering with Banma is evidence of our continued expansion of strategic business partners in China and underscores the criticality of our multi-lingual capabilities and global support teams in bringing our innovations to drivers worldwide," said Bob Ligon, Chief Revenue Officer, Cerence. "SVW and FAW-VW are two of the largest OEMs in China, and we look forward to delivering technology that can help them make vehicles safer and more connected."
TAOP

Hot Stocks

08:08 EDT Taoping enters long-term strategic cooperation agreement with Wuxuan County - Taoping announced the company has entered into a long-term strategic cooperation agreement with Wuxuan County, Guangxi Province, with a potential market opportunity of $80M valuation for off-grid wastewater treatment solution alone. Under the Agreement, Taoping expects to provide customized intelligent, Cloud-based product solutions, including its exciting new Blue Box off-grid wastewater treatment solution, IoT Smart Rest Station, fully autonomous street sweeper and smart large screen displays. Wuxuan County is an important tourism city with an estimated 458,600 residents. By gaining access to Taoping's modular solutions, Wuxuan County's residents will be able to benefit from improved efficiency, convenience, and cost-effectiveness in various aspects of their daily lives. This follows news of Taoping's April agreement to provide similar services to China's Zhaoyuan City, which has more than 500,000 estimated residents.
ATY ILLM

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08:08 EDT AcuityAds announces full rebrand to illumin - AcuityAds Holdings has rebranded to illumin, the namesake of its revolutionary platform. As part of this rebranding, while the Company retains its legal name "AcuityAds Holdings Inc.", it will now be doing business as "illumin". The Company's new brand name reflects the platform's success and adoption in the market, and the company's mission to illuminate the path for brands to connect with their customers through the power of data-driven advertising. illumin's journey advertising platform enables brands and agencies to reach consumers at every stage of the marketing journey from awareness to conversion. Using an intuitive drag-and-drop interface, marketers can leverage advanced machine learning algorithms that let them deliver the right message at the right time on the right channels. The platform also provides full-funnel real-time data analytics and insights that help brands optimize their campaigns and drive measurable results. "We are thrilled to complete our transition to illumin and introduce even more marketers to our journey advertising platform," said Tal Hayek, CEO of illumin. "As consumer needs evolve it's essential for brands to have a holistic view of their customers' journeys and the ability to evolve and pivot their campaigns alongside changing consumer behavior. illumin lets marketers engage with their customers in a meaningful way at every touchpoint, whether that be through display advertising, native ads, digital-out-of-home, or many other digital formats in between. Our platform empowers brands and agencies, letting marketers think outside of traditional line items and execute their campaigns the way they originally envisioned them."
DMGGF

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08:07 EDT DMG Blockchain Solutions purchases new bitcoin miners - DMG Blockchain Solutions announces new miner purchases. These purchases are additive to its previously announced 1 EH/s of Bitcoin miner purchases, all of which have been delivered except its final tranche of 300 Bitmain S19 XPs. The purchases include 350 Bitmain S19 Pro, 350 Bitmain S19 XP and 850 Bitmain S19j Pro+ miners, which total an additional 1,550 units contributing 188 PH/s. The 350 Bitmain S19 Pros were a spot deal and have already arrived; the remaining miners will be added in the coming months to the DMG's Christina Lake data center. The Company is discussing further purchases with Bitmain and other suppliers. The additional hashrate is subject to the receipt, installation, and operation of these additional miners. As previously announced, DMG has purchased over 40 megawatts of crypto mining containers. The company is now finalizing shipping logistics. The first containers are expected to arrive in early July 2023 and continue arriving through September 2023
DUOT

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08:06 EDT Duos Technologies receives $1.9M contract add-on for passenger rail client - Duos Technologies Group announced an award of $1.9M for the enhancement of a planned Railcar Inspection Portal system in the passenger transportation sector. This latest addition is part of a long-term installation of the Company's most advanced RIP system, which is designed to capture high-speed images of railcars at up to 125 miles per hour. The upgrade marks another milestone in Duos' commitment to providing advanced rail safety inspection solutions for its customers. "As we continue to build on our offerings, we are seeing increased interest and adoption from current customers who are wanting to upgrade their safety and compliance protocols," said Duos Chief Executive Officer Chuck Ferry. "In this particular case, the upgrades are a major enhancement to the overall performance of the vision-based systems and lighting conditions."
DOMH

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08:06 EDT Dominari Holdings unit acquires asset management team - Dominari Holdings announced that its wholly-owned subsidiary, Dominari Securities LLC, has added an asset management team that manages over $700M in client assets to its organization. This is the first significant acquisition since the division officially launched earlier this month after the purchase of the broker-dealer and registered investment adviser divisions of Fieldpoint Private Securities.
TRU

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08:05 EDT TransUnion partner with Datavant to provide patient journey insights, solutions - TransUnion announced it is leveraging its acquisition of Neustar to expand its partnership with Datavant, the leader in helping organizations securely connect health data, to offer de-identified patient insights and measurement solutions for HIPAA-focused healthcare brands. The partnership will enable Datavant's ecosystem of partners to connect to demographic data available in TruAudience, TransUnion's comprehensive suite of solutions. The integration will enable healthcare and pharmaceutical companies to improve customer outcomes across the full lifecycle of patient engagement, especially measurement of outreach effectiveness. "We are thrilled to enable TransUnion to connect their demographic and lifestyle data to healthcare data while Datavant software enables de-identification tools to help customers protect patient privacy," said Dan Scudder, Head of Ecosystem at Datavant. "Patient outcomes are highly impacted by their environment so this data is important for contextualizing the patient journey and enabling more effective efforts to reach patients in need."
LDOS

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08:05 EDT Leidos awarded a new prime contract from U.S. Marine Corps - Leidos was recently awarded a new prime contract to develop an uncrewed aircraft system that can autonomously resupply forward-deployed ground forces. The firm-fixed-price, multiple-award contract has a period of performance of 18 months to build a single prototype for the Marine Corps. Under the contract, Leidos will develop, deliver and demonstrate an autonomous medium unmanned logistics system - air prototype. The prototype will then be used to perform a logistics distribution mission at the tactical edge of the battlefield. The goal of the project is to demonstrate a prototype UAS that can carry a logistics payload between 300 and 600 pounds to a combat area with a radius of 25 to 100 nautical miles. The work will be performed at locations in Colorado, Ohio, Oregon, California, Nevada and Arizona.
TU

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08:05 EDT Flash Forest secures Series A financing from TELUS Pollinator Fund For Good - Flash Forest, a Canadian reforestation company that uses drones and technology to regenerate post-wildfire areas that are deemed too unsafe for human tree planters, announced the completion of an C$11.4 million Series A financing round. Climate change is accelerating the frequency and severity of wildfires and we are quickly losing one of our best mechanisms for combating it: trees. Earth loses an average of 26 million hectares of trees every single year. That's an area roughly the size of Mexico, lost annually. Over 30 per cent of this loss can be attributed to wildfires. This new investment, co-led by the TELUS Pollinator Fund for Good and OurCrowd, will support the development and expansion of Flash Forest's rapid post-wildfire reforestation solution through North America in the fight against climate change.
MDGL

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08:05 EDT Madrigal Pharmaceuticals receives BTD from FDA for Resmetirom - Madrigal Pharmaceuticals announced that resmetirom has received Breakthrough Therapy designation, BTD, from the U.S. Food and Drug Administration for the treatment of patients with NASH with liver fibrosis. The Company also announced that the outcomes portion of the Phase 3 MAESTRO-NASH biopsy trial has completed enrollment. Paul Friedman, M.D., Chief Executive Officer of Madrigal, stated, "The Breakthrough Therapy designation for resmetirom reflects the FDA's recognition of resmetirom's potential in the treatment of NASH as a serious, life-threatening condition and an important area of investigational drug development. It also reinforces our confidence in our regulatory strategy as we approach the new drug application (NDA) filing for resmetirom, which remains on track for Q2 2023. The filing is supported by the positive outcomes on reduction of liver fibrosis and resolution of NASH from the 52-week serial liver biopsy portion of MAESTRO-NASH."
EVAX

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08:04 EDT Evaxion Biotech announces promising data for DNA-based cancer immunotherapy - Evaxion Biotech presented promising clinical data from its Phase 1/2a first-in-human study of its DNA-based personalized cancer immunotherapy, EVX-02 in combination with the checkpoint inhibitor nivolumab. Data were presented in the Late Breaking Research: Clinical Research 2 session at the 2023 AACR meeting in Orlando, Florida. The study, in patients with resected melanoma, showed that: All 10 patients who received the full dosing schedule of 8 immunizations with EVX-02 were relapse-free at their last assessment; Of these 10 patients, 9 completed the full study and were relapse-free at the 12-month end of study visit. One patient was prematurely terminated due to non-EVX-02 related adverse events, and was relapse-free at the last visit at 9 months; The combination of EVX-02 and nivolumab was well tolerated and only mild EVX-02-associated AEs were observed; Robust and long-lasting neoantigen-specific T-cell immune responses were confirmed in all EVX-02 completers; The induced T-cell immune responses involved both CD4+ and CD8+ T cells
ASMB

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08:03 EDT Assembly Biosciences announces additional data from Phase 1a trial on ABI-4334 - Assembly Biosciences provided an update of results from the final multiple-dose cohort in the ongoing Phase 1a study of its investigational next-generation, highly potent hepatitis B virus core inhibitor, ABI-4334, and announced it will evaluate partnering opportunities for its core inhibitor portfolio and prioritize its expanded virology pipeline. "We are encouraged by the promising clinical profile of our most potent core inhibitor candidate, 4334, and its potential to reach the clinical exposures needed for both potent antiviral activity and inhibition of cccDNA formation," said Jason Okazaki, chief executive officer and president of Assembly Bio. "While we are enthusiastic about these results and the antiviral activity shown in our Phase 1b study of our other next-generation core inhibitor, 3733, in HBV patients, we recognize that demonstrating the ability of next-generation core inhibitors to inhibit cccDNA formation in the clinic, which we view as a critical part of HBV cure, will require longer-duration Phase 2 studies. Because of this, we believe partnering our core inhibitor portfolio would enable additional opportunities for further clinical development for this compelling mechanism aimed at achieving a functional cure for HBV, including opening up other avenues for combination approaches." Assembly Bio's expanded virology research pipeline unveiled in 2022 focuses on differentiated programs against validated clinical targets for HBV/hepatitis delta virus and herpesviruses. With the reprioritization of programs, Assembly Bio's estimated cash runway extends into the third quarter of 2024. 4334 Clinical Data and Development Update: The Phase 1a clinical trial for 4334 is a randomized, blinded and placebo-controlled study evaluating the safety, tolerability and pharmacokinetics of 4334 following single ascending dose and multiple ascending dose administration in healthy subjects. Dosing has been completed for all subjects in all four single-dose cohorts , two multiple-dose cohorts of 100 mg and 200 mg and one food effect cohort at 200 mg. Based on data available for the single-dose and multiple-dose cohorts through April 17, 2023, 4334 continued to show a half-life supportive of once-a-day dosing.
SNCE

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08:00 EDT Science 37 appoints Irena Lambridis global head of quality assurance, compliance - Science 37 Holdings announced the appointment of Irena Lambridis as its Global Head of Quality Assurance & Compliance. Irena will be responsible for overseeing quality and compliance across all functions, including the Company's newly announced global Centers of Excellence in India, Pakistan, and Slovakia Irena brings nearly two decades of experience in clinical research quality assurance, having held senior leadership positions at KCR and Novella Clinical .
RIDE

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07:56 EDT Lordstown enters agreement with Amerit Fleet Solutions for service, warranty - Lordstown Motors and Amerit Fleet Solutions entered into an agreement for Amerit to provide service and maintenance to Lordstown's commercial fleet customers. The Lordstown Endurance began commercial production at the Foxconn EV Ohio assembly plant in Q3 2022. Sales started in Q4 2022. Production and deliveries resumed in April 2023 after a pause earlier in the year to address supplier quality issues and are expected to continue at a very low pace. Under the terms of the agreement, the two companies will jointly provide EV service and warranty for the Lordstown Endurance in key states allowed by law, as well as future vehicles developed by Lordstown in collaboration with the Foxconn EV ecosystem. Amerit is executing plans for the strategic rollout of service locations aligned with Lordstown's launch plan for initial fleet customers. Prior to the launch of services, Amerit service technicians will complete an extensive safety training program as well as Lordstown's training curriculum for the Endurance and other future vehicles.
ITAQ

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07:48 EDT Lakeview RNG acquires Oregon clean fuels assets, terms not disclosed - Lakeview RNG, a wholly owned subsidiary of NEXT Renewable Fuels, has acquired assets associated with the Red Rock Biofuels development in Lake County, OR effective Friday, April 14, 2023. Lakeview RNG is commencing a redevelopment plan focused on completing construction of certain aspects of the site while replacing or enhancing others. When complete, the Lakeview RNG facility is expected to be capable of converting forest waste into renewable natural gas and clean hydrogen. Lakeview RNG will use wood waste, or "slash," as the feedstock. Wood waste can come from activities like forest thinning, logging, and wildfire management activities on private and state lands. Today, that waste is largely burned in open slash piles, and the subsequent black carbon lands in rivers, on snowpack, and in the community's lungs. Instead, Lakeview RNG will process that wood waste and turn it into a low-carbon gaseous fuel, benefitting environmental and community health in southern Oregon and beyond. Lakeview RNG has evaluated the potential feedstock supply in Oregon and determined that all of its wood waste needs could come from within 150 miles of the facility. Wood waste used at the facility will be certified and compliant with applicable regulations for RNG production. Converting forest waste to renewable fuel products helps reduce forest fire fuel loads and provide an additional revenue source to timber communities. The local distribution network in Lake County is anchored by the Ruby pipeline and can deliver renewable fuels to transportation markets in Oregon and along the west coast. The purchase price of the facility has not been disclosed.
FRFHF

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07:46 EDT Fairfax Financial provides preliminary estimate on effect of IFRS 17 - Fairfax Financial Holdings announces its preliminary, not finalized, unaudited estimate of the effect of IFRS 17, the new accounting standard which was required to be adopted on January 1, 2023 for insurance contracts, on common shareholders' equity as at December 31, 2022. The finalized information will be presented in the Company's 2023 first quarter unaudited financial results, which will be released after the close of markets on Thursday, May 11. The Company's preliminary estimate of the effect of IFRS 17 on common shareholders' equity is that it will increase common shareholders' equity as at December 31, 2022 by approximately $2.2 billion, primarily reflecting the introduction of discounting net claims reserves, partially offset by the tax effect of the measurement changes and other of approximately $0.8 billion. Although IFRS 17 brings considerable changes to the measurement, presentation and disclosure of the Company's insurance and reinsurance operations, it will not affect the Company's underwriting strategy, its prudent reserving, management's use of the traditional performance metrics of gross premiums written, net premiums written and combined ratios, or the amount of the Company's cash flows.
PTN

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07:39 EDT Palatin's Melanocortin demonstrates therapeutic effects in diabetic retinopathy - Palatin Technologies announced The International Journal of Molecular Sciences published a manuscript that summarizes data demonstrating the effects of PL8331 in two mouse models of retinal disease, experimental autoimmune uveoretinitis - EAU - and diabetic retinopathy - DR -. Palatin and the National Institute of Health and the Massachusetts Lions Eye Research Foundation provided funding for the study. Both models evaluated the efficacy of PL8331 as an agonist at the melanocortin 1 and melanocortin 5 receptors. In the EAU mouse model, PL8331 treatment resulted in resolution of inflammation and preservation of retinal structure. Specifically, PL8331 protected the retinal photoreceptors from the auto-inflammatory damage that normally occurs in the EAU model. In the DR mouse model, PL8331 treatment resulted in enhanced survival of various types of retinal cells and the suppression of vascular endothelial growth factor. In addition, the retinal pigmented epithelial cells were able to maintain their normal anti-inflammatory activity. The findings from both studies clearly demonstrate the importance of the melanocortin system in protecting the eye from the damage caused by pathological inflammation and support the potential of melanocortin agonists as treatments for various retinal diseases.
JUSHF

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07:38 EDT Jushi announces support for Virginia's passage of medical cannabis bills - Jushi Holdings announced support and appreciation for the Virginia General Assembly's passage of medical cannabis and cannabinoid product-related bills amended by Governor Glenn Youngkin. Last week, the Virginia General Assembly gathered to take up seventy-eight bills amended by the Governor, including medical cannabis bills designed to enhance program accessibility for patients, improve operational efficiency for pharmaceutical processors and fully transfer regulatory oversight to the Virginia Cannabis Control Authority. Most patient-focused and operations-based changes will become effective on July 1, 2023, and CCA will take over regulating the program on January 1, 2024. With respect to broader cannabis-related matters, the General Assembly also approved Governor Youngkin's amendments to bills aimed at bringing unauthorized, intoxicating cannabinoid products under a regulatory framework. These products are easily accessible in every community across the Commonwealth and commonly used as a substitute for adult-use cannabis. Currently, these products are not subject to regulatory oversight or consumer safety protections and have seriously sickened many Virginians - including hundreds of young children. "While we support the intention of this legislation to protect public health and safety, Jushi respectfully maintains that any effort to improve the status quo that does not incorporate a retail adult-use cannabis market will ultimately be ineffective," said said Jim Cacioppo, Chief Executive Officer, Chairman and Founder of Jushi Holdings Inc. "We are disappointed Virginia missed an opportunity to advance bills expanding legal access to safe, tested adult-use cannabis products this Session, but appreciate that this year's cannabinoid product-related bills represent a step in the right direction for Virginians," Cacioppo said.
AMST

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07:36 EDT Amesite demonstrates AI content generation with AI narration on V6 platform - Amesite announces the demonstration of AI generated content with AI narration capabilities on its recently launched Version 6.0 platform, complementing its recent GPT-4 integration. The capabilities, demonstrated in Amesite's free-to-the-public course on ChatGPT, demonstrate how content can be created with high efficiency and scalability, along with purpose-built, AI-driven features to support user learning.
DFLI

Hot Stocks

07:35 EDT Dragonfly Energy enters battery partnership with Airstream - Dragonfly Energy announced it has partnered with Airstream, the manufacturer of the iconic riveted aluminum travel trailers, to provide Battle Born Batteries as standard equipment in the Pottery Barn Special Edition Travel Trailer and Classic Travel Trailer models and as an optional upgrade on the REI Co-op Special Edition Basecamp Travel Trailer. Battery anxiety has long been a pain point amongst consumers in the RV Industry, however with this power upgrade from Dragonfly Energy, Airstream customers now have access to a solution that allows them to enhance their camping experience. "We are honored to see our lithium power solutions as both standard and factory-installed upgrades on such an iconic brand," Dr. Denis Phares, CEO of Dragonfly Energy, said. "We are excited about the collaborative opportunities that our expanded partnership will enable in the future. And I would also like to thank Airstream for recognizing all of the hard work put forth by our employees and suppliers by naming us a Five Rivet Supplier."
LI

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07:35 EDT Li Auto unveils autonomous driving, BEV roadmap - Li Auto hosted a press briefing to unveil its autonomous driving and BEV roadmap at the 20th Shanghai International Automobile Industry Exhibition. In terms of autonomous driving, the Company expects to release its city NOA for beta testing in its full-stack self-developed Li AD Max 3.0 in the second quarter of 2023, and targets to roll out in 100 cities nationwide by the end of 2023. The Company believes that the Li AD Max 3.0 will be able to function without high-precision maps and, more importantly, to perceive, decide, and plan in real time like a human driver. In addition, Li Auto introduced its 800-volt fast charging solution, which allows its BEVs to achieve a driving range of 400 kilometers with just a 10-minute charge, aiming to offer an energy replenishment experience as efficient as ICE vehicle refueling. Opening a new chapter through its paralleled development of EREVs and HPC BEVs, the Company strives to establish a model portfolio of one super flagship vehicle, five EREVs, and five HPC BEVs by 2025. The Company's BEV solution includes an 800-volt electric drive system based on the third-generation silicon carbide power module, batteries with 4C charging capabilities, a wide temperature range thermal management system, and a fast charging network. The Company also announced a comprehensive strategic cooperation agreement with Contemporary Amperex Technology. The Company currently expects that its inaugural BEV will become the world's first mass-produced model equipped with CATL's 4C-rate Qilin batteries. With respect to the fast charging network, the Company endeavors to build over 300 charging stations along highways by the end of 2023, covering four major economic zones including the Beijing-Tianjin-Hebei region, the Yangtze River Delta region, the Great Bay Area, and the Chengdu-Chongqing region. The Company will strive to expand its charging network to 3,000 charging stations by 2025.
LMT

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07:35 EDT Lockheed Martin backs FY23 cash from operations greater than, equal to $8.15B - Backs FY23 free cash flow greater than, equal to $6.2B.
QLGN

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07:34 EDT Qualigen Therapeutics presents data on QN-247 at AACR meeting - Qualigen Therapeutics announces data from the Company's poster presented at the American Association for Cancer Research, AACR, Annual Meeting 2023 held April 14-19 in Orlando, FL. The Company presented in vivo efficacy data regarding its QN-247 program, for which it is actively seeking partners. "These encouraging data demonstrate QN-247 may be an effective nano-immunotherapy against triple negative breast cancer. They are an important validation for our development approach, and we believe they will be meaningful as we actively seek opportunities around this compound," said Michael Poirier, Qualigen's Chairman and CEO. Highlights from QN-247 Poster: Study authors had prepared QN-247 conjugates that build upon the legacy of the anti-proliferative DNA aptamer AS1411. . QN-247 is active in vitro against a variety of cancers including prostate cancer and Triple Negative Breast Cancer, and more potent than the anti-proliferative aptamer AS1411 itself. In addition, QN-247 is effective in vivo against a xenograft mouse TNBC model showing highly significant reductions in tumor volumes with no evidence of toxicity.
LMT

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07:33 EDT Lockheed Martin reports Q1 cash from operations of $1.6B; free cash flow $1.3B
OPGN

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07:33 EDT OpGen submits De Novo request to U.S. FDA for Unyvero UTI panel - OpGen announced that it has submitted a De Novo classification request to the U.S. Food and Drug Administration, FDA, seeking marketing authorization for its Unyvero UTI Urinary Tract Infection panel, following successful completion of its clinical trial. OpGen's Unyvero UTI Panel tests for a broad range of bacterial and fungal pathogens as well as antimicrobial resistance markers directly from urine specimens. The test aims at quantitative detection of microorganisms. The trial was designed to compare the performance of the Unyvero UTI Panel for detecting urinary tract infections against various reference tests, using clean-catch or catheter related urine samples. Across all prospectively enrolled samples, the primary study endpoint was successfully met by demonstrating an overall weighted average sensitivity of 96.8% and overall weighted average specificity of 97.4% when compared against each trial site's standard of care microbiology results. Since completion of enrollment, OpGen has performed testing of contrived samples with well characterized strains to provide additional data for low-prevalence strains and antibiotic resistance markers at its facility in Germany and generated next-generation sequencing (NGS) data at its Rockville, Maryland, lab facility to establish genotypic correlation of antibiotic resistance markers detected during the study. "Following the in-depth analysis of all of our clinical trial data, we have compiled a comprehensive submission package for our De Novo classification request, building on a large data set of Unyvero data and multiple reference methods," explained Johannes Bacher, Chief Operating Officer of OpGen. "This marks a major milestone, and we're looking forward to working closely with the FDA during the interactive review for the Unyvero UTI panel, which we hope to become the first high multiplex molecular diagnostic IVD for urine samples granted by the FDA."
INBS

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07:33 EDT Intelligent Bio Solutions secures UK patent for Intelligent Fingerprinting tech - Intelligent Bio Solutions announced that the Company has been granted a patent in the United Kingdom (UK) relating to its Intelligent Fingerprinting Drug Screening System DSR-Plus Cartridge Reader. This is the Company's 13th patent, which further strengthens the protection of its unique and proprietary drug screening technology. UK Patent No: GB2592432, relates to the proprietary lateral flow test strip reading capability within the Company's latest DSR-Plus cartridge reading unit. Designed and manufactured in the UK, the cartridge reader features a compact and portable specification that enables even simpler and faster drug testing. It provides organizations with rapid drug screening support wherever and whenever it's needed. The DSR-Plus reader has been designed with no moving parts, ensuring resiliency when customers transport it between different sites, while improved battery life boosts screening productivity for human resources teams. The non-invasive Intelligent Fingerprinting system comprises a small, tamper-evident drug screening cartridge onto which ten fingerprint sweat samples are collected in under a minute, before the portable DSR-Plus reader provides an on-screen result in less than ten minutes. The system can be used in-house and screens the sweat for recent drug use, including cannabis, cocaine, opiates, and methamphetamine.
PHIO

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07:32 EDT Phio Pharmaceuticals' Intasyl platform shows anti-tumor efficacy - Phio Pharmaceuticals announced that in vivo data from a mouse model of colon cancer demonstrates target synergy-enhanced anti-tumor efficacy from a novel dual-targeting mouse PD-1 and CTLA-4 of an INTASYL coformulation using the company's proprietary Intasyl RNAi platform. Intratumoral administration of the PD-1/CTLA-4 Intasyl improved tumor control compared to either single targeting formulation, at an identical total dose. The dual-targeting formulation was well tolerated. "The synergistic effects of dual inhibition of PD-1 and CTLA-4 in enhancing tumor response are clinically recognized, however, a high rate of immune-related adverse events limits the utility of systemic use of this combination of products," said Mary Spellman, Acting Chief Medical Officer. "Intratumoral administration of dual-targeting PD-1/CTLA-4 Intasyl may provide an effective treatment option, with an improved safety profile."
GS

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07:30 EDT Goldman Sachs reports Q1 FICC revenue $3.93B, down 17% y/y
GS

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07:30 EDT Goldman Sachs reports Q1 Global Banking & Markets revenue $8.44B - Global Banking & Markets generated quarterly net revenues of $8.44B, driven by strong performances in Fixed Income, Currency and Commodities and Equities, including record quarterly net revenues in Equities financing. Asset & Wealth Management generated quarterly net revenues of $3.22B, including record Management and other fees. Platform Solutions generated quarterly net revenues of $564M, more than double the amount in the prior year period.
WLDPF

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07:29 EDT Wildpack Beverage announces late filing of annual financial statements - Wildpack Beverage announced the Company's potential delay in filing its annual financial statements for the year ended December 31, 2022 and related management discussion and analysis and certifications, and the CEO and CFO certificates delating to the Financial Statements beyond the prescribed filing deadlines. The Company's potential delay in filing its Required Filings on time is due to the Company's recent change of auditor, whereby a successor auditor has not yet been appointed. The Company is in the process of appointing a successor auditor, and upon appointment of such successor auditor the Company intends to promptly coordinate the financial audit of its annual financial statements and associated filings with the successor auditor. Considering the foregoing, it is the Company's view that should the Required Filings not be filed by May 1, 2023, then, the present circumstances warrant the imposition of a management cease trade order as contemplated under National Policy 12-203 - Management Cease Trade Orders. The Company has applied for a MCTO, however there is no assurance that it will be granted. The Company's board of directors and its management are working expeditiously to meet the Company's obligations to file the Required Filings. The Audit Committee is working diligently to appoint a successor auditor, and to work with such successor auditor to complete the Financial Statements. The Company expects to be in a position to issue and file the Required Filings by no later than June 30, 2023. Until then, the Company has confirmed that it intends to satisfy the provisions of the alternative information guidelines described in sections 9 and 10 of NP 12-203 for so long as it remains in default for failure to file the Required Filings. Should the Company fail to file the appropriate Default Status Reports as prescribed by NP 12-203, the securities commissions or regulators may, as a result of such failure, impose an Issuer Cease Trade Order. The Company confirms that it is not subject to any insolvency proceeding as of the date hereof. The Company also confirms that there is no other material information concerning the affairs of the Company that have not been generally disclosed as of the date herein.
GS

Hot Stocks

07:28 EDT Goldman Sachs reports Q1 annualized ROE 11.6%, ROTE 12.6% - Book value per share was $310.48.
LASE

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07:16 EDT Laser Photonics receives order from Gateway Clipper - Laser Photonics announced it received an order from Gateway Clipper, an operator of sightseeing and dinner cruises on Pittsburgh's Three Rivers.
IDR

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07:16 EDT Idaho Strategic begins drifting on high-grade H-Vein - Idaho Strategic Resources is pleased to announce an exploration crosscut intercepted the "H-Vein" at the Golden Chest Mine on March 29th, cutting a strongly mineralized vein that assayed 32.1 grams per tonne gold over 0.43 meters on the northern rib and 54.1 gpt over 0.72 meters on the southern rib. Both samples represent true thickness. The H-Vein lies 60 meters west of the Idaho Vein at the 794 elevation in the hangingwall of the Idaho Fault, which is why it is referred to as the H-Vein. The H-Vein is a banded quartz vein known to lie immediately below the Timber King Fault. Both fault and vein zone strike northerly and dip from 70 to 75 degrees to the west. Previous drilling by IDR had identified this vein zone when drilling for targets along the Idaho Vein. This vein system consists of both a banded quartz vein as well as the adjacent silica-flooded zone bearing strong pyrite. The banded vein exhibits abundant visible gold with associated pyrite, galena, chalcopyrite, and sphalerite. IDR's chip samples of the banded vein show assay values ranging between 29 gpt to 73.7 gpt gold. Widths of this banded vein are from 0.4 to 0.72 meters. The adjacent silica-flooded unit is hard, dark-colored and has 3-5 % auriferous pyrite. Muck samples are collected from each 2.5 m long round during drifting and are anticipated to be representative of the diluted grade that can be expected at the mill. Initial drifting along the vein has yielded an average muck sample grade of 25.1 gpt for 24.8 meters of strike length. The H-Vein material is currently being shipped to the mill so the gold grade of the muck samples can be confirmed.
ACHFF

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07:13 EDT Arch announces results of dose escalation human trial for LSALT peptide - Arch Biopartners announced that it has safely increased the maximum daily dose of LSALT peptide to 20 mg per day in healthy, normal volunteers in a recently completed human trial in Australia. LSALT peptide is the Company's lead drug candidate for treating inflammation in the lungs, liver and kidneys and Arch intends to use the new maximum dose in designing a Phase II trial targeting cardiac surgery-associated acute kidney injury. The new safety data will be included in an Investigational New Drug Application to the U.S. FDA, to be submitted in relation to the CS-AKI trial in due course. The dose escalation human trial was performed at the Alfred Hospital in Melbourne, Australia.
ENVX

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07:12 EDT Enovix announces pricing of $150M offering of convertible senior notes - Enovix Corporation announced the pricing of $150.0 million aggregate principal amount of 3.00% Convertible Senior Notes due 2028 in a private placement to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended and in a concurrent private placement under Section 4(a)(2) of the Securities Act. An entity affiliated with Thurman J. Rodgers, Chairman of Enovix, has agreed to purchase $10.0 million aggregate principal amount of the Notes in the concurrent private placement. The Notes purchased in the concurrent private placement are referred to as the "Affiliate Notes." In addition, an entity affiliated with John Doerr, Chairman of Kleiner Perkins, has agreed to purchase $10.0 million aggregate principal amount of the Notes in the Offering. Mr. Rodgers and Mr. Doerr have previously co-invested in various companies, including Enphase Energy, Inc.
XOM

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07:11 EDT Sintana provides update on VMM-37 joint operating agreement - Sintana Energy reports that ExxonMobil sent Patriot Energy Oil and Gas, a subsidiary of the Company, a notice stating that, based on the terms of the Joint Operating Agreement between ExxonMobil and Patriot, it had decided to withdraw from the JOA as of May 31, 2023. The notice also states that ExxonMobil will withdraw from the Contract with the Agencia Nacional de Hidrocarbons, effective after obtaining required Government approvals. Both the JOA and Contract pertain to the 43,158 acres property known as the VMM-37 block which is in Colombia's Middle Magdalena Valley Basin. The Company fully reserves its rights under the contracts governing VMM-37 and applicable laws and regulations.Further updates will be provided with respect to these matters as additional information becomes available.
CLSD

Hot Stocks

07:11 EDT Clearside Biomedical announces plans for ODYSSEY phase 2b trial of CLS-AX - Clearside Biomedical, announced today plans for ODYSSEY, a randomized, double-masked, parallel-group, active-controlled, multi-center Phase 2b clinical trial of CLS-AX using suprachoroidal delivery in neovascular age-related macular degeneration. The Company plans to open the trial for enrollment this quarter and expects topline results in Q3 2024. George Lasezkay, Pharm.D., J.D., Clearside's President and Chief Executive Officer, commented, "We are excited to advance our CLS-AX program, building on the positive data from our OASIS Phase 1/2a trial, which showed that CLS-AX was well tolerated and demonstrated an excellent safety profile and promising data up to 6 months durability. We believe CLS-AX has the potential to reduce treatment burden in patients with wet AMD while maintaining visual acuity... we believe that our team has optimized the trial design to efficiently provide the necessary data to design the Phase 3 program. ODYSSEY will enroll treatment-experienced participants with wet AMD and use aflibercept, a current standard of care, as the comparator, over 36 weeks of treatment. We expect ODYSSEY topline results in Q3 2024," concluded Dr. Lasezkay
TLRY

Hot Stocks

07:09 EDT Tilray launches PROJECT 4:20, new limited release craft beer - Montauk Brewing announced the launch of PROJECT 4:20, a new limited release craft brew created to celebrate and support local green charities during Earth Month and beyond. Montauk Brewing also invites fans to celebrate the launch of PROJECT 4:20 at the Brew Barn in Montauk, New York, on April 20, 2023. Vaughan Cutillo, Founder, Montauk Brewing Company, said, "As a true Montauk brand, we wanted to create something new that purely focused on supporting our passion for the ocean, environment, and local communities. PROJECT 4:20 is a new and important initiative for us that we are extremely proud of and plan to launch beyond the northeast and across the country."
BCRX

Hot Stocks

07:08 EDT BioCryst announces $450M financing commitment from Pharmakon - BioCryst Pharmaceuticals announced that the company has secured $450 million in committed financing from funds managed by Pharmakon Advisors, LP. BioCryst has elected to draw $300 million of the $450 million available to the company on the closing date. The remaining $150 million of committed capital can be drawn at the company's option until September 2024. Net proceeds to the company at closing will be approximately $26 million following the repayment of its existing credit facility with Athyrium Capital Management, and fees and expenses associated with the transaction. The new five-year credit facility bears interest at the 3-month Secured Overnight Financing Rate + 7.00%. BioCryst has the option to pay up to 50% of the interest on the loans advanced on the closing date in-kind for the first six quarters of the term, allowing the company to defer cash interest payments until after this period. The facility contains no scheduled amortization payments, with all outstanding principal due at the maturity date in 2028. There are no financial covenants associated with the financing.
IMCR

Hot Stocks

07:08 EDT Immunocore presents new KIMMTRAK data on association between ctDNA, survival - Immunocore has presented four posters with KIMMTRAK data in HLA-A*02:01 patients with metastatic uveal melanoma, at the 2023 American Association for Cancer Research Annual Meeting 2023. Circulating tumor DNA reduction by week 9 was observed in 88% of mUM patients treated as first-line and 71% in previously treated patients; in both trials, this reduction was associated with longer overall survival. ctDNA clearance was also higher in first-line patients compared to second-line patients. ctDNA clearance in the Phase 3 trial was associated with 84% 1-year OS. The final analysis from the Phase 2 trial in previously treated mUM, after 46 months of follow-up, showed a median OS of 16.8 months - consistent with previous data updates. The landmark OS rates from the trial were approximately double historical rates in this patient population, as reported in two meta-analyses. The third poster provides a pooled analysis from 3 clinical trials in 12 mUM patients with orbital disease. Tebentafusp demonstrated preliminary signals of activity in intra-ocular lesions, supporting KIMMTRAK's use in patients with unresectable uveal melanoma. The fourth poster shares in vitro data potentially explaining how tebentafusp may lead to OS benefit even in tumors with heterogenous gp100 expression.
BABYF

Hot Stocks

07:07 EDT Else Nutrition rolls out Toddler, Kids Shake SKUs to Canada retailer - ELSE NUTRITION HOLDINGS rolled out Toddler and Kids Shake SKUs to Canada's largest retailer at over 440 locations nationwide as of March 2023.
SURF

Hot Stocks

07:06 EDT Surface Oncology presents new preclinical data on SRF114 - Surface Oncology announced the presentation of new preclinical data for SRF114, a fully human anti-CCR8 antibody, at the American Association for Cancer Research, AACR, Annual Meeting 2023 in Orlando, Florida. The data will be presented in a poster session being held today. Summary of key data: In human CCR8 knock-in mice, SRF114, a fully human antibody targeting human CCR8, conferred robust anti-tumor activity and reshaped the tumor microenvironment towards a proinflammatory milieu. In different in vivo models, SRF114 monotherapy or treatment with a murine surrogate antibody promoted expansion of CD8+ effector T cells and increased the production of pro-inflammatory molecules including IFNgamma, TNFalpha, and granzyme A in a checkpoint-resistant tumor model. Anti-CCR8 therapy resulted in depletion of tumor Tregs without impacting peripheral lymphoid Treg cell populations and led to increases in the levels of co-stimulatory molecules CD80 and CD86 in a subset of tumor myeloid cells. Anti-CCR8 and anti-PD-1 combination therapy increased tumor immune cell infiltration, cytokine production and improved overall survival in a checkpoint inhibitor resistant melanoma model.
GP

Hot Stocks

07:06 EDT GreenPower Motor deploys Round 5 of EV school buses project in West Virginia - GreenPower Motor announced the deployment of Round 5 of its all-electric school buses Pilot Project in Calhoun, Putnam and Roane County school districts in West Virginia. New for the first time, Upshur County, will continue to pilot the Nano BEAST making it the first school district during the project to use the school bus past the six-week mark.
SEOVF

Hot Stocks

07:05 EDT Sernova says proxy advisory firms recommend shareholders vote for nominees - Sernova announces that a second independent, third-party proxy advisory firm, Glass Lewis & Co. has recommended Sernova's shareholders vote FOR all of Sernova's management nominees using only management's WHITE proxy. Glass Lewis also recommended that shareholders vote FOR the appointment of KPMG LLP as Sernova's auditors and FOR the resolution to amend the Corporation's stock option plan and DSU Plan. Glass Lewis recommended that shareholders vote FOR the resolution to amend the Corporation's stock option plan and DSU Plan, as the proxy advisory firm believes the terms of the plan are in line with the majority of similar equity-based plans of TSX issuers. Glass Lewis' view is that the plan will serve to strengthen the alignment of company and shareholder interests. The Corporation believes that encouraging its executive officers, senior management and employees to become shareholders is the best way of aligning their interests with those of its long-term shareholders. As a result, executive officers management and employees are provided with the opportunity to participate in the appreciation of the Corporation's share price, through Sernova's equity compensation incentive plan.
KRYS

Hot Stocks

07:05 EDT Krystal Biotech doses first subject in Phase 1, cohort 3 study of KB301 - Jeune Aesthetics, a wholly-owned subsidiary of Krystal Biotech, announced treatment of the first subject in the Phase 1, Cohort 3 study of KB301 for the improvement of lateral canthal lines at rest. Jeune's lead product candidate, KB301, delivers the human COL3A1 gene to targeted skin cells that in turn produce natural type 3 collagen. The Phase 1, Cohort 3 study is being conducted at a single center as an open label study to evaluate two different doses of KB301 in up to 20 subjects. Improvement of lateral canthal lines at rest was selected as a target indication for KB301 based upon the Phase 1 safety, efficacy and durability studies, which evaluated KB301 in the lower and upper cheek, including the lateral canthal region. Subjects will be followed for three months after KB301 treatment, and the study is expected to be completed in 2H 2023.
XERS

Hot Stocks

07:05 EDT Xeris Biopharma announces issuance of U.S. patent covering XeriSol formulations - Xeris Biopharma Holdings announced that the U.S. Patent and Trademark Office has issued US Patent Number 11,590,205, entitled 'METHODS FOR PRODUCING STABLE THERAPEUTIC GLUCAGON FORMULATIONS IN APROTIC POLAR SOLVENTS.' The claims in this newly issued patent cover certain pharmaceutical formulations in Xeris' Gvoke product line, methods of use of such formulations in treating hypoglycemia, and methods of manufacturing the therapeutic formulations. "Xeris' strategy is to patent early and often, including through a castle/moat approach that has led to numerous filings both at the platform and product levels. The addition of this new patent further strengthens our intellectual property position in the XeriSol platform portion of our portfolio and has claims that will cover the Gvoke formulation, which is in all our currently marketed Gvoke products," said Paul R. Edick, Xeris' Chairman and CEO. The Xeris patent portfolio consists of 178 total patents globally, of which 33 are U.S. issued; 128 patent applications pending globally, of which 21 are pending in the U.S.; and 60 patents pertaining to its technology platform. Xeris' XeriSol patent portfolio includes patents and applications directed to this platform formulation technology, commercial and pipeline pharmaceutical product formulations, and therapeutic methods using such formulations to treat a variety of human diseases and disorders. All patents are owned by Xeris Biopharma subsidiaries.
CLWT

Hot Stocks

07:05 EDT Euro Tech Holdings announces $300,000 share repurchase program - Euro Tech Holdings announced that its Board of Directors has approved a program to repurchase up to 230,000 shares of its issued and outstanding ordinary shares for an aggregate purchase price of up to $300,000. This gives the company the ability to repurchase its shares in the open market or through negotiated or block transactions from time to time based on market and business conditions over the next 12 months.
SLCA

Hot Stocks

07:03 EDT U.S. Silica announces price increases on Industrial and Specialty Products - U.S. Silica Holdings announced that its Industrial and Specialty Products segment will increase prices for most of its non-contracted products used primarily in glass, filtration, foundry, paints, coatings, elastomers, roofing, chemicals, recreation, building products and other applications. Price increases will range up to 20% depending on the product and grade and go into effect for shipments beginning June 1. These price increases are necessary to help offset significant and continuing cost increases in labor, transportation, materials and manufacturing costs.
PSTV

Hot Stocks

07:03 EDT Plus Therapeutics completes Phase 1/ Part A of ReSPECT-LM trial - Plus Therapeutics announced the completion of Cohort 3 of the ReSPECT-LM Phase 1/2a dose-escalation clinical trial of rhenium obisbemeda for the treatment of leptomeningeal metastases from solid tumors less than one month since its initiation, demonstrating rapid enrollment. Additionally, the Company has expanded the number of clinical trial sites to include Northwestern Memorial Hospital in Chicago, marking the first expansion of the ReSPECT-LM trial beyond Texas. Thus far, 10 patients have been treated across three cohorts in the ReSPECT-LM Phase 1/Part A dose escalation clinical trial. "We are excited to accelerate enrollment in our ReSPECT-LM clinical trial and look forward to working with our site partners to expand the reach of this study to new and existing patients, including our compassionate use program where we retreated a patient with LM who might benefit from this novel, well-tolerated therapy," said Norman LaFrance, M.D., Chief Medical Officer of Plus Therapeutics. "Throughout all three cohorts of this study, no dose-limiting toxicities have been observed with administered radiation doses of up to 26.4 millicuries, signaling the potential to maximize the potency of rhenium obisbemeda in order to effectively destroy tumor cells within the cerebrospinal fluid. We are preparing to reconvene with the U.S. Food and Drug Administration to provide data from Cohorts 1 through 3 and determine next steps for Part B of the Phase 1 trial."
ALKS

Hot Stocks

07:02 EDT Alkermes submits Form 10 to SEC for planned separation of oncology business - Alkermes announced that it has submitted a confidential draft Form 10 registration statement to the United States SEC in connection with the previously announced planned separation of the company's oncology business into an independent, publicly-traded company. The company continues to expect to complete the separation in the second half of 2023. As announced in November 2022, Alkermes' Board of Directors unanimously approved the exploration of separating the company's neuroscience business and oncology business. The planned separation is part of a strategic process commenced by the Board to unlock shareholder value through a sharpened strategic focus, simplified capital allocation decision-making, and distinctive investment profiles for each business.
TLSA

Hot Stocks

07:02 EDT Tiziana Life Sciences initiates program to develop foralumab in T1D - Tiziana Life Sciences announced that it is initiating a program to develop intranasal foralumab for the treatment or prevention of Type 1 Diabetes, T1D. "With the FDA approval of the humanized anti-CD3 mAb TZIELD and then its subsequent announced acquisition of Provention Bio by Sanofi for $2.9 billion, CD3 has emerged as an established and attractive target for Type 1 Diabetes," commented Gabriele Cerrone, Executive Chairman, Founder and interim Chief Executive Officer of Tiziana. "We believed that having a fully human CD3 antibody may offer benefits to patients across many different chronic disease indications."
SYAXF PLL

Hot Stocks

06:57 EDT Piedmont Lithium and Sayona Mining announce updated resources in Quebec - Piedmont Lithium's (PLL) joint venture partner, Sayona Mining (PLL), has released a definitive feasibility study for the jointly-owned North American Lithium project, and increased lithium mineral resources at its 60%-owned Moblan Lithium Project, both in the province of Quebec. Piedmont holds a 25% stake in NAL and an equity interest of approximately 14% in Sayona. The NAL DFS contemplates increased annual spodumene concentrate production averaging 190K metric tons per year over a 20-year mine life, with a target of 226K tpy in years one through four of steady state operations and approximately 186K tpy beginning in year five. The revised production targets resulted in an increase to the net present value for the NAL project compared to the prefeasibility study completed in 2022. The revised block model has resulted in a reduction in ore reserves and certain Indicated Resources have been reclassified as Inferred Resources. The study contemplates a mine life of 20 years, reduced from the prefeasibility study estimate of 27 years. Piedmont holds an offtake agreement with Sayona Quebec to purchase the greater of 113,000 tpy or 50% of the joint venture's spodumene concentrate production. Sayona Quebec is undertaking a prefeasibility study to explore downstream production at NAL and expects results in Q2. Separately, Sayona has announced a significant increase in mineral resources at its 60%-owned Moblan project in northern Quebec. Measured and Indicated Mineral Resources at Moblan now total 41.1 million metric tons @ 1.32% Li2O using a 0.55% Li2O cut-off grade.
AUMN

Hot Stocks

06:53 EDT Golden Minerals reports Q1 production from Rodeo mine - Golden Minerals reported production figures from its Rodeo gold-silver mine in Mexico for Q1. Summary highlights include: Payable gold production: 2,081 oz Au; Payable silver production: 111,535 oz Ag; Payable gold equivalent production: 2,219 AuEq oz; Average gold grade: 1.6 g/t Au; Gold recovery: 72.6%; silver recovery: 75.5%; realized gold/silver prices: $1,891/oz Au and $22.60/oz Ag in Q4.
EXK

Hot Stocks

06:52 EDT Endeavour Silver to proceed with underground mine, mill at Terronera Project - Endeavour Silver is pleased to announce the Board of Directors of the company has made the decision to proceed with the construction of an underground mine and mill at the Terronera Project in Jalisco state, Mexico. To date, the company made significant progress on development activities, with long-lead item procurement well advanced and a seasoned team of development personnel established on the ground. Additional activities include onsite delivery of mobile mining equipment, assembly of initial project infrastructure and advanced earthworks with commencement of underground mine access development.
AULT

Hot Stocks

06:47 EDT Ault Inc.: BITNILE.com surpassses 1M engaged users - Ault Alliance and BitNile Metaverse, the company operating the rapidly growing virtual world, BITNILE.com, announced that the Platform has surpassed 1M engaged users in less than seven weeks since launching its early-access phase.
BLU GSK

Hot Stocks

06:46 EDT GSK to acquire Bellus Health for $14.75 per share - GSK plc (GSK) and Bellus Health (BLU) announced that they have entered into an agreement under which GSK will acquire Bellus, a Canada-based, late-stage biopharmaceutical company working to better the lives of patients suffering from refractory chronic cough, or RCC, for $14.75 per share of common stock in cash representing an approximate total equity value of $2.0B, or GBP 1.6B. "The acquisition provides GSK access to camlipixant, a potential best-in-class and highly selective P2X3 antagonist currently in phase III development for the first-line treatment of adult patients with RCC," the companies stated. "The acquisition of BELLUS is highly synergistic with GSK's expertise in respiratory medicines and is further supported by GSK's leading R&D, manufacturing, and commercialisation capabilities. Following the anticipated regulatory approval and launch of camlipixant in 2026, the acquisition is expected to be accretive to adjusted EPS from 2027 and has the potential to deliver significant sales through 2031 and beyond," GSK said. "Under the terms of the agreement, the acquisition will be effected through a Plan of Arrangement pursuant to the Canada Business Corporations Act in which the shares of BELLUS outstanding will be acquired by the Company in consideration of US$14.75 per share in cash. Subject to customary conditions, including court approval, the approval of the acquisition by at least 66.67% of the votes cast at a meeting of BELLUS' shareholders and a majority of the votes cast by non-interested shareholders at such meeting, and approval by the appropriate regulatory agencies, the transaction is expected to close in the third quarter of 2023 or earlier. The per-share price represents a premium of approximately 103% to BELLUS' closing stock price on 17 April 2023 and a premium of approximately 101% to BELLUS' volume-weighted average price (VWAP) over the last 30 trading days. BELLUS' Board of Directors has unanimously recommended that BELLUS' shareholders vote in favour of the approval of the acquisition. GSK will account for the transaction as a business combination and expects it to be accretive to adjusted EPS in 2027, the expected first full year of camlipixant's sales. There is no change to GSK's full-year 2023 guidance or the medium-term outlook for 2021-2026 of more than 5% sales and 10% adjusted operating profit CAGR at CER," GSK added.
JNJ

Hot Stocks

06:39 EDT Johnson & Johnson raises quarterly dividend 5.3% to $1.19 from $1.13 per share - At the new rate, the indicated dividend on an annual basis is $4.76 per share compared to the previous rate of $4.52 per share. The next quarterly dividend is payable on June 6 to shareholders of record as of the close of business on May 23. The ex-dividend date is May 22.
AMPE

Hot Stocks

06:38 EDT Ampio CEO issues letter to stockholders regarding operational focus - Ampio released the following letter to stockholders from its chairman, Kevin Buchi and CEO, Mike Martino. The company said, "On March 28, 2023, we filed our 2022 Annual Report on Form 10-K. In this letter we would like to elaborate on two key operational points which were included in that Annual Report. Firstly, we want to elaborate on progress with the development of what we have previously called, "AR-300." We gained a considerable amount of knowledge about osteoarthritis (OA) from the company's previous clinical and in vitro studies with Ampion. In January 2022, we began work on "AR-300," a series of synthetic formulations of what we believed to be the three active pharmaceutical ingredients (APIs) that were present at low levels in Ampion. Our development efforts in the first quarter 2023 have focused on rigorously testing different formulations of these APIs at an independent, well-respected research organization, using two validated, well-published rodent models of OA, which we will highlight here. The first model, called the medial meniscal tear (MMT) model, results in pathology that highly resembles the pathology that occurs with OA in humans, and is the most common preclinical model used by industry to identify potential therapies that may inhibit cartilage degeneration associated with OA. The second model, the mono-iodoacetate (MIA) model, measures the effects of potential therapies on the pain associated with progressive stages of OA, and is also the most common preclinical model used by industry to identify potential therapies to treat the pain associated with OA. To-date, we have shown cartilage protection in the MMT model with multiple combinations of the prospective APIs, with one formulation generating especially encouraging results. Additionally, in the MIA model, several alternative formulations have demonstrated immediate and early pain reduction in the inflammatory pain phase of the model. The combination of pain reduction and prevention of cartilage degeneration provides optimism that we have a drug candidate to treat OA of the knee (OAK). Of course, we will have to demonstrate these benefits in clinical trials acceptable to regulators and payers, but we are encouraged by these results. Additionally, we want to emphasize that these are results that were never observed with Ampion, nor with the original formulations of AR-300. These results show that we are now in possession of new and unique formulations, separate and distinct from both Ampion and AR-300, that demonstrate their own therapeutic potential. Because of that, we have already taken steps to protect this new intellectual property, worldwide. Based on this progress, we have focused our ongoing efforts toward optimizing two potential formulations to take forward into development. In the third quarter of 2023, we intend to select one of these optimized formulations to move towards clinical development. Given that these formulations are unique, proprietary, and are neither Ampion nor AR-300 (or derivatives thereof), we will now refer to development of these new formulations as OA-20X program. With the data from these additional studies, we will be in position later this year to seek scientific advice meetings with the FDA, UK, and EU regulatory authorities.Secondly, we want to elaborate on our progress in implementing a hybrid, virtual organizational model. From the outset, our intent was (and remains) to retain the organizational capabilities to govern a publicly traded company, comply with related reporting requirements, lead strategy development and program selection, and identify, retain, and manage third-party contractors with specific and proven expertise in the different, related activities required to develop a drug (e.g., drug candidate selection, formulation development, GMP manufacturing, preclinical development, clinical development, regulatory, etc.) on a just-in-time, as needed basis. We believe this model positions us to drive strategic development in the most expeditious and cost-effective way. We communicated, and began implementing, this organizational strategy at the end of 2022 with a planned reduction in force, which continued into the first quarter 2023. In addition, we entered into a sublease agreement effective March 1, 2023, whereby we have subleased the entire Ampio facility in Colorado. As a result of implementing this organizational strategy, Ampio now has five full-time employees, numerous engaged consultants with industry leading expertise in osteoarthritis (OA) drug development (as outlined above) and independent labs and contract manufacturing partners, all collaborating to further the development of the OA-20x program. We expect to remain a Colorado-based company for the foreseeable future and for the time being have retained our current mailing address. We estimate that this strategy will result in annualized cost savings of approximately $4.6 million, allowing us to focus our cash investment on OA-20x development for 2023 in addition to our ongoing governance and reporting obligations as a publicly traded company and other necessary expenses. Again, this update elaborates on just two points from our recently filed Annual Report, and we encourage you to read the full Annual Report in its entirety because it contains important information. We look forward to updating you following conclusion of the third quarter 2023."
YOU

Hot Stocks

06:35 EDT Clear Secure launches new lanes at Bradley International Airport - Clear Secure announced the launch of its identity verification technology at Bradley International Airport, or BDL, bringing frictionless and predictable travel experiences to Connecticut. The company said, "Today's launch represents continued growth in CLEAR's national footprint, where it serves a total of 52 airports and over 15 million members. CLEAR already serves 9 of BDL's top 10 domestic destinations, allowing members traveling through BDL to use CLEAR on both ends of their journey. Members use CLEAR's network of dedicated lanes to verify their identity with their eyes or fingers, replacing the need to take out their wallet and driver's license. After verification, a CLEAR Ambassador escorts members through the dedicated lane and directly to TSA physical security, saving them time waiting in line at the security checkpoint. CLEAR's launch at BDL is expected to create 23 jobs and generate approximately $1.2 million in local economic activity every year."
NXE

Hot Stocks

06:33 EDT NexGen Energy, CRDN establish gravel supply company in Northwest Saskatchewan - NexGen Energy in partnership with the Clearwater River Dene Nation, or CRDN, announced the establishment of a 100% Indigenous owned and operated gravel supply company in Northwest Saskatchewan. Continuing to deliver on its industry-leading Impact Benefit Agreement with the CRDN signed in March 2022, NexGen purchased a $4.1M gravel crusher to provide aggregate material for its Rook I project and to supply the northern communities' aggregate material for road infrastructure requirements. The CRDN member-owned business will lease to own and operate the gravel crusher. The aggregate supply for Rook I has a capital expenditure representing an estimated $36M in value to the new CRDN-owned business in just the first three years of construction of the Project. This new company will immediately create 16 additional jobs for local community members.
GMAB JNJ

Hot Stocks

06:28 EDT Genmab announces Q1 net sales of DARZALEX $2.26B - Genmab (GMAB) announced that worldwide net trade sales of DARZALEX, including sales of the subcutaneous product, as reported by Johnson & Johnson (JNJ) were $2.264B in the first quarter of 2023. Net trade sales were $1.191B in the U.S. and $1.072B in the rest of the world. Genmab receives royalties on the worldwide net sales of DARZALEX, both the intravenous and SC products, under the exclusive worldwide license to Janssen to develop, manufacture and commercialize daratumumab.
PSN

Hot Stocks

06:27 EDT Parsons selected for Chester Bridge replacement project - Parsons's Critical Infrastructure segment has been selected by the Missouri Department of Transportation as a member of the design-build team for the Bi-State Chester Bridge Design-Build project over the Mississippi River between Perryville, MO and Chester, IL to replace the existing aging and outdated truss bridge. Parsons, as a subcontractor to Ames Construction, will serve as lead designer to provide a unique 4-span, 3-tower cable stay bridge design that will minimize risk to navigation traffic on the river.
SIEGY IBM

Hot Stocks

06:05 EDT Siemens Digital Industries Software, IBM expand long-term partnership - Siemens Digital Industries Software (SIEGY) and IBM (IBM) announced they are expanding their long-term partnership by collaborating to develop a combined software solution integrating their respective offerings for systems engineering, service lifecycle management and asset management. The two companies are developing a new systems engineering and asset management combined software solution to support traceability and sustainable product development - linking domains including mechanical, electronics, electrical and software engineering
BFRG

Hot Stocks

06:03 EDT Bullfrog AI signs licensing agreement for oncology asset with university - BullFrog AI announced an exclusive license agreement with Johns Hopkins University for prodrug compositions of mebendazole. The exclusive license was signed on October 13, 2022. The world-wide, royalty-bearing license includes the rights to commercialize N-substituted prodrugs of mebendazole that demonstrate improved solubility and bioavailability relative to the parent compound. The license covers prodrug compositions and use for treating disease as claimed in multiple US and worldwide patent applications.
QH

Hot Stocks

06:03 EDT Quhuo enters global expansion partnership with Karry New Energy Auto - Quhuo has entered into a strategic partnership with Karry New Energy Auto, a business unit under Chery Holding, through Quhuo's new overseas business division Quhuo International to jointly build international operation models for China's new energy vehicles. The latest cooperation marks Quhuo International's strategy to further develop its business lines across various verticals and help selected domestic industry players to expand globally with the company's international expertise and resources. Quhuo International and Karry will work to establish a new business operating model for overseas dealers in the new energy automobile market, based on Karry's years of experience in the domestic market and Quhuo's international channels and smart management platforms. In order to enhance their international brand images, the two companies will promote a selection of new energy products that correspond with market trend.
ERIC

Hot Stocks

05:27 EDT Ericsson says on track to reach target EBITDA range of 15%-18% by 2024 - The company said, "We continue to see a choppy environment during 2023 with poor visibility. In Q2, we expect operators to remain cautious with capex investments and continue to adjust inventories. We expect this dynamic to largely be offset by growth from large roll-out projects which, as noted earlier, will be dilutive to gross margin in the short term. In the Enterprise segment, we remain confident of the long-term growth trajectory, and we expect the slower growth we saw in Q1, caused by the slower global economy, to continue in Q2. For Q2, we expect Group EBITA[2] margin to reach mid-single-digit level. We expect a gradual recovery in the second half of 2023, primarily as we expect the inventory adjustments to be completed and our cost reduction activities to start flowing through the P&L. Long-term, previous experience tells us that when operators are seeing underlying traffic growth, this leads to investments in networks in order to avoid deteriorating quality. Our strategy is paying off and we are excited about our position to capitalize on the full value of 5G. We are driving our transformation to a platform company with a focus on creating a stronger and more profitable Ericsson with a larger addressable market. With the expected recovery by 2024 of the Mobile Networks market, the turnaround of Cloud Software and Services, portfolio adjustments, enhanced R&D productivity, increased IPR revenues and cost reductions, we are on track to reaching the lower end of the long-term EBITA[2] target range of 15-18% by 2024."
MT

Hot Stocks

05:22 EDT ArcelorMittal to form JV with Casa dos Ventos for 554 MW wind power project - ArcelorMittal announced that its Brazilian entity, ArcelorMittal Brazil, will form a joint venture partnership, or JV, with Casa dos Ventos, one of Brazil's largest developers and producers of renewable energy projects, to develop a 554 MW wind power project. ArcelorMittal Brazil will hold a 55% stake in the JV, with Casa dos Ventos holding the remaining 45%. The transaction was approved by the Brazilian antitrust authority, CADE, on April 13 and will be completed within the next 15 days. The R$0.8B project aims to secure and decarbonise a considerable proportion of ArcelorMittal Brazil's future electricity needs. It is estimated it will provide 38 per cent of ArcelorMittal's Brazil's total electricity needs in 2030. The JV will be equity accounted and ArcelorMittal's total equity investment will be R$0.15B.
ESLT

Hot Stocks

05:18 EDT Elbit Systems awarded $102M contract by international customer - Elbit Systems announced that it was awarded a contract worth approximately $102M to supply artillery systems to an international customer. The contract will be performed over a period of eight years. Under the contract Elbit Systems will supply a battalion's worth of ATMOS 155mm/52 caliber truck-mounted howitzers systems. The ATMOS modular artillery system is a combat proven wheeled Howitzer solution, capable of firing all NATO-certified 155mm projectiles that has an effective range of over 40km with standard projectiles and offers extended range with Rocket-Assisted Projectiles, or RAP. The ATMOS is designed for rapid deployment and operation enabling provision of fire support for a broad range of missions.
C VOD

Hot Stocks

05:16 EDT Citi collaborates with Vodafone to reduce emissions through supply chain - Citi (C), in collaboration with Vodafone (VOD), announced the addition of environmental criteria to Vodafone's supply chain finance program, or SCF. Eligible suppliers to Vodafone will now be able to access preferential SCF rates from Citi by disclosing environmental data and demonstrating improvements to their performance. Eligible Vodafone suppliers will be able to access preferential financing rates from Citi based on multiple factors. These include an independent supplier categorization and roadmap framework, which was jointly developed by Vodafone and CDP, a global not-for-profit organization that runs a global environmental disclosure system. It is hoped that this new program will encourage suppliers to reduce their carbon footprint and ultimately contribute towards Vodafone meeting its Scope 3 emissions targets. The launch comes as Citi continues to roll out sustainable Trade and Working Capital solutions, including Sustainability-linked Supply Chain Finance, as part of its commitment to help clients with solutions to achieve their environmental ambitions.
ESLT

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05:12 EDT Elbit Systems awarded $100M follow-on contract by international customer - Elbit Systems announced that it was awarded a follow-on contract worth approximately $100M to convert commercial aircraft into Intelligence and Electronic Warfare, or EW, aircraft for an international customer. The contract will be performed over a period of three years. As part of the contract, Elbit Systems will equip the aircraft with advanced Intelligence Mission Suite and EW capabilities. This solution will provide a comprehensive operational picture of the arena generated by SIGINT and Electro-Optics VISINT sensors and systems as well as the capability to activate Electronic Counter Measures against a range of threats. The aircraft will also be equipped with Immune Satellite Navigation Systems, or ISNS, and an advanced self-protection solution.
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05:09 EDT Ginkgo Bioworks, Cambrium complete protein production collaboration - Cambrium and Ginkgo Bioworks announced the successful completion of their collaboration. Through the partnership, Cambrium and Ginkgo combined their capabilities to enable the rapid and cost-effective design of industrially relevant microbes for protein production.