Stockwinners Market Radar for September 14, 2022 - Earnings, Upgrades downgrades, option trades, Best Stock Advisory Service |
TME | Hot Stocks19:43 EDT Tencent Music announces proposed secondary listing on Hong Kong stock exchange - Tencent Music announced the proposed secondary listing of its Class A ordinary shares, par value US$0.000083 per share by way of introduction on the Main Board of The Stock Exchange of Hong Kong Limited. The Company's American Depositary Shares, each representing two Shares, will continue to be primarily listed and traded on the New York Stock Exchange.
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MNOV | Hot Stocks19:13 EDT MediciNova receives issue notification from U.S. PTC for new MN-166 patent - MediciNova "announced that it has received an Issue Notification from the U.S. Patent and Trademark Office for a new patent which covers MN-166, ibudilast, for the treatment of glioblastoma. This new patent is expected to expire no earlier than February 2039. The allowed claims cover a method of treating a patient diagnosed with glioblastoma or recurrent glioblastoma, wherein the patient expresses unmethylated MGMT, using MN-166 in combination with one or more other therapeutic agents including temozolomide, carmustine, bevacizumab, procarbazine, hydroxyurea, irinotecan, lomustine, nimotuzumab, sirolimus, mipsagargin, cabozantinib, onartuzumab, patupilone, and recombinant oncolytic poliovirus (PVS-RIPO). The allowed claims cover a wide range of doses of MN-166 as well as the other therapeutic agents. The allowed claims also cover different types of glioblastoma including classical glioblastoma, proneural glioblastoma, mesenchymal glioblastoma, and neural glioblastoma."
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TNET | Hot Stocks18:39 EDT TriNet announces launch of Enrich Learn - TriNet announced at TriNet PeopleForce the launch of Enrich Learn, the newest benefit product offering from its recently launched Enrich product line. Enrich Learn will offer tax-optimized reimbursements for expenses by SMB employees to advance their education. Like the other Enrich products, Enrich Learn is a turn-key solution for benefits sponsored by the SMB. Enrich Learn will be available to all of TriNet's 23,000 SMB customers starting next month. The previously announced product releases include Enrich Access, which allows for TriNet customers to offer tax-optimized travel reimbursements for medical care, and Enrich Adopt, which offers reimbursements for expenses incurred during the adoption process. "Our Enrich product line is designed to allow SMBs to make choices in benefit offerings that are right for their company. SMB leaders recognize that the benefits they offer speak to the culture that they are building," said Burton M. Goldfield, President and CEO of TriNet. "It's just one more way TriNet seeks to fulfill its mission to power the success of SMBs by supporting their growth and enabling their people."
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BSY | Hot Stocks18:31 EDT Bentley Systems CEO sells $6.2M in common stock - In a regulatory filing, Bentley Systems disclosed that its CEO Gregory Bentley sold 168.3K shares of common stock on September 12th in a total transaction size of $6.2M.
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NEXA | Hot Stocks17:48 EDT Nexa Resources appoints Jose Carlos del Valle as CFO - Nexa Resources has appointed Jose Carlos del Valle as Nexa's Senior VP of Finance and Group CFO, effective October 3rd. del Valle joins Nexa after spending nine years as CFO at Compania Minera Antamina. Before Antamina, he was the CFO of Volcan Compania Minera. Prior to that, he held various leadership positions at well-known companies, including McKinsey & Company, Standard Chartered Bank, and Wells Fargo Bank, among others.
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LOGI | Hot Stocks17:46 EDT Logitech shareholders approve dividend increase of 10% - Logitech "announced that during its annual general meeting the Company's shareholders approved a dividend of approximately CHF 0.96 per share - an increase of approximately 10% compared to FY21 dividend."
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PAAS | Hot Stocks17:42 EDT Pan American Silver reports increase to mineral resource estimate at La Colorada - Pan American Silver Corp. announced an updated mineral resource estimate for its 100% owned La Colorada Skarn deposit in Zacatecas, Mexico. The estimated indicated mineral resource totals 95.9M tonnes containing 94.4M ounces of silver, 2.7M tonnes of zinc and 1.2M tonnes of lead. In addition, the estimated inferred mineral resource now totals 147.8M tonnes containing 132.9M ounces of silver, 3.4M tonnes of zinc and 1.5M tonnes of lead. The updated mineral resource estimate is a significant increase relative to our previous mineral resource estimate released on August 4, 2020. The mineral resource estimate is based on a $45 per tonne unit cut-off value and an underground sub-level cave mining method followed by processing through a selective flotation beneficiation plant that generates zinc and lead concentrates. "Our exploration team has done a remarkable job of delineating a large resource with notable growth potential in only four years. Our confidence in the geology has also improved, resulting in a large portion of the deposit now being classified as indicated resources," said Christopher Emerson, Pan American's Vice President Business Development and Geology. "Notably, the high-grade intersects we announced on July 21, 2022 are not included in today's mineral resource estimate, and the deposit remains open in nearly all directions for further resource expansion."
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APA | Hot Stocks17:22 EDT APA Corp. board approves additional buyback of 40M shares of common stock
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APA | Hot Stocks17:20 EDT APA Corp. doubles quarterly dividend to 25c per share - The next quarterly dividend on common shares is payable November 22 to stockholders of record on October 21.
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BAH | Hot Stocks17:10 EDT Booz Allen CFO Howell to retire, Calderone named next CFO - Booz Allen Hamilton announced that Chief Financial Officer Lloyd W. Howell, Jr. will be retiring December 31, 2022, and Matthew A. Calderone, who currently serves as the firm's Chief Strategy Officer, will succeed him as CFO effective October 1, 2022. Howell will continue in his role of Executive Vice President to assist with the transition in the coming months. "Lloyd has made tremendous contributions to Booz Allen during his 34 year-tenure, culminating most recently in his role as CFO," said Horacio Rozanski, Booz Allen's President and Chief Executive Officer. "Lloyd has helped to guide Booz Allen through a period of tremendous growth and transformation that delivered significant growth in shareholder value and strong returns. He has helped build a world-class financial team and contributed to making Booz Allen the industry growth leader we are today. He leaves our firm well-positioned to scale and grow even faster in the future."
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NCLH | Hot Stocks17:03 EDT Norwegian Cruise Line exec Montague sells 62,758 common shares - In a regulatory filing, Norwegian Cruise Line president and CEO of RSSC Jason Montague disclosed the sale of 62,758 common shares of the company on September 12 at a price of $14.68 per share.
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GVA | Hot Stocks17:01 EDT Granite secures $17M Duncan Creek Diversion Dam contract - Granite "announced that it has been awarded an approximately $17M construction contract by the Placer County Water Agency for updates and improvements at the Duncan Creek Diversion Dam near Foresthill, California. The dam is one of the hundreds of older, small dams in Northern California's Sierra Nevada Mountains. Many of them will require major modifications in the near future in order to bring them up to modern standards. Through the improvement project, the Duncan Creek dam will be brought up to current standards as required by the California Department of Water Resources Division of Safety of Dams, while improving fish passage and allowing for more efficient operation of the facility. The award is anticipated to be included in Granite's third quarter cap."
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IDYA | Hot Stocks16:48 EDT Ideaya Biosciences drops 10% to $11.24 after announcing $80M stock offering
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SJM | Hot Stocks16:47 EDT J.M. Smucker names Amy Held chief transformation officer - J.M. Smucker announced the formation of a transformation office, which will be overseen by Amy Held in the newly created role of chief transformation officer. Held previously served as the company's chief strategy and international officer. In corresponding decisions, the company announced it will undertake a rigorous search to fill the chief strategy officer role. Held will maintain oversight of strategy while the company recruits to fill the position. Additionally, Tim Wayne, who has taken on the expanded role of VP, international and Away From Home, will now oversee the international business. The company plans to share further details on its transformation office at its upcoming investor day on December 14.
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CMP | Hot Stocks16:47 EDT Compass Minerals achieves 'several key milestones' at Great Salt Lake - The company "announced the achievement of several key milestones and provided strategic updates regarding development of its previously identified, approximately 2.4 mMT lithium carbonate equivalent resource on the Great Salt Lake. Phase one of development is expected to be located on the east side of the Great Salt Lake where a significant portion of the company's existing infrastructure is located. Highlights include: Selected EnergySource Minerals as DLE technology provider following three years of extensive testing of multiple DLE technologies; Low-cost, long-life brownfield project at Ogden, Utah solar evaporation facility, leveraging robust existing infrastructure; Targeting phase-one production of approximately 11 kMT LCE annually; Estimated phase-one development capital of $262M (-30% to +40%); Phase one expected to yield approximately $626 million to $985 million in after-tax NPV and an after-tax IRR between 28% and 36%."
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NWL | Hot Stocks16:36 EDT Newell Brands director Mather sells 50,000 common shares - In a regulatory filing, Newell Brands director Courtney Mather disclosed the sale of 50,000 common shares of the company on September 12 at a price of $18.17 per share.
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ELOX | Hot Stocks16:35 EDT Eloxx Pharmaceuticals trading resumes
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HST | Hot Stocks16:33 EDT Host Hotels recommends shareholders reject MacKenzie Capital mini tender offer - Host Hotels has learned that MacKenzie Capital made an unsolicited "mini-tender" offer for up to 100,000 operating partnership units of Host Hotels & Resorts, L.P. at a price of $13.00 per OP Unit less cash distributions made by Host L.P. after July 15. This follows multiple earlier "mini-tender" offers by the Purchaser launched between 2016 and 2021. Neither the company nor Host L.P. are in any way associated with the MacKenzie Offer, and holders of OP Units are under no obligation to take any action with respect to the MacKenzie Offer. Mini-tender offers seek less than 5% of a company's outstanding equity. This allows the offering company to avoid many of the United States Securities and Exchange Commission disclosure and procedural requirements for tender offers. This guidance advises that mini-tender offers "have been increasingly used to catch investors off guard" and that investors "may end up selling their securities at below-market prices." The company said, "After careful evaluation of the MacKenzie offer, the company and Host L.P. recommend that the holders of OP Units reject this unsolicited offer. In making this recommendation, the Company primarily considered that the offer price in the MacKenzie offer is below the $17.88 per share closing stock price of the Company's common stock on September 13, 2022. Although there is no trading market for the OP Units themselves, at any time holders of OP Units may request that the Company redeem their OP Units and the Company will issue 1.021494 shares of the Company's common stock in exchange for each OP Unit, which shares may then be sold. Based on the closing price of the Company's common stock on September 13, 2022 of $17.88, an OP Unitholder would receive shares with a market value of approximately $18.26 compared to the cash MacKenzie Offer of $13.00. The Purchaser has made many similar unsolicited mini-tender offers for equity of other companies and multiple earlier unsolicited mini-tender offers to holders of Host L.P. units at a similar discount to current market value. Like its other offers, this offer puts individual investors at risk because they may not realize they are selling their OP Units at a discount. The Company urges investors to get current quotes for the Company's common stock for which their OP Units may be redeemed, consult their financial and tax advisors and exercise caution with respect to the MacKenzie Offer. The Company recommends that OP Unitholders who have not responded to the Purchaser's offer take no action."
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MVBF | Hot Stocks16:32 EDT MVB Financial to name Steven Crouse as CFO - In connection with the previously announced definitive merger agreement of MVB Financial and Integrated Financial Holdings, Steven Crouse will be appointed CFO of MVBF upon closing of the transaction. Crouse most recently served as Executive Vice President, CFO for Integrated Financial Holdings.
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PYPL | Hot Stocks16:26 EDT PayPal CFO Jorgensen taking leave of absence - According to a regulatory filing, on September 14, 2022, PayPal Holdings announced that Blake Jorgensen, Executive Vice President and Chief Financial Officer, is taking a leave of absence for health reasons. The Board of Directors has appointed Gabrielle Rabinovitch to serve as the company's acting Chief Financial Officer and perform the duties of the principal financial officer of the company, effective immediately. Rabinovitch joined the company in April 2016. She currently serves as the company's Senior Vice President, Capital Markets, Investor Relations and Treasurer. Previously, she served as the company's interim Chief Financial Officer from May 2022 to August 2022, and as Senior Vice President, Corporate Finance and Investor Relations from September 2021 to September 2022. Prior to that, Rabinovitch served as the company's Vice President, Investor Relations.
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RGA | Hot Stocks16:23 EDT Reinsurance Group board chair Eason to retire on December 31 - Reinsurance Group of America announced the upcoming retirement of Board Chair J. Cliff Eason. Eason will retire from his position on December 31, 2022, and current Board Member Stephen T. O'Hearn will assume the role of Chair on January 1, 2023. "On behalf of the entire organization, I want to thank Cliff for the remarkable leadership, outstanding stewardship, and unwavering encouragement he has provided during his nearly 30 years of service on the RGA Board," said Anna Manning, President and Chief Executive Officer, RGA. "Cliff is a leader of the highest integrity and we wish him the very best in his upcoming retirement."
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IRNT | Hot Stocks16:22 EDT IronNet co-CEO William Welch resigns - IronNet said that Co-CEO William Welch will resign as co-CEO and from the Board of Directors in light of the restructuring of the business, and indicated he will continue to support the company in the short term. Chris Murphy, Head of Sales Operations, will lead the sales team in the interim, reporting to GEN (Ret.) Keith Alexander. Cameron Pforr has been appointed as IronNet's new Chief Financial Officer (CFO), replacing current CFO James Gerber who will be departing the company to join a private cybersecurity company.
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IRNT | Hot Stocks16:21 EDT IronNet withdraws previously issued FY23 guidance - In light of the management transitions, further restructuring of the company, and the underperformance of the transactional business this quarter, the company is withdrawing its previously issued revenue and ARR guidance for fiscal 2023.
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FTI | Hot Stocks16:21 EDT TechnipFMC awarded subsea contract by TotalEnergies - TechnipFMC has been awarded a "significant" engineering, procurement, construction and installation contract by TotalEnergies for its Lapa North East field in the pre-salt Santos Basin offshore Brazil. TechnipFMC will reconfigure and install umbilicals and flexible pipe in a new configuration that will further secure the production of the field. For TechnipFMC, a "significant" contract is between $75M and $250M.
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DHR | Hot Stocks16:20 EDT Danaher to separate Environmental & Applied Solutions unit into public company - Danaher announced its intention to separate its Environmental & Applied Solutions segment to create an independent, publicly traded company. The new company will be comprised of Danaher's Water Quality and Product Identification businesses and will be referred to as "EAS" until it is named at a later date. The transaction is intended to be tax-free to Danaher shareholders and expected to be completed in the fourth quarter of 2023. Jennifer Honeycutt will become President and CEO of EAS upon completion of the transaction. Honeycutt joined Danaher in 1999 via the acquisition of Hach and she currently serves as a Danaher Executive Vice President with responsibility for the Environmental & Applied Solutions segment. Honeycutt has extensive mergers and acquisitions experience and brings a strong operational track record to EAS, having overseen accelerated business performance at several Danaher operating companies. EAS will have leading positions and outstanding brands in the areas of water quality and product identification. EAS will be comprised of Danaher's current Environmental & Applied Solutions segment operating companies including Hach, ChemTreat, Trojan, OTT, and McCrometer in Water Quality and Videojet, X-Rite Pantone, Esko and Linx in Product Identification. The segment generated revenue of approximately $4.7B in 2021 and has a global team of approximately 16,000 associates united by a common culture and operating system, with the Danaher Business System as its foundation. As a standalone entity EAS is expected to have an investment-grade credit rating.
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VTAQ | Hot Stocks16:20 EDT Ventoux CCM Acquisition Corp. holders approve business combination with Presto - Ventoux CCM Acquisition Corp., a special purpose acquisition company, announced that Ventoux's stockholders have approved its proposed merger with E La Carte, one of the largest labor automation technology providers in the hospitality industry, at a Special Meeting of its stockholders held on September 14, 2022. Approximately 99% of the votes cast at the Special Meeting, representing approximately 80% of Ventoux's outstanding shares of common stock entitled to vote at the Special Meeting, were cast in favor of the proposal to approve the Business Combination. The formal results of the Special Meeting will be included in a Current Report on Form 8-K to be filed by Ventoux with the Securities and Exchange Commission. The closing of the business combination is expected to take place on September 20, 2022. It is anticipated that the transaction will result in at least approximately $92.1 million in gross proceeds for the post-closing company, including proceeds from Ventoux's trust account and the previously announced committed private placement. Upon the closing of the Business Combination, the combined company (the "Company") will be renamed "Presto Automation Inc." and its common stock and warrants are expected to begin trading on the Nasdaq Stock Market beginning on September 21, 2022 under the ticker symbols "PRST" and "PRSTW" respectively.
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EXPE | Hot Stocks16:19 EDT Expedia names Julie Whalen CFO - Expedia announced that Julie Whalen will be Expedia Group's Executive Vice President and Chief Financial Officer, effective September 26, 2022. She succeeds Eric Hart, who will remain with the Company through October 1, 2022, to ensure a seamless transition. As Expedia Group's EVP and CFO, Ms. Whalen will lead the Company's global finance organization and financial activities including accounting, corporate development, financial reporting and analysis, internal audit, investor relations, real estate, tax, and treasury. "Julie is a highly respected financial executive with years of success as an operating leader. She comes with a background and commitment to understanding customers and driving long-term value. We are excited to bring Julie's energy and drive to our leadership team and look forward to the impact she can bring to our finance organization and across our entire enterprise," said Peter Kern, Vice Chairman and CEO, Expedia Group.
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ARNC | Hot Stocks16:18 EDT Arconic sees completing Extrusions segment review in Q3 - Arconic said that management expects to complete a business review of the Extrusions segment in the third quarter aimed at identifying alternatives to improve the financial performance of this segment in future periods. Such alternatives could include changes to the operations that may result in asset impairment charges. As of June 30, 2022, the aggregate carrying value of the Extrusions segment's properties, plants, and equipment, intangible assets, and operating lease right-of-use assets was approximately $230 million.
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VMEO | Hot Stocks16:17 EDT Vimeo reports August revenue up 9% - Reports August average revenue per user up 8%. Reports August subscribers up 1%.
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ARNC | Hot Stocks16:17 EDT Arconic sees Q3 adjusted EBITDA $135M-$150M - Third quarter 2022 Adjusted EBITDA is expected to be in the range of $135 million to $150 million. The third quarter results will be impacted by production outages and other operational challenges in Tennessee and Davenport that have reduced production from planned operating rates. Additionally, hyperinflationary energy costs are driving increased cost pressures and declining demand in Europe, which are expected to have an increasingly negative impact on third and fourth quarter results.
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DHR | Hot Stocks16:16 EDT Danaher to separate Environmental & Applied Solutionsunit into public company - Danaher announced its intention to separate its Environmental & Applied Solutions segment to create an independent, publicly traded company. The new company will be comprised of Danaher's Water Quality and Product Identification businesses and will be referred to as "EAS" until it is named at a later date. The transaction is intended to be tax-free to Danaher shareholders and expected to be completed in the fourth quarter of 2023. Jennifer Honeycutt will become President and CEO of EAS upon completion of the transaction. Honeycutt joined Danaher in 1999 via the acquisition of Hach and she currently serves as a Danaher Executive Vice President with responsibility for the Environmental & Applied Solutions segment. Honeycutt has extensive mergers and acquisitions experience and brings a strong operational track record to EAS, having overseen accelerated business performance at several Danaher operating companies.
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ADM PEP | Hot Stocks16:16 EDT PepsiCo, ADM form pact to support regenerative agriculture practices - ADM (ADM) and PepsiCo (PEP) announced a 7.5-year strategic commercial agreement to closely collaborate on projects that aim to significantly expand regenerative agriculture across their shared North American supply chains. This strategic partnership is expected to reach up to 2M acres by 2030, and represents a trailblazing effort by two global companies that share ambitious carbon reduction goals. The companies' capabilities span the food and agriculture value chains, creating a unique, large-scale platform to support farmers' transition to regenerative agriculture, while building their resilience to climate change. The long-term agreement will initially enroll corn, soy and wheat farmers across Kansas, Minnesota, Iowa, Illinois, Indiana and Nebraska, with the opportunity for future expansion, to increase visibility across the value chain and integrate a range of multi-year farmer-first regenerative agriculture initiatives, including cover crops, reduced tillage, nutrient management, diverse rotations, and responsible pesticide use. The companies plan to share resources and collaborate to create value throughout the supply chain by providing participants with technical and financial assistance, offering access to peer regenerative farming networks, hosting educational field days, and tracking results using trusted, third-party measurement systems. "Building a better food system is essential to the future health of the earth and all of us," said Jim Andrew, Chief Sustainability Officer, PepsiCo. "At its core, PepsiCo is an agricultural company, working to spread regenerative agriculture practices that restore the earth and reduce carbon emissions to 7 million acres by 2030. This partnership with ADM marks a sea change in how PepsiCo engages with strategic partners and is expected to help us reach almost one-third of that goal. By enabling greater collaboration through strategic partnerships like this one, we can strengthen the livelihoods and resilience of the farmers we work with, while building a more sustainable future together."
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NETI | Hot Stocks16:13 EDT Eneti authorizes $50M share repurchase program - Eneti announced that on September 13, its Board of Directors authorized the repurchase of up to $50M of the Company's common stock in open market purchases, privately negotiated transactions or otherwise in accordance with applicable U.S. federal securities laws, including sales pursuant to Rule 10b5-1 trading plans and under Rule 10b-18 of the Securities Exchange Act of 1934.
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PCH CTT | Hot Stocks16:12 EDT PotlatchDeltic, CatchMark complete merger - PotlatchDeltic (PCH) "announced the successful completion of the previously announced merger of CatchMark Timber Trust (CTT) in an all-stock transaction, creating a leading integrated timber REIT. All closing conditions have been met. PotlatchDeltic also announced that James DeCosmo, who served on CatchMark's board since 2020, became a PotlatchDeltic director effective with the merger close. PotlatchDeltic's board now consists of 10 directors. In accordance with the terms of the merger agreement, each outstanding share of CatchMark common stock immediately prior to the merger converted to the right to receive 0.23 shares of PotlatchDeltic common stock. In total, approximately 11.5M shares of PotlatchDeltic common stock will be issued to CatchMark shareholders, representing approximately 14% of total shares outstanding. In conjunction with the merger, PotlatchDeltic refinanced $277.5M of CatchMark's debt and repaid another $22.5M of such debt."
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AATC | Hot Stocks16:09 EDT Autoscope Technologies subsidiary partners with Butterfly Junction Technologies - Image Sensing Systems, a wholly-owned subsidiary of Autoscope Technologies, announced that it has partnered with Butterfly Junction Technologies. This partnership will elevate Image Sensing Systems, or ISS, above-ground RTMS radar technology for the Intelligent Transportation Systems, or ITS, market. Butterfly Junction Technologies has a traffic management software suite called BumbleDrive that provides the transportation industry with a platform of solutions. The platform combined with an RTMS Echo radar sensor allows transportation professionals to visually access their per-vehicle and interval data, giving them the insights to understand better what is happening on their roadways.
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KCAC | Hot Stocks16:08 EDT Kensington Capital Acquisition, Amprius Technologies complete merger - Amprius Technologies announced that it has completed its business combination with Kensington Capital Acquisition Corp. IV . The Business Combination was approved by Kensington shareholders in a special meeting held on September 13, and formally closed September 14. On September 15, Amprius' common stock will begin trading on the NYSE under the ticker symbol "AMPX" and Amprius' public warrants will trade under the ticker symbol "AMPX.W."
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ELOX | Hot Stocks16:07 EDT Eloxx Pharmaceuticals announces ELX-02 trial did not meet efficacy endpoints - Eloxx Pharmaceuticals announced results from the Phase 2 clinical trial of ELX-02 in combination with ivacaftor in Class 1 cystic fibrosis, or CF, patients with at least one nonsense mutation. The combination trial of ELX-02 with ivacaftor was well tolerated but did not achieve statistical significance for efficacy endpoints, including changes from baseline in sweat chloride concentration, or SCC, and percent forced expiratory volume, or FEV1. The Phase 2 combination clinical trial of ELX-02 was designed to evaluate safety and assess biological activity in G542X nonsense mutation Class 1 CF patients as monotherapy and in combination with ivacaftor. The trial included a 1-week monotherapy period followed by a four week combination period. Topline results are summarized below: ELX-02 was generally well tolerated in the trial, with no treatment-related serious adverse events noted. Overall, the study did not achieve statistical significance for efficacy endpoints in the Phase 2 study in Class 1 CF for efficacy endpoints, including changes from baseline in SCC and FEV1. No incremental improvement was observed with ivacaftor combination. Evidence of activity for ELX-02 was observed, as patients with higher baseline sweat chloride levels demonstrated increased responses as indicated by SCC. Trial results were potentially confounded by high variability in sweat chloride and lung function measurement. Eloxx believes this variability could have been caused by very low drug exposures in the lung. Steady state lung drug levels in patients from this trial were on average 20%, or 2muM, of the lowest levels at which drug activity has previously been seen in preclinical testing. Lung drug exposure with inhaled delivery of ELX-02 expected to be at least 50-fold greater than with subcutaneous delivery.
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VLD | Hot Stocks16:07 EDT Kevton Technologies acquires seven Velo3D printers - Velo3D "announced Kevton Technologies, a subsidiary of Houston-based contract manufacturer Kevton Industries, has acquired seven Sapphire printers to provide its customers with high-quality, additively manufactured parts. The purchase is one of the largest ever with Velo3D from a contract manufacturer and will make Kevton Technologies one of the top suppliers of additively manufactured parts relying on Velo3D's laser powder bed fusion technology. The first two Sapphire printers are scheduled to begin producing parts for customers in Q1, 2023 in Kevton's Houston, Texas facility."
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BCRX | Hot Stocks16:06 EDT BioCryst appoints Dr. Ryan Arnold CMO, Dr. Sheridan as development chief - BioCryst Pharmaceuticals announced that Dr. Bill Sheridan will become chief development officer and will focus on advancing the company's significant pipeline of development candidates. Dr. Ryan Arnold has been appointed as the company's new chief medical officer.
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LAUR | Hot Stocks16:06 EDT Laureate Education announces special cash distribution of 83c per share - Laureate Education announced that its board of directors approved, pursuant to the previously announced adoption of a plan of partial liquidation related to the distribution of net proceeds from the company's sale of Walden e-Learning, the payment of a special cash distribution equal to 83c per each share of the company's common stock, par value $0.004 per share, to each holder of record on September 28. The Distribution is scheduled to be paid on October 12. Based on the current number of shares outstanding, the aggregate amount of the Distribution is expected to be approximately $137M. The proceeds being distributed are attributable to the release of $71.7M of escrowed funds from the Sale plus remaining net proceeds that had yet to be distributed. This is anticipated to be the final distribution pursuant to the Plan.
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ELOX | Hot Stocks16:06 EDT Eloxx Pharmaceuticals trading halted, news pending
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QGEN | Hot Stocks16:06 EDT Qiagen, Neuron23 partner over LRRK2 inhibitor companion diagnostic - Qiagen and Neuron23 announced the signing of an agreement to develop a companion diagnostic for Neuron23's brain penetrant leucine-rich repeat kinase inhibitor for Parkinson's disease. Under the new Master Collaboration Agreement, QIAGEN will develop and validate a clinical trial assay that will detect a combination of biomarkers discovered by Neuron23 that together predict the responsiveness of Parkinson's disease to a LRRK2 inhibitor. The partnership will support the clinical development of Neuron23's drug candidate that is currently in the late stages of preclinical development. Subject to further clinical development, the agreement also covers options for the future development of additional companion diagnostics. Neuron23 joins a group of more than 25 leading pharmaceutical and biotechnology companies who have reached master collaboration agreements with QIAGEN to develop and commercialize companion diagnostic tests for their drug candidates - a deep pipeline of potential future products to advance precision medicine for the benefit of patients around the world.
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WSM EXPE | Hot Stocks16:06 EDT Williams-Sonoma names Jeff Howie as new CFO - Williams-Sonoma (WSM) announced the appointment of Jeff Howie to CFO. During his 20-year tenure at Williams-Sonoma, Inc., Howie has held key executive leadership roles for the Williams Sonoma, Pottery Barn, Pottery Barn Kids and Pottery Barn Teen brands. Most recently, Howie has served as Williams-Sonoma, Inc.'s Executive Vice President, Chief Administrative Officer overseeing Finance, Inventory, and Outlets across the Pottery Barn brands, as well as Real Estate, Store Development, Corporate Facilities, and Business to Business for all of Williams-Sonoma, Inc. Former Chief Financial Officer of Williams-Sonoma, Inc., Julie Whalen, has accepted the role of Chief Financial Officer of Expedia Group (EXPE).
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MOND | Hot Stocks16:06 EDT Mondee Holdings Inc trading resumes
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MOND | Hot Stocks16:05 EDT Mondee Holdings Inc trading halted, volatility trading pause
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QGEN | Hot Stocks16:03 EDT Qiagen, Neuron23 announce collaboration on Parkinson's disease - Neuron23 and Qiagen announced a collaboration to develop a companion diagnostic for Neuron23's LRRK2 inhibitor for Parkinson's disease. Under the Master Collaboration Agreement, Qiagen will develop and validate a clinical trial assay that will detect a combination of biomarkers discovered by Neuron23 that together predict the responsiveness of Parkinson's disease patients to a LRRK2 inhibitor. The partnership will support the clinical development of Neuron23's drug candidate that is currently in the late stages of preclinical development. Subject to further clinical development, the agreement also covers options for the future development of additional companion diagnostics. The assay for this collaboration will be integrated into a next-generation sequencing workflow that leverages Qiagen's Sample to Insight capabilities. Parallel development of the diagnostic assay and the therapeutic will allow the companies to submit the application to the U.S. FDA for premarket approval of the NGS companion diagnostic test in tandem with the new drug application for Neuron23's LRRK2 inhibitor.
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KYMR | Hot Stocks14:57 EDT Kymera Therapeutics treatment of CTCL granted orphan designation - Kymera Therapeutics' treatment of Cutaneous T-Cell Lymphoma, or CTCL, was granted orphan designation by the FDA, according to a post to the agency's website. Reference Link
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SQ | Hot Stocks14:45 EDT Block says can address additional demographics with Cash App - Says Cash App has grown to 47M monthly active users and sees opportunities to address additional demographics with Cash App over time. Block executives are presenting at the Goldman Sachs Communacopia & Technology Conference.
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QH | Hot Stocks14:27 EDT Quhuo added to provisional list of issuers identified under HFCAA - Quhuo Limited was provisionally identified under the HFCAA, or Holding Foreign Companies Accountable Act, on September 14 according to a post to the SEC website. "Issuers provisionally identified will have 15 business days to contact Commission staff if they believe they have been incorrectly identified, and should include evidentiary support with their correspondence. Issuers are not subject to the requirements under the HFCAA until they have been conclusively identified," the SEC HFCAA site noted. Among other things, the HFCAA requires the SEC to identify public companies that have retained a registered public accounting firm to issue an audit report where the firm has a branch or office that is located in a foreign jurisdiction, and the Public Company Accounting Oversight Board has determined that it is unable to inspect or investigate completely because of a position taken by an authority in the foreign jurisdiction. Reference Link
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AMZN | Hot Stocks14:15 EDT California AG sues Amazon over 'artificially high prices' - California Attorney General Rob Bonta announced his office had filed a lawsuit in San Francisco Superior Court against Amazon.com, alleging the company's contracts with third-party sellers and wholesalers lead to "artificially high" prices, reduce competition and violate the state's antitrust and unfair competition laws. The suit seeks to block Amazon from continuing those policies and to appoint a monitor to ensure compliance, according to a copy viewed by The Wall Street Journal. It also seeks unspecified damages for harm to the state economy and $2,500 for each violation of the state's civil and professional code proved at trial. "Amazon coerces merchants into agreements that keep prices artificially high, knowing full-well that they can't afford to say no," Bonta said. "We won't let Amazon bend the market to its will at the expense of consumers and the economy," he added.
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PARA | Hot Stocks14:02 EDT Paramount announces launch of Paramount+ in Italy - Paramount+, the streaming service from Paramount, launches tomorrow, September 15, in Italy "with more than 8,000 hours of entertainment," the company announced.
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CNI... | Hot Stocks13:55 EDT North American rail traffic up 1.5% for the week ending September 10 - The Association of American Railroads or AAR reported U.S. rail traffic for the week ending September 10. For this week, total U.S. weekly rail traffic was 464,261 carloads and intermodal units, down 0.9% compared with the same week last year. Total carloads for the week ending September 10 were 223,384 carloads, down 0.2% compared with the same week in 2021, while U.S. weekly intermodal volume was 240,877 containers and trailers, down 1.7% compared to 2021.Five of the 10 carload commodity groups posted an increase compared with the same week in 2021. They included motor vehicles and parts, up 3,251 carloads, to 13,373; grain, up 1,495 carloads, to 18,214; and farm products excl. grain, and food, up 720 carloads, to 15,695. Commodity groups that posted decreases compared with the same week in 2021 included metallic ores and metals, down 2,451 carloads, to 19,937; coal, down 2,432 carloads, to 67,492; and miscellaneous carloads, down 1,595 carloads, to 8,265. North American rail volume for the week ending September 10 on 12 reporting U.S., Canadian and Mexican railroads totaled 321,989 carloads, up 2% compared with the same week last year, and 323,856 intermodal units, up 1% compared with last year. Total combined weekly rail traffic in North America was 645,845 carloads and intermodal units, up 1.5%. North American rail volume for the first 36 weeks of 2022 was 24,341,405 carloads and intermodal units, down 2.4 percent compared with 2021. Publicly traded companies in the space include CSX (CSX), Canadian National (CNI), Canadian Pacific (CP), Kansas City Southern (KSU), Norfolk Southern (NSC), Union Pacific (UNP), Trinity Industries (TRN), Greenbrier (GBX), FreightCar America (RAIL) and Wabtec (WAB). Reference Link
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MSFT | Hot Stocks13:52 EDT Microsoft testing fullscreen widgets board for Windows 11 - Microsoft said in a blog post that it is releasing Windows 11 Insider Preview Build 25201 to the Dev Channel for Windows Insiders. "We are beginning to rollout expanded view for Widgets," the company said. "We're beginning the roll out to a small set of Insiders in the Dev Channel first so not everyone will see it right away. We are also beginning to roll out an update to the Game Pass widget that supports signing in with your Xbox profile and shows your recently played games from the Game Pass library." Reference Link
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MCD | Hot Stocks13:47 EDT McDonald's to open innovation lab at global headquarters - McDonald's Corporation is announcing the establishment of a new facility, Speedee Labs, which it said "will be focused on driving the customer experience and supporting restaurant teams through innovation," at its global headquarters located at 110 N. Carpenter Street in Chicago's West Loop neighborhood. McDonald's plans to relocate all jobs from its Innovation Center in Romeoville to MHQ's Speedee Labs, adding to its Cook County workforce, the company stated. Manu Steijaert, McDonald's Executive Vice President and Chief Customer Officer, added: "Just as the creation of McDonald's Customer Experience team brought key aspects of our business strategy together, the creation of Speedee Labs will enable more of our customers, restaurant teams, markets and global teams to contribute to our innovation, while driving growth and creating more seamless and memorable McDonald's experiences."
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UAL | Hot Stocks13:41 EDT United Airlines, Emirates announce commercial agreement - United Airlines and Emirates announced what they called "a historic commercial agreement" that will enhance each airline's network and give their customers easier access to hundreds of destinations. "United will launch a new direct flight between Newark/New York and Dubai starting in March 2023 - from there, customers can travel on Emirates or its sister airline flydubai to more than 100 different cities. Tickets for United's new Dubai flight are now on sale. Starting in November, Emirates customers flying into three of the nation's biggest business hubs - Chicago, San Francisco and Houston - will have access to nearly 200 U.S. cities in the United network - most of which only require a one-stop connection. At eight other U.S. airports served by Emirates - Boston, Dallas, LA, Miami, JFK, Orlando, Seattle and Washington DC - both airlines will have an interline arrangement in place," the companies announced.
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VZ | Hot Stocks13:02 EDT Verizon drops 1% to $41.33 after Goldman Sachs conference presentation
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VZ | Hot Stocks13:01 EDT Verizon CEO says price increase was 'right decision'
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NJR | Hot Stocks13:01 EDT New Jersey Resources raises quarterly dividend by 7.6% to 39c per share - The board of directors of New Jersey Resources unanimously approved a 7.6% increase in the quarterly dividend rate to 39c per share from 36.25c per share, the company announced. The new quarterly rate will be effective with the dividend payable October 3 to shareowners of record on September 26.
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VZ | Hot Stocks13:01 EDT Verizon CEO: Debt reduction is higher priority than buybacks right now
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VZ | Hot Stocks13:00 EDT Verizon sees decline in wireless subscribers in Q3 - Comments taken from the Goldman Sachs Communacopia + Technology Conference.
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SKIN | Hot Stocks12:51 EDT Beauty Health's Hydrafacial announces partnership with Organicell - The Beauty Health Company, home to flagship brand Hydrafacial, nnounced a collaboration with biotech company Organicell to co-create a first-to-market exosome booster that will address signs of aging and inflammation in the skin. The booster will leverage novel exosome technology based on regenerative medical therapies and, once developed, will be available as a customized treatment addition for Hydrafacial, the companies said in a statement. "We are excited to begin development with Organicell to co-create a potentially skin-changing Hydrafacial booster based on their breakthrough exosome technology," said BeautyHealth President and CEO Andrew Stanleick.
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MSFT... | Hot Stocks12:50 EDT EA says 'The Sims 4' base game will be free-to-play starting October 18 - Electronic Arts (EA) said that, starting October 18, 2022, "The Sims 4" base game will be available to all new players to download for free on PC via EA app or Origin, Mac via Origin, Steam, PlayStation 5 (SONY), PlayStation 4, Xbox Series X S (MSFT) and Xbox One systems. "With The Sims 4 going free to play, our team is more dedicated than ever to developing new and meaningful The Sims 4 experiences for our players and we will continue to develop and release packs, kits and Sims Delivery Express drops into the foreseeable future," the company said. "We'll be sharing more about what's in the works during a special-edition stream, Behind The Sims Summit on October 18, 2022 at 10 am PDT via The Sims YouTube and Twitch channels, also available on demand!" The Fly notes that "The Sims 4" first launched in 2014. Reference Link
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META AMZN | Hot Stocks12:43 EDT Amazon says tools can help sellers reach more shoppers on Facebook, Instagram - "Co-branded Buy with Prime social media ads, which are funded and managed by Amazon, help participating Buy with Prime sellers reach shoppers on Facebook and Instagram and drive traffic to products on their DTC sites. Potential customers see ads from Amazon's Buy with Prime page on Facebook and Instagram that feature specific sellers. When the shopper clicks on that ad, they're taken to a product detail page on the seller's DTC site where they can purchase directly from the seller using Buy with Prime. Co-branded social media ads are now available in an invitation-only beta," Amazon announced today at Accelerate, the company's annual seller conference.
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AMZN | Hot Stocks12:41 EDT Amazon announces new marketing solutions for DTC ecommerce sellers - Today at Accelerate, Amazon's annual seller conference, Amazon announced new marketing solutions that it said "enable direct-to-consumer ecommerce sellers to reach engaged Amazon shoppers and help drive sales on their own sites." Amazon is piloting the solutions as part of Buy with Prime, a new program that enables sellers to offer Prime shopping benefits to shoppers off Amazon, the company reported. "Direct-to-consumer online sellers struggle with two key pain-points: driving traffic and converting shoppers. With the launch of Buy with Prime, sellers have begun to increase conversion by offering shopping benefits that millions of Prime members love and trust-including fast, free delivery and a seamless checkout experience. Now, we're taking the next step by piloting marketing solutions to help Buy with Prime sellers attract more engaged shoppers to their sites," said Peter Larsen, Amazon's vice president of Buy with Prime. "Together, Sponsored Brands ads and the new Buy with Prime stores pages help Buy with Prime sellers reach relevant shoppers on Amazon and direct them to their own DTC sites. Both solutions are now available in an invitation-only beta," the company added.
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UNP... | Hot Stocks12:18 EDT Railroad union says 4,900 members voted to reject labor agreement - Approximately 4,900 members of the International Association of Machinists and Aerospace Workers District 19 have voted to reject the tentative agreement with the National Carriers' Conference Committee, the union announced. "The Tentative Agreement has been rejected and the strike authorization vote was approved by IAM District 19 members. Out of respect for other unions in the ratification process, an extension has been agreed to until Sept. 29, 2022 at 12 p.m. ET. This extension will allow us to continue to negotiate changes with the NCCC in the hopes of achieving an agreement our membership would ratify," it added. Publicly traded companies in the railroad space include CSX (CSX), Canadian National (CNI), Canadian Pacific (CP), Kansas City Southern (KSU), Norfolk Southern (NSC) and Union Pacific (UNP).
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PXXLF | Hot Stocks12:01 EDT Poxel Autosomal Dominant Polycystic Kidney Disease treatment gets orphan status - A potential treatment of Autosomal Dominant Polycystic Kidney Disease being developed by Poxel S.A. has been granted FDA orphan designation, according to a post to the agency website. Reference Link
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CXM | Hot Stocks12:00 EDT Sprinklr falls -9.2% - Sprinklr is down -9.2%, or -$1.15 to $11.34.
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AA | Hot Stocks12:00 EDT Alcoa falls -9.3% - Alcoa is down -9.3%, or -$4.67 to $45.62.
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SST | Hot Stocks12:00 EDT System1 falls -13.3% - System1 is down -13.3%, or -$1.30 to $8.50.
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NC | Hot Stocks12:00 EDT Nacco Industries rises 14.5% - Nacco Industries is up 14.5%, or $6.40 to $50.45.
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QBTS | Hot Stocks12:00 EDT D-Wave Quantum rises 16.7% - D-Wave Quantum is up 16.7%, or $1.10 to $7.70.
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RTX | Hot Stocks12:00 EDT Raytheon Technologies sees R&D tax changes reducing FCF by $6B over 5 years
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HKD | Hot Stocks12:00 EDT AMTD Digital rises 32.2% - AMTD Digital is up 32.2%, or $14.79 to $60.79.
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RTX | Hot Stocks11:59 EDT Raytheon sees structural castings issues lasting through end of year
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RTX | Hot Stocks11:59 EDT Raytheon Technologies sees chip shortages lasting through mid-2023 - Comments taken from the Morgan Stanley 10th Annual Laguna Conference.
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DAL | Hot Stocks11:06 EDT Delta Air Lines CFO says September 'off to a really, really good start' - Speaking at the Morgan Stanley Laguna Conference, Delta Air Lines CFO Daniel Janki said he is "really happy with the progress that the Delta team has been making." Janki stated, according to a transcript of the event: "We talked about it back in July that we took a number of proactive actions in June to reset our second half schedule to set how we do crew scheduling, the set of operational buffers, our airport procedures. And as we progressed here through the summer, July was better than June operationally. August was better than July. And September month-to-date, it's off to a really, really good start to a point where we're running the mainline 99.96% completion factor, continue to lead the industry across those metrics year-to-date, month-to-date, quarter-to-date. So we're really proud of the progress that the team has made on that front and that we're making. You're seeing it from our customers. Our NPS is very strong. It's above what we targeted. And even our operational metrics is actually better. We didn't or talking about 2019 in a lot of ways, but in September, we're ahead of September of 2019 as it relates to operational performance. So really happy and pleased with where we are."
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SGH | Hot Stocks11:03 EDT Cree LED, Tomar Electronics enter settlement, limited license agreement - Cree LED and Tomar Electronics announced that they have reached a negotiated settlement related to Tomar's use of LED components that infringe Cree LED patents. The financial terms of the agreement are confidential. As part of the settlement, Cree LED granted Tomar a limited license to certain Cree LED patents covering LED components. Tomar and Cree LED have a longstanding collaborative relationship that both companies value, and Tomar was unaware that the LED components at issue, which it had purchased from a third-party supplier, were infringing. Under the circumstances, the parties were pleased that they could arrive at a resolution that both addressed the infringement and enabled them to continue working together.
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IHRT RBLX | Hot Stocks10:48 EDT iHeartMedia launches iHeartLand on Roblox - iHeartMedia (IHRT) opened the gates to iHeartLand on Roblox (RBLX). The company said, "iHeartLand is a one-of-a-kind place where gaming, live events, never-ending entertainment, music and the most popular talent converge to offer fans a premiere interactive experience. Users on Roblox will become music tycoons by collecting sound energy throughout iHeartLand to power their own customized music studio as well as unlock upgrades, fan experiences and rewards. Users can also visit different branded spaces like the State Farm Neighborhood featuring Jake from State Farm and Intel House of Wonder to engage with other avatars, play games and more."
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LEA GM | Hot Stocks10:35 EDT Lear to supply electrification technologies for GM's Ultium platform - Lear Corporation (LEA) announced it has been selected by General Motors (GM) to supply key electrification technologies for the automaker's Ultium global electric vehicle platform. The technologies Lear will provide include: Battery Disconnect Units - BDUs are the primary interface between the battery pack and the vehicle's electrical system. Lear's patent-holding and PACE Award-winning BDU has first-to-market thermal management innovations that enable vehicles to charge faster and drive farther. Intercell Connect Boards - ICBs are the electrical and mechanical frames that hold together multiple individual battery cells to form an integrated battery module. Wire Harnesses - Wire harnesses provide electric voltage and distribute power safely and efficiently throughout the vehicle.
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HKD | Hot Stocks10:34 EDT AMTD Digital Inc - ADR trading resumes
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WNC | Hot Stocks10:33 EDT Wabash, Harbinger to collaborate on transportation, logistics solutions - Harbinger announced a new collaboration with Wabash that aims to leverage Wabash's expertise in composite materials in the last mile delivery space."Electrifying the medium-duty trucking industry will only happen with the commitment of manufacturers, distributors, and technology companies who are actively seeking innovative solutions to define the next frontier of the industry," said John Harris, CEO of Harbinger. "We are working closely with industry leading partners like Wabash to bring the commercial electric vehicles to market that are so desperately needed today to improve supply chain efficiency and reduce environmental impacts."
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LDI | Hot Stocks10:31 EDT LoanDepot appoints Gregory Smallwood as CLO - loanDepot announced Gregory Smallwood has joined the Company as chief legal officer and Corporate Secretary, effective immediately. He will report directly to loanDepot CEO Frank Martell. As chief legal officer, Smallwood will oversee all aspects of the Company's legal strategy, supporting loanDepot's focus on providing exceptional service to its customers, employees, and investors. Prior to loanDepot, Smallwood served as general counsel and executive vice president of Caliber Home Loans.
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HKD | Hot Stocks10:29 EDT AMTD Digital Inc - ADR trading halted, volatility trading pause
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RTX | Hot Stocks10:23 EDT Raytheon Technologies unit awarded Intelligence & Space contract by FAA - Raytheon Intelligence & Space, a Raytheon Technologies business, has been awarded a competitive indefinite delivery indefinite quantity contract from the Federal Aviation Administration with a ceiling value of $375M over the next 10 years. Task orders, valued at $215M, were executed at contract award to provide technical refresh and Dual Frequency Operation upgrades to the FAA's Wide-Area Augmentation System, or WAAS, a space-based precision navigation system, that will enhance safer air travel in support of the National Airspace System. Under the WAAS DFO-2 contract, RI&S will deliver more modern processing, system security, and network architecture, while also adding dual frequency service.
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CCRN | Hot Stocks10:18 EDT Cross Country Healthcare sees path to $3B in revenue, $300M in EBITDA - Comments taken from Investor Day conference call.
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VTAQ | Hot Stocks10:13 EDT Ventoux CCM Acquisition Corp trading resumes
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VTAQ | Hot Stocks10:08 EDT Ventoux CCM Acquisition Corp trading halted, volatility trading pause
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CIDM | Hot Stocks10:02 EDT Cinedigm announces deal with Vidgo to expand Cineverse distribution - Cinedigm announced a new deal with Vidgo, which it said will become "the first virtual MVPD to agree to distribute Cinedigm's flagship streaming service, Cineverse, which will feature a lineup of free ad-supported streaming television channels plus thousands of films and TV series on demand." Vidgo plans to launch Cineverse this Fall, Cinedigm stated.
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SFE | Hot Stocks10:00 EDT Safeguard Scientifics falls -9.8% - Safeguard Scientifics is down -9.8%, or -41c to $3.76.
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LICY | Hot Stocks10:00 EDT Li-Cycle falls -10.8% - Li-Cycle is down -10.8%, or -77c to $6.34.
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CXM | Hot Stocks10:00 EDT Sprinklr falls -11.9% - Sprinklr is down -11.9%, or -$1.49 to $11.00.
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ESTE | Hot Stocks10:00 EDT Earthstone Energy rises 8.3% - Earthstone Energy is up 8.3%, or $1.25 to $16.23.
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CRK | Hot Stocks10:00 EDT Comstock Resources rises 8.8% - Comstock Resources is up 8.8%, or $1.73 to $21.36.
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WTI | Hot Stocks10:00 EDT W&T Offshore rises 10.7% - W&T Offshore is up 10.7%, or 72c to $7.44.
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NRBO | Hot Stocks09:47 EDT NeuroBo Pharmaceuticals trading resumes
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FLS | Hot Stocks09:47 EDT Flowserve falls -6.7% - Flowserve is down -6.7%, or -$2.05 to $28.74.
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KFS | Hot Stocks09:47 EDT Kingsway Financial falls -6.9% - Kingsway Financial is down -6.9%, or -44c to $5.90.
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KOLD | Hot Stocks09:47 EDT ProShares UltraShort Bloomberg Natural Gas falls -9.6% - ProShares UltraShort Bloomberg Natural Gas is down -9.6%, or -$1.17 to $11.05.
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CMP | Hot Stocks09:47 EDT Compass Minerals rises 5.5% - Compass Minerals is up 5.5%, or $2.18 to $41.49.
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WTI | Hot Stocks09:47 EDT W&T Offshore rises 6.0% - W&T Offshore is up 6.0%, or 41c to $7.12.
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BORR | Hot Stocks09:47 EDT Borr Drilling rises 6.6% - Borr Drilling is up 6.6%, or 28c to $4.52.
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NRBO | Hot Stocks09:42 EDT NeuroBo Pharmaceuticals trading halted, volatility trading pause
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KITT | Hot Stocks09:41 EDT Nauticus Robotics Inc trading resumes
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ADTX | Hot Stocks09:41 EDT ADiTx Therapeutics trading resumes
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GPCOU | Hot Stocks09:38 EDT Golden Path Acquisition Corp trading resumes
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PCOR | Hot Stocks09:37 EDT Procore, Quickbase partner for no-code toolkit for enhanced workflows - Quickbase announced a new partnership with Procore Technologies. The partnership empowers Procore users with a powerful no-code toolkit to create unique, real-time applications to enhance workflows and unlock new possibilities within Procore, all without the need of professional developers.
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KITT | Hot Stocks09:36 EDT Nauticus Robotics Inc trading halted, volatility trading pause
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ADTX | Hot Stocks09:36 EDT ADiTx Therapeutics trading halted, volatility trading pause
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EWCZ | Hot Stocks09:35 EDT European Wax Center partners with Tweezerman - European Wax Center is teaming up with the experts in beauty tools, Tweezerman, to further add credibility to their professionally designed wax services. To offer their guests the most precise in-center results, European Wax Center will now use the tools in-suite as the finishing step in their professional wax experience.
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SVFD | Hot Stocks09:34 EDT Save Foods announces new sales with Mexican lime packers - Save Foods announced new commercial adoption of its eco-crop protection treatment by Mexican lime packers following the recent successful completion of several pilot programs in Veracruz, Mexico.
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GPCOU | Hot Stocks09:33 EDT Golden Path Acquisition Corp trading halted, volatility trading pause
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KTYCF | Hot Stocks09:31 EDT Kits Eyecare launches same-day delivery - Kits Eyecare announced that same-day delivery is now available in Vancouver and across the lower mainland on over 70% of products available on KITS.ca. Prescription eyeglasses and contact lens orders received before 12pm are eligible for delivery the same day.
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IMPP | Hot Stocks09:28 EDT Imperial Petroleum announces adjournment of annual meeting - Imperial Petroleum announced that the Annual Meeting of Shareholders of the Company convened on September 14, 2022 has been adjourned, due to lack of requisite quorum, to Thursday, October 13, 2022 at 11:00 a.m. Greek local time at the Company's offices at 331 Kifissias Avenue, Erithrea 14561 in Athens, Greece. The record date for the adjourned annual meeting continues to be July 22, 2022. The Company adjourned the Meeting for the purpose of allowing additional time for shareholders to vote on the proposals as set forth in the Company's proxy statement for the Meeting, dated August 3, 2022, which remains unchanged, and to seek to obtain a quorum. The business scheduled for the re-convened Meeting remains the same as set forth in the Proxy Statement, which is: Proposal 1, the election of one director to hold office until the annual meeting of stockholders in 2025 and such director's successor has been duly elected and qualified; Proposal 2, ratification of the appointment of our independent auditors; and to transact such other business as may properly come before the adjourned 2022 Annual Meeting and any further adjournments or postponements thereof.
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TNP | Hot Stocks09:27 EDT TEN, Ltd. declares dividend of 15c per share - The Company continues the uninterrupted payments of common stock dividends with a new distribution of $0.15 per common share scheduled for December 2022. This reflects the second payment for 2022 which is in line with the TEN's semi-annual dividend policy and represents a 50% increase from the prior base of $0.10 paid in July 2022. Inclusive of this upcoming distribution, TEN has paid common shareholders half a billion dollars in dividends, equating to about $25 million per annum since its 2002 NYSE listing. During the second quarter of 2022, the Company issued, through its ATM program, 460,569 common shares generating $4.8 million.
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CARR | Hot Stocks09:27 EDT Carrier Ventures invests in next-generation sustainable technology startups - Carrier Global has completed three new investments through its Carrier Ventures group. Archilogic, Butlr and Transaera, innovative startups in the healthy and green building space, are the newest additions to the Carrier Ventures investment portfolio of companies selected for their next-generation technology, high-growth potential and sustainability focus.
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DBRG | Hot Stocks09:25 EDT DigitalBridge reinstates dividend with 1c per share - DigitalBridge Group, announced that its Board of Directors has reinstated the Company's quarterly dividend, declaring a cash dividend of 1c per share. The dividend will be payable on October 17 to shareholders of record at the close of business on September 30. "We are pleased to follow through on another commitment to our shareholders and reinstate our quarterly cash dividend," said Marc Ganzi, CEO of DigitalBridge. "Successful execution against our strategic objectives has strengthened DigitalBridge's cash flow profile and significantly improved our long-term earnings potential. While management continues to prioritize reinvesting capital in the company's growth-focused strategy, the addition of a dividend enhances total shareholder return." About DigitalBridge
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BCTX | Hot Stocks09:24 EDT BriaCell partners with Caris Life Sciences to expand patient outreach - BriaCell Therapeutics announces that it has signed an agreement with Caris Life Sciences. Under the terms of the agreement, Caris will help BriaCell with efficient patient identification, accelerating enrollment for its current Phase I/II clinical trial in advanced metastatic breast cancer of certain genetically defined subgroups. The partnership between BriaCell and Caris leverages Caris' Right-In-Time Clinical Trial Network, a group of over 495 oncology sites that are able to quickly identify and enroll eligible patients in biomarker-directed clinical trials. This service offers patients and physicians access to the most cutting-edge precision medicine in development. Additionally, through Caris' comprehensive molecular profiling (Whole Exome and Whole Transcriptome Sequencing), Caris will perform tumor profiling for the patients enrolled in the clinical trial.
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RNVA | Hot Stocks09:23 EDT Rennova Health provides business update - The company said, "Rennova Health CEO Seamus Lagan joined Stock Day host Everett Jolly to provide an update on the business and future plans. Jolly began the interview by referring to the most recent 10Q filed by the Company and noting the improved net revenues and financial condition. He asked if the Company expected to have profitable operations going forward. Lagan responded by confirming that the hospital operations were significantly improved and that he believed that hospital operations would be profitable going forward. He also cautioned that a significant amount of legacy debt and other liabilities remained but pointed to the improvements made in the past year and his belief that improvements would continue. Jolly asked for an update on the recently disclosed plan to expand the business into providing behavioral health services. Lagan confirmed the intention to move forward with this initiative and stated that the Company had recently hired an experienced individual to head up this new business. He also confirmed a focus of the new management in creating a detailed business plan that would, in part identify capital needs, and reminded his listeners that the business would utilize available space in the Company's existing properties. Jolly then asked for an update on the shares of common stock outstanding and asked Lagan if the Company had any plans to effect another reverse stock split. Lagan stated that there were approximately ten billion shares issued and outstanding and that there were two hundred and fifty billion shares authorized meaning that there was no need for a reverse split for the foreseeable future. He confirmed that the Company currently had no plans to complete a reverse split. Jolly ended the interview by asking Lagan what message he would like the Company's shareholders to take away from the interview. Lagan responded by referring to previous disclosures of the intention to stabilize the business and his belief that operations have now been stabilized, and that a capable and experienced management team was now in place, allowing the business to focus on building the behavioral health division and possibly looking at additional acquisitions again going forward."
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EBIX | Hot Stocks09:19 EDT EbixCash launches EbixCash Globetrotter Multicurrency Prepaid Card - EbixCash announced that its Foreign Exchange Division - EbixCash World Money, has launched the EbixCash Globetrotter Multicurrency Prepaid Card. EbixCash World Money is one of the largest sellers of Multicurrency Prepaid cards in India with pre-covid annualized sales of USD 750 million. With the launch of the Globetrotter travel card, it is targeting volumes of USD 1 Billion in 2023. EbixCash Multicurrency travel card is available in 10 different currencies such as USD, GBP, AUD, CHF, SAR, THB, EURO, CAD, AED, SGD. The prepaid travel card is accepted across for POS, ATM, E-com across 7 + million merchants globally. With "Tap & Pay" functionality, this card allows customers to transact seamlessly across all merchants.
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CELC URGN | Hot Stocks09:18 EDT Celcuity appoints Polly Murphy to board of directors - Celcuity announced the appointment of Polly Murphy, D.V.M., Ph.D. to its Board of Directors. Murphy is currently the Chief Business Officer of UroGen Pharma, where she has served since 2020, and a member of Atea Pharmaceuticals' Board of Directors.
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BLNK | Hot Stocks09:16 EDT Blink, City of Newton announce installation of two Blink IQ charging stations - Blink Charging and the City of Newton, Iowa announced the installation of two Blink IQ 200 fast Level 2 charging stations in the city. The Blink-owned chargers were installed in the framework of a grant award from the state of Iowa and as part of the City of Newton's drive to provide more accessible and reliable electric vehicle charging stations.
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SUMO | Hot Stocks09:16 EDT Sumo Logic adds Cloud SIEm to FedRAMP-moderate offering - Sumo Logic announced that Sumo Logic Cloud SIEM is now available as part of the Sumo Logic FedRAMP-Moderate offering. With this designation, Sumo Logic becomes the first cloud-native SIEM to deliver insights into on-premises and cloud environments for public sector organizations to help them navigate the growing global threat landscape. Sumo Logic also announced that it expanded its partnership with CloudHesive, a cloud-based Managed Security Services Provider. "The public sector is advancing to deliver rapid innovation, reliable processes, and ensure secure, agile delivery," said George Gerchow, CSO and SVP of IT, Sumo Logic. "Our relationship with CloudHesive is a natural step forward to help federal and public sector agencies. Together, we will bring cloud-native technologies to enable public sector and higher education institutions to make the right investments, navigate complexity and realize value quickly."
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VERB | Hot Stocks09:15 EDT Stemtech uses VERB technology system for their Stemtech Advance Office - Stemtech Corporation announced the Go-Live date of their Stemtech Advance Office based on the VERB Technology Company system. Stemtech Corporation President and Chief Operating Officer, John Meyer, said "we are extremely happy to announce go-live for Monday, September 19, 2022. It is with great anticipation that we offer this exceptional, leading-edge industry software as a tremendous communication tool for our Independent Business Partners. We are proud to have this partnership with VERB, who provide Stemtech with direct sales recruiting, retention and expansion of business capabilities. The analytics and communication aspects via their interactive video-based sales applications, including live-streaming, are a powerful means to communicate with new prospective customers. This partnership with such a prominent provider is an exciting step and will help drive momentum for Stemtech."
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WTHVF FNV | Hot Stocks09:13 EDT Westhaven Gold arranges financing package with Franco-Nevada - Westhaven Gold (WTHVF) is pleased to announce that it has entered into a financing arrangement with Franco-Nevada Corporation (FNV). Westhaven has agreed to sell a 2% net smelter return royalty to Franco-Nevada for $6,000,000. The NSR applies to all of Westhaven's claims across the Spences Bridge Gold Belt in Southwestern British Columbia, Canada. Westhaven has an option to buy-down 0.5% of the NSR for $3,000,000 for a period of 5 years from the closing of the transaction. Westhaven has also agreed to sell to Franco-Nevada for $750,000 the Talisker Resources Ltd. net smelter return royalty originally granted to Westhaven by Sable Resources. In addition, Franco-Nevada has agreed to subscribe for 2,500,000 shares of the Company at a price of C$0.40 for gross proceeds of C$1,000,000.
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ABML | Hot Stocks09:12 EDT American Battery announces steps to modernize governance, board accountability - American Battery Technology Company announced that the company's board of directors approved and adopted amended and restated bylaws and initiated several new corporate governance policies, including a code of conduct, a related persons transactions policy, and an insider trading policy. "As we continue our sustainable transition to a commercial manufacturing and operations company within the battery metals industry, the board decided the time is right to enhance our governance procedures and bylaws," said Elizabeth Lowery, ABTC's Lead Independent Director and Nominations and Corporate Governance Committee Chair. "We believe these steps will ensure decisions are made in the best interest of all our shareholders and expand engagement opportunities." With the changes reflected in the Amended and Restated Bylaws and the policies, the Board believes ABTC's updates to its corporate governance structure will be more appropriate for ABTC's business going forward as a technology development and commercialization firm.
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WRAP | Hot Stocks09:11 EDT Wrap announces new footage of successful deployment of BolaWrap device - Wrap Technologies shared new agency body cam footage demonstrating another successful outcome from the deployment of the BolaWrap Remote Restraint device. On September 4, 2022, officers of the LaGrange Police Department in Georgia responded to a call of a man acting erratic in the area while operating a vehicle. When the officers arrived on-scene, it was determined that he was under the influence of drugs. The subject was noncompliant and attempting to walk away from the officer's commands. The BolaWrap was deployed to the subject's legs and immediately changed the subject's behavior and de-escalated the situation. "The officers on the scene did a great job of reading the situation and executing the proper deployment of the BolaWrap," said Wrap CEO, TJ Kennedy. "The trained officers of the LaGrange Police Department were able to take a chaotic situation and de-escalate the situation by using the BolaWrap. Each time we see another successful field use, we are encouraged by the real-world evidence that supports our mission to help save lives and careers."
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MREO | Hot Stocks09:10 EDT Rubric Capital issues letter Mereo BioPharma shareholders on governance - Rubric Capital Management , an investment advisor whose funds and accounts collectively own approximately 14% of the outstanding equity of Mereo BioPharma Group issued an open letter to Mereo's shareholders. In its letter, Rubric highlighted Mereo's poor corporate governance and performance, and addressed the Company's many misleading public statements regarding Rubric's attempts to constructively engage with the Board and maximize shareholder value. Additionally, Rubric submitted to the Board a revised requisition for a general meeting of shareholders. Rubric urges the Company to allow shareholders to vote on Rubric's proposals, including its nomination of four highly-qualified candidates to Mereo's Board: Annalisa Jenkins, MBBS, FRCP, Daniel Shames, MD, Marc Yoskowitz, and Justin Roberts.
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VINE | Hot Stocks09:09 EDT Fresh Vine announces Food Lion has added its varietal program at 225 locations - Fresh Vine Wine announced that Food Lion has added its California Cabernet Sauvignon varietal to its 'Limited Reserve' program at 225 Food Lion grocery locations in North Carolina, South Carolina, and Virginia. "I am delighted to announce that Food Lion has chosen Fresh Vine Wine's 92 point rated California Cabernet Sauvignon as the newest addition to its celebrated 'Limited Reserve' collection of fine wines," said Bill Donovan, East Atlantic Division Manager, Fresh Vine Wine. "Food Lion enjoys a leading position in the Grocery Market in its geographic markets, where it is focused on offering its customers fresh, healthy food and beverage choices. The introduction of our 'Better For You' California Cabernet Sauvignon furthers their effort to meet this growing demand for healthy choices without compromising taste. As part of our national grocery channel rollout strategy, Food Lion complements our existing footprint and provides us with premier retail distribution in the Southeastern U.S."
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AMRS | Hot Stocks09:08 EDT Amyris names Elizabeth Dreyer as Chief Accounting Officer - In a regulatory 8-K filing, the company states: "On September 9, 2022, Elizabeth Dreyer agreed to join Amyris, Inc. as its Chief Accounting Officer & Corporate Controller, reporting to Han Kieftenbeld, the Company's Chief Financial Officer, effective October 11, 2022. Ms. Dreyer has over 20 years of U.S. public company accounting experience with more than 10 years of experience as Chief Accounting Officer of public companies. Most recently, she served as Chief Accounting Officer of Travel + Leisure Co., a publicly-traded global provider of hospitality services and travel products and Wyndham spin-off, from June 2018 until September 2022, after joining Wyndham Worldwide Corp. in March 2018. Previously, Ms. Dreyer served as Vice President, Controller and Chief Accounting Officer of Edgewell Personal Care Company, a manufacturer and marketer of consumer products, from January 2015 to March 2018."
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CNTA | Hot Stocks09:08 EDT Centessa announces ODD granted to SerpinPC for treatment of hemophilia B - Centessa Pharmaceuticals announced that the U.S. Food and Drug Administration, FDA, has granted Orphan Drug Designation, ODD, to SerpinPC, a novel inhibitor of activated protein C, APC, for the treatment of hemophilia B. Centessa plans to begin registrational studies of SerpinPC in the fourth quarter of 2022. SerpinPC is a biological drug candidate, based on the serpin family of proteins that is designed to allow more thrombin to be generated by inhibiting APC, thus rebalancing coagulation in hemophilia patients. "We believe SerpinPC has the potential to offer patients with hemophilia B a convenient subcutaneous option that is designed to prevent and reduce bleeds without the risk of thrombosis," said Saurabh Saha, MD, PhD, Chief Executive Officer of Centessa. "This designation from the FDA is an important milestone in the development of SerpinPC and underscores the need for new, innovative treatment options for patients with hemophilia B. We look forward to initiating registrational studies for SerpinPC later this year, as well as reporting the two-year follow-up data from the SerpinPC Phase 2a open label extension study in the fourth quarter."
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PL | Hot Stocks09:08 EDT Planet Labs teams with Taylor Geospatial for studies on food security, defense - Planet Labs PBC announced that they have entered into a multi-year contract with Saint Louis University in support of the Taylor Geospatial Institute, a leading geospatial research collaborative. Bringing together eight midwestern universities and research centers, TGI aims to harness innovation in geospatial science and make scientific discoveries that address global challenges. With access to Planet's satellite data, TGI aims to enable researchers to explore critical issues surrounding global food security, core geospatial science and computation, geospatial health, and national security. "This consortium enables the Taylor Geospatial Institute to tap into the incredibly talented and diverse user community in the St. Louis region as they seek solutions to some of the world's greatest challenges. We look forward to seeing the countless ways these students and researchers will leverage Planet's satellite data to help us ensure security and well-being globally," said Robert Cardillo, Planet Federal Chief Strategist.
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PRGS | Hot Stocks09:06 EDT Progress Software announces latest release of developer tools portfolio - Progress announced the latest release of its developer tools portfolio, including Progress(R) Telerik(R), Progress Kendo UI and Progress Telerik Test Studio. With today's R3 2022 release, Progress introduced Progress ThemeBuilder Pro, enabling developers and designers to implement design systems seamlessly in web applications, delivering a greater level of design consistency without manual coding work. The company also announced advanced capabilities for the top development frameworks including Blazor, .NET MAUI, Angular and React to help developers build consistent, high-quality and accessible UI.
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TWLO | Hot Stocks09:06 EDT Twilio reducing workforce by approximately 11% - In a regulatory filing, Twilio said that on September 12, the compensation and talent management committee of the board of directors of Twilio approved a restructuring plan that is designed to reduce operating costs, improve operating margins, and shift the company's selling capacity to accelerate software sales. The Restructuring Plan includes elimination of approximately 11% of the company's current workforce. The company estimates that it will incur approximately $70-$90 million in charges in connection with the Restructuring Plan, consisting of cash expenditures for employee transition, notice period and severance payments, employee benefits, and related facilitation costs as well as non-cash expenditures related to vesting of share-based awards. Of this amount, $55-$70 million is expected to result in future cash outlays. The company expects that the majority of the restructuring charges will be incurred in the third quarter of 2022 and that the execution of this Restructuring Plan, including cash payments, will be substantially complete by the end of the fourth quarter of 2022.
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SIDU MNTS | Hot Stocks09:05 EDT Sidus Space, Momentus sign MOU to explore launch collaboration - Sidus Space (SIDU) announced that it has signed a memorandum of understanding, or MOU, with Momentus (MNTS) to explore launching its LizzieSat satellites utilizing Momentus' Vigoride Orbital Service Vehicle, or OSV. The MOU also seeks to foster collaboration between the two companies to use their joint capabilities to seek new opportunities together, expanding both firms' reach. Together the firms are discussing undertaking an integrated mission that has characteristics of both a Hosted Payload and Delivery Service. Once in orbit, a Momentus OSV could provide power and data to LizzieSat for deployment, offering mission versatility for customers based on Vigoride's service capabilities in-orbit. Sidus Space is interested in four potential mission launches with Momentus initially. As part of the MOU, the companies will potentially provide and/or source payloads to one another and explore working together on select government solicitations.
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FLYW | Hot Stocks09:05 EDT Flywire partners with Universitas XXI to deliver integrated payment solution - Flywire is announcing the availability of its integration with Universitas XXI, a university management system focused on servicing higher education customers throughout Spain and Latin America. Universitas XXI will extend Flywire's digital education payments platform into its student information system, enabling a seamless payment experience for students and administrators, and supporting both international and domestic payment flows. Flywire integrates directly into the Universitas XXI software, helping universities to automatically power every transaction, ranging from initial application fees, all the way through to tuition payments. Within the familiar Universitas XXI software, students and families can track and make payments in native currencies, and university accounting professionals will be able to see and access all payment information within their system of record.
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TWLO | Hot Stocks09:05 EDT Twilio reducing workforce by approximately 11%
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EXPI | Hot Stocks09:04 EDT eXp Realty continues global expansion, announcing Poland to open in 2022 - eXp Realty, the core subsidiary of eXp World Holdings, announced plans to expand its real estate operations into Poland. This announcement follows the successful launch of four new markets in 2022 including the Dominican Republic, Greece, New Zealand and Chile with Dubai expected to open soon. Upon launch of these new markets, eXp Realty will have a presence in 24 global markets, including its headquarters in the United States. "Poland's recent wave of real estate brokerage consolidation speaks to the attractiveness of its property sector for both foreign and domestic investments," said Michael Valdes, Chief Growth Officer. "With continued rapid growth and resilience in the real estate market, Poland provides eXp Realty an ideal opportunity to establish a strong foothold in the Central and Eastern European region."
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FRNWF | Hot Stocks09:04 EDT Future Publishing appoints Clair Blunt as COO - Future Publishing announced the appointment of Claire Blunt as COO. Claire is currently Chief Advertising Officer and CEO of International for the Guardian Media Group.
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VLCN | Hot Stocks09:03 EDT Volcon appoints Katie Hale as CMO - Volcon announced that Katie Hale has been appointed Chief Marketing Officer. Hale comes to Volcon with a deep understanding and skill set focused on social and digital marketing, omni-channel media, and brand building. Hale, previously head of outdoor sports marketing for The Virtus Solution, an Atlanta-based consulting company, will now take the lead of all marketing efforts at Volcon.
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PUBM | Hot Stocks09:02 EDT PubMatic enters into definitive agreement to acquire Martin - PubMatic announced that it has entered into a definitive agreement to acquire Martin, a media measurement and reporting platform, deepening the company's investment in supply path optimization, SPO. "The digital advertising supply chain of the future must be efficient and effective for both publishers and buyers alike. To this end, over the past several years we have been investing in technology and solutions to enable buyers to efficiently access inventory and audiences from top publishers around the globe," said Rajeev Goel, co-founder and CEO at PubMatic. "By integrating Martin's robust workflow, analytics and optimization capabilities for advertisers and agencies into our platform, we believe we will further accelerate and solidify our position as the platform of choice for buyers, and in turn bring greater advertising revenue to our global publisher base." The acquisition is in response to growing demand from PubMatic's buy-side customers for enhanced tools to take advantage of PubMatic's global omnichannel inventory, including market-leading addressability solutions like Connect and innovative technology to enable SPO. The transaction will be fully funded from existing cash on PubMatic's balance sheet, and is expected to close in mid-September 2022, subject to customary closing conditions.
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BOSC | Hot Stocks09:01 EDT BOS Better Online Solutions receives an order in an amount of $2.7M - BOS Better Online Solutions announced that its Supply Chain Division has received an order for an amount of $2.7M from an Israeli defense-industry customer. Avidan Zelicovski, BOS' President, stated: "This is an order from an existing Israeli customer for delivery through the year 2023. It is an addition to orders totaling $1.1 million that this client has placed since the beginning of the year. This order demonstrates the strong added value of our supply chain services to manufacturers from the defense industry. The Supply Chain division's backlog has now increased to a record level of $20.2 million, as compared to a backlog of $8.9 million in September 2021."
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JMAC | Hot Stocks09:00 EDT Maxpro Capital Acquisition Corp trading resumes
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IPA | Hot Stocks08:54 EDT ImmunoPrecise Antibodies subsidiary announces results from NIAID study - ImmunoPrecise Antibodies announced that its subsidiary, Talem Therapeutics, has shared results of a new study conducted by the National Institute of Allergy and Infectious Disease, or NIAID, part of the National Institutes of Health, or NIH, that has shown the continued resilience of PolyTope TATX-03 in broadly neutralizing SARS-Co-V-2 variants, including two Omicron sublineages that had not been previously tested. This NIAID-conducted pseudovirus-based study has reconfirmed the neutralizing activity of TATX-03 against the European variant of the parental virus and several previously tested variants, including Delta and Omicron sublineages. TATX-03 has now demonstrated its neutralizing activity against the currently spreading BA.2.75 variant. Maintained neutralizing potency was also confirmed for the Omicron sublineage BA.2.12.1, SARS-Co-V-2 variant that had not yet been screened in virus neutralization studies.
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USAU | Hot Stocks08:50 EDT U.S. Gold submitts application for permit to mine for CK Gold Project - U.S. Gold reported that it has submitted an application for a Permit to Mine and the Mine Reclamation Plan to the Wyoming Department of Environmental Quality, or WDEQ, for its proposed CK Gold Project, 20-miles west of Cheyenne. The application and fees were delivered to the WDEQ office on Friday, September 9, 2022, and the initial electronic data transfer of the information supporting the application was provided on Tuesday, September 13, 2022, through access to a data site. The proposed Project has reached an advanced state of engineering, following the publication of the Prefeasibility Study on December 1, 2021, which supports permit submissions. The key permit application is the Permit to Mine and Mine Reclamation Plan, both of which are now available for the WDEQ to start reviewing. Initially, the WDEQ will conduct a completeness review and provide the Company with any deficiencies in content. Thereafter, the technical review process will start, addressing comments and questions that the department might have, which includes commentary that might come from other governmental agencies and the public. The Company, as applicant, may need additional time to respond to questions or provide clarification requested as part of the review. Hence, there is no definitive time as to when a decision will be made with respect to the outcome of the application. For projects where the capital investment exceeds $253.8M, approval is required by the Industrial Siting Division, a department within the WDEQ.
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RCRT | Hot Stocks08:47 EDT Recruiter.com partners with Velocity Global - Recruiter.com Group announced its partnership with Velocity Global, a Global Work PlatformTM that provides a solution for businesses and talent to work with anyone, anywhere, anyhow.
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PRTG | Hot Stocks08:46 EDT Portage Biotech provides research and development update - Portage Biotech provided an update on its research and development programs for its expanded portfolio of immuno-oncology assets, and outlined its forward-looking clinical development goals for the next two years. The company remains focused on advancing two broad platforms, its invariant natural killer T cell agonists and its newly acquired adenosine antagonists, PORT-6 and PORT-7. COVID-related backlogs for activating clinical trial sites and staff shortages have made expansion of the PORT-2 study in the United Kingdom challenging. As a result, the company has prepared a parallel company-sponsored study, IMPORT-201, to be launched in the United States and European Union to mitigate the slowdown in the United Kingdom. This will enable more control of progress on the trials and will also impact timing of data readouts. Ongoing development programs are as follows: iNKT Portfolio - Activating the innate, adaptive immune systems and correcting the tumor microenvironment: PORT-2: The newly designated IMPORT-201 study is a multi-arm study Phase 1/2 trial evaluating PORT-2 in non-small cell lung cancer and refractory melanoma; Data presented at the 2022 American Society of Clinical Oncology meeting in June confirmed MOA and demonstrated preliminary safety , tolerability and single agent activity. During ongoing discussions with melanoma thought leaders in the U.S. and EU, it became clear that the front-line standard of care for melanoma is different in the U.S. than in the UK. As a result, the Company has made a strategic decision to drop the front-line randomized melanoma arms of this study and recruit more patients into the front-line NSCLC randomized comparison portion of the study. The Company anticipates four Phase 2 efficacy readouts from the IMPORT-201 study in both NSCLC and melanoma in 2023 and 2024. PORT 3: The Horizon grant that was funding the PRECIOUS study has ended. The Company is waiting for additional data to determine next steps for development. Adenosine Portfolio - Modulating adenosine pathway in four different ways to determine the optimal approach to maximize the impact mechanism of action on different tumors: The Company believes that leveraging the A2A and A2B pathways, alone or in combination, holds the potential for customized treatment for specific patients and/or tumor types. PORT-6 is a potent, selective and durable A2A antagonist while PORT-7 is a highly selective and potent A2B antagonist. The ADPORT-601 adaptive Phase 1a/1b study will explore PORT-6 and PORT-7 as monotherapies, in combination with one another and possibly in combination with other Portage assets. Phase 1b is designed to explore PORT-6 and PORT-7 monotherapies in an enriched population and in randomized trials vs. standard of care. There is strong interest from academic collaborators in the upcoming ADPORT-601 study and the Company is in the process of setting up multiple collaborations on the platform. The Company also recently announced that the U.S. National Cancer Institute has amended its Cooperative Research and Development Agreement to test the products targeting the adenosine pathway. Clinical Development Goals & Anticipated Readouts: Q4 2022: Data from IMPORT-201 study to be presented at a major scientific conference in November; Activation of the ADPORT-601 adaptive Phase 1a/1b study of PORT-6 in multiple tumor types. 2023: Initiation of IMPORT-201 Phase 2 trial Q1; Submission to a major oncology conference with update on IMPORT-201 data Q2; Addition of PORT-7 in the ADPORT-601 Phase 1a/1b study in multiple tumor types 1H; ADPORT-601 data and IMPORT-201 data presented at a major medical conference Q4. 2024: IMPORT Phase 2 ORR data submitted to a medical conference 1H; ADPORT-601 Phase 1b trial initiation 2H; IMPORT Phase 2 PFS data submitted to a medical conference 2H.
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ATAX | Hot Stocks08:40 EDT America First announces quarterly cash, supplemental BUCs distribution - On September 14, 2022, America First Multifamily Investors announced that the Board of Managers of Greystone AF Manager declared a distribution to the Partnership's Beneficial Unit Certificate holders of $0.57 per BUC. The distribution consists of a regular quarterly cash distribution of $0.37 per BUC plus a supplemental distribution payable in the form of additional BUCs equal in value to $0.20 per BUC. The supplemental distribution will be paid at a ratio of 0.01044 BUCs for each issued and outstanding BUC as of the record date, which represents an amount per BUC based on the closing price of the BUCs on the Nasdaq Stock Market LLC on September 13, 2022 of $19.15 per BUC. No fractional BUCs will be issued in connection with the supplemental distribution, as all fractional BUCs resulting from the distribution with a fraction equal to or above 0.5 will be rounded up to the next higher BUC, and fractional BUCs with a fraction less than 0.5 will receive cash for such fraction based on the market value of the BUCs on the record date. The Partnership expects to issue an aggregate of approximately 230,500 BUCs in the supplemental distribution. The cash distribution and supplemental distribution will be paid on October 31, 2022 to all BUC holders of record as of the close of trading on September 30, 2022. The BUCs will trade ex-distribution as of September 29, 2022
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BIAF | Hot Stocks08:38 EDT Bioaffinity presents its research in flow cytometry analysis of sputum - BioAffinity Technologies announced publication of its research in high-throughput flow cytometry analysis of sputum. The journal PLOS ONE, published Sputum analysis by flow cytometry; an effective platform to analyze the lung environment reporting on results of analyzing sputum by flow cytometry as the basis for high-throughput diagnostic tests to determine the health of the lung. "The PLOS ONE paper presents our unique method for determining the health of an individual's lungs," bioAffinity President and CEO Maria Zannes said. "Flow cytometry allows for analysis of whole cells and cell populations that make up the lung environment. Our research provides a better understanding of how disease changes the lung environment and how flow cytometry can be used as a diagnostic tool by analyzing sputum. Flow cytometry is successfully used to diagnose blood cancers, particularly at early stage. In the paper, we describe an innovative and highly efficient method to analyze sputum for the presence of lung cancer, with the potential to focus on other diseases such as COPD and asthma."
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COHR | Hot Stocks08:38 EDT Coherent introduces I-Temp micro-pump lasers for extended temperature operation - Coherent announced the introduction of its I-Temp micro-pump lasers for extended ambient temperature operation in broadband optical access networks. Coherent's new I-Temp micro-pump lasers are now capable of operating over the extended temperature range of -40 to 85 degrees Celsius, enabling optical amplifiers deployed at the network edge to withstand extreme weather conditions. "The combination of small size, wide operating temperature, and low power consumption makes the I-Temp micro-pump a perfect solution for environmentally hardened optical amplifiers installed, for example, on utility poles," said Dr. Richard Smart, Senior Vice President, ROADM Business Unit. "The I-Temp micro-pump leverages differentiated technology at every level of its vertically integrated design, including our GaAs semiconductor laser technology platform, with its proven reliability through decades of field deployments."
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KULR | Hot Stocks08:36 EDT KULR Technology announces it has joined NAATBatt International - KULR Technology Group announced it has joined NAATBatt International, NAATBatt, the trade association of developers, manufacturers, suppliers and users of battery technology in North America. As a platinum member, KULR will regularly participate in board meetings, allowing the company to connect with top policy makers in the space, discuss and develop cutting-edge technological advancements and remain at the forefront of battery technology. "KULR is at an inflection point as we position our thermal safety solutions platform to become further entrenched in the marketplace, ultimately providing us with an opportunity to optimize logistics as we continue investing in the localization of our production and supply chain to North America," said Michael Mo, Co-Founder and CEO of KULR Technology Group. "Becoming a member of NAATBatt allows us to further that mission. We'll learn and participate in the development of innovative solutions for the advancement of battery technologies, become better positioned to meet market needs and benefit from local policy support."
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KDP | Hot Stocks08:35 EDT Keurig Dr Pepper raises annual dividend 6.7% to 80c - Keurig Dr Pepper announced that its Board of Directors has approved a 6.7% increase in its annualized dividend rate to 80c per share, from the current annualized rate of 75c per share, effective with the regular quarterly cash dividend. The 6.7% increase, combined with the previous dividend increase announced in February 2021, will result in a 13.0% increase versus year-ago in cash dividends paid in 2022. The increased regular quarterly cash dividend of 20c per share is payable in U.S. dollars on the Company's common stock on October 14 to shareholders of record on September 30.
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JMAC APLM | Hot Stocks08:35 EDT Apollomics, Maxpro Capital Acquisition enter business combination agreement - Apollomics and Maxpro Capital Acquisition Corp. announced a definitive agreement for a business combination that would result in Apollomics becoming a publicly traded company on the Nasdaq Global Market. The business combination is expected to close in the first quarter of 2023 and Apollomics is expected to be listed on Nasdaq under the ticker symbol "APLM." Apollomics' broad pipeline of drug candidates includes late-stage clinical assets for the treatment of patients with difficult-to-treat cancers. Apollomics' mission is to develop assets in critically important areas of unmet need. The Company's leading drug candidates address certain subpopulations within lung cancer and leukemia. Globally, both lung cancer and leukemia affect over 2 million people annually. The Company is dedicated to discovering and developing oncology therapies of different mechanisms of action to inhibit cancer. Its diverse portfolio of innovative drug candidates for treating difficult-to-treat cancers includes precision therapy targeting tumors with specific mutations, as well as assets addressing broader cancer conditions. The Company's pipeline of nine clinical, preclinical and discovery drug candidates has the potential to improve treatment of a number of tumor types. Upon the closing of the transaction, Apollomics will continue to be led by current Chairman and CEO, Dr. Guo-Liang Yu, Ph.D., a serial entrepreneur, and his team. Dr. Yu is a pharmaceutical researcher with more than 300 patents. Apollomics expects results from its global Phase 2 multi-cohort clinical trial of vebreltinib in NSCLC and other solid tumors with cMET dysregulation in 2023, which the Company believes may support its first New Drug Application with the U.S. Food and Drug Administration while generating clinical data for different indications. In addition, the Company expects to complete patient recruitment of its uproleselan Phase 3 study in China in 2023. Upon the closing of the Transaction, Apollomics will become a publicly traded company under the name "Apollomics Inc." The Transaction reflects an implied pre-money equity value of approximately $899M. Upon the closing of the Transaction and assuming no redemptions by Maxpro's public stockholders, Apollomics plans to retain up to $105M of cash, being expected proceeds from realization of marketable securities held in the Trust Account, on its balance sheet, which would provide financial flexibility and facilitate internal and external growth opportunities. At the closing of the Business Combination and assuming no redemptions by Maxpro's public stockholders, approximately 10% of the outstanding shares of the combined company are expected to be held by public investors, with existing Apollomics shareholders owning approximately 87%. The Transaction has been unanimously approved by the boards of directors of Maxpro and Apollomics. The completion of the Transaction is subject to customary closing conditions, including the approval of Maxpro's stockholders and the satisfaction of a $20M minimum cash condition. The Transaction is expected to close during the first quarter of 2023.
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HST | Hot Stocks08:35 EDT Host Hotels publishes 2022 CR report, introduces 2050 CR vision - Host Hotels & Resorts released its 2022 Corporate Responsibility, CR, Report, which details the Company's CR program and responsible investment strategy along with its environmental, social and governance, ESG, performance, progress and industry-leading accomplishments. Additionally, the 2022 CR Report introduces the framework for the Company's 2050 CR vision. Joanne Hamilton, executive vice president of human resources and corporate responsibility said, "While we continue to make significant progress toward our social and environmental targets, we are looking beyond 2025 and taking steps for Host to contribute to a more sustainable world. We are excited to share our 2050 aspiration of becoming a net positive company, along with our progress across business and society-critical issues."
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MGPI | Hot Stocks08:33 EDT MGP Ingredients names Landherr Chief Legal Officer - MGP Ingredients has named attorney Curtis Landherr as its Chief Legal Officer, CLO. Landherr brings over 25 years of law firm and in-house legal experience across a variety of industries to the new role, which he will start October 17, 2022. Most recently, Landherr served as Senior Vice President and General Counsel at Cirrus Aircraft where he created, managed and grew the legal function beginning in 2014.
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AMWL | Hot Stocks08:33 EDT Amwell appoints Matthew McAllister as Chief Product Officer - Amwell announced the appointments of Vaughn Paunovich to the role of Executive Vice President, Enterprise Platforms, and Matthew McAllister to Chief Product Officer. Vaughn will oversee technological delivery and innovation, including for Converge(TM), Amwell's enterprise grade digital care delivery platform, and Matthew will join Vaughn's leadership team with responsibility for product management and design.
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CVLT | Hot Stocks08:33 EDT Commvault appoints Alan Atkinson as Chief Partner Officer - Commvault announced that data protection industry veteran Alan Atkinson has joined the company as Chief Partner Officer. Atkinson will report to Riccardo Di Blasio, Commvault's Chief Revenue Officer. Atkinson brings a wealth of cloud and data protection experience to Commvault - from building the industry's first, pre-eminent cloud service provider to leading WysDM Software until it was acquired to driving technology strategy and commercial sales at Dell. Under his leadership, Commvault will further strengthen the company's strategic alliances with cloud partners and continue to galvanize and grow its partner program.
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PM | Hot Stocks08:32 EDT Philip Morris increases quarterly dividend to $1.27 per share - The board of directors of Philip Morris has increased the company's regular quarterly dividend by 1.6% to an annualized rate of $5.08 per share. The new quarterly dividend of $1.27 per share, up from $1.25 per share, is payable on October 12 to shareholders of record as of September 28. The ex-dividend date is September 27, 2022.
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PFSW LRLCY | Hot Stocks08:32 EDT PFSweb deploys pop-up fulfillment operation for L'Oreal brand SkinCeuticals - PFS, a premier eCommerce order fulfillment provider and business unit of PFSweb (PFSW), announced they recently deployed a pop-up fulfillment center for one of their L'Oreal (LRLCY) USA brands, SkinCeuticals."This project was a fantastic example of the flexibility and efficiency our fulfillment innovations bring to the market," commented Zach Thomann, COO and President of PFS. "RetailConnect and our other fulfillment-as-a-service products are created using the same technology and processes deployed within our core order fulfillment operations. With a lightweight design and simple integration, they can be deployed into numerous working environments to facilitate an effective and cost-efficient pick-pack-ship operation. We appreciate the opportunity SkinCeuticals gave us to demonstrate the effectiveness of RetailConnect in solving their challenge and look forward to additional opportunities in the future."
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WETF | Hot Stocks08:31 EDT WisdomTree launches Blockchain UCITS ETF - WisdomTree announced the launch of WisdomTree Blockchain UCITS ETF. Listed on the London Stock Exchange, Borse Xetra and Borsa Italiana, WBLK seeks to track the price and yield performance, before fees and expenses, of the WisdomTree Blockchain UCITS Index and has a total expense ratio of 0.45%.
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RGTI | Hot Stocks08:29 EDT Rigetti Computing launches Rigetti QCS on Microsoft's Azure Quantum platform - Rigetti Computing announces that it has launched Rigetti QCS in Public Preview on Microsoft's Azure Quantum platform. Previously in Private Preview, all Azure Quantum users can now access Rigetti's Aspen-M-2 80-qubit and Aspen-11 40-qubit superconducting quantum processors on demand to develop and run quantum applications.
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REAX | Hot Stocks08:28 EDT Chime extends relationship with The Real Brokerage Inc. - Chime Technologies announced The Real Brokerage has engaged with the company to serve as the organization's customer relationship management platform of choice.
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ALT | Hot Stocks08:28 EDT Altimmune down 58% in pre-market after results of Phase 1b study of pemvidutide - Shares of Altimmune are down 57% or $11.58 at $8.80 in pre-market trading after the company announced topline results from its 12-week Phase 1b study of pemvidutide in subjects with non-alcoholic fatty liver disease, NAFLD, even though the trial met its primary endpoint in all pemvidutide treatment groups.
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JMAC | Hot Stocks08:25 EDT Maxpro Capital Acquisition Corp trading halted, news pending
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RIBT | Hot Stocks08:22 EDT RiceBran regains compliance with Nasdaq bid price rule - RiceBran Technologies received formal notification from The Nasdaq Stock Market that the Company has regained compliance with Listing Rule 5550(a)(2), which requires the Company's common stock to maintain a minimum bid price of $1.00 per share. The Nasdaq staff made this determination of compliance after the closing bid price of the Company's common stock was at $1.00 per share or greater for the prior 10 consecutive business days. Nasdaq had previously notified the Company of its non-compliance with Listing Rule 5550(a)(2) on September 15, 2021. In accordance with its Listing Rules, Nasdaq afforded the Company 180 calendar days to regain compliance. On March 15, 2022, the Company received a 180-day extension from the Nasdaq to meet continuing listing requirements by maintaining a minimum bid price per share of $1.00 for a minimum of 10 consecutive business days. The Company had until September 12, 2022 to meet Nasdaq's Minimum Bid Rule. Prior to the expiration of the compliance period, the Company successfully regained compliance with the listing standard.
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PRDS | Hot Stocks08:20 EDT Pardes Biosciences appoints Smaldone, Pottage to board of directors - Pardes Biosciences announced the appointments of Laurie Smaldone Alsup, M.D. and John C. Pottage, Jr., M.D. to its Board of Directors. Dr. Smaldone Alsup has over 30 years of biopharmaceutical industry experience. She currently serves as the Chief Medical Officer and Chief Scientific Officer of NDA Group AB. Dr. Pottage brings over 20 years of executive and clinical development experience. He most recently served as Chief Medical Advisor of Clear Creek Bio.
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OBNNF | Hot Stocks08:20 EDT Osisko Mining files technical report for Windfall MRE update - Osisko Mining is pleased to announce that it has filed a technical report in accordance with National Instrument 43-101 - Standards of Disclosure for Mineral Projects to update the mineral resource estimate on its 100% owned Windfall gold deposit. The technical report entitled " Mineral Resource Estimate Update for the Windfall Project, Eeyou Istchee James Bay, Quebec, Canada" and dated September 14, 2022 has been prepared for Osisko by BBA Inc. The technical report is available on SEDAR under Osisko's issuer profile. The technical report contains a non-material change from the news release published on August 30, 2022. Sensitivity Table 1 has been corrected for the 2.5g/t cut-off grade. This change does not impact the results of the August 30, 2022 news release as the modification affects only numbers presented for reference purposes in the news release. The NI 43-101 Technical Report cut-off grade has been determined with reference to a 3.5g/t cut-off grade.
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RVSN | Hot Stocks08:19 EDT Rail Vision completes pilot at with Rio Tinto Iron Ore for AutoHaul project - Rail Vision announced the completion of a pilot with Rio Tinto Iron Ore for the AutoHaul project, the world's first automated, long distance, heavy haul rail network. Rail Vision's Main Line System test in Pilbara, Australia began in May 2022 as part of the Company's contract with Hitachi Rails STS, the lead project technology partner and integrator. "We are excited to expand our long-term pilot program with Rio Tinto and evaluate additional use cases for the AutoHaul project, which is at the forefront of the future of autonomous train operations," commented Shahar Hania, CEO and co-founder of Rail Vision. "Early successes with the initial long-term pilot program announced in May was a key factor in moving forward with additional testing programs through the now-expanded pilot program. We look forward to continuing operational testing with Rio Tinto." As part of the AutoHaul project, 2.4-kilometer-long trains, monitored remotely from an operations center in Perth, Australia, travelled across a vast network of 1,700 kilometers of track, delivering iron ore from 16 mines to ports in Dampier and Cape Lambert.
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FRSH | Hot Stocks08:18 EDT Freshworks director buys $11.5M in common stock - In a regulatory filing last night, Freshworks disclosed that its director Sameer Gandhi bought 786.6K shares of common stock on September 9th in a total transaction size of $11.5M. Shares of Freshworks are up 3.4% in pre-market trading at $14.90.
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HEPA | Hot Stocks08:17 EDT Hepion Pharmaceuticals announce research collaborators to present new findings - Hepion Pharmaceuticals announced that its research collaborators from London's Institute of Hepatology will present new findings on the Company's cyclophilin inhibitor, rencofilstat, in an awarded oral presentation at the 2022 joint meeting of the International Society for Biomedical Research on Alcoholism, ISBRA, and European Society for Biomedical Research on Alcoholism, ESBRA, taking place September 17-20, 2022 in Cracow, Poland. The study to be presented evaluated the effects of rencofilstat in human tissue-derived experimental models of ALD, and on fibrosis in primary hepatic stellate cell cultures. In addition to reducing alpha-smooth muscle actin and improving collagen fiber alignment in HSCs, rencofilstat reduced the expression and secretion of pro-fibrogenic markers and restored a balanced cytokine profile in patient-matched precision cut liver slices exposed to hepatotoxic insults. "These data confirm the role of cyclophilins in liver fibrosis - including HSC activation, collagen deposition and orientation - while also revealing, for the first time, rencofilstat's therapeutic potential to reduce ALD-induced fibrosis," said Dr. Robert Foster, PharmD, PhD, Hepion's CEO.
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BASFY | Hot Stocks08:17 EDT BASF, X-ELIO sign power purchase agreement for Freeport site - BASF and X-ELIO have signed a 12-year Power Purchase Agreement to supply 48 megawatts of solar power to BASF's Verbund site in Freeport, Texas. With this agreement in place, 100% of the site's expected purchased power will be supplied from renewable energy. The project will further reduce carbon emissions at the BASF Freeport site and offset more than 82,000 metric tons of CO2 emissions annually, based on EPA estimates. Freeport is one of BASF's six global Verbund sites, which takes an integrated approach to manufacturing, research and the overall management philosophy. Together with the maximum integration of infrastructure, processes, talent, energy and waste management, this philosophy creates a highly efficient manufacturing site.
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EFTR | Hot Stocks08:15 EDT eFfector doses first patient in second cohort of Phase 1b trial of zotatifin - eFFECTOR Therapeutics announced it has dosed the first patient in the second cohort of its Phase 1b clinical trial of zotatifin in non-hospitalized adults with confirmed COVID-19 infection. The study is a double-blind, randomized, placebo-controlled trial evaluating the safety and antiviral activity of a single dose of zotatifin and is being conducted in collaboration with the Quantitative Biosciences Institute at the University of California, San Francisco, under a $5M cooperative agreement sponsored by the Defense Advanced Research Projects Agency. Steve Worland, Ph.D., president and chief executive officer of eFFECTOR said, "Administered as a single dose injection, zotatifin aligns with the Test to Treat initiative being promoted by the U.S. government and has the potential to overcome many of the limitations of existing treatment options, including poor treatment adherence that can result in viral rebound. Achieving equivalent drug levels when zotatifin was delivered by the sub-cutaneous route provides an opportunity for convenient dosing in both the COVID and cancer settings."
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IMMP | Hot Stocks08:15 EDT Immutep sees cash runway into early 2024 - Including the planned program expansion, Immutep remains well-funded with ~$80 million in cash as of 30 June 2022, providing a cash runway into early CY2024.
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IMMP | Hot Stocks08:15 EDT Immutep provides clinical development update on eftilagimod alpha - Immutep provides a clinical development update for its first-in-class LAG-3 antigen-presenting cell activator product candidate, eftilagimod alpha. Pathway in Lung Cancer: Immutep is prioritising 1L NSCLC in terms of late-stage clinical strategy, based on compelling data, coupled with the large market opportunity and continued high unmet need for more durable and tolerable options. In combination with top selling drug in oncology, Keytruda, efti has been delivering strong results, especially in patients known to respond less than optimally/sub-optimally to anti-PD-1 treatment. Immutep's next steps in NSCLC will be shaped by the maturing TACTI-002 data, with additional data expected in Q4 2022 and feedback from regulatory authorities. Initial results from Immutep's ongoing INSIGHT-003 trial evaluating efti in combination with anti-PD-1 therapy and chemotherapy are also expected in Q4 2022. These results may help to further inform the design of our late-stage trial in 1L NSCLC. Pathway in Head and Neck Cancer: Currently, 47/154 patients have been recruited into Immutep's ongoing randomised Phase IIb TACTI-003 trial in 1L HNSCC. Recruitment is accelerating as further sites have been activated. The trial is being conducted in collaboration with Merck. Efti in 1L HNSCC has Fast Track designation by the FDA, which provides Immutep with access to more frequent meetings and communications with the FDA, and potentially enables Rolling Review of a Biologic License Application. In addition, Fast Track designation may provide Accelerated Approval and Priority Review if relevant criteria are met, for efti in HNSCC. Pathway in Breast CancerL Immutep will continue with preparations for future clinical development in MBC, including engagement with the regulators, Contract Research Organisations and other stakeholders, each of which are progressing. Efti has shown encouraging clinical data in combination with chemotherapy in this indication, including statistically significant improvements in overall survival across several pre-defined subgroups. As such, MBC remains an attractive opportunity for efti. Ultimately, Immutep will aim to obtain marketing authorisation of efti in multiple indications, positioning the Company, or a potential partner, strongly to fully exploit the compelling potential of this unique clinical candidate to help a wide range of cancer patients. Upcoming Clinical Data Updates Immutep plans to provide further clinical trial updates in Q4 2022, as follows: more data from TACTI-002 in 1L NSCLC, first results from the INSIGHT-003 study, and an update from the TACTI-003 study. In addition to Immutep's current development program, the company is also engaged in discussions with a number of external parties to test efti in new settings. The expansion of clinical settings will help to further explore the potential of efti and enhance its value. A first example is the recently announced new Phase II investigator-initiated study in soft tissue sarcoma with efti in combination with pembrolizumab and radiotherapy in the neoadjuvant setting. We hope to have further updates regarding these potential new settings in the coming weeks.
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LFMD BMRA | Hot Stocks08:13 EDT LifeMD expands primary care platform's diagnostic capabilities - LifeMD (LFMD) announced the continued expansion of its primary care platform's diagnostic capabilities with new offerings that include at-home screening kits for early warning signs of colon and breast cancer. LifeMD's new offerings feature the Aware Breast Self Exam pad for breast exams and the EZ Detect at-home test that can detect an early warning sign of colon cancer. Both kits are from Biomerica (BMRA). "We believe telehealth can play an essential role in diagnostic care and early detection as part of regular medical self-care, which is why LifeMD offers these at-home screening kits for free as part of the LifeMD membership. We're thankful for our strategic partnerships that allow us to provide innovative treatments and diagnostics to our patients," continued LifeMD CEO Justin Schreiber.
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AYTU | Hot Stocks08:13 EDT Aytu BioPharma adds fourth patent license for AR101/Enzastaurin - Aytu BioPharma announced the addition of a fourth patent to the intellectual property suite surrounding AR101/Enzastaurin. This fourth patent, also licensed from Johns Hopkins University, is titled "Pathway Targets for the Treatment of Vascular Ehlers-Danlos Syndrome," expands the scientific evidence of the pathophysiology of Vascular Ehlers-Danlos Syndrome and is highly confirmatory of the therapeutic approach for AR101/Enzastaurin. The patent has an expiry date of September 2041, assuming no patent term extensions."We're excited about the continued evidence being generated in support of AR101/Enzastaurin for the treatment of VEDS," remarked Josh Disbrow, Chief Executive Officer of Aytu BioPharma. "Adding this fourth patent to the portfolio deepens and broadens the intellectual property surrounding AR101/Enzastaurin for the treatment of inherited vascular disorders, including VEDS, for which we are advancing AR101 as an initial indication. We expect to advance the PREVEnt Trial in VEDS for AR101 and dose the first patient by early 2023."
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ALDX | Hot Stocks08:12 EDT Aldeyra provides update on pre-NDA meeting for RASP modulator reproxalap - Aldeyra announced that, following the recent receipt of official minutes from its pre-NDA meeting with the FDA, the company remains on schedule to submit an NDA in the fourth quarter of 2022 requesting marketing approval of the novel RASP modulator reproxalap, an investigational new drug, for the treatment of dry eye disease. Consistent with prior guidance, with results from five adequate and well-controlled completed clinical trials, Aldeyra intends to submit the NDA with data for ocular dryness symptom score, ocular redness, Schirmer test, and Schirmer test greater than or equal to10 mm responder analysis. The NDA efficacy package is expected to include activity ranging from within minutes of drug administration to up to 12 weeks of treatment, crossover and parallel-group clinical trial designs, and assessment in dry eye chamber challenge and natural environment settings. In addition to efficacy data, Aldeyra plans to submit up to 12 months of safety data. Topical ocular reproxalap has been studied in more than 2,000 patients with no observed safety concerns; mild and transient instillation site irritation is the most commonly reported adverse event in clinical trials. In addition to the planned NDA submission for reproxalap in dry eye disease, Aldeyra highlighted the following expected upcoming corporate milestones: The pre-NDA meeting for ADX-2191 for the treatment of primary vitreoretinal lymphoma has been scheduled for the fourth quarter of 2022. Results from Part 1 of the Phase 3 GUARD trial of ADX-2191 in proliferative vitreoretinopathy are expected in the third or fourth quarter of 2022. Results from the Phase 2 clinical trial of ADX-2191 in retinitis pigmentosa are expected in the first half of 2023. Results from the Phase 3 INVIGORATE-2 trial of reproxalap in allergic conjunctivitis are expected in 2023.
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CLBS LSTA | Hot Stocks08:11 EDT Caladrius announces approval of merger, name change to Lisata Therapeutics - Caladrius Biosciences (CLBS) announced that, based upon the final vote count certified by the independent inspector of elections for the annual meeting of stockholders held September 13, 2022, its stockholders approved all of the merger-related proposals, including: the Agreement and Plan of Merger and Reorganization, dated as of April 26, 2022, by and among Caladrius and Cend Therapeutics, and the transactions contemplated thereby, including the Merger and the issuance of shares of Caladrius' common stock to Cend's stockholders pursuant to the Agreement and Plan of Merger and Reorganization, an amendment to the amended and restated certificate of incorporation of Caladrius to effect a reverse stock split of Caladrius' common stock, at a ratio mutually agreed to by Caladrius and Cend in the range of one new share for every five to fifteen shares outstanding, and an amendment to the amended and restated certificate of incorporation of Caladrius to change the corporate name of the Company from "Caladrius Biosciences, Inc." to "Lisata Therapeutics, Inc." Subsequent to the stockholders' approval, the Caladrius Board of Directors approved a reverse stock split of Caladrius' common stock at a ratio of one new share for every fifteen shares outstanding. The reverse stock split will become effective today, September 14, 2022, at 5:00pm EST. Subject to the satisfaction of customary closing conditions, the closing of the merger with Cend is expected to occur on September 15, 2022. The consolidated common shares for the combined company, which will be renamed Lisata Therapeutics, Inc., are expected to commence trading on The Nasdaq Capital Market under the symbol "LSTA" on September 15, 2022, at 9:30am EST.
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MSSTF | Hot Stocks08:10 EDT Mindset Pharma receives scientific advice from MHRA on Phase 1 trial of MSP-1014 - Mindset Pharma announced that the Company has received Scientific Advice from the UK Medicines and Healthcare products Regulatory Agency on a range of points to finalize its Phase 1 first-in-human clinical trial plan evaluating its lead psychedelic drug candidate MSP-1014 for the treatment of Major Depressive Disorders. In a meeting with the MHRA, Mindset discussed its plans for Phase 1 first-in-human clinical development of MSP-1014, a novel and patented, second-generation psilocybin-like drug candidate within Family 1, in collaboration with a specialized psychedelic UK-based Contract Research Organization, Clerkenwell Health. The MHRA has agreed with the Company's position and confirmed that, subject to CTA review, MSP-1014 will not require additional preclinical studies at this time. The MHRA has also provided specific valuable guidance on potential clinical trial design regarding dosing, patient selection criteria, and safety endpoints. In preclinical studies, MSP-1014, demonstrated an improved efficacy and safety profiles, with reduced potential side effects and faster onset of action, and similar duration of effect compared to the first-generation drug candidate psilocybin. Given its differentiation and improved pharmacological profile, Mindset prioritized moving MSP-1014 to first-in-human clinical studies.
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ADVM | Hot Stocks08:09 EDT Adverum Biotechnologies announces first subject dosed in LUNA Phase 2 trial - Adverum Biotechnologies announced that the first subject was dosed in the LUNA Phase 2 trial evaluating ixoberogene soroparvovec for the treatment of wet age-related macular degeneration, wet AMD. "Dosing the first subject in the Phase 2 LUNA study brings us a step closer to our mission of establishing gene therapy as a new standard of care for some of the leading causes of vision loss," stated Richard Beckman, M.D., chief medical officer of Adverum Biotechnologies. "The trial is designed to assess the safety and efficacy of two dose levels of a single, in-office intravitreal injection of Ixo-vec for the treatment of wet AMD. We are excited that LUNA will allow us to explore a new, lower 6E10 dose that we hope will build on the robust, durable efficacy and safety profile already demonstrated with the 2E11 dose in the OPTIC trial. We will also be evaluating two enhanced local prophylactic steroid regimens with and without the use of systemic steroids to determine the most effective prophylactic regimen and dose pairing to optimize risk benefit. During 2023, we anticipate reporting initial data from the study, including aflibercept protein expression at Week 10, which we have found in the OPTIC trial to be predictive of long-term expression out to at least three years, and an interim analysis at Week 26." The LUNA trial is a double-masked, randomized, Phase 2 trial being conducted at approximately 40 sites in the U.S. and Europe. Up to 72 subjects will be randomized equally between the 2E11 Ixo-vec dose and new lower 6E10 dose and across four prophylactic steroid regimens. Specific regimens being evaluated include topical difluprednate, IVT dexamethasone, or a combination of either topical Durezol or IVT Ozurdex with oral prednisone, with the aim of establishing a prophylactic regimen with minimal need for inflammation management post prophylaxis. The LUNA trial primary endpoints are mean change in BCVA from baseline to one year and the incidence and severity of adverse events. Key secondary objectives include the mean change in central subfield thickness from baseline to one year and assessing the effectiveness of prophylactic steroid regimens on minimizing inflammation.
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TRQ | Hot Stocks08:09 EDT Turquoise Hill says federal court in NY dismisses all claims from class action - Turquoise Hill Resources announces that a federal court in New York has dismissed all claims made against the Company and three of its current or former executives in a putative class action, backed by Pentwater Capital Management , filed in October 2020. The lead plaintiff in the case, a group of private investment funds advised by Pentwater alleged in its complaint that the Company and three of its executives had violated United States securities laws by making false or misleading statements about the progress and expected cost of the development of the Oyu Tolgoi underground mine in Mongolia. The Pentwater Funds brought the claims on behalf of a putative class of investors who purchased Turquoise Hill securities from July 17, 2018, to July 31, 2019, in the United States.
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HZNP | Hot Stocks08:08 EDT Horizon Therapeutics announces publication of MIRROR trial data - Horizon Therapeutics announced the publication of data from the MIRROR randomized controlled clinical trial of Krystexxa injection with methotrexate, a commonly used immunomodulator, in Arthritis & Rheumatology. The co-administration of Krystexxa with an immunomodulator like methotrexate has increasingly been employed for patients with uncontrolled gout to help reduce the development of anti-drug antibodies, which can affect treatment efficacy. Following a series of case studies and an open-label study, the MIRROR randomized controlled trial was conducted and evaluated differences in treatment response for Krystexxa with methotrexate compared to Krystexxa with placebo. The primary endpoint was the proportion of serum uric acid responders defined as sUA less than6 mg/dL for at least 80% of the time during Month 6. The study's secondary endpoints included the proportion of sUA responders during Month 12, defined as sUA less than 6 mg/dL for at least 80% of the time, and the proportion of participants with complete resolution of at least one tophus with no new tophus and no single tophus showing progression at Week 52 in subjects with tophi at baseline. Greater than 30 percentage-point increase in patient response rate during Month 6: 71% of patients randomized to receive Krystexxa with methotrexate vs 39% of patients randomized to receive Krystexxa with placebo achieved the primary efficacy endpoint. Marked reduction in infusion reactions: during the treatment period, 4% of patients who received Krystexxa with methotrexate experienced infusion reactions vs 31% of patients who received Krystexxa with placebo. No new safety signals were observed. Over a 20 percentage-point increase in the complete resolution of at least one tophus at Week 24: among patients with validated tophi at baseline, 35% of patients who were randomized to receive Krystexxa with methotrexate had complete resolution of at least one tophus at Week 24 vs 14% of patients who were randomized to receive Krystexxa with placebo. Concentrations of methotrexate polyglutamates were maintained during the treatment course for patients randomized to receive Krystexxa with methotrexate, confirming compliance with methotrexate therapy. In addition, methotrexate polyglutamate concentrations were in the same range as those reported for oral methotrexate use in patients with rheumatoid arthritis. A total of 152 participants were randomized 2:1 to a four-week run-in and treatment period with oral methotrexate or placebo, followed by bi-weekly infusions of Krystexxa with either methotrexate or placebo for 52 weeks. The mean patient age was 55 years. At screening, patients had on average a 14-year history of gout, 76% of patients had an investigator-identified tophi, and all had experienced at least one gout flare in the prior year. In addition, comorbidity prevalence was high, with hypertension, gastrointestinal disorders and stage 3 chronic kidney disease noted most frequently. Baseline characteristics were balanced across treatment groups.
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BNGO | Hot Stocks08:08 EDT Bionano Genomics announces publication of study in MDS, AML - Bionano Genomics announced the publication of a study evaluating the performance of OGM for detection of cytogenetic abnormalities in myelodysplastic syndromes and acute myeloid leukemia samples. This work is the second independent study, following a recent publication from researchers at MD Anderson Cancer Center, showing that OGM enables better molecular characterization of MDS. This paper extends that research to AML and the findings indicate that OGM may have an even greater impact on the characterization of AML compared to MDS, which led the researchers to recommend integrating OGM into new prognostic scoring methods for both myeloid malignancies. In the study published in Blood Cancer Journal, researchers analyzed samples from 68 adult MDS and AML patients using OGM to evaluate OGM's performance in the detection of cytogenetic abnormalities that may impact diagnosis and stratification into groups for treatment. In 33% of MDS samples and 54% of AML samples, the study reported more clinically relevant variants were detected using OGM than were found by traditional cytogenetic methods and these variants were reported to be highly relevant to the understanding of pathogenesis of these disorders. Additional findings of the study: The R-IPSS score was changed for 6 cases, which could impact prognosis or assist in patient stratification. In 8 cases, OGM found clinically significant events. OGM also detected balanced structural variants identifying partner genes of driver genes not routinely identified by other techniques.
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EXLS | Hot Stocks08:07 EDT ExlService collaborates with CyberCube to develop cyber insurance solutions - EXL announced a collaboration with CyberCube to jointly develop cyber insurance solutions for the property and casualty, P&C, insurance industry. Leveraging EXL's insurance industry data, analytics and operations management expertise along with CyberCube's cyber risk signals, scores, and analytics, the solutions will help insurers scale their cyber insurance offerings to meet growing demand. Importantly, the combined offering will help standardize cyber risk underwriting by creating a single view of risk that can be applied consistently and tracked across the organization, creating a common framework across pricing, actuarial, reinsurance partners and the Chief Underwriting Officer. The partnership launch offering will center on underwriting optimization leveraging CyberCube's single-risk product Account Manager. "Cyber is a tough class of business and we are seeing an uptick in both frequency and severity of loss activity," said Raghav Maheshwari, Global Head of P&C Commercial Insurance and Insuretech at EXL. "The biggest challenge we see insurers facing in this space is the lack of continuity and consistency in the way cyber risk is measured, tracked and reported. By working together with CyberCube, we will create a proprietary view of cyber risk that standardizes how underwriters will evaluate and underwrite cyber risks, simplify the way underwriting teams can ingest data and assess cyber risks, and ultimately provide a support model for cyber underwriters."
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PLAY | Hot Stocks08:06 EDT Dave & Buster's to open 11 units across KSA, UAE, Egypt - Just a few months after announcing its international expansion plans Dave & Buster's inks its first multi-country, multi-unit deal. The Brand will begin its expansion with sites in the Kingdom of Saudi Arabia, followed by the United Arab Emirates and Egypt.
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SHO | Hot Stocks08:05 EDT Sunstone Hotel reports Q3 comparable hotels occupancy down 1450 point from 2019 - Sunstone Hotel Investors provided an update on recent operating trends. The Company's operations for July and August 2022 reflect continued strong rate growth and recovering occupancy levels. While leisure travel continues to be robust, the Company is seeing the greatest demand growth at its urban and group-oriented hotels which are experiencing higher lead volumes, an increase in near-term booking activity, better than expected attendance at group events and increased business transient demand. Occupancy for the comparable 13 hotels which include all hotels currently owned by the Company except Montage Healdsburg and Four Seasons Resort Napa Valley was down 1,450 basis points in Q3 QTD as compared to the same period in 2019. Excluding the Renaissance Washington DC, which is undergoing significant renovation work in advance of its conversion to the Westin Washington DC in 2023, Comparable Portfolio occupancy was down only 1,270 basis points as compared to the same period in 2019. Average Daily Rate for the Comparable Portfolio in Q3 2022 QTD was 16.9% higher than the same period in 2019 with nearly every hotel in the portfolio achieving higher rates than 2019. Excluding the Renaissance Washington DC, Comparable Portfolio ADR was 16.5% higher as compared to the same period in 2019. RevPAR for the Comparable Portfolio was down 2.7% in Q3 2022 QTD as compared to the same period in 2019. Excluding the Renaissance Washington DC, Comparable Portfolio RevPAR was down only 0.4% as compared to the same period in 2019. Group booking activity has increased in recent weeks with Comparable Portfolio group revenue pace for the second half of 2022 now down only 13% as compared to the same time in 2019. This represents an increase of nearly 200 basis points from June 2022. As of September 2022, the Comparable Portfolio has 86% of total transient room nights on-the-books for September to December 2022 as compared to the same period in 2019, with average rates approximately 27% higher than the same period in 2019.
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CRWD... | Hot Stocks08:05 EDT CrowdStrike Appoints Jennifer Johnson as CMO - CrowdStrike (CRWD) announced the appointment of Jennifer Johnson as the company's new chief marketing officer . Leveraging a 20-year track record in software marketing with expertise in cybersecurity and IT management, Johnson is a seasoned CMO who has earned a reputation as a bold storyteller well known for helping companies define and dominate market categories. She has run global marketing for leading cybersecurity and technology organizations including Tenable (TENB) and Amplitude (AMPL) - both of which she helped lead through successful public offerings - as well as Coverity (now Synopsys) and Tanium. Most recently, she served as CMO at Illumio, and previously served on the Illumio Board. Johnson also served as a partner at Andreessen Horowitz and a Category Designer in residence at Play Bigger, where she helped clients introduce radically different go-to-market approaches, hone their strategic positioning and disrupt existing markets. She currently serves on the Board of Immersive Labs.
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INSP | Hot Stocks08:04 EDT Inspire Medical announces updates from ISSS, AAO-HNSF meetings - Inspire Medical Systems announced key updates from the International Surgical Sleep Society, ISSS, and American Academy of Otolaryngology, AAO-HNSF, meetings which took place in Philadelphia. "We were excited to return to in-person conferences and highlight our recent innovative technology enhancements to the Inspire platform and share compelling clinical data further demonstrating the real-world efficacy of our treatment," said Tim Herbert, President and CEO. "Inspire is a proud partner and sponsor of ISSS, the world's preeminent organization dedicated to the surgical evaluation and treatment of patients with sleep disorders, and AAO-HNSF, one of the world's largest organizations representing specialists who treat the ear, nose, throat, and related structures of the head and neck." Posters and Presentations: "A Noninferiority Analysis of 3- versus 2- Incision Techniques for HNS Implantation." Safety and efficacy profile for 2-incision technique is noninferior to 3-incision technique. Operative time is significantly decreased with the 2-incision technique to 87 minutes. "Real-World Outcomes from Over 3 Million Nights of Upper Airway Stimulation Therapy for CPAP Intolerant Obstructive Sleep Apnea." First ever "big data" report of UAS outcomes; Usage trends demonstrate high compliance to UAS despite history of CPAP intolerance. "Outcomes of Surgical Upper Airway Stimulation in Hispanic vs Non-Hispanic Populations." Analysis demonstrated no difference in UAS outcomes in Hispanic patients versus non-Hispanic patients; The number of Hispanic participants in the ADHERE registry is just 2.1% of the overall participants, which is significantly lower than their proportion in the general U.S. population; This analysis highlights the need to understand barriers to care in receiving surgical UAS for patients of differing socioeconomic, ethnic, and educational backgrounds. "Long-term Generator Replacement in Hypoglossal Nerve Stimulator Clinical Trial Patients." Longest follow-up study of hypoglossal nerve stimulation; IPG replacements are safe and typically occur without complications; Outcomes at 9 years are consistent with 5-year results
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TMBR | Hot Stocks08:04 EDT Timber Pharmaceuticals receives positive COMP opinion for TMB-001 - Timber Pharmaceuticals announced that the Committee for Orphan Medicinal Products at the European Medicines Agency issued a positive opinion on the Company's application for orphan designation for TMB-001 for the treatment of autosomal recessive congenital ichthyosis. Based on the COMP's opinion, the European Commission is expected to issue its decision on the orphan designation in approximately 30 days.
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WSC | Hot Stocks08:03 EDT WillScot Mobile Mini acquires assets of portable storage provider - WillScot Mobile Mini Holdings announced it has acquired the dry rental storage fleet of Container Solutions based in Concord, California. The acquisition adds approximately 1,200 portable storage containers and mobile offices to the WillScot Mobile Mini fleet. Container Solutions is retaining its rental fleet of refrigerated and temperature-controlled containers, as well as its container sales and modifications business.
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CMCSA CMCSK | Hot Stocks08:03 EDT Comcast increases share repurchase authorization to $20B - Comcast announced that its board of directors has increased its share repurchase program authorization to a total of $20B, effective as of September 13. The authorization does not have an expiration date. To date during 2022, Comcast has repurchased $9B of its Class A common stock.
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TCON | Hot Stocks08:02 EDT Tracon Pharmaceuticals announces Fast Track designation for envafolimab - TRACON Pharmaceuticals announced that the U.S. Food and Drug Administration has granted fast track designation for the development of envafolimab for patients with locally advanced, unresectable or metastatic undifferentiated pleomorphic sarcoma and myxofibrosarcoma who have progressed on one or two prior lines of chemotherapy.
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CRNC | Hot Stocks08:02 EDT Cerence selected by CFMOTOT to bring coversational AI to two-wheelers, ATVs - Cerence announced that CFMOTO has selected Cerence for conversational AI-powered interaction with its two-wheelers and ATVs, marking a major strategic win for Cerence Ride, the company's conversational AI platform for two-wheelers. As two-wheeler ridership expands worldwide and as consumers turn to ATVs for safe, outdoor fun, CFMOTO's partnership with Cerence will transform the motorcycle and ATV experience, empowering its riders with the information they need - including two-wheeler-centric, voice-powered navigation; system controls and diagnostics via voice; and cloud-based content - in a safe manner while minimizing distractions. "The motorcycle and ATV experience has long been in need of enhancements that make riding safer and more delightful by using the same conversational AI that car owners have experienced for years," said Siva Subramanian, SVP, Connected AI & Mobility, Cerence. "We are proud to partner with CFMOTO as they transform the experience for their riders through AI-powered technologies that enhance their safety, comfort, and enjoyment."
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TRHC | Hot Stocks08:01 EDT Tabula Rasa HealthCare Co-President Brian Adams named interim CEO - Tabula Rasa HealthCare announced that co-founders Dr. Calvin Knowlton, BScPharm, MDiv, PhD, ScD, CEO and Board Chairman, and Dr. Orsula Knowlton, PharmD, MBA, Co-President and Chief Marketing and New Business Development Officer, will retire from TRHC and step down as members of the Board of Directors, effective immediately. Director Michael Purcell has been named Independent Chair of the Board. Brian Adams, TRHC's Co-President, will serve as interim CEO while the Board executes a comprehensive process to identify a permanent successor. To support a seamless transition, the Knowltons have signed consulting agreements with TRHC through the end of the year.
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CHH | Hot Stocks08:01 EDT Choice Hotels raises number of shares for repurchase program - Choice Hotels International announced that its board of directors has approved an increase in the number of shares authorized under its share repurchase program by five million shares. When added to the remaining number of available shares previously authorized for repurchase, this results in a total authorization of approximately 6.7 million shares.
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BKYI | Hot Stocks07:59 EDT Swivel Secure Europe deploys AuthControl Sentry to multinational conglomerate - BIO-key International announced that Swivel Secure Europe today deployed AuthControl Sentry to a Dutch-based multinational conglomerate in the furniture and home accessories market that will allow their suppliers to have secure SSO access to legacy enterprise applications.
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GPL | Hot Stocks07:50 EDT Great Panther Mining receives delisting notice from NYSE American - Great Panther Mining reports that it has a received a letter from the New York Stock Exchange notifying the company that as a result of the filing of a notice of intention to make a proposal under the Bankrupcy and Insolvency Act and in accordance with the NYSE American Company Guide, NYSE Regulation has determined that the company's common shares will be delisted from the NYSE American. The NYSE also notified the company that trading of the Shares has been halted as of September 13, 2022. The company has elected not to appeal NYSE Regulation's determination. A Form 25 will be filed with the SEC, which will remove the Shares from listing and registration on the NYSE. The company expects that its Shares will be eligible to be quoted on the OTC Pink operated by the OTC Markets Group if one or more brokers choose to make a market for the Shares. To the extent the Shares are quoted on the OTC Pink, the company expects such market may provide significantly less liquidity than the NYSE American, and trading prices of the Shares may decline. However, there can be no assurances regarding any such initial quotation, the existence of a market or trading prices. Due to the risks and uncertainties resulting from the BIA proceedings, trading in the company's Shares during the pendency of the BIA proceedings poses substantial risks.
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SPRC | Hot Stocks07:39 EDT SciSparc enters agreement to acquire Wellution for $20M - SciSparc announced the signing of a definitive agreement with Merhavit M.R.M Holding and Management, to acquire its rights to purchase, Wellution, an Amazon.com Marketplace account, American food supplements and cosmetics brand and trademark. The Company has established a new wholly owned subsidiary, SciSparc Nutraceuticals Inc., to hold the new assets. Wellution sells dozens of hemp-based products, including hemp gummies, hemp oil capsules, hemp gel, hemp cream, detox pills, height pills, antibacterial creams, and anti-aging creams, among other beauty and hair treatment products that are all manufactured in the United States. In addition to purchasing the Brand, SciSparc will enter a management agreement and received the option to expand the Brand to additional territories such as Europe, as well as a 12-month distribution agreement with a minimum initial order by the distributor of $100,000 of the Brand's products. The management agreement includes the fulfillment of Amazon's conditions, manufacturing, inventory and advertising management, storage and shipment to the Amazon warehouse and maintaining a pre-determined profit level for the products. The management services would be provided by a company for which SciSparc's CEO and SciSparc's chairman of the board serve as directors. The distribution agreement would provide for the marketing and commercialization of the Brand's products, through offline channels in the United States.Upon closing, which is subject to certain conditions and expected to be completed within the next 30 days, SciSparc will pay a base cash payment of $4.59M and in 12 months pay an additional deferred cash payment of a multiple 3 times the amount by which the acquired Brand EBITDA exceeds $1.12M. In addition, the Company will grant to M.R.M $15M worth of warrants to purchase ordinary shares of SciSparc at an exercise price of $7.00 per share and with an exercise period of five years from the closing of the transaction. The Warrants will become exercisable upon the achievement of a milestone of $100M of sales of the Brand in the aggregate or if the price of SciSparc's ordinary shares closes at $10.00 or above.
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EMWP | Hot Stocks07:38 EDT Eros Media World files appeal with NYSE staff on delisting determination - Eros Media World has announced that it has duly filed an appeal with the New York Stock Exchange to review the determination made by the NYSE Regulation to commence proceedings to delist the Company's A ordinary shares and suspend trading immediately . The Company's request for a review of the Staff Determination by a committee of the Board of Directors of the NYSE is in accordance with Section 804.00 of the NYSE's Listed Company Manual. The company's request has been acknowledged by the NYSE last week in a letter, further confirming December 15 as scheduled date of review.
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BWAY CI | Hot Stocks07:35 EDT Brainsway announces Cigna to cover treatment of OCD with TMS - BrainsWay (BWAY) announced that Cigna Corporation (CI) has announced positive coverage applicable to Deep Transcranial Magnetic Stimulation, TMS, for the treatment of obsessive-compulsive disorder, OCD. With this new policy added, over a total of 86M adults now having access to BrainsWay's pioneering Deep TMS OCD treatment. "The establishment of this positive coverage for OCD further facilitates BrainsWay's ability to capitalize on its leadership role in advancing treatment of this debilitating condition," said Christopher von Jako, PhD, President and Chief Executive Officer of BrainsWay. "More importantly, the continued reimbursement momentum for Deep TMS is resulting in increased access of our unique therapy that is critical to our mission of improving the health and transforming the lives of those suffering from disorders with limited treatment options." Cigna will be issuing an updated revision to its TMS medical coverage policy effective September 15, 2022 extending coverage to patients aged 18 and older diagnosed with OCD. Under the revised policy, an initial 30-36 TMS treatment session regimen will be classified as medically necessary after a failure of two or more medication trials and a trial of evidence-based psychotherapy without significant improvement in symptoms. Patients with 30% or greater improvement in their Yale-Brown Obsessive Compulsive Scale maintained for at least two months would also be candidates for an additional regimen of 30-36 sessions.
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AVRO | Hot Stocks07:34 EDT Avrobio announces approval of Hunter syndrome CTA - Avrobio announced that the U.K. Medicines and Healthcare Products Regulatory Agency, or MHRA, Research Ethics Committee, or REC, and Health Research Authority, or HRA, have approved the clinical trial application, or CTA, submitted by Avrobio's collaborators at the University of Manchester, U.K. for initiation of the Phase 1/2 clinical trial of investigational autologous hematopoietic stem cell, or HSC, gene therapy in infants diagnosed with neuronopathic mucopolysaccharidosis type II, or nMPS-II, or Hunter syndrome. This rare and seriously debilitating lysosomal disorder primarily affects young males. UoM's 24-month, non-randomized, open label study will enroll up to five children aged three months and 12 months diagnosed with nMPS-II to evaluate the safety and tolerability, pharmacodynamic and clinical efficacy of HSC gene therapy. The gene therapy, which Avrobio refers to as AVR-RD-05, is designed to transduce autologous HSCs ex vivo with a lentiviral vector encoding a brain-targeted iduronate-2-sulfatase enzyme, which is deficient in these patients. UoM expects to dose the first patient in the trial in 1H 2023. In these mouse models of Hunter syndrome, brain-targeted HSC gene therapy showed improvement across multiple metrics, including normalization of skeletal features such as the cheekbone dimensions, the width of the humerus and femur bones, correction of neurons in the brain and the preservation of higher brain functions including working memory.
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RVLGF | Hot Stocks07:33 EDT Revival Gold completes acquisition of Ace Mineral Claims - Revival Gold completed the acquisition of the ACE Mineral Claims which are located within the Beartrack-Arnett Gold Project located in Lemhi County, Idaho, USA. On September 12th, 2022, the Company paid the remaining $500,000 option payment under the Bull Run Agreement fulfilling all requirements to acquire a 100% interest in the ACE Claims consisting of 68 unpatented mineral claims totaling approximately 571 hectares. The ACE Claims border the known Mineral Resources at Beartrack-Arnett and host several additional prospective gold exploration targets.
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NUE | Hot Stocks07:33 EDT Nucor drops 5% to $129.40 after Q3 EPS guidance misses estimates
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SURF | Hot Stocks07:32 EDT Surface Oncology to present preclinical data on IL-27 - Surface Oncology announced that the company will present new preclinical data on the role of IL-27 in therapy resistance at the 10th Annual Cytokines Meeting of the International Cytokine and Interferon Society, ICIS, being held September 20 - 23 at Big Island, Hawaii. The poster, entitled IL-27 Inhibits Immune Cell Reinvigoration Mediated by PD-1 Blockade and Induces a Type 1 Interferon Gene Expression Signature Associated with Resistance to Therapy in Cancer Patients. Summary of key data: IL-27 induces the expression of several immunoregulatory receptors and reduces inflammatory cytokine production; An IFN-stimulated gene signature is expressed in a variety of human tumors and associated with resistance to cancer therapies including chemotherapy, radiotherapy, and immune checkpoint inhibition; IL-27 and Type 1 interferons counteract the immune cell reinvigoration seen after PD-(L)1 pathway blockade in human PBMCs, while IFNgamma does not. Loss of IL-27 function, through either genetic deficiency or pharmacologic inhibition by SRF388, a first-in-class anti-IL-27 monoclonal antibody, leads to tumor growth inhibition in mouse models and early clinical data have shown monotherapy activity of SRF388 in patients with cancer.
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MNMD | Hot Stocks07:31 EDT Mind Medicine regains compliance with NASDAQ listing requirements - Mind Medicine announced that it has received a letter from The Nasdaq Stock Market advising the Company that it has regained compliance with Nasdaq's minimum bid price listing requirement. The Company has satisfied the terms for continued listing on the Nasdaq Capital Market by complying with the minimum bid price requirement of $1.00 per share under Nasdaq Listing Rule 5550, and all other criteria for continued listing. Accordingly, Nasdaq has advised that the matter is now closed.
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GOOG... | Hot Stocks07:31 EDT Google, Meta fined over $70M for privacy violations in South Korea - South Korea's Personal Information Protection Commission has fined Google (GOOGL) $50M and Meta (META) $22M for privacy violations, the PIPC said in a statement. The data watchdog claims neither Google nor Meta properly obtain consent or inform users on how they collect and use data, particularly with regards to behavioral information used to predict interests for marketing and advertising purposes. "Third-party behavioral information is obtained when users visit websites and apps other than the platform. Since it is automatically collected, it is difficult to predict which behavior performed on which website or app is collected," said the PPIC. Reference Link
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LRMR | Hot Stocks07:18 EDT Larimar Therapeutics announces $70M underwritten offering - Larimar Therapeutics announced the pricing of an underwritten offering of 22,225,000 shares of common stock. The shares are being sold at an offering price of $3.15 per share, which is equal to the closing price on Nasdaq for Larimar's common stock on September 13, 2022. The gross proceeds to Larimar, before deducting the underwriting discounts and commissions and estimated offering expenses, are expected to be approximately $70.0 million. The offering is expected to close on or about September 16, 2022, subject to customary closing conditions. Larimar has granted the underwriters a 30-day overallotment option to purchase up to 3,333,750 additional shares of common stock at the offering price, less underwriting discounts and commissions. Deerfield Management and other notable life science investors participated in the offering. Guggenheim Securities, LLC is acting as lead book-running manager for the offering and William Blair & Company, L.L.C. is also acting as a book-runner for the offering. LifeSci Capital LLC and JMP Securities, a Citizens Company, are acting as co-managers for the offering. Larimar intends to use the net proceeds from the offering to support the clinical development of CTI-1601, and for working capital and general corporate purposes, including research and development expenses.
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ASLN | Hot Stocks07:17 EDT Aslan Pharmaceuticals commences clinical program of eblasakimab in AD - ASLAN Pharmaceuticals plans to initiate a new clinical trial of eblasakimab for the treatment of moderate-to-severe atopic dermatitis in adult patients who have previously been treated with dupilumab. Eblasakimab is a potential first-in-class monoclonal antibody targeting the IL-13 receptor that has the potential to deliver a differentiated efficacy and safety profile. ASLAN expects to enroll the first patient in the trial in the fourth quarter of 2022. The TREK-DX trial is expected to enroll 75 patients in a randomized, double-blind, placebo-controlled, multicenter trial in North America to evaluate the efficacy and safety of eblasakimab in patients with moderate-to-severe AD previously treated with dupilumab. The trial will enroll patients who have discontinued dupilumab treatment for any reason, including inadequate control of AD, loss of access or an adverse event. The program is part of the Company's existing operating plan and has no impact on its previously-reported cash runway. The trial will consist of a 16-week treatment period and a 12-week safety follow-up period. The primary efficacy endpoint is percentage change in Eczema Area Severity Index score from baseline to week 16. Key secondary efficacy endpoints include the proportion of patients achieving Investigator Global Assessment score of 0 or 1, proportion of patients with a 75% or greater reduction in EASI, proportion of patients achieving EASI-50 and EASI-90, and changes in peak pruritus. ASLAN is also conducting the TREK-AD trial, a global randomized, double-blind, placebo-controlled, dose-ranging, Phase 2b clinical trial, to evaluate the efficacy and safety of eblasakimab in adult patients with moderate-to-severe AD who are candidates for systemic therapy. Topline data from this trial is expected in the first half of 2023.
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SRPT | Hot Stocks07:16 EDT Sarepta prices $1B of convertible senior notes due 2027 - Sarepta Therapeutics announced the pricing of $980M aggregate principal amount of convertible senior unsecured notes that will mature on September 15, 2027, unless earlier redeemed, repurchased or converted. The notes are being offered and sold only to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended. Sarepta has also granted the initial purchasers of the notes an option to purchase up to an additional $150M aggregate principal amount of notes. The sale of the notes to the initial purchasers is expected to settle on September 16, 2022, subject to customary closing conditions. An entity affiliated with a member of Sarepta's Board of Directors has agreed to purchase $20M aggregate principal amount of the notes in a separate concurrent private placement under Section 4(a)(2) of the Act. The offering of the notes in the Rule 144A offering is not conditioned upon the closing of the concurrent private placement, but the concurrent private placement is conditioned upon the closing of the Rule 144A offering. Sarepta estimates that the net proceeds of the offerings will be approximately $979.4M after deducting the initial purchasers' discounts and commissions and estimated offering expenses payable by Sarepta. Sarepta intends to use $110.7M of the net proceeds from the offerings to pay the cost of the capped call transactions, and approximately $248.3M to repurchase approximately $150.6M in aggregate principal amount of its 1.50% Convertible Senior Notes due 2024, inclusive of any applicable premium and accrued interest. In addition, Sarepta intends to use approximately $585.5M of the net proceeds from the offerings to repay borrowings under, to pay accrued and unpaid interest and prepayment fees under, and terminate its credit agreement and the remaining net proceeds to fund general corporate purposes. Sarepta anticipates that, along with current cash and projected revenue, this offering is sufficient to fund operations to profitability.
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APGOF | Hot Stocks07:14 EDT Apollo Silver reports assay results from drill program at Calico Silver Project - Apollo Silver reports assay results from a surficial rock grab sampling program and remaining assays from the Phase 1 2022 Drill Program at the Calico Silver Project located in San Bernardino County, California. The surficial rock grab sampling and drilling programs are part of the 2022 Calico Technical Program, which aims to upgrade and expand the previously announced Inferred Mineral Resource Estimate of 166 million ounces of silver contained in 58.1 million tonnes at an average grade of 89 grams per tonne. "These results have confirmed the significant gold potential at Calico" commented Apollo CEO Tom Peregoodoff. "The surficial sampling combined with Apollo's drilling have defined an extensive gold horizon that has never been fully delineated by previous operators... With drilling set to commence this month, we are on track to deliver a revised resource estimate in early 2023 and will commence engineering studies shortly thereafter."
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OSUR | Hot Stocks07:12 EDT OraSure collaborates with Mars Petcare to better understand pet health - OraSure Technologies announced a new collaboration between Diversigen, a subsidiary of OraSure Technologies, and Mars Petcare, which will help researchers better understand pet health. As part of the MARS PETCARE BIOBANK project, Diversigen will sequence microbiome samples from cats and dogs of all breeds and breed makeups in efforts to improve pet care. "This collaboration will utilize Diversigen's specialized metagenomics service that uses curated databases to improve sample analysis," said Kathleen Weber, President of Molecular Solutions for OraSure Technologies. "Our team of expert scientists and bioinformaticians will help researchers involved in the project improve the understanding of canine and feline microbial community composition and function." Samples collected as part of the biobank study will be analyzed and Diversigen will sequence the DNA of the microorganisms in the sample.
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QK | Hot Stocks07:10 EDT Q&K International announces results of annual meeting - Q&K International Group announced the results of its 2022 annual general meeting held in Shanghai on September 13, 2022. Specifically, the shareholders have approved: the change of the Company's name from "Q&K INTERNATIONAL GROUP LIMITED" to "FLJ Group Limited"; and the amendment to the Company's amended and restated memorandum and articles of association of the Company to reflect the change in Company's name. Accordingly, the Company has changed its corporate name from "Q&K International Group Limited" to "FLJ Group Limited", effective on September 13, 2022. In addition, the Company expects to begin trading under the new ticker symbol "FLJ" on the NASDAQ effective on or about September 26, 2022.
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AREB | Hot Stocks07:10 EDT American Rebel signs LOI with Sierra E-Life, to enter E-Bike business - American Rebel announces signing a letter of intent, LOI, with Sierra E-Life, a full-service USA manufacturer of E-Bikes. "We are very excited to diversify our product offerings, thereby enhancing American Rebel as a lifestyle brand, by entering the futuristic, technology-savvy market of E-Bikes," said American Rebel CEO Andy Ross. "We think the E-Bike market is ready for the E-Bike with an attitude! American Rebel's grit, style and patriotic appeal will carry through to every product we design and put the American Rebel name on." American Rebel, in collaboration with Sierra E-Life, has designed three distinct E-Bike models: the Patriot 500, the Freedom 750 and the Rebel 1000. The Patriot 500, the Freedom 750 and the Rebel 1000 are projected to be Made in the USA with global components.
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OXBDF | Hot Stocks07:09 EDT Oxford Biomedica enters agreement with biotech company for The Full Solution - Oxford Biomedica Solutions announced that it has signed an agreement with an undisclosed US-based private biotechnology company. The agreement will provide The Full Solution from construct design to process development to IND support, including a proven platform for multiple constructs supporting its new partner's gene therapy programs.
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AREB | Hot Stocks07:08 EDT American Rebel signs LOI with Deerfield, to enter E-Bike business - American Rebel announces signing a letter of intent, LOI, with Deerfield, Florida based Sierra E-Life, a full-service USA manufacturer of E-Bikes. "We are very excited to diversify our product offerings, thereby enhancing American Rebel as a lifestyle brand, by entering the futuristic, technology-savvy market of E-Bikes," said American Rebel CEO Andy Ross. "We think the E-Bike market is ready for the E-Bike with an attitude! American Rebel's grit, style and patriotic appeal will carry through to every product we design and put the American Rebel name on." American Rebel, in collaboration with Sierra E-Life, has designed three distinct E-Bike models: the Patriot 500, the Freedom 750 and the Rebel 1000. The Patriot 500, the Freedom 750 and the Rebel 1000 are projected to be Made in the USA with global components.
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EEX | Hot Stocks07:08 EDT Emerald Holding gets final proceeds relating to insurance litigation settlement - Emerald Holding announced that it has received proceeds totaling $149.25M related to its previously announced insurance litigation settlement for canceled events under the Company's 2020 and 2021 event cancellation insurance policies. Of the $149.25M, $148.54M is expected to be recognized as Other Income, net for the third quarter of 2022. In total, Emerald has submitted insurance claims under its 2020 and 2021 event cancellation insurance policies of approximately $348.4M, which represents the net amount of expected gross revenues less avoided costs for cancelled events scheduled to take place during 2020 and 2021. Including the $149.25M litigation settlement payment, Emerald has received total proceeds under the 2020 and 2021 event cancellation insurance policies of $372.9M. Herve Sedky, Emerald's CEO commented, "We are pleased to have received the final proceeds relating to the settlement of our insurance litigation. The incremental cash not only helps further improve our already strong liquidity position but also allows us to focus all of our attention on building our business moving forward."
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ALT | Hot Stocks07:07 EDT Altimmune announces results from Phase 1b study of pemvidutide - Altimmune announced "positive" topline results from its 12-week Phase 1b study of pemvidutide in subjects with non-alcoholic fatty liver disease. NAFLD. The trial was a randomized, double-blind, placebo-controlled study, with Dr. Stephen A. Harrison, Medical Director, Pinnacle Research, serving as the Principal Investigator. The primary efficacy endpoint was the percent reduction in liver fat content from baseline, and the key secondary efficacy endpoint was the % weight loss from baseline, both at 12 weeks of treatment. The trial was conducted without adjunctive diet and exercise interventions that are the standard for obesity trials. Ninety-four subjects were randomized and treated at 13 sites across the U.S. Mean BMI at baseline was approximately 36 kg/m2 and mean liver fat content, as measured by MRI-PDFF, was approximately 22%. Twenty-seven subjects had type 2 diabetes at baseline, and approximately 75% of study subjects were of Hispanic ethnicity. The trial met its primary endpoint in all pemvidutide treatment groups. At the 1.8 mg dos, pemvidutide achieved a mean reduction of liver fat content of 68.5%, with 94.4% of subjects achieving a 30% reduction in liver fat, 72.2% achieving a 50% reduction in liver fat, and 55.6% of subjects achieving normalization of liver fat, defined as liver fat fraction of 5% or less. In addition, mean serum alanine aminotransferase levels declined in all subjects, and in subjects with baseline serum ALT above 30 IU/L, levels declined more than 17 IU/L at all dose levels and 27.0 IU/L in the 2.4 mg dose cohort. The trial also met its key secondary endpoint in all pemvidutide treatment groups. Employing an efficacy estimand, mean weight losses of 4.9% in subjects without diabetes and 4.4% in subjects with diabetes were achieved at the 1.8 and 2.4 mg doses, respectively. Pemvidutide was reported to be generally well tolerated. Gastrointestinal events comprised the majority of the adverse events. Even without dose titration, the symptoms experienced by subjects were predominantly mild and transient in nature, consistent with known GLP-1 class effects. "We are pleased with the results of this trial, including the extent of liver fat and serum ALT reductions. Weight loss was within our target range, and good tolerability was observed without the need for dose titration. In addition, no clinically significant ALT elevations were observed," said Vipin Garg,, President and Chief Executive Officer of Altimmune. "With these positive results in hand, we look forward to reporting data from the 24-week NAFLD trial, as well as 24-week interim data from our MOMENTUM obesity trial."
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XPO JEF | Hot Stocks07:07 EDT XPO Logistics appoints Weisfield as Chief Strategy Officer for RXO spin-off - XPO Logistics (XPO) announced that Jared Weisfeld will become chief strategy officer of RXO, the planned spin-off of XPO's brokered transportation platform. Weisfeld has been appointed chief strategy officer for XPO's North American transportation division, effective immediately. He will be responsible for RXO's strategy and analysis of growth opportunities when the spin-off is complete, and will oversee RXO's engagement with the investment community. He reports to Drew Wilkerson, who, as previously announced, will be chief executive officer of RXO, and currently serves as president, transportation - North America. Weisfeld was most recently with Jefferies Financial Group (JEF).
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AKTS | Hot Stocks07:05 EDT Akoustis receives development order for XBAW 5G mobile filter solution - Akoustis Technologies announced that it has received an order for the development of a new 5G mobile XBAW filter for a tier-1 RF module maker. Akoustis received a purchase order from this customer in December of 2021 for delivery of resonator models to be used in the design of the new 5G mobile filter, with first sample delivery expected in the second half of calendar 2022 and production-ready filters expected by the end of calendar 2023, in-line with Akoustis' planned capacity expansion. The customer is a tier-1 RF module maker that is leveraging Akoustis' leading XBAW filter technology to address a difficult coexistence frequency band in 5G mobile. Akoustis expects that this customer will develop additional 5G mobile filters upon the successful completion of this initial design.
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PM | Hot Stocks07:05 EDT Philip Morris appoints Badrul Chowdhury as chief life sciences officer - Philip Morris announced that it has appointed a former FDA official to a position to accelerate its science-based transformation. Badrul Chowdhury is appointed PMI's chief life sciences officer, smoke-free products, succeeding Jorge Insuasty, who will complete his move into the recently created position of president, Vectura Fertin Pharma. After a short transition period, Badrul will join PMI's senior management team in January 2023, reporting to Jacek Olczak, CEO.
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ONDS | Hot Stocks07:05 EDT Ondas gets Canadian approval to sell 900 MHz ATCS platform - Ondas Holdings Ondas Networks and American Robotics , announced that Ondas Networks has received authorization from the Canadian government to sell its 900 MHz Advanced Train Control System platform. The ATCS platform, which had previously been introduced to the U.S. market, is now available for deployment throughout the Canadian rail system. The products will be sold and marketed by Siemens Mobility under their Airlink brand name to both Canadian freight and transit rail customers.
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ALT | Hot Stocks07:05 EDT Altimmune announces results from Phase 1b study of pemvidutide - Altimmune announced "positive" topline results from its 12-week Phase 1b study of pemvidutide in subjects with non-alcoholic fatty liver disease. NAFLD. The trial was a randomized, double-blind, placebo-controlled study, with Dr. Stephen A. Harrison, Medical Director, Pinnacle Research, serving as the Principal Investigator. The primary efficacy endpoint was the percent reduction in liver fat content from baseline, and the key secondary efficacy endpoint was the % weight loss from baseline, both at 12 weeks of treatment. The trial was conducted without adjunctive diet and exercise interventions that are the standard for obesity trials. Ninety-four subjects were randomized and treated at 13 sites across the U.S. Mean BMI at baseline was approximately 36 kg/m2 and mean liver fat content, as measured by MRI-PDFF, was approximately 22%. Twenty-seven subjects had type 2 diabetes at baseline, and approximately 75% of study subjects were of Hispanic ethnicity. The trial met its primary endpoint in all pemvidutide treatment groups. At the 1.8 mg dos, pemvidutide achieved a mean reduction of liver fat content of 68.5%, with 94.4% of subjects achieving a 30% reduction in liver fat, 72.2% achieving a 50% reduction in liver fat, and 55.6% of subjects achieving normalization of liver fat, defined as liver fat fraction of 5% or less. In addition, mean serum alanine aminotransferase levels declined in all subjects, and in subjects with baseline serum ALT above 30 IU/L, levels declined more than 17 IU/L at all dose levels and 27.0 IU/L in the 2.4 mg dose cohort. The trial also met its key secondary endpoint in all pemvidutide treatment groups. Employing an efficacy estimand, mean weight losses of 4.9% in subjects without diabetes and 4.4% in subjects with diabetes were achieved at the 1.8 and 2.4 mg doses, respectively. Pemvidutide was reported to be generally well tolerated. Gastrointestinal events comprised the majority of the adverse events. Even without dose titration, the symptoms experienced by subjects were predominantly mild and transient in nature, consistent with known GLP-1 class effects. "We are pleased with the results of this trial, including the extent of liver fat and serum ALT reductions. Weight loss was within our target range, and good tolerability was observed without the need for dose titration. In addition, no clinically significant ALT elevations were observed," said Vipin Garg,, President and Chief Executive Officer of Altimmune. "With these positive results in hand, we look forward to reporting data from the 24-week NAFLD trial, as well as 24-week interim data from our MOMENTUM obesity trial."
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GSMG | Hot Stocks07:04 EDT Glory Star New Media launches CheerReal NFT application - Glory Star New Media Group Holdings announced that on September 9 it has officially launched CheerReal, a self-developed brand-new digital collection non-fungible tokens, or NFT, application, in both iOS and Android. Users can download CheerReal either from iOS or Android App Stores to get access to the digital arts on their mobile devices.
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LRMR | Hot Stocks07:04 EDT Larimar announces FDA clearance for 25 mg cohort of Phase 2 CTI-1601 trial - Larimar Therapeutics announced that the U.S. Food and Drug Administration has cleared the initiation of the 25 mg cohort of a Phase 2, four-week, placebo-controlled, dose exploration trial of CTI-1601 in Friedreich's ataxia patients. In a written communication to Larimar, the FDA indicated it was lifting its full clinical hold on the CTI-1601 program and imposing a partial hold. The design of the upcoming Phase 2 trial is identical to the design proposed by Larimar, with the exception of a requirement for the FDA to review data from the 25 mg cohort prior to escalating the dose in the second cohort. Larimar expects to begin the Phase 2 trial in Q4 2022, with top-line data expected in 2H 2023. The CTI-1601 program was placed on a clinical hold by the FDA following the Company's notification to the agency of 3 mortalities out of a total of 34 animals in a 26-week non-human primate (NHP) toxicology study designed to support extended dosing of patients with CTI-1601. All 3 of these NHPs were in the study's two highest dose groups and all NHPs in the two lower dose groups survived to the end of the study. The FDA's decision to allow the upcoming CTI-1601 Phase 2 trial to proceed follows Larimar's submission of a complete response with detailed analyses from Larimar's NHP toxicology studies and Phase 1 clinical trials. Larimar's upcoming Phase 2 trial is designed to further characterize CTI-1601's safety, pharmacodynamic, and pharmacokinetic profiles to provide information about the preferred long-term dose and dose regimen. Eligible patients will include ambulatory and non-ambulatory individuals with FA who are at least 18 years old. Patients may be CTI-1601 treatment naive or have previously participated in Larimar's Phase 1 single- or multiple ascending dose trials. Patients enrolled into the Phase 2 trial will be randomized 2:1 to receive CTI-1601 or placebo. The trial is designed to enroll approximately 24 - 30 total patients across two cohorts, with the first cohort of 12 - 15 patients evaluating a 25 mg dose of CTI-1601. Patients will receive CTI-1601 or placebo daily via subcutaneous injections for the first 14 days, and then every other day until day 28. Key endpoints will include safety assessments, measures of frataxin levels and other PD markers in peripheral tissues, as well as PK assessments. Dose escalation to 50 mg in the second cohort will be contingent on the FDA's agreement based on its review of the data from the trial's first cohort, and on the review by the trial's independent data monitoring committee. Previously completed Phase 1 single- and multiple-ascending dose clinical trials evaluated the safety, PK, and PD profiles of CTI-1601 administered subcutaneously at doses up to 100 mg daily for up to 13 days. No serious adverse events, important medical events, or treatment-related severe adverse events were reported in the trials. The most common adverse events were mild and moderate injection site reactions, which all resolved without intervention. Except for injection site reactions, the number and severity of adverse events did not increase with increasing exposure to CTI-1601. Data from cohorts 2 and 3 of the MAD trial also showed that subcutaneous injections of 50 or 100 mg of CTI-1601, administered daily for at least seven days, resulted in frataxin levels in buccal cells that were at or in excess of those that would be expected in phenotypically normal heterozygous carriers. Cohort 1 of the MAD trial, which evaluated a 25 mg dose, explored a daily dosing regimen for only four days. In contrast, the 25 mg cohort of the upcoming Phase 2 trial will explore 14 days of daily dosing followed by 14 days of every-other-day dosing.
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DOW | Hot Stocks07:03 EDT Dow an Mura plan to construct new facility at Bohlen - Dow and Mura Technology announce the next step in their ongoing collaboration to help solve the global plastics waste issue and advance circularity. Mura plans to construct a new facility at Dow's Bohlen site in Germany - the latest in a series of planned facilities across the U.S. and Europe to rapidly scale advanced recycling of plastics - and the first expected to be based at a Dow site. This project is targeted for a final investment decision by the end of 2023. Mura's new Bohlen facility in Germany, which is expected to be operational by 2025, would deliver approximately 120 kilotons per annum, or KTA, of advanced recycling capacity at full run-rate. This and the other planned units expected to be constructed across Europe and the U.S. would collectively add as much as 600KTA of advanced recycling capacity by 2030 - and position Dow to become the largest consumer of circular feedstock for polyethylene production globally. Dow aims to take advantage of co-location benefits, which could significantly reduce the cost of scaling advance recycling facilities. In addition, co-location of Mura's facilities at Dow locations would be expected to reduce carbon emissions by minimizing transportation of the offtake and as gas output from the advanced recycling process can be converted back to plastics, thereby ensuring no by-products go to waste.
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BCDA | Hot Stocks07:02 EDT BioCardia announces new data from CardiAMP Cell Therapey trial - BioCardia announces that new data from its CardiAMP Cell Therapy for Heart Failure pivotal trial, will be presented at the Heart Failure Society of America, HFSA, Annual Meeting on October 1, 2022 at 6:00pm titled, "Autologous Cell Therapy For HFrEF: Efficacy Outcomes at Two Years for The Roll-in Cohort of a Phase III Pivotal Trial." This year's HFSA meeting provides a hybrid format; in-person at the Gaylord National Harbor in Washington, D.C., or global live on-line access. This data from the CardiAMP Cell Therapy Heart Failure trial will be released Monday, October 3, 2022, with anticipated details for a conference call with trial clinical leadership and management to follow. "We look forward to presenting the two-year roll-in cohort results from the CardiAMP Cell Therapy for Heart Failure Trial at this year's HFSA annual meeting," stated BioCardia's Vice President of Clinical, Debby Holmes-Higgin. "In addition, we look forward to detailing efforts towards the implementation of the adaptive statistical analysis plan, which may further reduce trial risk and enable the DSMB to review the data early for efficacy."
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CMP | Hot Stocks06:49 EDT Compass Minerals to receive $252M investment from Koch Minerals & Trading - Compass Minerals announced that Koch Minerals & Trading, a subsidiary of Koch Industries, has agreed to make a $252M investment in Compass Minerals through the purchase of Compass Minerals common stock to support phase-one development of its previously identified 2.4 mMT lithium carbonate equivalent Great Salt Lake resource and debt reduction. Approximately $200M of the proceeds from the investment are expected to be used to advance the first phase of the company's sustainable lithium development project. This figure represents approximately 75% of total phase-one funding needs, according to the company's FEL-1 level project cost estimates. Compass Minerals expects the project's annual commercial production capacity to ultimately be approximately 35 kMT LCE, with an initial phase-one capacity of approximately 11 kMT LCE coming online by 2025. As part of the agreement, the companies will also explore value creation opportunities across Compass Minerals' broader operational platform by leveraging the expansive capabilities of KII's many operating subsidiaries, including in the areas of supply and procurement of fuel and raw materials, freight and logistics synergies, and project engineering and development support. Compass Minerals expects to use the remaining $52M of proceeds from the KM&T investment, less transaction expenses, to reduce debt, representing a significant step toward aligning the company's capital structure with its corporate growth strategy. Under the terms of the investment agreement, KM&T has agreed to purchase 6,830,700 shares of Compass Minerals common stock at a price of $36.87 per share, resulting in proceeds to Compass Minerals of $252M. The issuance price represents a 6.2% discount to the closing price and an 8.0% discount to the 5-day volume weighted average price as of Sept. 13. After the transaction closes, KM&T will own approximately 17% of Compass Minerals' outstanding shares of common stock and will have the ability to appoint two additional members to the Compass Minerals board of directors. Perella Weinberg Partners LP acted as sole financial advisor to Compass Minerals in the transaction and Cleary Gottlieb Steen & Hamilton acted as the company's legal advisor. Jones Day acted as legal advisor for KM&T.
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PFE | Hot Stocks06:46 EDT Pfizer begins Phase 3 study of mRNA-based influenza vaccine - Pfizer announced that the first participants have been dosed in a pivotal Phase 3 clinical trial to evaluate the efficacy, safety, tolerability and immunogenicity of the company's quadrivalent modified RNA influenza vaccine candidate in approximately 25,000 healthy U.S. adults.
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TRMB | Hot Stocks06:38 EDT Trimble acquires B2W Software, terms undisclosed - Trimble announced it has acquired privately-held B2W Software, a provider of estimating and operations solutions for the heavy civil construction industry. Financial terms were not disclosed. With the passage of the Infrastructure Investment and Jobs Act, or IIJA, and other infrastructure legislation across the globe, construction organizations are fast tracking the digitization of their processes and operations. As infrastructure projects become increasingly complex, data-driven insights and analytics will be imperative to improve productivity, increase efficiency and drive sustainability. B2W will be reported as part of the Buildings and Infrastructure segment.
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PRMW | Hot Stocks06:36 EDT Primo Water acquires Eureau Sources and Defeaus, terms undisclosed - Primo Water announced that Primo Water Europe has acquired Eureau Sources and Defeaus, two French companies specializing in the marketing and packaging of spring water. Eureau Sources, founded in 1996, specializes in packaging spring water in five-gallon returnable bottles for refrigerated water coolers. In 2016, the company became the French leader in bottling water in carafes. Eureau Sources draws water from four sources in the Cantal, Indre et Loire, Oise, and Vaucluse regions to effectively cover the entire French territory. Defeaus was founded in 1996 and has been marketing Hermes spring water since 2015. Located in Hautes-de-France, in the heart of the Oise, the water is bottled on-premise and distributed mainly in the Ile de France region to commercial and residential customers.
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LEU | Hot Stocks06:35 EDT Centrus Energy secures new nuclear fuel sales contracts worth $320M - Centrus Energy announced that it has secured new nuclear fuel sales contracts and commitments with an estimated value of approximately $320M in the last 12 months -- including approximately $270M year-to-date. Most of Centrus' revenues come from multi-year contracts with major utilities, often signed years in advance. The new sales commitments cover deliveries from 2022 to 2030, with the revenue and cost of sales to be booked in the quarter and year of delivery.
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NILE... | Hot Stocks06:33 EDT BitNile reports 60.45 BTC mined in August - BitNile Holdings published an unaudited update on Bitcoin production and miner installation. The number of miners and production capacity metrics within this press release represent the S19j Pro and S19 XP Antminers at the Michigan data center and the Texas facility hosted by Compute North. BitNile's BTC mining production is currently operating at an estimated annualized run rate of 787 Bitcoin based on market conditions as of September 9 including a mining difficulty of 32.05T. Mining and Operation Highlights as of September 9, 2022 were as follows: 60.45 BTC mined in August; 700 of the new S19 XP Antminers have been brought online; Miners in possession increased to 12,669 inclusive of 600 in the hands of our carrier, which once installed, will generate a combined processing power of approximately 1.091 exahashes per second, the computational power that is being used to mine Bitcoin; 393.6 total BTC mined to date; and 3,920 miners have been installed in racks in the new hosted facility in Texas, and BitNile anticipates having 6,500 miners there online by October 1.
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JNJ | Hot Stocks06:30 EDT Johnson & Johnson announces $5B share repurchase program - Johnson & Johnson announced that the Board of Directors has authorized the repurchase of up to $5B of the company's common stock.
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DWIN | Hot Stocks06:07 EDT Delwinds enters into Forward Share Purchase Agreement with Meteora - Delwinds Insurance Acquisition announced that it has entered into a Forward Share Purchase Agreement with Meteora Capital Partners or its affiliates pursuant to which Meteora has committed to owning, as of the date of consummation of DWIN's previously announced business combination with FOXO Technologies, a certain number of shares of DWIN Class A common stock, and may purchase up to an additional number of Public Shares from other holders of Public Shares, which shares in the aggregate may be up to a maximum of 3,000,000 shares. The Meteora Shares are subject to an agreement between the Company and Meteora in effect for a period of up to fifteen months after the BC Closing Date. Pursuant to such arrangement, Meteora has the right to sell the Meteora Shares in the open market and, at the end of the term of the Meteora agreement, or upon an accelerated maturity date, to require the Combined Company to purchase any Meteora Shares held by Meteora as of the fifteen month anniversary of the BC Closing Date at a price equal to the redemption price per Public Share at the Closing of the Business Combination. Additionally, concurrent and in connection with DWIN entering into the Purchase Agreement, DWIN and the investors party to the previously disclosed backstop subscription agreements have agreed, with approval from FOXO, to amend the Backstop Subscription Agreements, and, in connection therewith, it is no longer anticipated that the Backstop Investors will subscribe for DWIN shares concurrent with the consummation of the Business Combination. DWIN will hold a Special Meeting of Stockholders on September 14 to approve the Business Combination and the other proposals set forth.
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GOOG GOOGL | Hot Stocks05:36 EDT EU court upholds antitrust ruling against Google, reduces fine to EUR 4.125B - The European Union's General Court on Wednesday upheld an antitrust ruling against Google's parent company Alphabet but reduced its fine to EUR 4.125B from EUR 4.34B. The court said it "largely confirms the Commission's decision that Google imposed unlawful restrictions on manufacturers of Android mobile devices and mobile network operators in order to consolidate the dominant position of its search engine." It added that "In order better to reflect the gravity and duration of the infringement, the General Court considers it appropriate however to impose a fine of EUR 4.125B on Google, its reasoning differing in certain respects from that of the Commission." Reference Link
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AMCR | Hot Stocks05:22 EDT Amcor announces further $45M investment in ePac Flexible Packaging - Amcor announced a further strategic investment of up to $45M in ePac Flexible Packaging. The investment will increase Amcor's minority shareholding in ePac Holdings. Founded in 2016, ePac is focused on digital printing technologies to service the short run needs of small customers in the consumer goods industry. Annual revenue has grown more than 600% over the past three years to a run rate of over $200M. ePac operates 25 sites globally, all with an identical set-up, offering customers automated quoting, digital printing capabilities and exceptional service times across a number of product specifications.
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MLCO | Hot Stocks05:19 EDT Melco Resorts & Entertainment submits application for Macau gaming concession - Melco Resorts & Entertainment announced that Melco Resorts Macau, a subsidiary of the company, submitted its detailed proposal in relation to the public tender for new gaming concessions launched by the Macau Government in July this year.
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SLB | Hot Stocks05:18 EDT Schlumberger, Cognite announce integration partnership - Schlumberger and Cognite announced a strategic partnership to integrate Schlumberger's Enterprise Data Solution for subsurface with Cognite Data Fusion, Cognite's open industrial DataOps platform. Through this partnership, customers can integrate data from reservoirs, wells, and facilities in a single, open platform, and leverage embedded AI and advanced analytics tools to optimize production, reduce costs and decrease operational footprint.
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IBM | Hot Stocks05:17 EDT IBM, Bharti Airtel announce collaboration - IBM and Bharti Airtel announced their intent to work together to deploy Airtel's edge computing platform in India, which will include 120 network data centers across 20 cities. Once deployed, the platform is designed to enable large enterprises across multiple industries including manufacturing and automotive to accelerate innovative solutions that deliver new value to their clients and operations.
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IDEX | Hot Stocks05:12 EDT Ideanomics, ABC Companies enter reseller agreement - Ideanomics announced an agreement with ABC Companies, a provider of motorcoach, transit and specialty passenger transport equipment in the USA and Canada, allowing ABC Companies to become a certified reseller of Wave's wireless inductive charging technology in North America. The resale partnership expands Wave's distribution across North America and into private charter fleets.
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LVS SCHYY | Hot Stocks05:10 EDT Las Vegas Sands, Sands China submit application new Macao gaming concession - Las Vegas Sands (LVS) and Sands China (SCHYY) announced the submission of the Sands China group's application for a new 10-year gaming concession in Macao. The company also announced that Dave Sun MinQi, who has served as Sands China's chief financial officer since 2017 and has been with the company since 2007, has been proposed to also act as the future managing director of Venetian Macau. Additionally, Grant Chum Kwan Lock, who serves as chief operating officer and a member of the Sands China's board of directors, is also taking on the role of executive vice president of Asia operations for Las Vegas Sands.
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