Stockwinners Market Radar for October 06, 2022 - Earnings, Upgrades downgrades, option trades, Best Stock Advisory Service

20:35 EDT Alnylam announces FDA approval of Oxlumo in primary hyperoxaluria - Alnylam "announced that the FDA approved a label expansion for OXLUMO, lumasiran, an RNAi therapeutic administered via subcutaneous injection, now indicated for the treatment of primary hyperoxaluria type 1 to lower urinary oxalate and plasma oxalate levels in pediatric and adult patients. The approval is based on positive efficacy and safety results of the ILLUMINATE-C Phase 3 study of OXLUMO in patients with severe renal impairment, including those on hemodialysis. The FDA approval is based on positive six-month results from the ILLUMINATE-C Phase 3 study, in which OXLUMO treatment resulted in substantial reductions in POx and demonstrated an encouraging safety and tolerability profile in patients with compromised renal function, including those with kidney failure and undergoing treatment by hemodialysis. Elevated POx is directly related to the pathophysiology of oxalosis and results in systemic deposition of oxalate in extra-renal tissues, potentially leading to bone fractures, cardiomyopathy, impaired erythropoiesis, vision loss, skin ulcers and other serious manifestations."

20:06 EDT Cathie Wood's ARK Investment bought 94K shares of Rocket Lab today

19:54 EDT Merck, Ridgeback Biotherapeutics provide update on studies of Lagevrio - Merck and Ridgeback Biotherapeutics "issued the following announcement regarding data from two real-world evidence studies evaluating LAGEVRIO, or molnupiravir, an investigational oral antiviral COVID-19 medicine. The first study, PANORAMIC, was conducted by the University of Oxford in the UK in highly-vaccinated adults mostly less than age 65 during the period when the circulating SARS-CoV-2 variant was predominantly Omicron. The second study, Clalit, was conducted by investigators in Israel in mostly older adults with underlying chronic health conditions that make them vulnerable to severe COVID-19 disease, also when Omicron was the most dominant strain. The PANORAMIC pre-print was published today and the Clalit pre-print was published last week. Additionally, Merck is reporting results from a recent carcinogenicity study in transgenic mice, which demonstrated that LAGEVRIO was not carcinogenic at any dose tested. The PANORAMIC study, a UK-based clinical trial sponsored by the University of Oxford, included 25,783 participants who were randomized to open label treatment with LAGEVRIO plus usual care or usual care alone; mean age of participants was 56.6 years. Primary outcome data were available in 25,000 participants. Nearly all participants were vaccinated, with approximately 95% receiving three or more doses of a SARS-CoV-2 vaccine. In the preliminary analysis, the primary endpoint of reduction of hospitalizations and deaths within 28 days of randomization, compared to usual care, was not met; 0.8% of patients in both the LAGEVRIO group and the usual care group were hospitalized or died in the first 28 days. On secondary objectives, LAGEVRIO was associated with improvement on a range of measures compared to usual care. The observed median time to first self-reported recovery was 6 days shorter in the LAGEVRIO group; the median time to first recovery was 9 days on LAGEVRIO vs. 15 days on usual care (range 7 to not reached). Following adjustment for age and baseline comorbidity, there was a substantial estimated improvement of 4 days in time-to-first recovery in the LAGEVRIO group vs. usual care group. The finding on time-to-first recovery was consistent for LAGEVRIO across key subgroups. Secondary objectives were not adjusted for multiplicity. Results from the Clalit study: In this observational, retrospective cohort study, LAGEVRIO was associated with a lower rate of hospitalizations and mortality due to COVID-19 in patients 65 years and above, but not in younger adults. In patients 65 years of age and above, hospitalizations related to COVID-19, the primary endpoint, occurred in 18 LAGEVRIO-treated patients and in 513 untreated patients; adjusted hazard ratio for hospitalization was 0.55. The secondary endpoint of death due to COVID-19 in this same age group occurred in 4 of 845 LAGEVRIO-treated and 137 of 12,724 untreated patients; adjusted HR=0.26. In patients 40 to 64 years of age, hospitalizations related to COVID-19, the primary endpoint, occurred in 8 treated patients and 97 untreated patients , and adjusted HR for hospitalization was 1.80. The secondary endpoint of death due to COVID-19 in this same age group occurred in 4 of 224 LAGEVRIO-treated and 7 of 6,075 untreated patients; adjusted HR=12.82. All four deaths in the LAGEVRIO-treated group occurred in patients 60-64 years of age."

19:35 EDT Biohaven Pharmaceutical CEO buys $5.0M in common stock - In a regulatory filing, Biohaven Pharmaceutical disclosed that its CEO Vlad Coric bought 486K shares of common stock on October 5th in a total transaction size of $5.0M.

19:02 EDT BioMarin redesigns organization, will lay off about 4% of its workforce - BioMarin Pharmaceutical announced its decision to redesign the organization to better focus investments that advance its R&D pipeline, maximize recent commercial launch success, prepare for a potential launch of ROCTAVIAN in the U.S., and drive core infrastructure optimization. This redesign simplifies the organization, creates efficiencies, reduces the average management layers across the organization and prioritizes and heightens the capabilities required to achieve critical business needs of the future. As a result, this decision will involve a reduction in force of approximately 120 employees, or roughly four percent of the global workforce. "We want to recognize everyone impacted by this initiative for their contributions on behalf of the patients we serve. Change is necessary to fulfill our commitment to operating the business in the best interest of our patients, shareholders, and other stakeholders. This requires that our organization is the right size, has the right structure, and has the right focus to operate with maximum effectiveness and efficiency," said Jean-Jacques Bienaime, Chairman and CEO of BioMarin. "This change allows us to continue building upon our core strength in genetic discovery to have a transformative impact on the lives of even more patients." While the focus of the effort was reshaping the organization for operational effectiveness and efficiency, the reduction in force will result in financial savings of approximately $50 million annually beginning in 2023. Management expects to reinvest a significant portion of the savings in BioMarin's clinical development portfolio, early-stage pipeline, and Roctavian and Voxzogo launches, while the remainder will contribute to the Company's goal of increasing profitability and expanding operating margins. Impacted employees have been notified as of this week, and they have begun the transition process that will be fully supported by the Company. Most of the reduction will come from BioMarin's U.S. operations and the reductions are expected to be substantially completed by December 31, 2022. As a result of the reduction in force, the Company will incur total estimated pre-tax charges of approximately $20 - $25 million spread across the third and fourth quarters of 2022, representing one-time cash expenditures for severance and employee termination benefits.

17:58 EDT Teck Resources reports Q3 steelmaking coal sales and pricing - Teck Resources provided unaudited Q3 steelmaking coal sales of 5.6 million tons, within revised guidance of 5.5-5.9 million tons. Q3 realized steelmaking coal price averaged $304 per ton. The company expects to report negative provisional pricing adjustments of $191M in Q3 due to the decline in steelmaking coal prices during the quarter.

17:36 EDT DraftKings jumps 8% to $17.39 after report of a partnership with ESPN

17:31 EDT Bachoco receives voluntary tender offer for 27% of outstanding capital stock - Bachoco announced that a vehicle in which current shareholders of the Robinson Bours family participate communicated to Bachoco's Board the commencement of a voluntary tender offer for up to all of the outstanding shares of Bachoco, including shares represented by American Depositary Receipts or ADRs, which are not owned directly or indirectly by the offeror or its affiliates, representing approximately 27% of the outstanding capital stock of Bachoco, at a price of 81. 66 Mexican pesos per share, payable in cash and in Mexican currency. The offer is being conducted concurrently in Mexico and the U.S. The tender offer comprises a Mexican offer open to all holders of Bachoco shares, and a U.S. offer open to all U.S. holders. The offer is expected to expire on November 4, unless extended on the terms described in the offer documents disclosed by the offeror.

17:27 EDT MSG Sports announces $7.00 special dividend - Madison Square Garden Sports "announced its Board of Directors has declared a special, one-time cash dividend of approximately $175M, or $7.00 per share. The special dividend is payable on October 31, 2022 to MSG Sports shareholders of record on October 17, 2022."

17:20 EDT Bachoco receives voluntary tender offer for all outstanding shares - Bachoco announced that a vehicle in which current shareholders of the Robinson Bours family participate communicated to Bachoco's Board the commencement of a voluntary tender offer for up to all of the outstanding shares of Bachoco, including shares represented by American Depositary Receipts or ADRs, which are not owned directly or indirectly by the offeror or its affiliates, representing approximately 27% of the outstanding capital stock of Bachoco, at a price of 81. 66 Mexican pesos per share, payable in cash and in Mexican currency. The offer is being conducted concurrently in Mexico and the U.S. The tender offer comprises a Mexican offer open to all holders of Bachoco shares, and a U.S. offer open to all U.S. holders. The offer is expected to expire on November 4, unless extended on the terms described in the offer documents disclosed by the offeror.

17:18 EDT Lantheus to replace Targa Resources in S&P 400 at open on 10/12

17:17 EDT Targa Resources to replace Nielsen in S&P 500 at open on 10/12 - Elliot Management Corp is acquiring Nielsen Holdings in a transaction expected to close October 11.

17:01 EDT Poseidon Acquisition continues talks to acquire Atlas Corp. shares - Poseidon Acquisition Corp., on behalf of a consortium composed of David L. Sokol, Chairman of the Board of Directors of Atlas Corp., certain affiliates of Fairfax Financial Holdings Limited, the Washington Family, and Ocean Network Express Pte. Ltd., a global container, transportation and shipping company, announced it believes it has made meaningful progress in its discussions with the Special Committee of the Board of Directors of Atlas to acquire all of the outstanding common shares of Atlas that the members of the Consortium do not already own or control for $15.50 per share in cash, plus payment of all ordinary course third quarter and fourth quarter 2022 dividends regardless of the timing of any closing. There is no binding agreement with respect to the Proposed Transaction, and negotiations remain subject to significant contingencies, including completion of due diligence by the Consortium, the negotiation and execution of a mutually acceptable definitive agreement, and confirmation and documentation of fully committed financing. In addition, the closing of the Proposed Transaction, if a definitive agreement is reached, would be contingent upon the approval of holders of a majority of the Atlas common shares not owned by Consortium members and the satisfaction of additional mutually acceptable closing conditions to be contained in a definitive agreement. The Consortium does not expect to make any further announcements or updates unless and until a definitive agreement is executed or discussions with the Special Committee are terminated.

16:33 EDT Karuna Therapeutics to present data from Phase 3 trial of KarXT - Karuna Therapeutics "announced that data from the Phase 3 EMERGENT-2 trial of KarXT in schizophrenia will be shared at the 35th European College of Neuropsychopharmacology Congress, to be held October 15-18, 2022, in Vienna, Austria. A poster presentation and symposium will include previously reported efficacy and safety data, as well as new additional safety data from the trial."

16:31 EDT Agrify issues statement refuting customer lawsuit - Agrify issued the following statement relating to the default of its customer Bud & Mary's Cultivation, Inc. under a construction loan facility extended by Agrify to Bud & Mary's associated with an Agrify Total Turn-Key Solution project and the lawsuit brought by Bud & Mary's in response to the default notice: "Bud & Mary's was notified by Agrify that it was in default of its credit facility and subsequently responded with a meritless lawsuit in an obvious attempt to avoid repayment of the credit facility. Bud & Mary's lawsuit is entirely without merit. Agrify has worked closely and transparently with Bud & Mary's team throughout the entire design and build process. Agrify fully complied with its contractual obligations under the Agrify TTK Solution agreements. Agrify is taking all necessary steps to pursue repayment from Bud & Mary's and will take all actions necessary to protect its shareholders' interests."

16:30 EDT Signature Bank announces further expansion into Nevada - Signature Bank announced further expansion of its West Coast presence with the appointment of veteran banking professionals and the opening of a new private client banking office in Reno, Nevada. Signature Bank is now home to 35 teams on the West Coast, led by 56 Group Directors from its eight offices. Also, the Bank's West Coast footprint includes representation from its subsidiary Signature Financial as well as from all its national banking practices, including the Fund Banking Division, the Venture Banking Group, the Specialized Mortgage Banking Solutions team and the SBA Lending team. Signature Bank is also in the process of elevating operations and to this end, is establishing an operational center in City of Industry, California, to further support its growing businesses in the area and across the country. To lead its banking efforts in Nevada, Signature Bank named Christopher Uboldi to the post of Managing Group Director and Senior Vice President. In this capacity, Uboldi will direct and manage six private client teams and 25 banking professionals throughout Nevada and the greater Sacramento, Calif. area. Uboldi will be based out of the Bank's new private client banking office located at 100 West Liberty Street, Suite 190, Reno, Nevada, 89501.

16:24 EDT Gladstone Land provides update following price volatility of common stock - Gladstone Land announced that, in light of the recent price volatility of its common stock, it is providing the following business update. The company said, "With inflation continuing to hover near the highest rates seen in over four decades, farmland continues to act as a strong hedge against inflation. According to the U.S. Bureau of Labor Statistics, CPI grew at an annual rate of 8.3% through August 2022. However, food prices have continued to outpace the rate of inflation, with the overall food segment increasing by 11.4% over that same period, and the food at home segment (which encompasses the majority of the crops grown on Gladstone Land's farms) growing by 13.5%. In addition, according to the NCREIF Farmland Index, which, as of June 30, 2022, consisted of over $14.6 billion of farms across the U.S., the total return on U.S. farmland (including appreciation and income) was 9.7% for the 12 months ended June 30, 2022 (results released quarterly). Gladstone Land's farms continue to be 100% leased, and the Company has collected approximately 97.7% of year-to-date base cash rents owed through September 30, 2022. The remaining portion of approximately $1.2 million is currently expected to be collected in full by the end of the year. Since June 30, 2022, the Company has renewed or extended six leases on certain of its farms located in Arizona, California, and Florida. In aggregate, these renewals are expected to result in an increase in annual net operating income of approximately $281,000, or 9.8%, from that of the prior leases. The Company does not have any more agricultural leases expiring in 2022 and only has one agricultural lease expiring in the first half of 2023, which makes up less than 0.5% of its total annual lease revenues. Management currently expects the renewal of this lease to be flat-to-slightly-higher relative to the current lease. Gladstone Land currently has approximately $642.7 million of total debt outstanding (excluding mandatorily redeemable term preferred stock). Over 99.8% of these borrowings are at fixed rates, and on a weighted-average basis, the interest rate on these borrowings is fixed at just 3.26% for the next 5.1 years. As such, management believes its current debt situation is well-protected against continued interest rate increases, as is currently expected. The Company currently has available liquidity of approximately $172.3 million, consisting of approximately $45.0 million in cash on hand and approximately $127.3 million of availability under our credit facility with MetLife and other undrawn notes or bonds. In addition, Gladstone Land currently has certain properties valued at a total of approximately $104.8 million that are unencumbered and eligible to be pledged as collateral. Representatives from Gladstone Land have spoken with its tenant-partners across the State of Florida. While the Company is still assessing the overall impact of the hurricane, early reports indicate only minor damage to a couple of farm-related buildings and irrigation systems, all of which is covered by insurance. Some farmers also reported delayed plantings for certain crops and crop loss in some fields due to the amount of surface water produced by Hurricane Ian; however, the Company does not currently anticipate these delays to cause any interruption in rental payments. The Company notes that its two citrus groves in St. Lucie County (the only permanent crop farms it owns in the state) made it through the storm without any notable damage to the trees. Gladstone Land is grateful to have come out relatively unscathed given the strength of this historic storm and continues to keep those in mind who were negatively impacted as a result of the hurricane. The drought in the West continues to persist, and many farmers are in need of more rain and a strong snowpack this winter to maintain optimal yields on their farms, including certain of our tenants. But at this time, none of the Company's farms are impaired as a result of the drought. The Company continues to see increasing demand for farmland by growers in certain markets, resulting in upward pressure on rental rates. In addition, values of farmland with poor water resources are generally trending down, while farmland with good water access is showing a sharp increase in value, hence Gladstone Land's continued efforts to increase the amount of water availability on its farms. The Company continues to work on projects to enhance the water security of its western portfolio, including, but not limited to, additional water purchases, installation of new pipelines, and improvements to existing irrigation systems. Critically dry cycles, like the one the West is currently experiencing, is why the Company purchased 45,000 acre-feet (equal to approximately 14.7 billion gallons) of banked water last year (none of which has been used to date) and continues to look at other opportunities to acquire additional water."

16:22 EDT Levi Strauss falls 3% to $15.40 after Q3 earnings, FY22 guidance cut

16:17 EDT Allogene Therapeutics initiates ALLO-501A trial - Allogene Therapeutics announced the initiation of the potentially pivotal Phase 2 clinical trial of ALLO-501A, or ALPHA2 trial, in patients with relapsed/refractory large B-cell lymphoma, or LBCL. The company is also in the process of initiating the EXPAND trial, which is intended to demonstrate the contribution of ALLO-647 to the standard fludarabine/cyclophosphamide lymphodepletion regimen. Assuming favorable outcomes and subject to discussions with the FDA, the company expects these studies to support the regulatory approval of both ALLO-501A and ALLO-647.

16:13 EDT LightPath expects Q1 revenue impact of $400,000-$700,000 from Hurricane Ian - LightPath provided an update regarding the impact of Hurricane Ian. The company's largest manufacturing facility and a significant employee base are located in and around the Orlando, Florida area. "Due to the magnitude and path of Hurricane Ian, our Orlando facilities were closed for nearly three days last week, constituting the final three days of the fiscal quarter. The decision to close these facilities was to ensure our employees and their families were safe, and was done in accordance to the local government's guidelines," said Sam Rubin, CEO of LightPath Technologies. "The facility closure resulted in a delay of shipments which impacted revenue for the final week of the fiscal 2023 first quarter. An initial assessment is that fiscal first quarter revenues could be negatively impacted by $400,000 to $700,000 due to delayed shipping of orders."

16:11 EDT Mersana Therapeutics completes patient enrollment in UPLIFT trial - Mersana Therapeutics announced the completion of patient enrollment in UPLIFT, the company's single-arm registrational trial of UpRi in platinum-resistant ovarian cancer. UpRi is Mersana's first-in-class NaPi2b-targeting ADC with a novel scaffold-linker-payload that enables a high drug-to-antibody ratio and controlled bystander effect.

16:09 EDT Lyell Immunopharma announces FDA clearance for LYL845 IND application - Lyell Immunopharma announced that the FDA has cleared its Investigational New Drug, or IND, application to initiate a Phase 1 clinical trial for LYL845. LYL845 is an investigational tumor infiltrating lymphocyte therapy enhanced with Lyell's Epi-R technology for patients with relapsed and/or refractory metastatic or locally advanced melanoma and other select solid tumors. In preclinical studies, Epi-R creates polyclonal populations of T cells that demonstrate properties of durable stemness and anti-tumor functionality. Durable stemness is the quality that enables T cells to self-renew, proliferate, persist and generate differentiated effector cell progeny.

16:06 EDT TransAct selected to provide printing solutions for Sky River Casino - TransAct Technologies Incorporated (TACT) announced that it has been selected by Sky River Casino located in Elk Grove, California to provide TransAct's industry-leading Epic Edge TITO printer in all slot machines within the 100,000 square foot gaming floor. Sky River Casino was developed and built for the Wilton Rancheria Tribe by Boyd Gaming (BYD) who will operate their 2,000 slot machines and 80 table games. "TransAct is ecstatic to support Sky River Casino's commitment to giving guests a top-notch gaming experience, and the Epic Edge is the perfect fit to meet their goals," said Bart Shuldman, CEO of TransAct Technologies. "Sky River Casino is focused on providing the best customer experience and we selected the Epic Edge for its superior performance and features," said Chris Gibase, Senior Vice President of Boyd Gaming.

15:43 EDT Caesars submits mobile sports betting license application in Maryland - Horseshoe Casino Baltimore filed an application for a mobile sports betting license that delivers on a promise to include a significant ownership interest by local women and minority partners. Under the terms of the application - which was submitted under the name CZR Maryland Mobile Opportunity, and is pending regulatory review and approval - women and minority partners will hold a 40% ownership interest in the mobile gaming license that would be utilized by Caesars Sportsbook. Partners in CZR Maryland Mobile Opportunity's mobile gaming license application include: PRT 2-Digital, a Baltimore-based partnership group including local businesspeople Eddie Brown, Cecil Flamer, Maria Beckett and James Scott, Jr.; Letha Christian, a local information technology professional and Caesars Entertainment, majority owner and operator of Horseshoe Baltimore.

15:18 EDT President Biden says taking steps on marijuana reform - The White House issued a statement from President Biden that reads in part: "As I often said during my campaign for President, no one should be in jail just for using or possessing marijuana. Sending people to prison for possessing marijuana has upended too many lives and incarcerated people for conduct that many states no longer prohibit... Today, I am announcing three steps that I am taking to end this failed approach. First, I am announcing a pardon of all prior Federal offenses of simple possession of marijuana. I have directed the Attorney General to develop an administrative process for the issuance of certificates of pardon to eligible individuals... Second, I am urging all Governors to do the same with regard to state offenses. Just as no one should be in a Federal prison solely due to the possession of marijuana, no one should be in a local jail or state prison for that reason, either. Third, I am asking the Secretary of Health and Human Services and the Attorney General to initiate the administrative process to review expeditiously how marijuana is scheduled under federal law... Finally, even as federal and state regulation of marijuana changes, important limitations on trafficking, marketing, and under-age sales should stay in place. Too many lives have been upended because of our failed approach to marijuana. It's time that we right these wrongs." Publicly traded companies in the cannabis space include Aurora Cannabis (ACB), CV Sciences (CVSI), CannTrust Holdings (CNTTF), Canopy Growth (CGC), Cronos Group (CRON), General Cannabis (CANN), Goodness Growth (GDNSF), Green Thumb Industries (GTBIF), India Globalization Capital (IGC), Tilray (TLRY), Trulieve Cannabis (TCNNF) and Zynerba (ZYNE). Reference Link

15:15 EDT AMC announces pact with Netflix to screen 'Glass Onion' - AMC Theatres (AMC) announced that the company has reached its "first-ever agreement" with Netflix (NFLX) to play a Netflix movie theatrically. From November 23-29, AMC moviegoers can view "Glass Onion: A Knives Out Mystery" at more than 200 locations throughout the United States. It will also play at select Odeon Cinema Group's locations in the UK, Ireland, Italy, Germany, and Spain. "The agreement with Netflix to play GLASS ONION: A KNIVES OUT MYSTERY adds another major theatrical title to an already exciting slate of movies that will appeal to broad audiences during the Thanksgiving weekend. Tickets go on sale Monday, October 10," AMC stated. Adam Aron, AMC Chairman and CEO, commented: "This announcement of our first-ever agreement with Netflix is significant for AMC and for movie lovers around the world. As we have often said, we believe that both theatrical exhibitors and streamers can continue to co-exist successfully. Beyond that, though, it has been our desire that we find a way to crack the code and synergistically work together. By doing so, theatres will make more money by having more titles to show, and thanks to the larger cultural resonance those movies can gain from a theatrical release, they will wind up playing to a wider audience when they also are viewed on streaming platforms. Accordingly, we also have long said that we would welcome Netflix movies in our theatres with the proper agreements in place."

15:01 EDT General Dynamics Electric Boat announces $533M submarine support award - General Dynamics Electric Boat, a business unit of General Dynamics, announced it was awarded a U.S. Navy contract modification for lead-yard support, development studies and design efforts related to Virginia-class attack submarines. The contract modification has a value of $532.9M. Work will be performed in Groton, Connecticut, and Newport News, Virginia, and is expected to be completed by October 2023.

14:45 EDT Duke Energy requests rate review by North Carolina Utilities Commission - Duke Energy Progress asked North Carolina regulators to review its rates as the company said it "continues to strengthen the electricity grid, reducing power outages for customers and facilitating a clean, secure energy future in a manner that supports economic development across the state." "Our customers count on us to deliver affordable, reliable and increasingly clean energy every day," said Stephen De May, Duke Energy's North Carolina state president. "We're sensitive to the financial pressures our customers face, and we remain committed to keeping rates as low as possible."

14:10 EDT LME issues discussion paper on Russian metal - The London Metal Exchange, or LME, has issued a discussion paper on Russian metal, stating in a summary: "Since Russia invaded Ukraine on 24 February 2022, specific sectoral sanctions and related measures against Russia have been introduced; however, there has been no comprehensive government-led action to prevent the widespread use of Russian metal. In parallel, the LME has been closely monitoring the usage and throughflow of Russian metal on the LME, to ensure that LME warehouses do not see a significant inflow of unwanted Russian stocks, posing a risk of creating a disorderly or unfair market. Through 2022, the LME's understanding is that consumers have broadly been willing to take deliveries of Russian metal, which is supported by data as to the flow of Russian stocks both into and out of LME warehouses. However, as the current negotiation period for 2023 supply agreements progresses, the LME understands that an increasing number of consumers may be expressing an unwillingness to accept Russian metal in 2023. As a result, and in light of the potentially changing market landscape, the LME now considers it appropriate to gather further data and views. This paper considers the role of the LME in this scenario, provides background and data on the subject, and asks for market feedback on possible routes forward." Aluminum stocks that have previously moved in reaction to reports that the London Metal Exchange was launching a discussion of a potential ban on new supplies of Russian metal include Alcoa (AA), Century Aluminum (CENX), Kaiser Aluminum (KALU), Constellium (CSTM) and Arconic (ARNC). Reference Link

13:57 EDT Twitter down 2% after Bloomberg says Musk talks suck on debt contingency - Twitter shares are down 2% to $50.09 in afternoon trading.

13:38 EDT Faraday Future directors resign, citing death threats - In a regulatory filing, Faraday Future Intelligent Electric disclosed that on October 3, each of Susan Swenson, the Executive Chairperson of the company, Jordan Vogel, the company's Lead Independent Director, and Scott Vogel provided notice of their resignations as members of the company's board of directors and from all other positions that they hold at the company and its subsidiaries. "Each of Ms. Swenson and Mr. Scott Vogel resigned effective immediately. Mr. Jordan Vogel's resignation was effective on October 5, 2022 upon his receipt of a supplemental release from the company and its subsidiaries, FF Global Partners LLC, the executive committee members of FFGP and their controlled affiliates, and FFGP's controlled affiliates as contemplated by the Mutual Release, dated as of September 23, 2022, by and among the Non-Director Parties and the directors of the company and their controlled affiliates. Effective as of Ms. Swenson's resignation as Executive Chairperson on October 3, 2022, Adam (Xin) He was appointed to serve as Interim Chairman of the Board. The company expects that the Board seated after the 2022 annual meeting of stockholders will select a permanent Chairperson of the Board. Following the completion of the Special Committee investigation, the company and certain of its directors and officers have received numerous e-mail communications from a group of self-described 'employee whistleblowers' and from various individuals and entities who represented themselves as current investors of the Company. These communications have included various allegations and requests for certain organizational and governance changes. The company engaged an independent law firm to conduct a thorough independent external investigation with respect to these allegations. The independent investigation found that all such allegations have been without merit. In September 2022, certain members of the Board received threats of physical violence and death threats, which the company has referred to appropriate law enforcement authorities, including state and local police, the Federal Bureau of Investigation, the SEC, the U.S. Department of Justice and relevant international authorities. Each of Ms. Swenson, Messrs. Jordan Vogel and Scott Vogel cited such threats and their fear that their continued association with the company might heighten the risk to themselves and their respective families as the reasons for their resignations. Following the resignation of Ms. Swenson, all company management now report directly or indirectly to Dr. Carsten Breitfeld, the Global Chief Executive Officer of the company, for a 21-day period beginning on October 4, 2022 while the Board continues to evaluate the appropriate management reporting lines," the filing stated.

13:29 EDT Select Medical plans to open third patient rehabilitation hospital in Central PA - Select Medical today announced it plans to open a third inpatient rehabilitation hospital in Central Pennsylvania to serve the expanding needs of the West Shore region. The new freestanding hospital, in partnership with UPMC, will feature 35 private rooms and rehabilitation equipment to treat patients recovering from stroke, spinal cord injury, brain injury, amputation, neurological disorders and orthopedic conditions. The company currently operates two other inpatient rehabilitation hospitals on Central Pennsylvania's East Shore through joint venture partnerships. Targeting a 2023 opening, Select Medical will renovate an existing building located on UPMC's West Shore Campus on Technology Parkway in Mechanicsburg to expedite time to market.

12:51 EDT S&P raises Tesla credit rating to investment grade with stable outlook - S&P Global Ratings raised its ratings on Tesla, including our issuer credit rating and issue-level ratings, to "BBB" from "BB+." Tesla's reported production and deliveries for the nine months ended September 30 were higher than expectations and the ramp-up in its global capacity appears on track to "meet the strong demand for its products into 2023," S&P said in a statement. The firm now views Tesla's credit profile more favorably saying the company continues to demonstrate market leadership in electric vehicles, with "solid manufacturing efficiency that supports strong EBITDA margins and sustained positive free operating cash flow." S&P adds that its "stable outlook" reflects expectations that Tesla will maintain low debt levels.

12:05 EDT Inpixon board approves share consolidation for Nasdaq compliance - Inpixon announced that the Company's Board of Directors has approved a consolidation of the Company's common stock whereby every seventy-five shares of its outstanding common stock will automatically be combined into one share of common stock. The reverse stock split is being implemented for the purpose of complying with applicable Nasdaq Listing Rules, including the closing bid price requirement and such other minimum bid price rules to the extent they may be applicable, in connection with future strategic transactions. The reverse stock split will be effective as of the commencement of trading on Friday, October 7, 2022. At such time, the common stock will also commence trading with a new CUSIP number, 45790J867. In accordance with the reverse stock split, each stockholder's percentage ownership interest in Inpixon will remain unchanged. Any fractional shares resulting from the reverse stock split will be rounded up to the nearest whole share of common stock. Concurrent with the reverse stock split, the authorized shares will also be proportionately reduced consistent with the reverse split ratio.

12:02 EDT GM Defense to provide battery electric technology to DIU - GM Defense, a subsidiary of General Motors, was selected by the Defense Innovation Unit to develop a battery pack prototype for testing and analysis on Department of Defense platforms. GM Defense will leverage GM's most advanced battery technology, the Ultium Platform, as it works to meet DIU's requirement for a scalable design that can be used for tactical military vehicles, the company said in a statement. "This award is a critical enabler for non-traditional defense businesses like GM Defense to deliver commercial technologies that support our customers' transition to a more electric, autonomous and connected future," said Steve duMont, president of GM Defense.

12:00 EDT Integer falls -8.6% - Integer is down -8.6%, or -$5.69 to $60.60.

12:00 EDT Natuzzi falls -10.2% - Natuzzi is down -10.2%, or -66c to $5.80.

12:00 EDT BrightSphere rises 9.2% - BrightSphere is up 9.2%, or $1.46 to $17.32.

11:33 EDT Daktronics selected to install displays at Crypto.com Arena - Daktronics were selected to manufacture and install all new end wall video displays and more than 3,000 linear feet of ribbon displays at Crypto.com Arena in Los Angeles, California. The project was installed over the summer months during the arena's first phase of renovations and will be used to entertain fans, show statistics, run promotions and sponsorship inventory during Los Angeles Lakers, LA Kings, Los Angeles Clippers and Los Angeles Sparks games starting this season.

11:04 EDT Google unveils new Pixel portfolio of products - In a blog post by Google's Rick Osterloh, Senior Vice President, Devices & Services, the executive states: "Today, we're introducing a true portfolio of Pixel products for the first time: the new Pixel 7 and Pixel 7 Pro, and the very first Google Pixel Watch. Every Pixel device is designed to deliver a level of personal intelligence that turns day to day problems into truly delightful experiences. All of this is brought to life thanks to our combination of foundational technologies, artificial intelligence, Android and Google Tensor. This is what we have been building up to for a while: delivering a lineup of beautifully designed Pixel phones, watches and earbuds that work together to understand your needs and deliver the helpfulness you expect from Google... As the Pixel portfolio expands the phone is at the center of it all. The new Pixel 7 and Pixel 7 Pro take all the helpfulness and personal intelligence people love about Pixel, and make them even better... Our new Google Pixel Watch, is the first smartwatch to provide the best of Google and Fitbit, and it's the perfect companion to our Pixel phones... Earlier this year at I/O, we previewed plans to build an Android tablet powered by our custom Tensor G2 processor. And today, we shared more about our vision for making the Pixel Tablet the most helpful tablet whether you're at home or on the go... From their design to the high-tech features, these latest products embody the best of Google. You can learn more about them and pre-order the new Pixel phones and the new Google Pixel Watch in the Google Store, or from our partners around the world. In fact, we're expanding the availability of Pixel phones to more places, including Denmark, Netherlands, Norway, and Sweden for the first time." Reference Link

11:00 EDT Sylvamo Corp trading resumes

10:51 EDT Norwegian Cruise Line sees return to historical load factors in 2023

10:46 EDT Sylvamo completes sale of Russian operations - Sylvamo is announcing it reached an agreement and completed the sale of its Russian operations to Pulp Invest Limited Liability Company for $420M. After foreign currency exchange rates and transaction fees, Sylvamo received approximately $390M in cash proceeds. Sylvamo announced its decision to sell all of its Russian operations in May. Pulp Invest, a management buyout vehicle, funded the purchase price through bank financing. A Form 8-K, including updated pro forma financial statements, will be made available, the company noted. "We made a principle-based decision to exit Russia and believe Pulp Invest is the best option for our Russian colleagues and assets. We intend to use $325 million of the proceeds to repay debt," said Jean-Michel Ribieras, chairman and CEO.

10:31 EDT Enviva Partners appoints Mark Coscio as CDO - Enviva announced that it has appointed Mark Coscio as Executive Vice President and Chief Development Officer. In his new role, Coscio will be responsible for leading Enviva's corporate development and construction functions. Most recently, Mr. Coscio served as Senior Vice President, North, Central & South America at McDermott International.

10:12 EDT Nauticus Robotics Inc trading resumes

10:07 EDT Nauticus Robotics Inc trading halted, volatility trading pause

10:03 EDT Trimble changes headquarters to Westminster, Colorado - Trimble announced that the company has changed its headquarters from Sunnyvale, California to Westminster, Colorado. Westminster is Trimble's largest employment center in the U.S. and serves as a central business hub for several of Trimble's core market segments including agriculture, construction and geospatial. In addition, Trimble's CEO, CFO, a number of its senior business leaders, and more than 1,000 employees are located in Westminster. Sunnyvale will continue to be a strategic hub for Trimble and has been designated as the Silicon Valley Center for Innovation and Operations.The headquarters change will have no material impact on Trimble management, employees or customers.

10:01 EDT Hippo appoints Kelly Wolf as CHRO - Hippo announced that Kelly Wolf has joined the company as Chief Human Resources Officer. Wolf will lead Hippo's human resources team and is responsible for critical people-centered functions including employee relations, talent acquisition and management, and leadership development. Kelly joins Hippo from online retailer Zulily where she was VP of People, overseeing human resources, talent acquisition, DE&I and more.

10:00 EDT Senti Biosciences Inc trading resumes

10:00 EDT Global Medical REIT falls -5.5% - Global Medical REIT is down -5.5%, or -47c to $8.10.

10:00 EDT BrightSphere rises 7.5% - BrightSphere is up 7.5%, or $1.19 to $17.05.

10:00 EDT Compass rises 19.3% - Compass is up 19.3%, or 49c to $3.04.

09:55 EDT Senti Biosciences Inc trading halted, volatility trading pause

09:47 EDT Shell falls -5.2% - Shell is down -5.2%, or -$2.79 to $51.23.

09:47 EDT J.Jill falls -9.4% - J.Jill is down -9.4%, or -$1.60 to $15.45.

09:47 EDT China Eastern Airlines rises 5.8% - China Eastern Airlines is up 5.8%, or $1.02 to $18.64.

09:46 EDT WPP acquires Passport Brand Design, terms not disclosed - WPP announces the acquisition of Passport Brand Design, a brand design agency based in Southern California. The company said, "Founded in 2004 by Natalie Taormina and Jeremy Creighton, Passport brings extensive brand identity, design expertise and insight into WPP and works across a broad range of consumer categories and global markets, spanning Australia and Asia to North America." The agency will join VMLY&R's global network, creating exciting new partnership opportunities for existing talent and clients and expanding VMLY&R's presence in the West Coast region.

09:39 EDT Chardan NexTech Acquisition 2 Corp trading resumes

09:34 EDT State Street, FundGuard enter partnership for accounting solutions - State Street announced that FundGuard has been selected to serve as a strategic accounting solution for State Street Alpha. FundGuard is a highly scalable cloud-native investment accounting, fund accounting, and contingency NAV solution. The FundGuard accounting solution will be integrated for straight through processing from portfolio management and trading in the Charles River Investment Management Solution through to custody and administration. A co-engineered technology-only solution that spans front office and accounting capabilities will also be natively available within the platform for Charles River clients.

09:33 EDT 22nd Century announces availability of VLN cigarettes across Colorado - 22nd Century announces VLN cigarettes are now available at all Smoker Friendly locations in the Colorado via a partnership with Creager Mercantile and will be available in Colorado Circle K stores by next week. VLN is also rolling out to retail locations throughout the state, through a partnership with Eagle Rock Distributing Company, a wholesale partner of Anheuser-Busch.

09:30 EDT BetMGM launches NHL-branded casino games - BetMGM, a sports betting and iGaming operator, announced the launch of its National Hockey League-branded casino games including roulette, blackjack, baccarat and the new live Money Wheel game, Dream Catcher. All games are available to players in New Jersey, Ontario, Pennsylvania and Michigan, the company said in a statement. "The launch of these one-of-a-kind games further strengthens our relationship with the NHL," said Oliver Bartlett, BetMGM's Director of Gaming.

09:25 EDT CNH Industrial announces subsidiary notes offering - CNH Industrial announced that its wholly owned subsidiary, CNH Industrial Capital LLC, plans to offer new notes, subject to market conditions. The notes will be guaranteed by CNH Industrial Capital America LLC and New Holland Credit Company, LLC, each a wholly owned subsidiary of CNH Industrial Capital LLC. CNH Industrial Capital LLC is the North American arm of CNH Industrial's global financial services business. CNH Industrial Capital LLC intends to add the net proceeds from the offering to its general funds and use them for working capital and other general corporate purposes, including, among other things, the purchase of receivables or other assets in the ordinary course of business. The net proceeds may also be applied to repay CNH Industrial Capital LLC's indebtedness as it becomes due.

09:23 EDT Vicinity Motor secures order for four Vicinity Lightning electric buses - Vicinity Motor announced that it has received an order from strategic partner Sustainability Partners for four Vicinity Lightning electric buses via Soderholm Sales & Leasing, Vicinity's Pacific Islands distributor. The Vicinity Lightning shuttle buses will be used at the Daniel K. Inouye International Airport in Honolulu, the largest airport in the State of Hawaii serving 12 million passengers per year. The State of Hawaii Department of Transportation will utilize SP's Electric Vehicles as a Service program to finance the conversion of traditional government fleets to Vicinity's electric vehicles. Soderholm will facilitate the sale and provide long-term technical and maintenance support for the project. The order of four new electric buses is scheduled for delivery in 2023.

09:22 EDT Banxa Holdings initiates formal process to evaluate strategic opportunities - Banxa Holdings is initiating a formal process to identify and evaluate strategic opportunities to maximize shareholder value after it had received several unsolicited proposals to consider strategic M&A opportunities. The board of directors of the Company has appointed USA based Architect Partners, a leading cryptocurrency focused Investment Bank to ensure that shareholder value is maximized and to manage the process. The Company will update shareholders on any material changes of the proceedings. The Board will carefully evaluate all proposals and determine the path forward that is in the best interests of the company and all its shareholders. There can be no assurance that any definitive agreement will be completed, and all proposals are preliminary and non-binding.

09:20 EDT Walmart agrees to acquire Alert Innovation; terms not disclosed - Walmart announced that it has agreed to acquire Alert Innovation, a robotics automation company that develops material-handling technology for automating order fulfillment in retail supply chains. David Guggina, Senior Vice President of Innovation and Automation, Walmart U.S., commented that "Walmart has been working with Alert to customize technology for our MFCs since 2016. Further investing in this technology will enable us to leverage our store footprint - 4,700 stores located within 10 miles of 90% of the U.S. population - for storage and fulfillment... Looking ahead, we will continue to modernize our supply chain operations through investments in robotics and automation in our stores and distribution and fulfillment centers, creating exciting new experiences for customers that are unique to Walmart." Terms of the deal have not been disclosed. Reference Link

09:17 EDT ReElement takes possession of battery element purification equipment - American Resources Corporation announced that its majority-owned ReElement Technologies LLC division has procured the necessary equipment for its initial battery element isolation and purification production train for the production of battery-grade materials at its critical minerals purification facility in Noblesville, Indiana. Over the course of the last two months, ReElement has been focused on designing and building its initial battery production train while also scaling its internal capabilities of preprocessing and post processing of material so that 100% of the recycling process can be completed internally. ReElement has brought in house 100% of its leaching process, which will increase its capacity by over 30 times its initial capacity with its university partners. Additionally, the Company has also been expanding its first REE magnet production line at its Noblesville, Indiana facility by over 50% which recently announced commercial scale success in achieving greater than 99.5% pure isolated rare-earth elements.

09:16 EDT Duos Technologies Group appoints Matt Keepman as SVP, sales, marketing - Duos Technologies Group announced the appointment of Matt Keepman as its Senior Vice President of Sales and Marketing. In this newly created role Keepman will report directly to CEO Chuck Ferry and will be responsible for leading the Company's commercial strategy with a focus on driving top line growth. . Most recently he was a Key Account Executive for Wabtec Corporation where he led the commercial strategy for the Canadian Pacific Railway across all of Wabtec's business segments. Keepman will be tasked with advancing Duos Technologies' go-to-market strategy as it expands its offerings to private railcar owners, lessors, and shippers via inspection data subscription plans. He will also assist the executive leadership team in communicating the broader commercial strategy to internal and external stakeholders while further building out the infrastructure for both the sales and marketing teams.

09:12 EDT Kyndryl Holdings, Microsoft announce plans to expand partnership - Kyndryl (KD) and Microsoft (MSFT) announced plans to expand the reach and impact of their global strategic partnership by helping customers expand and increase access to valuable mainframe data. Kyndryl, provider of the secure multi-tenant zCloud, is applying its expertise to create data pipes that enable connections between the mainframe, including its zCloud platform, and the Microsoft cloud. Kyndryl and Microsoft also plan to combine mainframe data with other internal and external cloud-based data sources that will enable customers to create new applications that leverage modern analytics and visualization tools to deliver advanced insights at scale.

09:11 EDT Hyperfine appoints Maria Sainz as president, CEO - Hyperfine named Maria Sainz as President and CEO of Hyperfine, effective October 24, 2022. Scott Huennekens, who currently serves as interim President and CEO, will stay on as Executive Chairperson of the Board. Ms. Sainz has held President and CEO positions at multiple medical device companies in her industry tenure, including AEGEA Medical, acquired by CooperSurgical in 2021, Cardiokinetix, and Concentric Medical, acquired by Stryker in 2011.

09:10 EDT Backblaze appoints Robert Fitt as CHRO - Backblaze announced that Robert Fitt has joined the company as Chief Human Resources Officer. Fitt will lead the company's strategic advancement for all human resource functions, including talent management, culture, compensation and benefits, organizational design, health and wellness, and diversity, equity, and inclusion efforts. Fitt has held HR leadership roles at Turntide Technologies, 360 Behavioral Health, Mobilite, Broadcom Corporation, and others

09:08 EDT Steakholder Foods files provisional patent application for fat differentiation - Steakholder Foods has filed a provisional patent application with the USPTO regarding methods and systems for adipocytes differentiation. The patent application details a new process for differentiating stem cells into fat - increasing cultivated fat yields from stem cells -, which is designed to be more easily reproducible and cost-effective than current methods. To date, Steakholder Foods' patent portfolio, fully owned by Steakholder Foods group companies, includes a granted patent and 15 patent applications.

09:07 EDT LPL Financial financial advisor launches Resonate Wealth Partners - LPL Financial LLC announced financial advisor Alexander "Alex" Guiliano, CFA, has launched a new independent practice, Resonate Wealth Partners, through affiliation with LPL Strategic Wealth Services, a modern breakaway solution for advisors seeking to gain control over their business. Guiliano reported having served approximately $1 billion in advisory, brokerage and retirement assets*, and joins LPL from Merrill Lynch.

09:07 EDT Abbott's FreeStyle Libre 2 system shows efficacy in published diabetes study - Abbott's FreeStyle Libre 2 glucose monitoring system was featured in a new study published in The New England Journal of Medicine which finds that for adults with Type 1 diabetes and sub-optimal glycemic control, Abbott's glucose monitoring system provided significant reductions in glycated hemoglobin compared to self-monitoring of blood glucose, which were sustained for the study duration of 24 weeks. Use of the FreeStyle Libre 2 system was also linked to improvements in participant-reported quality of life outcomes, including overall satisfaction and reduction in burden associated with glucose monitoring. After six months, people who used the FreeStyle Libre 2 system reduced their HbA1c levels by an average of 0.8%. In comparison, people using SMBG reduced their HbA1c levels by an average of only 0.2%. HbA1c provides an estimate of average glucose levels over the preceding three months and is the standard measurement of glycemic control for people with diabetes. The average HbA1c level of participants using the FreeStyle Libre 2 system was 0.3% lower at 12 weeks and 0.5% lower at 24 weeks, statistically significant compared to those using SMBG. At 24 weeks, these participants reported greater overall treatment satisfaction and reduced burden associated with glucose monitoring. Abbott was not involved in the execution or funding of the study.

09:06 EDT XFuels announces Cycle Oil & Gas purchase of property, oil leases - Xfuels announces Cycle Oil & Gas has closed its purchase of Ray Loveless Enterprises LLC & R.L. Gathering of Allen, Texas in an all-cash deal consisting of 10 leases, 106 wells, 10 oil batteries, 3 Acre industrial yard & Shop, & Equipment in Wichita County, TX. Cycle paid $250,000 dollars plus a 2.5 % capped ORRI to $325,000 dollars for a total purchase price of $575,000. Adjacent to the "Ray Loveless" leases are 3 of the "Triple S Gas" leases that Cycle purchased and disclosed on September 29, 2022. The 13 combined leases "RLE & Triple S" fall within a 6 square mile radius that Cycle Oil & Gas will work to develop a workover program to bring nearly 80 shut-in wells back online through the use of their own rigs & licensed technologies. Cycle sees this as a prime opportunity to cut fuel costs & mob times on their service rigs from well to well, while increasing production and lowering lease operating expenses bottom line.

09:05 EDT FuboTV, Altitude Sports announce multi-year carriage agreement - FuboTV and Altitude Sports, the regional sports network, or RSN, home to the Stanley Cup champion Colorado Avalanche and Denver Nuggets, announced a multi-year carriage agreement that will expand TV coverage of both teams. Altitude Sports will be available to FuboTV subscribers in 10 Rocky Mountain states just ahead of the 2022-2023 NHL and NBA seasons. Fubo will stream Altitude Sports' coverage of the Denver Nuggets, the Colorado Avalanche and the Colorado Mammoth.

09:04 EDT Industry partnership announces pilot to decarbonize construction waste - Lendlease, Rubicon Technologies Mycocycle, and Rockwood Sustainable Solutions announced the completion of a successfully partnered pilot involving used asphalt shingles, mushrooms, and mycoremediation technology to reduce construction and demolition waste in order to produce a sustainable and reusable product to further create a more circular economy. According to the Environmental Protection Agency, 11 to 13 million tons of asphalt shingles end up in landfills each year, where they take upwards of 300 years to break down. After seeing the large percentage of waste that was generated by used asphalt roofing shingles from a recent re-roofing project at their Fort Campbell Army installation in Kentucky, Lendlease, Rubicon, Mycocycle, and Rockwood Sustainable Solutions proposed a solution to reuse the material in a new capacity. "Every asphalt shingle from those 214 homes would have gone to a landfill," said Sara Neff, Head of Sustainability at Lendlease Americas. "There was simply no viable use for them. We understand the importance of reducing our Scope 3 carbon by diverting waste streams from the landfill. After teaming up with Rubicon, Mycocycle, and Rockwood Sustainable Solutions, we came up with an innovative idea using mycoremediation technology; combining mushrooms and shingles to break down waste materials and create a new by-product that could ideally be reintroduced for reuse, furthering a circular economy."

09:03 EDT Amgen opens new R&D site in San Francisco's Oyster Point - Amgen announced the opening of a new research and development site in San Francisco's Oyster Point, continuing the company's nearly two-decade presence in the region. The new site will constitute the company's second largest research and development facility, which focuses on discovering therapeutics for patients living with cancer, inflammatory disease and cardiometabolic disorders. The centerpiece of the new site is a 245,000 square foot, nine-story building that will provide a workplace for 650 staff representing 24 different functions. The site features open work spaces and modular labs designed to encourage greater collaboration and teamwork, and meets high standards for environmental sustainability, having been submitted for LEED and FitWel-certification.

09:02 EDT Rackspace Technology launches cybersecurity micro site - Rackspace Technology has launched a new, dedicated cybersecurity micro site, in conjunction with National Cybersecurity Awareness Month, which takes place in October. This year, NCSAM is dedicated to strengthening security measures with the theme of "See Yourself in Cyber," and Rackspace's site is dedicated to helping organizations evolve their security postures in the multicloud era.

09:01 EDT Motus GI Holdings granted U.S. patent for prepless colonoscopy methods - Motus GI Holdings, announced the United States Patent and Trademark Office has issued the Company a new patent titled, "Cleaning Method for Prepless Colonoscopy."The new patent covers methods for clearing of fecal matter comprised of particles of various sizes and compositions from the wall of a colon or other body lumen for diagnostic inspection. These methods are further adapted for application in patients who have undergone a restricted scope of preparation to reduce and/or remediate the particle structure of colon contents, or no preparation prior to a colonoscopy. One of the key embodiments is matching the diet leading up to a colonoscopy with the capabilities suction and irrigation that a system like Pure-Vu provides to maximize the efficiency of the procedure. This includes avoiding several types of food that could yield particles resistant to active clearance from a colon through the Pure-Vu System, such as large seeds or highly fibrous vegetables. These simple diet modifications can be important for patients with comorbidities like diabetes to avoid complications due to low blood sugar or electrolyte imbalance that can happen during the typical 24 hours of clear liquid diet and consumption of purgative.

09:00 EDT Scorpio Tankers announces three time charter-out agreements - Scorpio Tankers announced that it has entered into three new time charter-out agreements.

09:00 EDT Shanda Games Limited(ADR) trading resumes

08:59 EDT Endava acquires Lexicon Digital and Lexicon Consolidated, terms undisclosed - Endava announced the acquisition of Lexicon Digital and Lexicon Consolidated, headquartered in Melbourne, Australia. Lexicon is an Australian-based technology consulting, design and engineering firm who partners with clients to build new digital solutions or accelerate digital transformation programs across enterprise systems, products and IoT using an agile delivery methodology. Lexicon's clients include Australia's market leaders in the insurance and wealth management sectors and an array of companies in other sectors, including entertainment, retail, agribusiness and automotive. In the year ending June 30, 94% of Lexicon's revenue was from Australian clients and 6% from the USA, with close to 90% of revenue from large corporates. Lexicon has 127 billable staff in Australia and Vietnam. The acquisition of Lexicon enhances Endava's existing presence in Australia and provides a strong foundation for accelerated in-market growth. In addition, Lexicon provides Endava with a nearshore delivery location in Vietnam which complements our existing operations in Singapore and Malaysia.

08:55 EDT Terminix shareholders approve agreement to be acquired by Rentokil - Terminix announced that its shareholders have voted at a special meeting of shareholders held to adopt and approve the previously announced agreement for Terminix to be acquired by Rentokil Initial. The acquisition is expected to close on October 12, subject to satisfaction of customary closing conditions.

08:54 EDT Standard BioTools launches X9 Real-Time PCR System - Standard BioTools announced the launch of the X9 Real-Time PCR System, an innovative high-capacity genomics instrument offering superior efficiency. X9 enables high data output with more than 9,000 individual nanoliter-volume reactions in a single run, ensuring cost-effective, comprehensive sample profiling with minimal operator contribution. Instead of using 96 plates worth of reagents, plastic and labor, X9 can reduce an experiment to a single integrated fluidic circuit - a microfluidic chip. The X9 platform, powered by single-touchpoint operation, streamlines laboratory processes by integrating reaction setup into an automated workflow that generates up to 46,080 datapoints per 8-hour shift.

08:52 EDT Acer, University of North Carolina receive DoD grant for ACER-801 trial - Acer Therapeutics announced that the University of North Carolina Institute for Trauma Recovery has been awarded a $3 million grant from the Department of Defense to investigate the potential of ACER-801 to reduce the frequency and severity of acute stress disorder and post-traumatic stress disorder. Acute stress disorder refers to the body's immediate response to trauma, whereas PTSD is the long-term effects of trauma. The proposed Osanetant After Stress to Increase recovery Success trial will examine the safety and efficacy of ACER-801 to reduce acute stress response symptoms, post-traumatic stress disorder symptoms and behavioral changes among patients presenting to the emergency department after a motor vehicle collision. It is intended to enroll a total of 180 subjects who will be randomized in the emergency department, to receive a low or high dose of ACER-801 or placebo in the emergency department and be discharged with a two-week supply of study drug. Participating sites would include Washington University in St. Louis, University of Massachusetts Chan Medical School, Rhode Island Hospital, University of Florida College of Medicine - Jacksonville, and Indiana University School of Medicine. Initiation of patient enrollment in the proposed investigator sponsored OASIS trial is anticipated in the first half of 2023, subject to Investigational New Drug application filing and U.S. Food and Drug Administration clearance.

08:49 EDT DoorDash partners with Marvel Entertainment to launch "The Dashers" comic book - DoorDash announced a partnership with Marvel Entertainment to create exclusive, custom content inspired by and created for Dashers. Introduced at New York Comic Con, DoorDash and Marvel worked together to launch a new custom comic book, The Dashers, which celebrates the work and lives of those who deliver with DoorDash. The comic book depicts how four Dashers are able to save the city of "Dashville". In addition to the comic book release, Marvel will bring The Dashers to life in a motion comic series that will be released in five chapters.

08:49 EDT Surgalign reports inducement grants under Nasdaq listing rule - Surgalign Holdings announced that it has granted restricted stock unit awards to two employees, none of whom was an executive officer, as an inducement for them to accept employment with Surgalign, and representing the right to receive, in the aggregate, up to 10,081 shares of Surgalign common stock. The award was granted on October 03, 2022 and it was made under the Surgalign Holdings, Inc. 2021 Inducement Plan. One-third of the restricted stock units vest on the first anniversary of the date of grant, and one-eighth of the remaining restricted stock units vest on each subsequent quarterly anniversary of the date of grant, such that the award will be fully vested on the third anniversary of the date of grant, subject to continued employment through the applicable vesting date. The awards were approved by the independent Compensation Committee of the Board of Directors of Surgalign Holdings and were granted to the new employees as an inducement material to their acceptance of employment with Surgalign pursuant to Nasdaq rules.

08:47 EDT Provention Bio jumps 16% after announcing co-promotion pact with Sanofi US - Shares of Provention Bio (PRVB) are up 16% or 79c per share at $5.74 in pre-market trading after Sanofi US (SNY) confirmed a co-promotion pact with Provention Bio to launch teplizumab.

08:43 EDT KULR Technology acquires VibeTech, launches KULR VIBE service - KULR Technology Group announced its acquisition of VibeTech and the formal launch of KULR VIBE, an AI driven vibration reduction solution. KULR VIBE addresses one the most challenging issues with advanced machinery today; excessive energy robbing vibrations that are destructive to both the machinery and in many cases the operator. The KULR VIBE suite of technologies utilize proprietary sensor processes with advanced learning algorithms to both achieve precision balancing solutions, and successfully predict component failure based on its comprehensive database of vibration signatures. Its enhanced AI learning algorithms pinpoint areas where excess vibrations cause a loss of energy that can lead to system malfunctions, weakened performance, and maintenance issues. The KULR VIBE suite of products and services have provided vibration analysis and mitigation to global companies across multiple industries and sectors. Advances in measurement and computing have allowed the KULR VIBE technologies to provide transformative, scalable solutions across aviation, transportation, renewable energy, manufacturing, industrial, performance racing and autonomous aerial applications.

08:41 EDT Sypris Solutions awarded expanded scope on electronic warfare program - Sypris Electronics a subsidiary of Sypris Solutions announced that it has entered into an amendment to an existing multi-year supply agreement to include the production of electronic power logic assemblies for a large, mission-critical Navy program. The amended contract, including options, now provides for the purchase of up to $77M of assemblies from Sypris over the term of the agreement, representing a 39.5% increase in potential volume when compared to the original base contract announced earlier this year. In conjunction with the amendment, Sypris also received releases for the first year of production, with shipments scheduled to begin in 2023. Additional terms of the contract were not disclosed. The modules to be produced by Sypris will be integrated into an electronic warfare improvement program for the U.S. Navy. According to news sources, the upgrade will provide the capability to actively jam incoming missiles that threaten a warship, cue decoys, and adapt quickly to evolving threats. The improvements to the electronic attack portion will provide integrated countermeasures against radio frequency-guided threats, according to the Navy.

08:41 EDT HCA Healthcare expands partnership with Tennessee State University - HCA Healthcare announced that it will give $1.5M to Tennessee State University, or TSU, to create scholarship opportunities for students enrolled in the Dr. Levi Watkins, Jr. Institute and the Department of Computer Science within the College of Engineering. This gift is part of the organization's larger commitment to give $10M over three years to Historically Black Colleges and Universities and Hispanic Serving Institutions. Since making the pledge in 2021, HCA Healthcare has announced approximately $5.25M in donations towards multiple partnerships.

08:38 EDT Alcoa in wind power purchase pact to support restart of San Ciprian smelter - Alcoa announced an additional power purchase agreement to support the future restart of the San Ciprian aluminum smelter in Spain. This latest agreement is with Endesa, a leading company in the Spanish electricity sector that is a subsidiary of the Enel Group. The agreement will provide power balancing services for the smelter load from 2024 to at least 2030. Balancing services provide electricity to the smelter's consumption point, either from baseload volumes from a power purchase agreement with Endesa, via other third-party agreements, or from the market directly. The agreement with Endesa would include up to 131 megawatts beginning in the second half of 2025 and through 2033, representing slightly more than 30% of the smelter's energy requirements at maximum capacity. The final volume and start of the baseload power deliveries can be adapted as the process to develop windfarms evolves. The pricing terms are confidential. "This agreement demonstrates Alcoa's efforts to find a viable solution for the San Ciprian smelter," said Alvaro Dorado Baselga, Vice President Global Energy in Alcoa and President of Alcoa in Spain. "While the energy agreements represent important progress, the success of the smelter will depend on the development of a long-term competitive power framework in Spain and getting the permitting process approved for these windfarms." The agreement with Endesa will supplement the terms of a separate agreement reached earlier this year with Greenalia for up to 183 megawatts. That agreement, which is subject to windfarm permitting process, would represent approximately 45 percent of the energy required to meet the smelter's maximum capacity. Together, the agreements with Endesa and Greenalia could provide up to approximately 75% of the smelter base load power. Alcoa is continuing to pursue options for the remaining 25 percent of the smelter's electricity requirements. Due to exorbitant energy prices, Alcoa announced in December 2021 a two-year curtailment of aluminum smelting at the San Ciprian smelter. During the curtailment, Alcoa is working to secure power purchase agreements and make improvements to prepare for the future restart.

08:37 EDT Spirit announces proxy firms recommend shareholders vote for JetBlue merger - Spirit Airlines (SAVE) announced that independent proxy advisory firms Institutional Shareholder Services, or ISS, and Glass Lewis have recommended that Spirit stockholders vote for the merger agreement with JetBlue (JBLU).

08:36 EDT Opiant Pharmaceuticals completes enrollment in Phase 2 trial of OPNT002 - Opiant Pharmaceuticals announced that the last patient has been enrolled in the Phase 2 clinical trial of OPNT002, nasal naltrexone, for patients with Alcohol Use Disorder. The total trial duration per patient is 20 weeks, with the last patient enrolled expected to complete the study in early 2023 and with top line data anticipated to follow mid-year.

08:35 EDT KKR to purchase majority interest in Boasso Global, terms undisclosed - Funds advised by Apax Partners and KKR announced the signing of a definitive agreement under which the Apax Funds will sell their majority interest in Boasso Global, a provider of depot, maintenance, cleaning, and transportation services for the ISO tank container industry in North America and Europe, to KKR. KKR is making the investment in Boasso through its KKR Global Infrastructure Investors IV fund, which focuses on critical infrastructure investments in North America and Western Europe. Financial terms of the transaction were not disclosed. Boasso provides logistics services to the global chemical and food grade supply chains through a network of 34 located depots across North America and Western Europe.

08:33 EDT Taoping announces strategic framework contract worth $3M - Taoping announced that it entered into a strategic framework contract with an estimated value at $3M. Under the agreement, over the next six months the company will leverage Taoping's smart cloud platform and the cloud-based ad terminal network of Taoping Alliance to provide digital advertising services to Shenzhen Taitao Electronic Technology Co., Ltd., an electronic component solutions provider headquartered in Shenzhen, China.

08:31 EDT Durect achieves enrollment milestone in Phase 2b AHFIRM trial - Durect announced the enrollment of more than 200 of the planned 300 patients in its Phase 2b AHFIRM trial. The AHFIRM trial seeks to evaluate larsucosterol's potential to serve as a treatment for severe alcohol-associated hepatitis.

08:28 EDT Aemetis closes $25M USDA guaranteed project financing - Aemetis announced the closing of $25 million of long-term financing with Greater Commercial Lending, which provides loans to businesses and organizations in under-served and rural communities, to build dairy biogas digesters and a biogas pipeline for the Aemetis Biogas Central Dairy Digester Project located in Stanislaus County, California. The long-term, 20-year project financing was guaranteed by the U.S. Department of Agriculture through the Rural Energy for America Program and carries approximately a 6% fixed interest rate for the first five years. Methane digesters are systems that promote the decomposition of organic matter, including animal manure, food wastes and wastewater biosolids, into renewable fuels to replace petroleum products. The Aemetis biogas project is a collection of anaerobic digesters at dairy farm lagoons that utilize waste animal manure to generate renewable methane gas to produce renewable natural gas. The construction and testing of the six dairy biogas digesters funded by the USDA guaranteed loan is scheduled for completion in Q1 2023. A biogas pipeline connects the dairies to the Aemetis Keyes ethanol plant, where the biogas will be converted to low carbon RNG to be used as a transportation fuel. In addition to using the RNG at the Aemetis ethanol plant and the onsite RNG fueling station that is being built, Pacific Gas & Electric will deliver the transportation fuel via gas pipeline throughout California for sale to customers.

08:25 EDT The Oncology Institute expands into South Florida - The Oncology Institute announced its entrance into South Florida with the acquisition of Broward Oncology Associates located in Fort Lauderdale and the opening of a new clinic in Plantation.

08:24 EDT Beam Global delivers 23 EV ARC charging systems to R&D centers - Beam Global announced that another 23 EV ARC systems have been delivered to Federally Funded Research and Development Centers. The latest systems were purchased using the General Services Administration Multiple Award Schedule Contract Number 47QSWA21D0006 which simplifies the federal procurement process and ensures best pricing.

08:23 EDT Tempest Therapeutics to present on TREX1 at Emerging Technologies summit - Tempest Therapeutics announced that Dara Burdette, Ph.D., Senior Director of Discovery Research at Tempest, will present on the company's TREX1 pipeline asset and will serve as chairperson for the "New Approaches to Solid Tumor Targeting" session at the Emerging Technologies for IO Targeting and Discovery Summit taking place October 13-14, 2022 in Boston, MA. TREX1 Presentation: Dr. Burdette's presentation will describe the company's approach to identify and characterize novel small molecule inhibitors of the 3'-5' DNA repair exonuclease, TREX1. TREX1 inhibits cGAS/STING signaling and is induced in tumor cells due to genetic instability or therapeutic intervention. Tempest's program aims to generate an anti-tumor response through selectively activating the STING pathway in advanced metastatic cancers with orally available small molecule inhibitors of TREX1. TPST-1495 Presentation: In addition, Nicholas DeVito, M.D., a medical oncologist and medical instructor in the laboratory of Dr. Brent Hanks, M.D., Ph.D. at Duke University School of Medicine, will be giving a presentation describing pre-clinical results with TPST-1495, Tempest's clinical-stage dual inhibitor of the EP2 and EP4 prostaglandin E2 receptors, in mice bearing tumors with designated gene expression profiles.

08:20 EDT CommAgility introduces capability for intra-PHY handover - Wireless Telecom Group announced that its CommAgility brand has introduced a capability for intra-PHY handover across two frequencies to its 5G systems, for straightforward spectrum sharing and frequency collision avoidance. This new capability, an industry first from any independent software vendor, allows a 5G connection to seamlessly move from one carrier frequency to another without interruption of the services. This is important in frequency bands where there is interference from Wi-Fi, radar, or other signals, such as is the case with New Radio Unlicensed and in the CBRS band. The Intra-PHY 5G handover capability will also enable first responders and emergency services to set up temporary 5G networks quickly and simply, while automatically avoiding occupied spectrum interference.

08:18 EDT Cyclerion Therapeutics announces workforce reduction of 45% - The Company's workforce is being tailored to the mitochondrial disease-focused strategy, leading to a reduction of approximately 45%, to 16 full-time employees. The Company expects to take an aggregate charge for one-time employee-related costs of approximately $1.9 million that is expected to be incurred primarily in Q4 2022 and realize annual cash savings of approximately $4.1 million.

08:16 EDT Crinetics announces Innovation Passport granted to CRN04777 - Crinetics Pharmaceuticals announced today that the UK Medicines and Healthcare products Regulatory Agency has granted CRN04777 an "Innovation Passport" for the treatment of congenital hyperinsulinism, which enables Crinetics to access the Innovative Licensing and Access Pathway. The ILAP was launched in the United Kingdom in 2021 with the goal of reducing the time to market for innovative medicines that treat life-threatening or seriously debilitating conditions and/or conditions for which there is a significant unmet patient need. The ILAP aims to achieve this goal by enabling enhanced coordination between sponsors and MHRA leading up to Marketing Authorization Application submissions and by providing the opportunity for accelerated MAA reviews.

08:14 EDT Alimera Sciences says ILUVIEN patients show reduced need for multiple treatments - Alimera Sciences announced that post-hoc analyses from the PALADIN Phase 4 Safety Study demonstrate that median treatment frequency in diabetic macular edema patients treated with the ILUVIEN 0.19 mg was lower than from patients on other regimens. ILUVIEN provides DME patients with continuous therapy for up to 36 months. As part of the PALADIN phase 4 study, investigators sought to quantify the treatments required by eyes prior to ILUVIEN and after injection of ILUVIEN. ILUVIEN treatment significantly reduced the number of eyes requiring anti-VEGF, corticosteroid, and laser therapy and reduced the total number of therapies administered by 46%. 25% of eyes remained supplemental treatment free through 36 months. Also of note, PALADIN phase 4 data demonstrate ILUVIEN patients experienced on average an increase in visual acuity, a significant decrease in retinal thickness and a predictable and manageable safety profile over 36 months. Combined with the evidence from prior studies, the PALADIN study data further support ILUVIEN's value as a durable DME therapy. ILUVIEN is a sustained release intravitreal implant indicated in the United States for the treatment of diabetic macular edema in patients who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in intraocular pressure.

08:12 EDT DZS introduces DZS Saber-4400 platform - DZS announced the introduction of its DZS Saber-4400 compact, modular, coherent optical metro and edge transport platform architected for convenient, cost-effective delivery of fiber-based services at speeds of up to 400 Gigabits per second per wavelength and multi-degree CDC Flex ROADM functionality. Each 1 Rack Unit DZS Saber-4400 shelf features 4 hot-swappable modules for extensive flexibility and expandability and delivers an industry-first portfolio of environmentally hardened Dense Wave Division Multiplexing modular transponder and muxponder solutions capable of operating between -40 degrees C to +65 degrees C while delivering 100 Gbps+ circuits up to 120 kilometers without amplification.

08:10 EDT Galectin Therapeutics says DSMB concludes NAVIGATE can continue as designed - Galectin Therapeutics reported the outcome of its second data and safety monitoring board meeting for NAVIGATE, its seamless, adaptive, phase 2b/3 study of belapectin in patients with liver cirrhosis caused by non-alcoholic steatohepatitis. NAVIGATE is the first study of its kind and is a global effort that recruits patients in over 15 countries and five continents. The main efficacy objective is the primary prevention of esophageal varices. Patients enrolled in the study have liver cirrhosis caused by NASH and, because of the advancing cirrhotic process, have already developed portal hypertension but have not yet developed esophageal varices as a complication of portal hypertension. Portal hypertension is the consequence of the unrelented inflammatory and fibrotic process occurring in the liver and dramatically increases the risk of developing esophageal varices, a potentially life-threatening complication of liver cirrhosis. The objective of this second independent DSMB was to further review the emerging tolerance and safety profiles of belapectin. Based on its deliberation, the DSMB concluded that NAVIGATE can continue as designed, without modifications.

08:09 EDT Guardion Health announces clinical results on Viactiv Omega Boost Gel Bites - Guardion Health Sciences announces interim four-week results of a clinical study designed to evaluate the effectiveness of new Viactiv Omega Boost Gel Bites at increasing Omega-3 saturation levels on red blood cells. The 1,200 mg Omega-3 gel bites contain both DHA and EPA and are designed to provide total body support, including cardiovascular, brain, immune and eye health. The new gel bite dosage form provides the potency of large, hard-to-swallow soft gels, in a great tasting chewable format that has more than ten times the amount of Omega-3s than the leading omega-3 gummy. The gel bite delivery has no sugar and no unpleasant fishy aftertaste.

08:07 EDT AMMO clarifies spin-off metrics - AMMO has been fielding questions in follow up to the earlier announced planned separation of the manufacturing and marketplace business operations into two separate public companies. The Company confirms for all AMMO shareholders that, upon completion of the separation, each current shareholder of AMMO will own one share of Outdoor Online, Inc., comprised of GunBroker.com and its related online businesses, and one share of Action Outdoor Sports, Inc., the Company's current ammunition and munition components business.

08:05 EDT Evogene to Present at LD Micro Main Event XV investor conference in LA - Evogene announced that Ofer Haviv, Evogene's President and CEO, will attend and present at LD Micro Main Event, an investor conference taking place from Tuesday, October 25 to Wednesday, October 26, in Los Angeles. The event is a leading small cap investor conference, showcasing over 200 small- and micro-cap companies.

08:05 EDT Uber and Motional enter commercial agreement for driverless ride services - Uber Technologies and Motional, a global driverless technology company, announced a commercial agreement to offer fully driverless rides using Motional's new all-electric IONIQ 5-based robotaxis. The 10-year, multimarket agreement pairs Motional's driverless technology with Uber's network of customers. The companies will strategically deploy the service in cities across the U.S., with the first trips expected to start later this year. Uber will share targeted insights to efficiently allocate and position Motional's vehicles. Earlier this year, Motional began conducting autonomous food deliveries for Uber Eats customers in California. Motional and Uber have since expanded their delivery operations to service more restaurants. Motional is now positioned to become the first autonomous vehicle company to offer both delivery and ride-hail services within a major network like Uber. Motional's IONIQ 5 robotaxis are fully electric, zero tailpipe-emissions vehicles.

08:04 EDT Orion Energy acquires Voltrek, terms not disclosed - Orion Energy Systems announced its expansion into the electric vehicle charging station market through the acquisition of Voltrek, LLC. Voltrek had 2021 revenue of $4.8M primarily from projects in New England.Voltrek provides turnkey EV charging solutions and ongoing support to all commercial verticals, working as a value-added resale partner to leading Electric Vehicle Supply Equipment and Electric Vehicle Service Providers, offering turnkey solutions from planning and installation to maintenance and management services. Voltrek will operate with its existing employees as an independent brand within Orion. The acquisition positions Orion in the fast-expanding EV charging infrastructure market. BloombergNEF estimates global passenger EV sales will rise from 6.6M units in 2021 to an estimated 20.6M units in 2025, driving substantial demand for EV charging infrastructure. Approximately $5B in state and federal programs have been developed to incentivize consumer adoption and support the buildout of EV charging infrastructure over the next five years through the National Electric Vehicle Infrastructure Formula Program established by the Bipartisan Infrastructure Law.

08:01 EDT Shell sees Q3 integrated gas results significantly lower than Q2 - Shell provided an update to the third quarter outlook. Integrated gas production is expected to be between 890 and 940 thousand barrels of oil equivalent per day. LNG liquefaction volumes are expected to be between 6.9M and 7.5M tons. Trading and optimization results for Integrated Gas are expected to be significantly lower compared to the second quarter 2022 as a result of seasonality and substantial differences between paper and physical realization in a volatile and dislocated market. Underlying Opex is expected to be between $1.1B and $1.3B.

07:58 EDT Draganfly to showcase Commander 3 XL drone at IACP conference - Draganfly announced its involvement in The International Association of Chiefs of Police Annual Conference and Exposition from October 15-18, 2022. During the four-day event, Draganfly will be located at booth #2928, where attendees can learn about the Company's Commander 3 XL drone and Smart Vital Intelligence technology. Draganfly's Commander 3 XL, known as the "Swiss Army Knife" of drones, is a high-endurance, weather-resistant, multirotor UAV designed for easy assembly and rapid deployment. Draganfly will showcase its Smart Vital Intelligence technology, which can utilize cameras on its drones, kiosks, or mobile devices to provide real-time health insights in seconds.

07:55 EDT Arena Minerals to acquire 2,000 hectares adjacent to R-01 discovery - Arena Minerals is pleased to announce that its subsidiary Sal de la Puna Holdings has entered a binding Letter of Intent to acquire five mining claims covering 2,200 hectares of the Pastos Grandes basin, located in Salta province, Argentina. Three of these claims, covering a total of 2,000 hectares, lie immediately adjacent to the Fortuna II claim block where the Company recently discovered a 275-metre brine aquifer averaging 441 milligrams per litre lithium. This eastern sub-basin of Pastos Grandes is interpreted as extending south on to the newly acquired claims, potentially hosting the continuation of the discovered brine bearing aquifer. The new claims will form part of the Company's Sal de la Puna lithium brine project, which upon closing will cover 13,200 hectares of the Pastos Grandes basin in Argentina. Pursuant to the terms of the LOI, SdlPH's 100% owned Argentine subsidiary, Puna Argentina, will enter into a definitive Sale and Purchase Agreement to acquire 100% title over three claim blocks and lithium brine rights over an additional two claim blocks covering a total of 2,200 hectares. The vendor is a local, arms length privately owned company and will not be receiving any shares of the Company as part of the transaction. Total consideration of $3,825,000 shall be paid to the vendor, as follows: a first installment of $350,000 on signing of the Agreement; a second installment of $825,000 on signing of the public deed required by law to instrument the transfer of mines, which will take place 60 days after the signing of the Agreement or when the designated notary public obtains title certificates free of debt, whichever occurs first; a third installment of $1,350,000 12 months after signing the Agreement; and the fourth and last installment of $1,350,000 24 months after signing the Agreement. As collateral for the payments of the second and third installments, PASA will grant a mortgage guarantee in favour of the vendor on the Fortuna I, Cerrana and Betina claims. The Agreement will supersede the LOI and is expected to be signed within the next fifteen days. Execution of the Deed required by the Argentine Federal Mining Code to complete the transfer of three claims and closing of the transactions contemplated by the Agreement is expected to take place on or before December 31, 2022. Together with the execution of the Deed, PASA will enter a Bilateral Usufruct Agreement with the vendor in which usufruct rights to explore and exploit the lithium bearing brines over the Sol de Manana and Dona Pancha claims shall be conceded in favour of PASA. In the same agreement PASA shall concede the vendor similar rights over any solid state borates contained within the acquired Fortuna I, Cerrana and Betina claims. The Bilateral Usufruct Agreement will be subject to the maximum term recognized by the Argentine Federal Mining Code of 40 years, and to the usual conditions of mutual and reciprocal indemnity against any damage or claim that either Party may suffer for the operations undertaken by the other Party on site, including obligations to undertake such operations in compliance to any applicable legislation, labour and environmental laws. Sal de la Puna Holdings Inc is registered in Canada and is jointly owned by Arena and Ganfeng New Energy Technology Development (GNENF). SdlPH owns 100% of PASA, incorporated in Argentina, which in turn owns 100% of the Project.

07:51 EDT Vitalhub expands debt facility with Bank of Nova Scotia - VitalHub announced that the Company has amended its existing debt facilities with The Bank of Nova Scotia's Technology and Innovation division. Under the terms of the amendment, the Company's acquisition line has been expanded to $27 million up from $10 million. Additionally, the Company's operating line has been expanded to $6 million up from $1 million. Currently, the Company has drawn $9 million from the acquisition line.

07:48 EDT Tilt Holdings announces Massachusetts launch of Black Buddha Cannabis - TILT Holdings announced the Massachusetts launch of Black Buddha Cannabis, a Black and woman-owned and led, environmentally conscious, social impact driven cannabis wellness brand. Roz McCarthy is the driving force and founder of Black Buddha Cannabis, as well as Minorities for Medical Marijuana Inc. which advocates for equity and diversity in the nascent cannabis marketplace. Both organizations originated from the personal needs and experiences of McCarthy, who found cannabis instrumental to her healing journey after a car accident. Her brand seeks to promote optimal wellness across every aspect of life and support each patient or consumer to achieve their potential and live with passion and purpose. The initial experience-based product line, Blyss, could support euphoric and positive effects. The products are primarily built around a sativa-leaning, hybrid flower that creates an uplifting blissful feeling with an array of sweet aromas in the following offerings: Blyss Flower-an eighth of expertly grown, premium cannabis; Blyss Chyllum-a 100-percent recyclable glass chillum, packed with 0.35g of flower; and Blyss Vape-a vape containing 300mg of a 3:1 THC:CBD ratio that is rich in beta-caryophyllene. Black Buddha Cannabis is also expected to launch in the Pennsylvania market this fall through the brand's exclusive partnership with TILT.

07:46 EDT Ayr Wellness brings concentrates brand HAZE to Florida - Ayr Wellness is announcing the rollout of its premium live resin concentrates and vapes brand HAZE in Florida. Having recently celebrated surpassing 50 retail stores throughout Florida, the introduction of Hydrocarbon Extraction products to its menus marks another major milestone for Ayr in the Sunshine State. HAZE premium live resin concentrates and vapes are formulated for rapid onset and deliver a full-sensory experience. Products available at launch include live resin vape cartridges, live badder and live sugar. Strains include WAP #27, Caesar, 8" Bagel, Gorilla Glue, Mr. Nasty and Ruby Slippers.

07:42 EDT Constellation CEO says Q1 'another quarter of strong business performance' - CEO Bill Newlands said, "We delivered another quarter of strong business performance. Our core beer brands Modelo Especial and Corona Extra, continue to outshine the market and our next wave of brands, Pacifico and Modelo Chelada, are achieving strong double-digit growth. The benefits of our Wine and Spirits strategy are taking hold, as our higher-end brands continue to resonate with the consumer."

07:29 EDT Laser Photonics announces key highlights from recent IPO roadshow - Laser Photonics announces key highlights from its recent IPO roadshow. All information contained in this release are pursuant to a registration statement on Form S-1 that was declared effective by the U.S. Securities and Exchange Commission on September 29, 2022. The shares began trading on September 30, 2022, on the Nasdaq Capital Market under the ticker symbol "LASE." "Our IPO represents a major milestone in our strategy to disrupt the $46 billion global industrial market for removing rust and other materials," said Wayne Tupuola, chief executive officer of Laser Photonics. "Historically, extremely hazardous, dangerous and environmentally destructive abrasives and techniques such as sandblasting have been used for these applications. With our CleanTech Laser Blasting technologies, we offer products with superior performance to customers in a cost-effective and environmentally sustainable way to accomplish their MRO goals."

07:24 EDT Verizon Business enters partnership with Extreme Networks - Verizon Business (VZ) announced a partnership with Extreme Networks, Inc. (EXTR) to deploy wireless connectivity solutions at Liverpool FC's Anfield Stadium as part of Extreme's partnership with the Premier League club. The deployment, expected to begin later this year, includes Extreme Wi-Fi 6 access points which will provide the high-quality, low latency Wi-Fi connectivity required to power memorable, engaging fan-centric experiences such as mobile ticketing, cash free concessions, shopping at the team store, video streaming, and new digital immersive experiences.

07:21 EDT Green Thumb Industries appoints Richard Drexler, Jeff Goldman to board - Green Thumb Industries announced that Richard Drexler, who currently serves as Chairman of the Audit and Finance Committee at Bison Gear and Engineering, and Jeff Goldman, an entrepreneur with expertise in CPG brand-building, will join the Company's board of directors. Drexler will assume the role of Chair of the Audit Committee in this new capacity. The appointments follow the resignation of three board members, William Gruver, Glen Senk and Dorri McWhorter. The resigning directors informed management that their cause for resignation was not related to Green Thumb's business performance, operations, financial performance, financial statements or financial controls, but rather over a disagreement as to the Company's policies and practices related to personal misconduct. It became clear that the former directors and existing management could not find a resolution satisfactory to all parties.

07:15 EDT Agrify announces three rapid deployment program customer engagements - Agrify Corporation announced that Prairie State Cannabis LLC in Illinois, LowKey LLC in Massachusetts, and MediFlora Cultivation LTD in South Africa have all elected to operate their respective cultivation businesses using Agrify's Rapid Deployment Packs. As per the terms of the RDP agreements with Prairie State Cannabis LLC, LowKey LLC, and MediFlora Cultivation LTD, the combined agreements have an expected base value of over $7.5 million in cultivation-related hardware sales, and additionally include future recurring SaaS and production success fees. Agrify will initially be providing each customer with an RDP configuration consisting of 56 VFUs. With this infrastructure, each customer will have the potential to produce an estimated 7.5 pounds of premium quality flowers per VFU, per grow cycle, with approximately 5.2 grow cycles expected to be possible each year.

07:12 EDT Neximmune enters research collaboration with NINDS of the NIH - NexImmune announced a collaboration with the National Institute of Neurological Disorders and Stroke, a division of the U.S. National Institutes of Health. The collaboration will focus on enriching and expanding virus-specific T cell populations and determining their activity against infected human cell lines. The goal of this collaboration is to develop adoptive cell therapies that may benefit patients afflicted with immunological disorders related to these viral infections. Initially, we will focus our efforts on studying Epstein-Barr virus and Human T-cell Leukemia Virus, type 1.

07:11 EDT LanzaTech, Northwestern, Yale, NREL to establish center for synthetic biology - The U.S. Department of Energy recently announced $178 million for bioenergy research to advance sustainable technology breakthroughs that can improve public health, address climate change, improve food and agricultural production, and create more resilient supply chains. A team from Northwestern University, LanzaTech NZ, Yale University, and National Renewable Energy Laboratory received $18.5 Million in funding from this grant for integrating cell-free systems and genome engineering to accelerate biosystems design for carbon-negative biomanufacturing. With the DOE grant by the Office of Biological and Environmental Research Genomic Sciences Program, the research team will work to, Interweave in vivo and in vitro approaches, developing new Synthetic Biology tools and Artificial Intelligence models, Establish a predictive, system-level understanding of CO2-utilizing biosystems to accelerate sustainable biomanufacturing, and Engineer industrially relevant CO2-utilizing biosystems that produce advanced and performance-advantaged fuels and chemical precursors. The work will look to understand the fundamental rules that drive microbial systems and how they can make new products through biological design. This is expected to help support new approaches to biomanufacturing by developing performance-advantaged alternatives to materials, fuels, and solvents today exclusively made from virgin fossil inputs.

07:09 EDT Amazon is hiring 150,000 employees for the holidays - Amazon announced that it is hiring 150,000 employees throughout the U.S. in full-time, seasonal, and part-time roles across its operations network. A diverse range of roles-from packing and picking to sorting and shipping-are available to applicants from all backgrounds and experience levels. Employees can earn, on average, more than $19 per hour based on position and location in the U.S.

07:07 EDT Akoustis becomes charter member of Semiconductor Industry Association - Akoustis Technologies announced that it has joined the Semiconductor Industry Association as a Charter Member, alongside industry stalwarts including Intel, Micron, Qualcomm, AMD and others.

07:07 EDT Uber partners with Marqeta, MasterCard and Branch on Uber Pro Card - Uber (UBER) announced a new partnership with Marqeta (MQ), Mastercard (MA) and Branch to power the Uber Pro Card, an enhanced loyalty and payments experience that will help drivers and couriers save on gas, fees, and other expenses. Built for drivers and couriers, the Uber Pro Card offers customized perks including up to 10% cashback on gas and up to 12% on EV charging. Expanding the Uber Pro driver loyalty program, the Uber Pro Card offers Uber drivers and couriers up to 10% cashback on gas purchases when they achieve Diamond status as an Uber Pro driver, along with other exclusive perks and rewards. The card also comes with a business checking account powered by Branch and designed to enable drivers and couriers to keep more of what they earn. Drivers and couriers that sign up for the card can have their earnings automatically deposited into their Uber Pro Card account after every trip-free of charge. The Backup Balance feature allows drivers and couriers to access up to $150 when they need it most. The Uber Pro Card will be available via mobile wallets and enable contactless payments, so drivers and couriers can begin spending immediately. They can track earnings, transfer money to other bank accounts, earn rewards, and manage savings all through the Uber Pro Card app.

07:05 EDT Provention Bio and Sanofi enter co-promotion agreement for teplizumab - Provention Bio (PRVB) has entered into a co-promotion agreement with Sanofi (SNY) U.S. for the launch of Provention's lead investigational drug candidate teplizumab. The agreement enables Provention Bio to leverage Sanofi's expertise, capabilities and commercial resources to support the potential launch of teplizumab currently under review by the FDA for the delay of clinical type 1 diabetes in at-risk individuals, with a user fee goal date of November 17 for the Biologics License Application. Sanofi will commit commercial resources in the United States, including diabetes field specialists, account directors, field-based reimbursement and medical science liaisons to expand the number of key healthcare professionals reached in the U.S. In exchange, Provention will reimburse field force-related expenses that Sanofi will incur in connection with commercializing teplizumab under the agreement. Provention retains all rights to teplizumab and maintains responsibility for the commercialization strategy. The company also granted Sanofi, in consideration of a one-time payment of $20M, an exclusive, one-time right of first negotiation (to obtain exclusive global rights to commercialize teplizumab for Type 1 diabetes indications in humans. Sanofi may exercise the ROFN, until June 30, 2023, with an option to extend within 2023 under certain conditions. If teplizumab is approved by the FDA, Sanofi has agreed to purchase $35M of the company's common stock at a premium. The closing date will be at Provention's discretion and would occur no later than February 16, 2023.

07:03 EDT Calyxt announces agreement with Evologic Technologies - Calyxt announced that it has signed an agreement with its first manufacturing partner, Evologic Technologies GmbH, to further develop and scale Calyxt's proprietary Plant Cell Matrix technology platform. The agreement supports the continued build-out of Calyxt's plant-based synthetic biology capabilities. Evologic's contract development and manufacturing services, based on its proprietary bioprocess platform and technology, support companies delivering unique and sustainable bioproducts. Under the terms of the agreement, Evologic will work alongside Calyxt to grow and scale Calyxt's proprietary PCM technology. Specifically, Evologic will advance the manufacturing of PCM-derived compounds and establish proof of concept for the subsequent scaling of multiple PCMs simultaneously for commercial production.

07:02 EDT Entera Bio announces FDA agreement for single Phase 3 trial for EB613 NDA - Entera Bio announced theconclusion of its Type C meeting and agreement from the U.S. Food and Drug Administration that a single Phase 3 placebo-controlled study could support a New Drug Application submission of EB613 under the 505(b)(2) regulatory pathway. The FDA also agreed that Total Hip Bone Mineral Density could serve as the primary endpoint for the registrational study of EB613 in post-menopausal osteoporosis patients. The single pivotal Phase 3 clinical trial includes a 24-month placebo-controlled duration with change in Total Hip BMD assessed as the primary endpoint. The 2:1 randomization and planned 400 patients exposed to EB613 are expected to be sufficient to support both the safety and efficacy assessments for the NDA. Furthermore, the FDA agreed with Entera's proposed enrollment of post-menopausal women with osteoporosis based on a BMD T-score of less than or equal to-2.5 to -3.0 and no major fracture history. This patient population is consistent with that studied during Entera's Phase 2 6-month dose ranging study of EB613, which met all primary and key secondary endpoints of biochemistry and BMD. Finally, Entera intends to submit relative PK data comparing its oral tablet form of teriparatide, EB613 versus the subcutaneous injection of teriparatide, Forteo to support the 505(b)(2) pathway.

06:52 EDT ArcelorMittal down 4.8% in pre-market at $20.70 after UBS downgrade to Neutral

06:46 EDT Stantec awarded $20M contract for Gross Reservoir expansion project - Stantec has been named Engineer of Record providing engineering support during construction for the second phase of the Gross Reservoir Expansion Project in Boulder County, Colorado. The $531M project will raise the height of the existing concrete curved gravity dam by 131 feet, increasing the reservoir's capacity to approximately 119,000 total acre-feet and making it the tallest dam in Colorado. Stantec's $20M construction phase contract will include owner support, contractor quality reviews, and regulatory compliance.

06:40 EDT ViaSat, Inmarsat provides update on planned transaction - Viasat and Inmarsat remain committed to working with the UK's Competition and Markets Authority, or CMA, to demonstrate how their planned transaction will benefit airline, passenger, and enterprise users of In-Flight Connectivity, or IFC, in aviation businesses. As their engagement with the CMA progresses, the companies will determine and communicate any updated expectations for closing. The proposed transaction has already secured several key regulatory approvals, most recently with the UK Government's clearance of the proposed transaction under the National Security and Investment Act, and over the summer from the Committee on Foreign Investment in the United States.

06:05 EDT Bowlero to acquire four bowling centers - Bowlero announced that it has entered into definitive agreements to acquire four bowling centers - Strikes Unlimited in California, and Super Bowl Family Entertainment Center, Sabre Lanes and JB's on 41 located in Wisconsin. The completion of the four acquisitions is expected by the end of October.

06:02 EDT Venator Materials saw meaningful decline in sales volume for TiO2 products - Venator Materials provided a third quarter business update. Simon Turner, president and CEO of Venator, commented, "During the third quarter we saw a meaningful decline in sales volume for our TiO2 products in the European and Asian regions. We expect to report third quarter TiO2 sales volumes to be approximately 25% lower than in the second quarter. With limited outlook visibility and persistently high European energy costs, we have reduced production at our Uerdingen, Germany, facility to minimal levels and are reducing production at our Duisburg facility in Germany as well. We are also implementing other cost mitigation actions across the business. Demand for products from our Performance Additives businesses has been more resilient and the segment continues to perform reasonably well."

05:35 EDT Equinix announces plans for $74M data center in Jakarta - Equinix announced its expansion to Indonesia with plans for an approximately $74M International Business Exchange data center in the heart of Jakarta. Through this expansion, Equinix will enable Indonesian businesses, as well as multinationals with a presence in Indonesia, to leverage its trusted platform to bring together and interconnect the foundational infrastructure to power their businesses. The eight-story facility is scheduled to open by the second half of 2024, expected to provide more than 1,600 cabinets and more than 5,300 square meters of colocation space when fully built. In Asia-Pacific, Equinix announced an initial investment of over $86M to build Equinix's third IBX data center in Mumbai and an investment of over $64M for its first IBX data center in Chennai.

05:24 EDT UMC reports September sales of NT$25.21M, up 34.5%

05:19 EDT Hyatt enters exclusive collaboration with Lindner Hotels - Hyatt announced that a Hyatt affiliate has entered into an exclusive collaboration agreement with Lindner Hotels, a family-run German hospitality business, focused on hotel developments, management and investments. It is expected that more than 30 hotels across seven European countries will join the Hyatt brand portfolio and will be integrated into the World of Hyatt loyalty program in the near future. The majority of the properties are slated to transition to the JdV by Hyatt brand, a collection of independent hotels. Lindner Hotels AG, a German family-owned hospitality company founded in 1973 by architect Otto Lindner, operates a variety of properties under the Lindner Hotels & Resorts and the me and all hotels brands in key cities across Germany and in Central and Eastern Europe. The agreement will expand Hyatt's brand footprint to 15 new markets and extend distribution in key destinations such as Dusseldorf, Frankfurt, and Hamburg. The Lindner portfolio will further increase Hyatt's lifestyle footprint with the addition of an estimated 5,500 rooms, significantly growing Hyatt's footprint in Germany. As part of this agreement, Lindner Hotels will have access to data-driven support around brand health, guest experiences and revenue optimization from Hyatt's Global Franchise and Owner Relations Group.

05:11 EDT Extreme Networks, Verizon to deploy wireless connectivity solutions at Anfield - Extreme Networks (EXTR) announced it has selected Verizon Business (VZ), a division of Verizon, as its partner to deploy wireless connectivity solutions at Liverpool FC's Anfield Stadium as part of Extreme's partnership with the Premier League club. The deployment, expected to begin later this year, includes Extreme Wi-Fi 6 access points which will provide the Wi-Fi connectivity required to power memorable, engaging fan-centric experiences such as mobile ticketing, cash-free concessions, shopping at the team store, video streaming and new digital immersive experiences. As part of the partnership, Liverpool FC will also leverage ExtremeAnalytics to get real-time insights into data including fan foot traffic, app usage across the stadium and popular concessions. ExtremeCloud will enable the club to monitor and control Wi-Fi capacity and efficiency, device configuration and analytics and provide a single view into the health, performance and security of the network.

05:05 EDT IBM to invest $20B across Hudson Valley region in New York over next 10 years - President Joseph Biden and IBM chairman and CEO Arvind Krishna will tour IBM's Poughkeepsie, New York site. During the visit, IBM will announce a plan to invest $20B across the Hudson Valley region over the next 10 years. The goal of the investments, which will be strengthened by close collaboration with New York State, is to expand the technology ecosystem in New York to unlock new discoveries and opportunities in semiconductors, computers, hybrid cloud, artificial intelligence and quantum computers.