Stockwinners Market Radar for December 03, 2021 - Earnings, Upgrades downgrades, option trades, Best Stock Advisory Service

MRK

Hot Stocks

18:17 EST FDA approves Merck's KEYTRUDA for adjuvant treatment of stage IIB, IIC melanoma - Merck announced that the U.S. Food and Drug Administration has approved KEYTRUDA, Merck's anti-PD-1 therapy, for the adjuvant treatment of adult and pediatric patients with stage IIB or IIC melanoma following complete resection. Additionally, the FDA expanded the indication for KEYTRUDA as adjuvant treatment for stage III melanoma following complete resection to include pediatric patients. The approval in stage IIB and IIC melanoma is based on data from the first interim analysis of the Phase 3 KEYNOTE-716 trial, in which KEYTRUDA showed a statistically significant improvement in recurrence-free survival (RFS), reducing the risk of disease recurrence or death by 35% compared to placebo. Median RFS was not reached for either group. After a median follow-up of 14.4 months, 11% of patients who received KEYTRUDA had recurrence or died compared to 17% of patients who received placebo. Efficacy in pediatric patients with stage IIB, IIC and III melanoma is supported by extrapolation of efficacy data from adults, given similar biology, pharmacology of drug effect, as well as similar exposure-response for efficacy and safety.
PSTG

Hot Stocks

18:12 EST Pure Storage director Tomb sells 29,311 class A shares - In a regulatory filing, Pure Storage director Gregory Tomb disclosed the sale of 29,311 class A common shares of the company on December 2 at a price of $31.4456 per share.
LGIH

Hot Stocks

17:56 EST LGI Homes reports 797 home closings in November - LGI Homes announced it closed 797 homes in November 2021. The company ended the first eleven months of 2021 with 9,438 home closings, a 22.4% increase over 7,709 home closings during the first eleven months of 2020. As of November 30, 2021, the company had 104 active selling communities.
BOKF

Hot Stocks

17:49 EST BOK Financial CFO Nell sells 8,000 common shares - In a regulatory filing, BOK Financial CFO Steven Nell disclosed the sale of 8,000 common shares of the company on December 2 at a price of $106.1252 per share.
SEDG

Hot Stocks

17:44 EST SolarEdge jumps 2.6% to $315.10 after being included in S&P500 effective 12/20
ASAN

Hot Stocks

17:43 EST Asana CEO buys $25M in common stock - In a regulatory filing, Asana disclosed that its CEO Dustin Moskovitz bought 250K shares of common stock on December 1st in a total transaction size of $25.0M, boosting his stake by about 3%.
SBNY...

Hot Stocks

17:40 EST Signature Bank, SolarEdge named to join the S&P 500 on December 20 - S&P Dow Jones Indices will make several index changes to the S&P 500, S&P MidCap 400, and S&P SmallCap 600 to ensure each index is more representative of its market capitalization range. The changes will be effective prior to the open of trading on Monday, December 20, 2021 to coincide with the quarterly rebalance: S&P MidCap 400 constituents Signature Bank (SBNY), SolarEdge Technologies Inc. (SEDG) and FactSet Research Systems Inc. (FDS) will move to the S&P 500, replacing S&P 500 constituents Leggett & Platt Inc. (LEG), Hanesbrands Inc. (HBI) and The Western Union Co. (WU), all of which will move to the S&P MidCap 400. S&P SmallCap 600 constituents Macy's Inc. (M), Vicor Corp. (VICR) and Power Integrations Inc. (POWI) will move to the S&P MidCap 400, replacing S&P MidCap 400 constituents Tootsie Roll Industries Inc. (TR), Telephone and Data Systems Inc. (TDS), and Nektar Therapeutics (NKTR), all of which will move to the S&P SmallCap 600.
POWI NKTR

Hot Stocks

17:37 EST Power Integrations to replace Nektar in S&P MidCap 400 on 12/20
NKTR POWI

Hot Stocks

17:34 EST Nektar Therapeutics to replace Power Integrations in S&P SmallCap 600 on 12/20
TDS VICR

Hot Stocks

17:34 EST Telephone & Data Systems to replace Vicor in S&P SmallCap 600 on 12/20
TR M

Hot Stocks

17:33 EST Tootsie Roll to replace Macy's in S&P SmallCap 600 on 12/20
VICR TDS

Hot Stocks

17:33 EST Vicor to replace Telephone and Data Systems on S&P400 on 12/20
VICR TDS

Hot Stocks

17:33 EST Vicor to replace Telephone and Dat Systems on S&P400 on 12/20
M TR

Hot Stocks

17:32 EST Macy's to replace Tootsie Roll Industries in S&P400 on 12/20
FDS WU

Hot Stocks

17:30 EST FactSet Research to replace Western Union in S&P500 on 12/20
SEDG HBI

Hot Stocks

17:29 EST SolarEdge to replace Hanesbrands in S&P500 on 12/20
SBNY LEG

Hot Stocks

17:28 EST Signature Bank to replace Leggett & Platt in S&P500 on 12/20
AES

Hot Stocks

17:03 EST AES Corp. increases quarterly dividend 5% to 15.8c per share - The board of directors of AES Corp. approved an increase of 5% in the company's quarterly common stock dividend, from 15.05c per share to 15.8c per share, beginning in Q1 of 2022.The company's first quarter common stock dividend of 15.8c per share is payable on February 15, 2022 to shareholders of record at the close of business on February 1, 2022.
RUN

Hot Stocks

16:47 EST Sunrun COO Christopher Dawson to step down effective December 31, 2021 - According to a regulatory filing, on December 2, 2021, Christopher Dawson notified Sunrun Inc. of his intention to step down from the role of Chief Operating Officer and separate from the company and its subsidiaries, effective December 31, 2021.
FCPT

Hot Stocks

16:42 EST Four Corners Property Trust acquires RadNet Imaging property for $2.2M - Four Corners Property Trust announced the acquisition of a RadNet Imaging property for $2.2M. The property is located in a strong retail corridor in Florida and is corporate-operated under a net lease with approximately six years of term remaining. The transaction was priced at a 7% going-in cash capitalization rate, exclusive of transaction costs.
PYCR

Hot Stocks

16:33 EST Paycor CEO Villar acquires 25,000 common shares - In a regulatory filing, Paycor HCM CEO Raul Villar disclosed the purchase of 25,000 common shares of the company on December 1 at a price of $29.35 per share.
SMTC

Hot Stocks

16:30 EST Semtech, Spark Connected announce settlement of litigation - Semtech Corporation and Spark Connected, LLC announced that they have resolved their dispute pending in the United States District Court for the Eastern District of Texas, Case No. 4:18-cv-00748. Semtech's Executive Vice President, Chief Legal Officer and Chief ESG Officer, Charles Ammann stated: "We are pleased with the outcome of this settlement. As it did in this lawsuit, Semtech is committed to taking steps to vigorously protect its intellectual property rights and confidential information and to enforce its confidentiality agreements and other contractual commitments."
ABBV

Hot Stocks

16:18 EST AbbVie provides update to Rinvoq medication guide - AbbVie announced an update to the U.S. Prescribing Information and Medication Guide for Rinvoq for the treatment of adults with moderate to severe rheumatoid arthritis, or RA. This update follows a Drug Safety Communication, or DSC, issued on September 1 by the FDA following its final review of the post-marketing study, ORAL Surveillance, evaluating Xeljanz in patients with RA. The results of this study showed a higher rate of major adverse cardiac events, or MACE, malignancy, mortality and thrombosis in Xeljanz versus TNF blockers.1 The DSC and this label update apply to the class of systemically administered FDA-approved JAKs indicated for the treatment of RA and other inflammatory diseases. Based on this class-wide update, the U.S. label for Rinvoq will now include additional information about the risks of malignancy and thrombosis, and the addition of mortality and MACE risks within the Boxed Warnings and Warnings and Precautions sections. The indication has also been updated to the following: Rinvoq is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to one or more TNF blockers.
GIG

Hot Stocks

16:16 EST GigCapital4, BigBear.ai announces shareholder approval of business combination - GigCapital4, a special purpose acquisition company, and BigBear.ai, a provider of artificial intelligence machine learning, cloud-based big data analytics, and cyber engineering solutions, announced that at the Special Meeting of GigCapital4's stockholders held today, GigCapital4's shareholders voted to approve the previously announced proposed business combination between GigCapital4 and BigBear.ai, as well as all other proposals related to the Business Combination. GigCapital4 plans to file the results of the Special Meeting, as tabulated by an independent inspector of elections, on Form 8-K with the Securities and Exchange Commission today.
PCH CTVA

Hot Stocks

16:12 EST PotlatchDeltic names Anne Alonzo to board of directors - PotlatchDeltic Corporation (PCH) announced the election of Anne L. Alonzo to PotlatchDeltic's Board of Directors, effective today. Alonzo most recently served as Senior Vice President, External Affairs and Chief Sustainability Officer for Corteva Agriscience (CTVA), a publicly traded global agricultural chemical and seed company.
PCH

Hot Stocks

16:11 EST PotlatchDeltic raises quarterly distribution 7.3% to 44c per share - The board of directors of PotlatchDeltic Corporation declared a Special Dividend on the company's common stock. The distribution of $4.00 per share is payable December 31, 2021 to stockholders of record on December 22, 2021. The board of directors of PotlatchDeltic Corporation also declared a quarterly distribution on the company's common stock. The distribution of 44c per share is payable December 31, 2021 to stockholders of record on December 15, 2021. This is a 7.3% increase compared to the prior quarterly dividend of 41c per share.
LLY ABCL

Hot Stocks

16:06 EST AbCellera says FDA expands EUA for bamlanivimab-etesevimab combo - AbCellera (ABCL) announced the U.S. Food and Drug Administration has expanded the Emergency Use Authorization for bamlanivimab and etesevimab administered together to include pediatric patients under the age of 12, including neonates. The EUA allows for bamlanivimab and etesevimab administered together in the treatment of mild to moderate COVID-19 as well as post-exposure prophylaxis in certain patients. The expanded EUA is based on data from the BLAZE-1 Phase 2/3 clinical trial studying bamlanivimab and etesevimab administered together for the treatment of pediatric and infant patients with mild to moderate COVID-19 and who are at high risk for severe disease progression. The median time to complete symptom resolution as recorded in a trial specific daily symptom diary was 7 days for subjects treated with bamlanivimab 700 mg and etesevimab 1,400 mg and 5 days for subjects treated with weight-based dosing of bamlanivimab and etesevimab. No subject died or required hospitalization due to COVID-19. Pseudovirus and authentic virus studies conducted by AbCellera's partner, Eli Lilly and Company (LLY), demonstrate that bamlanivimab and etesevimab together retain neutralization activity against the Delta variant, which is currently the predominant variant of concern within the U.S.
MORN

Hot Stocks

16:04 EST Morningstar raises quarterly dividend 14.3% to 36c per share - The board of directors of Morningstar declared a quarterly dividend of 36c per share. The dividend is payable Jan. 31, 2022 to shareholders of record as of Jan. 7, 2022. The 14.3% increase from the prior quarterly rate of 31.5c per share results in an annualized dividend of $1.44 per share compared with the prior annualized rate of $1.26 per share.
AMGN

Hot Stocks

16:00 EST Amgen raises quarterly dividend 10% to $1.94 per share - Amgen announced that its Board of Directors declared a $1.94 per share dividend for the first quarter of 2022. The dividend will be paid on March 8, 2022, to all stockholders of record as of the close of business on February 15, 2022. This represents a 10% increase from that paid in each of the previous four quarters.
HHS HRTH

Hot Stocks

14:57 EST Harte Hanks to uplist to Nasdaq Global Market - Harte Hanks announced that the company has met the financial, liquidity and corporate governance listing requirements of the Nasdaq Global Market and the company has been approved for listing on the Nasdaq. Trading on Nasdaq is expected to commence at the market open on December 1, and the shares will trade under the ticker symbol "HHS". The company's shares will continue to trade on the OTCQX under the symbol "HRTH" until trading on the Nasdaq commences. Shareholders are not required to take any action as a result of the uplisting and symbol change, the company stated. "Uplisting to the Nasdaq marks another major milestone for Harte Hanks. With the expanded audience of investors, increased access to liquidity, and the significant improvement in our financial performance, we are well positioned for future profitable growth. Harte Hanks traded under the ticker 'HHS' for nearly 50 years, from its IPO in 1972 through 2020, and returning to a national exchange and this longstanding ticker symbol is an important indication of the progress we have made," said Harte Hanks' Chairman of the Board of Directors Jack Griffin.
LLY

Hot Stocks

14:54 EST Eli Lilly confirms FDA expanded EUA for bamlanivimab and etesevimab combo - The U.S. Food and Drug Administration has expanded the Emergency Use Authorization, or EUA, for bamlanivimab and etesevimab administered together to include certain high-risk pediatric patients from birth to less than 12 years old, Eli Lilly and Company announced. This expansion allows for bamlanivimab and etesevimab to be administered together in high-risk pediatric patients for the treatment of mild to moderate COVID-19 as well as post-exposure prophylaxis, the company noted. "Our mission since the start of the pandemic has been to offer crucial support by developing therapeutic options that could prevent hospitalization and death for as many people as possible. With the FDA's decision to allow use of bamlanivimab with etesevimab in children and infants, Lilly can now offer treatment and prevention options to high-risk individuals of any age," said Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific and medical officer, and president of Lilly Research Laboratories.
CDZI

Hot Stocks

14:48 EST Cadiz says 'immediate opportunity is manifest by the Cadiz Northern Pipeline' - Cadiz CEO Scott Slater released a statement in response to the California Department of Water Resources' announcement that it will allocate zero water to its 29 contract water districts next year, stating in part: ""The State water outlook turned gloomier this week; if that's possible. Following the already significant curtailments of 2021, the California Department of Water Resources confirmed Wednesday that the State will not be honoring contracts for the delivery of water to 25 million people and 750,000 acres of California farmland and is forecasting a zero allocation of water for the first time in history. Instead of meeting contractual allocations, DWR will apportion water among contract holders based upon its assessment of essential needs and will place DWR in the unenviable position of picking winners and losers. This historic drought in California and throughout the Southwest continues to take a devastating toll on the State's existing system, and on the tens of millions of families who continue to see mandatory cutbacks with no indication that conditions will improve. Conservation efforts are critical to addressing this crisis, but more action is needed. As the State of California continues to address supply inequalities and infrastructure challenges that most significantly impact its disadvantaged communities, Cadiz is deeply committed to enhancing California's water transportation network to improve water access for all. An immediate opportunity is manifest by the Cadiz Northern Pipeline, which spans 220 miles and crosses important state infrastructure... The company also continues to offer potential beneficial water supply for 200,000 people through conservation of groundwater lost to salinity and evaporation, which is CEQA approved, regulated by local authorities, and continues to wind its way through the regulatory process. Our message is simple: Californians need water access. Cadiz can help. Let's work together to get water to the millions of people who desperately need it."
TWTR

Hot Stocks

14:34 EST Twitter CEO restructuring leadership team, Engineering Lead stepping down - In a regulatory filing, Twitter disclosed that Chief Executive Officer Parag Agrawal is restructuring the leadership team "to drive increased accountability, speed, and operational efficiency," shifting to a General Manager model for Consumer, Revenue, and Core Tech, which will be led by Kayvon Beykpour, Bruce Falck, and Nick Caldwell, respectively. "These GMs will lead all core teams across engineering, product management, design, and research. Lindsey Iannucci also joined the leadership team as Chief of Staff and Vice President of Operations to support Mr. Agrawal in strengthening operations across the leadership team, and the company," the filing stated. Twitter announced that as part of the organizational changes referenced, Michael Montano, Engineering Lead, will be stepping down from his position at the company effective December 31, 2021. Montano will remain an advisor of the company through the end of the first quarter of 2022 to ensure an orderly transition. Also as part of these changes, Dantley Davis, Design and Research Lead, will be stepping down from his position at the company effective December 31, 2021, and will remain an advisor through the end of the first quarter of 2022 to ensure an orderly transition.
LLY

Hot Stocks

14:30 EST FDA expands authorization of Eli Lilly COVID-19 antibodies to younger patients - The U.S. Food and Drug Administration revised the emergency use authorization of bamlanivimab and etesevimab, previously authorized for pediatric patients 12 years of age and older weighing at least 40 kilograms, or about 88 pounds, to additionally authorize bamlanivimab and etesivimab administered together for the treatment of mild to moderate COVID-19 in all younger pediatric patients, including newborns, who have a positive COVID-19 test and are at high risk for progression to severe COVID-19, including hospitalization or death. This revision also authorizes bamlanivimab and etesevimab, to be administered together, for post-exposure prophylaxis for prevention of COVID-19 in all pediatric patients, including newborns, at high risk of progression to severe COVID-19, including hospitalization or death. The EUA was issued to Eli Lilly and Co. Reference Link
MRK

Hot Stocks

14:09 EST Merck enters supply agreement with Canada for up to 1M courses of molnupiravir - Merck announced that it has entered into a Supply Agreement with the Government of Canada for up to 1 million patient courses of molnupiravir, its investigational oral antiviral medicine for the treatment of COVID-19. This investigational medicine is being developed by Merck in collaboration with Ridgeback Biotherapeutics. Through this agreement, the Government of Canada has secured access in 2022 to 500,000 patient courses, with options for up to 500,000 more, pending Health Canada approval. This new agreement is part of Merck's commitment to make this investigational medicine widely available globally, if approved for use by regulatory agencies. In November, Merck Canada filed the final wave of the molnupiravir rolling submission to Health Canada, which will decide on the therapy's approval only when all necessary evidence has been reviewed.
CHGG

Hot Stocks

13:54 EST Chegg director Schlein acquires 35,470 common shares - In a regulatory filing, Chegg director Ted Schlein disclosed the purchase of 35,470 common shares of the company on December 2 at a price of $28.54 per share.
WBA

Hot Stocks

13:26 EST Walgreens Boots Alliance up 4% to $46.29 after Sky says exploring Boots sale
QTNT

Hot Stocks

13:21 EST Quotient up 8% after Defense Logistics Agency award posting - Shares of Quotient Limited are up 18c, or 8%, to $2.54 as traders circulate a SAM.gov posting that shows Quotient Biodiagnostics was awarded a contract from the Defense Logistics Agency on Nov 22. The total contract value for the base and all options is $77,326,120, according to the posting to the government site. Reference Link
BKR

Hot Stocks

13:05 EST Baker Hughes reports U.S. rig count unchanged from last week at 569 - Baker Hughes reports the U.S. rig count is unchanged from last week at 569 with oil rigs unchanged at 467, gas rigs unchanged at 102, and miscellaneous rigs unchanged at zero. The U.S. rig count is up 246 rigs from last year's count of 323, with oil rigs up 221 gas rigs up 27 and miscellaneous rigs down two. The U.S. offshore rig count is down two to 13, unchanged year-over-year. Baker Hughes said the Canada rig count is up nine from last week to 180, with oil rigs up seven to 113 and gas rigs up two to 67. The Canada rig count is up 78 rigs from last year's count of 102, with oil rigs up 73 and gas rigs up five.
AGR PNM

Hot Stocks

12:44 EST 15 organization officials voice support for PNM-Avangrid deal - PNM Resources (PNM) and AVANGRID, Inc. (AGR) answered open questions at a news conference about their proposed merger and addressed some concerns heard at the New Mexico Public Regulation Commission open meeting on Wednesday, December 1, 2021. Joining PNM Resources and AVANGRID were elected officials and organizations representing customers and business representing tens of thousands of New Mexicans. Organizations that spoke in favor of the merger included the New Mexico Office of the Attorney General, the All-Pueblo Council of Governors, the New Mexico Chamber of Commerce, the Greater Albuquerque Chamber of Commerce, the Albuquerque Hispano Chamber of Commerce, and Western Resource Advocates. Other supporting organizations represented were Ralph Arellanes with the Hispano Roundtable, Joseph Hernandez with the Native American Voters Alliance, Noah Long with the Natural Resources Defense Council, Cara Lynch with the Coalition for Clean and Affordable Energy, Kyle Tisdale with the Western Environmental Law Center, The Office of Representative Javier Martinez, Lawrence Rael with the City of Albuquerque, Keith Kirk with the Santa Fe Lodgers Association, and Shannon Fitzgerald with International Brotherhood of Electrical Workers. Not only are existing supporters holding steadfast, the merger continues to gather support. Chairman Wilfred Herrera on the All-Pueblo Council of Governors representing 20 Pueblo Governors of New Mexico announced that the APCG has formally endorsed the merger. This coming week additional supporters are expected to be announced.
FTV

Hot Stocks

12:28 EST Fortive to acquire Provation for $1.425B - Fortive Corporation announced that it has entered into a definitive agreement with Clearlake Capital Group to acquire Provation Software, a provider of clinical workflow software solutions used in hospitals and ASCs, for $1.425B. The acquisition is subject to customary closing conditions and regulatory approvals and is expected to close by the end of the year. Fortive expects to finance the acquisition with short-term debt and available cash, and estimates the acquisition will be accretive to adjusted diluted net earnings per share by greater than 8c in fiscal 2022. James Lico, President and CEO of Fortive, stated: "We are extremely excited to announce the pending addition of Provation to the Fortive team. Provation is a best-in-class healthcare software provider, delivering safe, efficient and scalable procedure documentation and clinical decision support solutions to thousands of health systems, hospitals and ASCs. This acquisition will bring extensive software development expertise and innovation capabilities to the AHS segment, significantly accelerating our segment strategy to provide critical workflow solutions for hospitals and ASCs. Adding Provation's software offering and broad customer coverage to existing positions at ASP and Censis will broaden our growth opportunities across the segment."
FTV

Hot Stocks

12:27 EST Fortive to acquire Provation for $1.425B
TWTR

Hot Stocks

12:24 EST Twitter removes 3,465 state-linked information accounts in six countries - Yesterday, Twitter disclosed an additional 3,465 accounts to its archive of state-linked information operations. The account sets include eight distinct operations the company has attributed to six countries - Mexico, the People's Republic of China, Russia, Tanzania, Uganda, and Venezuela, respectively. Every account and piece of content associated with these operations has been permanently removed from the service. "In addition, we have shared relevant data from this disclosure with three leading research partners: the Australian Strategic Policy Institute (ASPI), Cazadores de Fake News, and the Stanford Internet Observatory (SIO)," Twitter said. "In most instances, accounts were suspended for various violations of our platform manipulation and spam policies. See more via our Transparency Center." Reference Link
DIDI

Hot Stocks

12:00 EST Didi falls -17.3% - Didi is down -17.3%, or -$1.35 to $6.45.
SG

Hot Stocks

12:00 EST Sweetgreen falls -17.6% - Sweetgreen is down -17.6%, or -$5.39 to $25.28.
ASAN

Hot Stocks

12:00 EST Asana falls -25.1% - Asana is down -25.1%, or -$22.86 to $68.14.
BIG

Hot Stocks

12:00 EST Big Lots rises 7.3% - Big Lots is up 7.3%, or $3.20 to $46.82.
TLYS

Hot Stocks

12:00 EST Tilly's rises 12.1% - Tilly's is up 12.1%, or $1.74 to $16.17.
HGTY

Hot Stocks

12:00 EST Hagerty rises 21.0% - Hagerty is up 21.0%, or $2.23 to $12.89.
VALN...

Hot Stocks

11:52 EST Valneva thinks time between second shot, booster may hurt VLA2001 trial results - Valneva SE (VALN) responded to data published from the COV-Boost COVID-19 vaccine trial, which investigated the reactogenicity and immunogenicity of seven different COVID-19 vaccines at different dose levels when administered as a third dose, or booster, to people primed with either Pfizer's (PFE) Comirnaty or AstraZeneca's (AZN) Vaxzevria. "The COV-Boost trial, which launched in May 2021 and was led by University Hospital Southampton NHS Foundation Trust, included Valneva's inactivated, adjuvanted, whole virus COVID-19 vaccine candidate VLA2001. The aim of the COV-Boost trial was to quickly generate data to inform advice from the UK's Joint Committee on Vaccination and Immunization on the autumn booster campaign. Participants were given a booster dose relatively early, only two to three months after completion of the second dose of the primary vaccination series, when they did not need a booster from either an immunological standpoint or under the currently recommended interval for licensed COVID-19 vaccines. Valneva believes it is likely that the short interval between the second shot and booster shot could have adversely impacted the results for VLA2001, given that a longer interval is generally required for inactivated vaccines," the company said. Juan Carlos Jaramillo, MD, Chief Medical Officer of Valneva, added, "The setting in the study leads us to believe that COV-Boost does not allow any conclusions to be reached regarding the use of VLA2001 as a booster in a real-life setting. The protective antibody threshold has not yet been established therefore relative increases in antibody levels should not be seen as indicative of efficacy. I concur with Professor Faust's statements that the data describe the immune response at 28 days, not vaccine effectiveness, and that the relationship between that response and long-term protection is still poorly understood, especially since several studies have shown that longer periods between doses improve immune response. Our submissions for authorization of VLA2001 in a primary vaccination context remain on track, with the EMA announcing yesterday that it has started its rolling review of VLA2001, and our teams are working diligently so that we can quickly deploy our vaccine and ensure it reaches the people who need it."
VUZI

Hot Stocks

11:47 EST Vuzix signs distribution agreement with Barcotec - Vuzix Corporation announced that it has signed a distribution agreement with Barcotec, a European supplier of hardware, and has received and shipped against an initial order from them for Vuzix Smart Glasses.
GGG

Hot Stocks

11:44 EST Graco raises quarterly dividend 12% to 21c per share - The Board of Directors of Graco has declared a regular quarterly dividend of 21c per common share, an increase of 12%, payable on Feb. 2, 2022, to shareholders of record at the close of business on Jan. 18, 2022. The Company has approximately 170.2M shares outstanding.
SVA

Hot Stocks

11:26 EST Sinovac Biotech says subsidiary settled litigation with Aihua Pan - Sinovac Biotech announced the company's subsidiary Sinovac Beijing settled litigation with Mr. Aihua Pan concerning its business license and seals. "As disclosed previously, Mr. Aihua Pan made the false claim to certain government agencies that Sinovac Beijing's business license, official corporate seal, financial seal, contract seal and invoice seal had been lost. Mr. Pan subsequently obtained a re-issued business license of Sinovac Beijing based on the false claim. Mr. Pan further obtained Sinovac Beijing's corporate seal (No.: 1101081347485), contract seal and invoice seal by using the re-issued business license. In December 2018, the People's Court in Haidian District, Beijing issued an interim injunction order restraining Mr. Aihua Pan from using or authorizing others to use the re-issued business license and the Seals of Sinovac Biotech that were improperly obtained by him. On November 30, 2021, SINOVAC settled the litigation with Mr. Aihua Pan in the Court. With the settlement, Mr. Pan has returned the business license and the Seals to Sinovac Beijing, and Sinovac Beijing has withdrawn its claims with the Court," the company stated.
RHHBY

Hot Stocks

10:16 EST FDA approves Roche's Rituxan with chemo for child cancers - The Food and Drug Administration announced the approval of Rituxan in combination with chemotherapy for pediatric patients with previously untreated, advanced stage, CD20-positive diffuse large B-cell lymphoma, Burkitt lymphoma, Burkitt-like lymphoma or mature B-cell acute leukemia. Reference Link
APSG...

Hot Stocks

10:11 EST Apollo Strategic to take AmEx Global Business Travel public in $5.3B deal - American Express Global Business Travel announced its entry into a definitive business combination agreement with special purpose acquisition company Apollo Strategic Growth Capital (APSG). The combined company plans to list on the New York Stock Exchange under the new ticker symbol "GBTG". Zoom Video (ZM), Sabre (SABR) and HG Vora are among a new group of investors committed to joining lobal Business Travel's private investment in public equity, or PIPE. Upon the closing of the transaction, these companies will join American Express (AXP) and Certares as shareholders. Under an 11-year agreement to take effect upon closure of the transaction, Global Business Travel will continue to have the right to use the American Express trademark in connection with the American Express Global Business Travel and American Express GBT Meetings & Events brands. The transaction implies a pro forma market capitalization of approximately $5.3B and a pro forma enterprise valuation of approximately $5B for GBT, assuming no redemptions by Apollo Strategic Growth's shareholders. Current GBT common equity holders are expected to roll their existing equity holdings into the combined company. The transaction is expected to provide up to approximately $1.2B in gross proceeds. Upon the closing of the transaction, the combined company will be renamed Global Business Travel Group, and will continue to conduct its day-to-day business under its existing name and brand American Express Global Business Travel.
CD

Hot Stocks

10:06 EST Chindata CEO Jing Ju to step down, Fei Xu to serve as interim CEO - Chindata Group Holdings announced its CEO Jing Ju, effective immediately, would no longer serve in the CEO position, or member of the Company's Compensation Committee and the Corporate Governance and Nominating Committee. After this change, each of the Compensation Committee and the Nominating and Corporate Governance Committee will now have two members. Fei Xu will serve as the interim CEO, while the search for a permanent CEO will commence immediately. Xu is currently an Executive Vice President and a member of the Portfolio Group for Bain Capital Private Equity.
FRHC

Hot Stocks

10:05 EST Freedom Holding agrees to acquire MKM Partners - Freedom Holding announced it has entered an agreement to acquire MKM Partners, a Stamford-based firm focused on Trading, Research, Sales, Derivatives, Event Driven/Risk Arbitrage, Proprietary Studies, Capital Markets, Corporate Access, High Yield/Credit, and CSA.. Under the terms of the agreement, Freedom will acquire all the member interest of MKM Partners for cash and Freedom common stock. Completion of the transaction is subject to certain conditions, including approval of FINRA. "MKM Partners is a well-respected institutional equity trading, sales, and research firm," said Timur Turlov, Freedom CEO. "With one of the largest distribution forces in the U.S. and a team of distinguished strategists and research analysts, MKM will further enhance Freedom's international team and extend our activities focused on U.S. growth." Upon closing, MKM will be led by Robert Wotczak, as CEO, and Sagar Sheth, current president of MKM Partners.
STOK

Hot Stocks

10:05 EST Stoke Therapeutics presents data from Phase 1/2a MONARCH study of STK-001 - Stoke Therapeutics announced highlights from five presentations related to the ongoing clinical development of STK-001 being made at the American Epilepsy Society 2021 Annual Meeting, December 3 - 7. STK-001 has the potential to be the first disease-modifying therapy to target the underlying cause of Dravet syndrome, which is a severe and progressive genetic epilepsy characterized by frequent, prolonged and refractory seizures beginning within the first year of life. The disease is classified as a developmental and epileptic encephalopathy due to the developmental delays and cognitive impairment associated with the disease. Interim Safety, PK, and CSF Exposure Data from the Phase 1/2a MONARCH Study of STK-001, an Antisense Oligonucleotide, in Children and Adolescents with Dravet Syndrome: Highlights include: Single doses of STK-001 up to 30mg, and three 20mg doses of STK-001 given every four weeks, were found to be well tolerated with no safety concerns related to the study drug. The most common treatment-emergent adverse events were headache, vomiting, seizure, irritability, and back pain. 18.2% of patients experienced a TEAE that was related to study drug, none of which were severe. 22.7% of patients had a serious treatment-emergent adverse event, none of which were related to study drug. 70.6% of patients treated with single doses or multiple doses of STK-001 experienced a reduction from baseline in convulsive seizure frequency measured from Day 29 to Day 84 after receiving their first dose of STK-001. All patients ages 2-12 experienced a reduction from baseline in convulsive seizure frequency measured from Day 29 to Day 84. Reductions in seizure frequency were also observed among patients ages 13-18. Across all cohorts median reductions of 17% to 37% from baseline in convulsive seizure frequency from Day 29 to Day 84 were observed. Additional posters include: SWALLOWTAIL: An Open-Label Extension Study for Patients with Dravet Syndrome who Previously Participated in Studies of STK-001: Clinical data from the continued administration of STK-001 to patients previously treated in the Phase 1/2a MONARCH study demonstrated that multiple doses up to 30mg of STK-001 were well tolerated with no safety concerns related to the study drug. Additionally, dosing of STK-001 intrathecally every four months appears to be well tolerated. No patients have discontinued treatment in SWALLOWTAIL. A Pharmacokinetic Model for STK-001, an Antisense Oligonucleotide, Based on Data from Non-human Primates Enables Dose Selection in Patients with Dravet Syndrome: A population pharmacokinetic model for intrathecal STK-001 was developed using non-human primate data and was scaled and adjusted using clinical data to predict STK-001 concentrations in plasma, CSF and brain in pediatric patients with Dravet syndrome. STK-001 levels in plasma and CSF in patients treated with STK-001 correlated very well with model predictions, indicating that plasma and CSF levels observed in patients are good predictors of STK-001 brain levels in patients. Modeling of clinical data also suggest that more than 95% of patients are predicted to have pharmacologically active STK-001 brain levels following three doses of 30mg administered one month apart and half of all patients are anticipated to maintain greater than minimum pharmacologically active levels of STK-001 for approximately three months after their last dose. ADMIRAL: A UK Open-Label Study to Investigate the Safety and Pharmacokinetics of Multiple Ascending Doses of Antisense Oligonucleotide STK-001 in Children and Adolescents with Dravet Syndrome: Provides the trial design of the Company's ongoing Phase 1/2a study in the United Kingdom. This study is evaluating multiple doses of up to 70mg of STK-001. The primary endpoints are safety and tolerability of STK-001 as well as to determine the PK in plasma and exposure in CSF. The impact of STK-001 on frequency of convulsive seizures and quality of life are secondary endpoints of this study. Enrollment and dosing in ADMIRAL is ongoing. BUTTERFLY, An Observational Study to Investigate Cognition and Other Non-seizure Comorbidities in Children and Adolescents with Dravet Syndrome: Three-month data suggest that commonly used cognition assessments including the VABS-III, BSID-III, and WPPSI-IV may be useful for clinical studies assessing neurodevelopment and adaptive behavior in patients with Dravet syndrome. All three assessments showed relatively low intra-patient variability and no significant change from baseline three months after baseline assessments for all 36 patients enrolled.
MRNS

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10:02 EST Marinus announces new clinical and research data to be presented at AES - Marinus Pharmaceuticals announced new clinical trial and research data being presented at the American Epilepsy Society, or AES, Annual Meeting in Chicago, Illinois, including new quality of life and extended safety and efficacy data of ganaxolone in CDKL5 deficiency disorder, or CDD, and a quantitative EEG analysis and case reports of patients in super-refractory status epilepticus. "We are honored to be at the AES Meeting this year after almost a year of planning from our medical and scientific affairs, clinical, and advocacy teams, with nine presentations spanning our IV and oral portfolio-Marinus' largest data showing to date. We look forward to sharing clinical trial data supporting the potential of ganaxolone to treat a range of seizure disorders as well as research data highlighting the impact that seizures can have on developmental progressions and quality of life in children with CDD," said Scott Braunstein, M.D., CEO of Marinus Pharmaceuticals.
LU

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10:00 EST Lufax falls -10.5% - Lufax is down -10.5%, or -66c to $5.63.
DAO

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10:00 EST Youdao falls -11.4% - Youdao is down -11.4%, or -$1.53 to $11.87.
ASAN

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10:00 EST Asana falls -25.4% - Asana is down -25.4%, or -$23.14 to $67.86.
TLYS

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10:00 EST Tilly's rises 10.3% - Tilly's is up 10.3%, or $1.48 to $15.91.
SMAR

Hot Stocks

10:00 EST Smartsheet rises 11.3% - Smartsheet is up 11.3%, or $6.89 to $68.05.
HGTY

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10:00 EST Hagerty rises 17.3% - Hagerty is up 17.3%, or $1.84 to $12.50.
ENFA BZFD

Hot Stocks

09:50 EST 890 5th Avenue stockholders approve business combination with Buzzfeed - 890 5th Avenue Partners (ENFA) announced last night that its stockholders approved the proposals that were conditions to the closing of the previously announced business combination with BuzzFeed (BZFD) at a special meeting of stockholders held yesterday. The closing of the Business Combination is expected to occur on or about December 3, 2021, subject to the satisfaction or waiver of all closing conditions. Following the closing of the Business Combination, the combined company will be known as BuzzFeed and its shares of Class A common stock are expected to commence trading on The Nasdaq Stock Market LLC under the symbol "BZFD" on Monday, December 6, 2021. The closing of BuzzFeed's previously announced acquisition of Complex Networks is expected to occur on the same day as the closing of the Business Combination. The transaction is expected to raise at least $166.2M from a combination of 890 trust proceeds and fully committed convertible notes. 890 shares closed at $9.91 per share on December 2, 2021, and stockholders who elected to redeem will receive approximately $10.00 per share.
LU

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09:47 EST Lufax falls -7.2% - Lufax is down -7.2%, or -45c to $5.84.
RLX

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09:47 EST RLX Technology falls -7.9% - RLX Technology is down -7.9%, or -35c to $4.08.
ASAN

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09:47 EST Asana falls -23.8% - Asana is down -23.8%, or -$21.68 to $69.32.
YEXT

Hot Stocks

09:47 EST Yext rises 10.8% - Yext is up 10.8%, or $1.02 to $10.45.
HGTY

Hot Stocks

09:47 EST Hagerty rises 11.8% - Hagerty is up 11.8%, or $1.26 to $11.92.
SMAR

Hot Stocks

09:47 EST Smartsheet rises 13.3% - Smartsheet is up 13.3%, or $8.11 to $69.27.
IOBT

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09:42 EST IOBT Stock trading resumes
F

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09:38 EST Ford reports nearly 200K reservations for F-150 Lightning - In presentation slides for Ford COO of North America Lisa Drake's presentation at Goldman Sachs' Global Auto Conference, the automaker reports that it has nearly 200,000 reservations for the F-150 Lightning, which will be available in Spring 2022, and 22,000 units sales year to date in the U.S. for the Mustang Mach E, which launched in December 2020. The company is also seeing "high demand" for the E-Transit, with pilots underway with Penske and National Grid. Ford sees having 240 GWh of battery cell capacity globally by the end of the decade, with 140 GWh in North America and the remaining GWh split between Europe and China, the slides added. Reference Link
ICL

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09:36 EST ICL receives approval for ICL Boulby Mine's application - ICL announced the North York Moors Park Authority Planning Committee approved the ICL Boulby Mine's application for the continuation of polyhalite and salt production for an additional 25 years, which will begin in 2023 when the current planning permission expires.
CIDM

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09:33 EST Cinedigm, LiveLike partner for community, gamification elements - Cinedigm and LiveLike are partnering to deliver new community and gamification elements to Cinedigm's portfolio of premium streaming direct-to-consumer subscription services. LiveLike is an audience engagement platform that empowers its partners to make their content more interactive and social through a suite of tools that enhance the fan experience. Working with a wide range of clients from ecommerce, education, and news to live sports, music, and movie premieres, LiveLike integrates features such as influencer-driven chats, watch parties, loyalty rewards, user rankings, and more-any of which can be integrated with sponsors. Planned features to be directly integrated into the underlying Matchpoint Blueprint platform utilizing the LiveLike SDK will include chat, profiles, rewards, leaderboards, and badges.
IOBT

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09:32 EST IOBT Stock trading halted, volatility trading pause
YCBD

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09:31 EST cbdMD announces human clinical study with University of South Carolina - cbdMD announced that it has commenced a preclinical human study with researchers at the University of South Carolina. The study will explore the effects of cbdMD's proprietary broad spectrum cannabinoid blend on sleep, mood, and pain in healthy subjects to further support the efficacy of the Company's products. The studies will also be measuring key safety markers in healthy humans to augment the Company's safety dossiers for regulatory submissions. The Company anticipates that these favorable outcomes will be the basis for future drug research and applications by its therapeutics division.
EZGO

Hot Stocks

09:31 EST EZGO Technologies affiliate obtains right to operate e-bicycle sharing services - EZGO Technologies announced that an affiliate company of the xompany's PRC subsidiary has entered into an operation agreement with the Tancheng local administration in Linyi City, Shandong Province, whereby EZGO has exclusive rights to operate e-bicycle sharing services, providing up to 3,000 e-bicycles for bike-sharing purposes in the Tancheng local area. The term of this agreement is three years commencing from November 9, 2021 to November 8, 2024. Following the launch of its e-bicycle sharing services in Tancheng, EZGO anticipates expanding its bike-sharing business into cities in southern Shandong, planning to serve a population of more than 800 thousand. EZGO's integrated management platform of "bicycles + batteries + Internet" supports real-time control functions of electric bicycles, lithium batteries, on-board instruments and central controllers, improving the overall user experience and safety of e-bicycle sharing customers.
DSX

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09:28 EST Diana Shipping announces acquisition of new-building Capesize dry bulk vessel - Diana Shipping announced that on December 3, 2021, it signed through a separate wholly-owned subsidiary, a Memorandum of Agreement to acquire from an unaffiliated third party, a Japanese new-building Capesize dry bulk vessel of approximately 181,500 dwt, for a purchase gross price of $60,164,000. The vessel is expected to be delivered to the buyer by the end of the first quarter of 2022.
OMQS

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09:27 EST Omniq receives approximately $1M order for smart kiosks - OMNIQ announced that it received a purchase order for the advanced Kiosks developed by its Israeli subsidiary Dangot Computers Ltd. The project was ordered by a leading US automated solutions provider. OMNIQ will supply 500 Dangot smart kiosks integrated with AI-based machine vision technology and other advanced equipment. OMNIQ's customer operates across over 250 cities and thousands of locations in the US, generating more than $1B in revenue. The new project will roll out across locations in the US, with the first 100 kiosks shipped by the end of December and the additional units distributed over the next 18 months.
APPN

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09:20 EST Appian CFO Mark Lynch to retire - Appian announced that Mark Lynch intends to retire from his role as Chief Financial Officer effective March 31, 2022. Mr. Lynch will remain in his current position through March 31, 2022, to assist with the filing and certification of the Company's annual report on Form 10-K, and to support with the transition of his responsibilities to his successor, once named. The Company has initiated an executive search to fill the Chief Financial Officer position. In addition, Appian announced that it has promoted and designated Mark Matheos, Senior Vice President, Global Controller to Chief Accounting Officer effective December 31, 2021.
WETF

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09:19 EST WisdomTree launches diversified crypto exposures in the U.S., Europe - WisdomTree Investments announced an extension of its digital asset thought leadership through the creation of four new crypto indices that will underpin offerings for diversified crypto exposures for investors in both the U.S. and European markets. U.S. - WisdomTree Crypto Index: RWM WisdomTree Crypto Index. Europe - WisdomTree ETPs Tracking a WisdomTree Crypto Index: WisdomTree Crypto Mega Cap Equal Weight; WisdomTree Crypto Market; WisdomTree Crypto Altcoins. The RWM WisdomTree Crypto Index seeks to provide exposure to crypto assets from a thematic point of view with broad and diversified exposure to different crypto assets. Each crypto asset either plays, or has the potential to play, an important role within the crypto ecosystem and/or provides necessary services for the crypto ecosystem to flourish. In collaboration with Ritholtz Wealth Management, OnRamp and Gemini, WisdomTree is allowing financial advisors to execute this strategy through a packaged direct indexing solution. In Europe, WisdomTree enhanced its crypto ETP lineup with the launch of a trio of crypto asset baskets, in addition to our existing bitcoin and ether ETPs. These include: The WisdomTree Crypto Mega Cap Equal Weight, WisdomTree WT Crypto Market and WisdomTree Crypto Altcoins ETPs, each seeking to track the respective WisdomTree Crypto Index.
OP

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09:10 EST OceanPal announces short term contract for m/v Calipso - OceanPal announced that, it has entered into a time charter trip contract for its Panamax dry bulk vessel, the m/v Calipso, at a gross charter rate of $18,750 per day, for about fifteen to twenty days. The m/v Calipso is currently chartered at a gross charter rate of $10,400 per day. The "Calipso" is a 73,691 dwt Panamax dry bulk vessel built in 2005.
IAIC

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09:07 EST Information Analysis announces reorganization of government services business - Information Analysis Incorporated announced that it is restructuring and reorganizing its legacy services business and new Board appointments. Under the reorganization, IAI's existing professional services business will be combined with its Tellenger subsidiary. Tellenger will have a separate advisory board, led by Stan Reese and Charles May. Reese has more than 25 years of senior management experience and previously served briefly as IAI's CEO and was Chief Operating Officer for 20 years. Lieutenant General Charles May USAF is a consultant focusing on national security and defense conversion issues. This reorganization creates two open spots on the IAI Board of Directors, which will be filled by James "Chip" DiPaula and Rear Admiral Paul Becker. Rear Admiral Paul Becker served with distinction in the United States Navy in a career that spanned over 30 years as a Naval Intelligence Officer. Chip DiPaula is a Chip is the Co-Founder of Flywheel Digital, a pioneering digital advertising firm that optimizes ecommerce sales for the world's largest brands. DiPaula also serves as the Chairman of the University System of Maryland Medical System.
RNVA

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09:06 EST Rennova Health-owned hospital receives critical access hospital certification - Rennova Health announced that the application by its hospital, Scott County Community Hospital in Oneida, TN, for designation as a Critical Access Hospital has been approved by Centers for Medicare and Medicaid Services. The effective date of approval is retrospective to June 30, 2021.
CRXT

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09:05 EST Clarus Therapeutics announces $15M private placement - Clarus Therapeutics announced that it has entered into a definitive agreement to sell securities in a private placement with a leading healthcare investor. The gross proceeds to Clarus from the private placement, before deducting the placement agents' fees and other estimated offering expenses payable by Clarus, are expected to be approximately $15M. Clarus intends to use the net proceeds from the private placement to support growth initiatives for its near-term commercial objectives for its oral testosterone replacement product, JATENZO. Pursuant to the terms of the securities purchase agreement, Clarus will issue to the investor 3,024,194 units at a price of $4.96 per unit. Each unit consists of one share of common stock and a warrant to purchase one share of common stock at an exercise price of $5.25 per share. The warrants will become exercisable six months following the closing and have a five-year term. The private placement is expected to close on or about December 7, 2021, subject to the satisfaction of customary closing conditions.
SISI

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09:05 EST Shineco to acquire controlling interest in Xiang Peng You Kang Technology - Shineco announced that on November 18, 2021, it entered into non-binding framework agreements with certain shareholders of Xiang Peng You Kang Technology, a comprehensive medical and healthcare company, to acquire at least 51% equity interest of XPYK, intending to develop an integrated medical and health services system of the Company. The final purchase price will be separately determined based on the evaluation report issued by a third party. The Company expects to develop comprehensive medical and healthcare services through upgrading XPYK's Yikang International Medical and Health Service platform and accelerating its digital transformation. XPYK is a comprehensive medical and healthcare group that develops biotechnology and integrates medical services and health management. As the core of XPYK's business, the Platform has industry-leading medical and healthcare resources and an integrated service system, providing patients with online and offline medical and healthcare service solutions including convenient medical services and health management services. For convenient medical services, the major services are pre-diagnosis consultation and triage advice, assistance in medical consultation, in-diagnosis guidance, post-diagnosis rehabilitation, health tracking, and domestic and international medical consultations. For health management services, the major services are private family doctors, 24/7 telephone doctor service, physical examination management, on-site care, and healthcare report interpretation. Completion of the transaction is subject to due diligence investigations by the relevant parties, the negotiation and execution of a definitive share purchase agreement, satisfaction of the conditions negotiated therein including the approval of the Company's Board of Directors, and the satisfaction of other customary closing conditions. There can be no assurance that a definitive agreement will be entered into or that the proposed transaction will be consummated. Further, readers are cautioned that the terms of the Framework Agreements contained herein describing the proposed transaction are non-binding.
GOVX

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09:03 EST GeoVax Labs presents hemorrhagic fever data at World Vaccine Congress - GeoVax Labs presented data from ongoing studies of its investigational vaccines against hemorrhagic fevers at the recent World Vaccine & Immunotherapy Congress, held November 30 - December 2 in San Diego, California. The presentation, titled "Design and Evaluation of Vaccines Against Hemorrhagic Fevers using the MVA-VLP Platform", was delivered by Mary Hauser, PhD, GeoVax Senior Scientist. In her talk, Dr. Hauser discussed the preclinical efficacy of GeoVax's vaccines against Sudan and Marburg (MARV) viruses, two highly virulent filovirus strains that cause hemorrhagic fever. Recent studies in lethal challenge guinea pig models demonstrated that GeoVax vaccines MVA-VLP-SUDV and MVA-VLP-MARV conferred 100% protection from death. These vaccines were subsequently evaluated in a rigorous cynomolgus macaque infectious challenge model. Vaccination protected nonhuman primates from viremia, weight loss and death following challenge with a dose of Sudan or Marburg virus that is lethal in nonvaccinated animals. Evaluation of immune responses following vaccination demonstrated presence of both neutralizing antibodies and functional T cells, indicating a breadth of responses that combine for optimal protection. Mark Newman, PhD, GeoVax Chief Scientific Officer, commented, "The ability of vaccines based on the GV-MVA-VLP platform to induce protective immunity from such deadly pathogens is impressive. We believe these results support further development efforts with our partners and collaborators towards clinical evaluation to document safety and immunogenicity in humans."
SRGA

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09:03 EST Surgalign reports inducement grants under Nasdaq listing rule - Surgalign Holdings announced that it has granted restricted stock unit awards to three employees, none of whom are executive officers, as an inducement for them to accept employment with Surgalign, and representing the right to receive, in the aggregate, up to 24,000 shares of Surgalign common stock. The awards were granted on December 1, 2021 under the Surgalign Holdings, Inc. 2021 Inducement Plan. One-third of the restricted stock units vest on the first anniversary of the date of grant, and one-eighth of the remaining restricted stock units vest on each subsequent quarterly anniversary of the date of grant, such that the award will be fully vested on the third anniversary of the date of grant, subject to continued employment through the applicable vesting date. The awards were approved by the independent Compensation Committee of the Board of Directors of Surgalign Holdings and were granted to the new employees as an inducement material to their acceptance of employment with Surgalign pursuant to Nasdaq rules.
ECPG

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09:02 EST Encore Capital announces preliminary results of tender offer - Encore Capital Group announced the preliminary results of its modified "Dutch auction" tender offer to purchase with cash up to $300M of shares of its common stock which expired one minute after 11:59 P.M. on December 2, 2021. Based on the preliminary count by the depositary for the tender offer, a total of 4,474,814 shares of common stock were validly tendered and not validly withdrawn at or below the price of $60.00 per share, including 641,340 shares that were tendered through notice of guaranteed delivery. In accordance with the terms and conditions of the tender offer and based on the preliminary count by the depositary, the Company expects to purchase a total of 4,474,814 shares of common stock through the tender offer at a price of $60.00 per share, for a total cost of $268,488,840, excluding fees and expenses. The total of 4,474,814 shares of common stock that the Company expects to accept for purchase represents approximately 15% of the Company's total shares of common stock outstanding as of October 28, 2021.
SCVL

Hot Stocks

08:49 EST Shoe Carnival acquires Shoe Station, sees accretion - Shoe Carnival announced that it has acquired substantially all of the assets of privately-held, family-owned Shoe Station, which operates stores in five Southeastern states. The Shoe Station assets were acquired for $67M, subject to customary adjustments, funded through cash on hand. The transaction is expected to be immediately accretive to diluted net income per share in FY22, contributing approximately $100M in incremental net sales, with operating income exceeding 10% on a normalized basis. After the close of this acquisition, the company will have more than $100M in cash on hand, consistent with cash reserves from the same period in FY20. With the addition of Shoe Station to the Shoe Carnival portfolio, the company expects to surpass 400 stores by the end of 2022, on a path to double-digit new store growth in the years ahead.
SCYX

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08:44 EST Scynexis reports exercise of warrants totalling $7.9M - SCYNEXIS reported the exercise of warrants to purchase 1.2M shares of SCYNEXIS common stock by Federated Hermes Kaufmann Small Cap Fund and Dafna Lifescience LP for which SCYNEXIS accepted a reduced exercise price. Proceeds to SCYNEXIS are approximately $7.9M. The exercised warrants were issued in SCYNEXIS's December 2019 financing. The remaining warrants issued in the December 2019 financing covering approximately 3.2M shares of common stock expired unexercised on December 2, 2021.
ZG

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08:43 EST Zillow Group announces up to $750M share repurchase plan - Zillow Group announced it has made significant progress in winding down Zillow Offers inventory and has sold, is under contract to sell or has reached agreement on disposition terms for more than 50% of the homes it expected to resell during the entire wind-down process. Zillow Group's board of directors has also authorized the repurchase of up to $750M of its Class A common stock, Class C capital stock or a combination of both.
FSP

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08:35 EST Franklin Street declares 32c per share special dividend - Franklin Street announced that its board of directors declared a special cash dividend of 32c per share of common stock payable on January 12, 2022 to stockholders of record as of the close of business on December 31. The decision to declare a special dividend was a result of taxable gains realized on our previously disclosed dispositions of approximately $600M of assets in the aggregate during 2021.
BYRN

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08:34 EST Byrna Technologies: Spokane PD approves weapons purchases - Byrna Technologies announced that on Tuesday, November 30th, the Spokane County Board of County Commissioners voted to approve the purchase of several types of Byrna Less-Lethal launchers, including 200 of the newest addition to the Byrna line, the Tactical Compact Rifle, along with 39,000 rounds of Byrna non-lethal ammunition and accessories. These launchers will be provided to the Spokane County Sheriff's Office patrol division, SWAT Team, and their TAC Unit which is charged with managing instances of civil disorder. It is the intent of the Sheriff's office to place one of the 200 TCR's in every patrol car, giving ALL the Spokane Deputies the ability to deploy a Byrna launcher at a moment's notice.
CASY ODP

Hot Stocks

08:34 EST Casey's General Stores appoints Katrina Lindsey chief legal officer - Casey's General Stores (CASY) announced that Katrina Lindsey is joining the company as chief legal officer and corporate secretary. This role leads Casey's legal, risk management, compliance, food safety, government affairs and corporate reporting functions at the third largest convenience retailer and fifth largest pizza chain in the U.S. Lindsey will report to CEO Darren Rebelez and start in January. Lindsey's experience most recently includes several years at Office Depot (ODP) where she served as senior VP, deputy general counsel, chief compliance officer and assistant corporate secretary.
HCDI

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08:33 EST Harbor Custom Development to acquire 997-unit planned community for $14M - Harbor Custom Development announced that it has entered into a contract to acquire Grandis Pond, a 438-acre master-planned community in Blaine, Washington on the Washington/Canadian border for $14,000,000. "Grandis Pond is the largest project Harbor has contracted for purchase to date and will nearly double the Company's current inventory by adding a mix of residential housing with up to 997 single and multi-family housing units and approximately 48,000 square feet of neighborhood commercial space," the company said. Harbor Custom Development's President and CEO, Sterling Griffin said, "We are pleased to announce the Company has entered into a contract to complete the Grandis Pond master plan. This project will help alleviate the residential inventory shortage in Blaine and Whatcom County, Washington, and Vancouver, British Columbia, and will significantly increase our position in these growing markets. The multiyear project is a major step forward for the Company as it allows us to meet our short and long term revenue objectives, offers multiple product types and provides for the opportunity to monetize sections of the masterplan early in the development cycle."
RVVTF

Hot Stocks

08:32 EST Revive Therapeutics expands bucillamine research to treat omicron variant - Revive Therapeutics is pleased to announce that the Company has decided to expand research with Bucillamine, an oral drug shown to have promising anti-viral and anti-inflammatory capabilities and is being evaluated in a current Phase 3 clinical study for COVID-19, as a potential treatment for the Omicron variant. The expansion to explore Bucillamine's therapeutic potential for the Omicron variant is supported from a recent research study published, titled "Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE2 in vitro" from the University of California, San Francisco, which revealed that potent thiol drugs, like Bucillamine, inhibit SARS-CoV-2 infection in vitro, specifically the Delta variant and also reduces SARS-CoV-2-related lung injury in vivo and provides a strong rationale for trials of systemically delivered thiol drugs as COVID-19 treatments. In addition, thiol-based drugs, like Bucillamine, have been shown in research models to decrease the binding of SARS-CoV-2 spike protein to its receptor, decrease the entry efficiency of SARS-CoV-2 spike pseudotyped virus, and inhibit SARS-CoV-2 live virus infection. The Company supported recent research to explore the utility of thiol-based drugs under its sponsored research agreement with the University of California, San Francisco in the laboratory of Dr. John Fahy. In a study that evaluated the role of pro-inflammatory cytokines that are highly upregulated in patients with COVID-19 in inducing inflammatory cell death, inflammation, tissue and organ damage, and mortality showed that the specific combination of tumor necrosis factor alpha and interferon gamma is critical for these processes. Furthermore, it was found that inhibiting TNF-alpha and IFN-gamma protected against death in SARS-CoV-2 infection and models of sepsis, hemophagocytic lymphohistiocytosis, and cytokine shock, suggesting that this pathway can be applicable beyond COVID-19 in infectious and inflammatory diseases where TNF-alpha and IFN-gamma-mediated inflammatory cell death drive the pathology. There is evidence that Bucillamine inhibits pro-inflammatory cytokine production and transendothelial T-cell migration, both of which could further dampen disease course in COVID-19. As a result of the research and the rise of the Delta variant and Omicron variant, the Company has decided that in addition to incorporating viral load testing, it will also be adding inflammatory markers to complement the ongoing Phase 3 clinical trial evaluating the safety and efficacy of Bucillamine in patients with mild to moderate COVID-19. These inflammatory markers will allow the Company to understand Bucillamine's potential as an anti-inflammatory agent in the treatment course and provide confidence in the potential utility and effectiveness of Bucillamine in COVID-19.
MULN

Hot Stocks

08:31 EST Mullen Automotive begins validation process for Class 2 EV cargo vans - Mullen Automotive announces that initial validation testing of the Class 2 EV cargo van has begun at Mullen's Advanced Manufacturing and Engineering Center, AMEC, in Tunica, Mississippi. Mullen's Class 2 EV cargo van is based on a 144-inch wheelbase, 78.8-kWh battery pack, rear-wheel drive and modular 460-cubic-foot cargo area. Vehicle range is estimated at over 200 miles, with a max payload of 3,296 pounds. The Class 2 EV vans are equipped with modular cargo areas that can be easily adapted to different client configurations. Mullen is currently on track to deliver initial vans to existing fleet order customers starting in Q2 2022. "Our Class 2 EV cargo van initial validation testing has begun at our AMEC facility in Tunica," said David Michery, CEO and chairman of Mullen Automotive. "The Mullen One is our first major manufacturing program out of our Tunica facility, and the entire team in California and Mississippi is excited to be working on the EV Cargo Van program."
SABR AXP

Hot Stocks

08:31 EST Sabre, American Express Global Business Travel announce partnership - Sabre (SABR) and American Express (AXP) Global Business Travel announce a long-term, multi-faceted strategic partnership focused on developing technologies that will enable the future of corporate travel distribution. Under the terms of this newly expanded technology partnership - which takes effect in January 2022 - GBT will increase its commitment with Sabre and make a multi-million dollar, long-term annual investment in joint technology development with Sabre over the next ten years. The partnership between two industry leaders puts the two companies in an ideal position to deliver best-in-class products and services throughout the corporate travel ecosystem and drive meaningful growth to both companies and the travel ecosystem in its entirety.
CGRN

Hot Stocks

08:26 EST Capstone Green Energy distributor signs new 10-year FPP, CHP - Capstone Green Energy announced that its Distributor in Austria and Germany, Wels Strom has been contracted by IFG Asota to provide a combined heat and power, or CHP, system plus a 10-year Factory Protection Plan for their fiber manufacturing plant in Linz, Austria.
EHC

Hot Stocks

08:12 EST Encompass Health to build inpatient rehabilitation hospital in Amarillo, Texas - Encompass Health announced plans to build a freestanding, 40-bed inpatient rehabilitation hospital in Amarillo, Texas. The hospital will be located north of the Wallace Boulevard and Gentry Drive intersection. The construction start date and hospital opening timeline will be announced at a later date.
RCII

Hot Stocks

08:10 EST Rent-A-Center announces $500M share repurchase authorization - Rent-A-Center announced that its board of directors has approved a new share repurchase authorization of up to $500M of the company's common stock, following the recent completion of the $250M share repurchase authorization the company announced in August. Share repurchases may be made in the open market, through 10b5-1 programs, through privately negotiated transactions or otherwise. The company is not obligated to acquire any shares, and the board of directors may modify, extend or terminate share repurchases any time. The board of directors also approved an increase of approximately 10% in the quarterly cash dividend to 34c for the first quarter of 2022. The dividend will be paid on January 13, 2022 to the company's common stockholders of record as of the close of business on December 16.
IMAB

Hot Stocks

08:08 EST I-Mab says first two patients dosed in Phase 2 uliledlimab/atezolizumab trial - I-Mab announced that the first two patients have been dosed in the U.S. phase 2 dose expansion clinical study of its proprietary CD73 antibody uliledlimab in combination with atezolizumab in patients with ovarian cancer and other selected advanced or metastatic solid tumors.
FVE

Hot Stocks

08:07 EST Five Star Senior Living announces collaboration with Compass Community Living - Five Star Senior Living announced a collaboration with Compass Community Living, a division of Compass Group, a leader in food and support services, whereby Compass will assume management of dining services operations at all of Five Star's senior living communities. The collaboration advances Five Star's commitment to delivering differentiated, customer-focused experiences. The transition of Five Star's dining services operations will begin on February 1, 2022 and is expected to be completed by year end 2022. As part of the transition, it is expected that Five Star employees currently working in dining services will become employees of Compass Community Living.
MARA...

Hot Stocks

08:06 EST Marathon Digital Bitcoin publishes bitcoin production updates for November - Marathon Digital (MARA) published unaudited bitcoin (BTC) production and miner installation updates for November 2021. Maintenance and upgrades to the power generating facility in Hardin, MT negatively impacted bitcoin production for a portion of November, resulting in 196 self-mined bitcoin during November 2021. As of December 1, 2021, Marathon's mining fleet has produced approximately 2,712.3 self-mined bitcoin during 2021. Cash on hand was approximately $623.7M and total liquidity, defined as cash and bitcoin holdings, was approximately $1.1B. The company received approximately 15,520 top-tier ASIC miners from Bitmain during the month of November and 56,826 miners year to date with an additional 8,477 miners currently in transit. Marathon fully completed miner installations at the Company's facility in Hardin, MT, as well as scheduled upgrades and maintenance to the power generating facility in Hardin, MT. Following successful system upgrades to the power plant in Hardin, MT, produced approximately 34 bitcoin on December 1, 2021, as the power plant and Marathon's miners in Hardin began operating near full capacity. Increased total bitcoin holdings to approximately 7,649.1 with a fair market value of approximately $437.4M. Existing mining fleet consists of 31,000 active miners producing approximately 3.2 EH/s
AMSF

Hot Stocks

08:06 EST Amerisafe announces planned retirement of CFO Neal Fuller - Amerisafe announced Neal Fuller, its CFO, plans to retire. Fuller informed the company that he currently expects to retire in 2022 and that he will remain with the company to assist in the transition of his responsibilities to his successor. Fuller joined Amerisafe in September 2015 as executive VP and CFO, and has over 30 years of experience in leadership within the insurance industry.
SHCR

Hot Stocks

08:05 EST Sharecare's Unwinding Anxiety shown to decrease anxiety by 67% in trial - Prior to COVID-19, research showed more than 1 in 4 American adults will experience at least one anxiety disorder in their lifetime, costing the U.S. healthcare system an estimated $42.3B-$46.6B annually. Meanwhile, in 2020, anxiety, stress, and worry increased by nearly three-fold in the U.S., leading to a significant increase in demand for treatments, in particular telehealth and digital therapeutics due to limitations on in-office appointments. According to new research published in the Journal of Medical Internet Research, Unwinding Anxiety, an evidence-based digital therapeutic from Sharecare, decreased anxiety in participants by 67% after two months of use. The randomized controlled trial was funded by a grant from the National Institute of Mental Health and led by renowned neuroscientist and addiction psychiatrist Dr. Jud Brewer, an associate professor of Behavioral and Social Sciences in the Brown University School of Public Health, and his team of researchers. Participants in the study were randomized during an in-person visit where half were assigned to continue with their current treatment plans and the other half added the Unwinding Anxiety app. At two months, the control group saw a 14% reduction in anxiety compared to a 67% reduction seen in the group assigned to use Unwinding Anxiety.
OXLC

Hot Stocks

08:03 EST Oxford Lane estimates November NAV $6.84-$6.94 - Oxford Lane Capital announced the following net asset value estimate as of November 30, 2021. Management's unaudited estimate of the range of the NAV per share of our common stock as of November 30, 2021 is between $6.84 and $6.94. This estimate is not a comprehensive statement of our financial condition or results for the month ended November 30, 2021. This estimate did not undergo the Company's typical quarter-end financial closing procedures and was not approved by the Company's board of directors. We advise you that our NAV per share for the quarter ending December 31, 2021 may differ materially from this estimate, which is given only as of November 30, 2021. As of November 30, 2021, the Company had approximately 122.8 million shares of common stock issued and outstanding.
CMMB

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08:02 EST Chemomab Therapeutics names David Weiner, MD as Interim Chief Medical Officer - Chemomab Therapeutics announced that David Weiner, MD has been named Interim Chief Medical Officer, effective immediately. This position will be in a part-time capacity. Dr. Weiner is replacing Dr. Arnon Aharon, who has resigned. Dr. Aharon intends to continue at Chemomab for the next 60 days and as a senior medical advisor thereafter to ensure a seamless transition. Weiner, who is based in the U.S., has more than 25 years of experience in the discovery and clinical development of novel therapeutics and has held senior executive roles at private and public biotechnology companies.
CG

Hot Stocks

08:01 EST GTCR announces strategic investment in Resonetics by Carlyle - GTCR, a private equity firm, announced that its portfolio company, Resonetics, has sold a minority equity stake to funds affiliated with global investment firm Carlyle, valuing the company at approximately $2.25B. Carlyle will join GTCR as a meaningful shareholder in Resonetics as a result of the transaction.
IESC

Hot Stocks

07:55 EST IES Holdings appoints Matthew Simmes as COO - ES Holdings announced the appointment of Matthew Simmes as COO of the Company. In his new role, Mr. Simmes, who has been President of the Company's Communications segment since 2017, will oversee all four of the Company's operating segments.
LXXGF

Hot Stocks

07:51 EST Lexagene Holdings closes multiple MiQLab sales - LexaGene Holdings is pleased to announce two purchase orders from Kuma Veterinary Clinic and the Emergency Veterinary Services of Roanoke.
RHHBY

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07:34 EST Roche says developed added testing options to differentiate mutations in omicron - Roche and TIB Molbiol, a newly acquired subsidiary within the Roche Diagnostics division, have added three additional Research Use Only, or RUO, test kits for the detection of mutations present in the novel B.1.1.529 Omicron SARS-CoV-2 variant: VirSNip SARS Spike ins214EPE, VirSNiP SARS-CoV-2 Spike S371L S373P, and VirSNip SARS Spike E484A, the company announced. "The COVID-19 pandemic continues to be an evolving and complex situation, and Roche is committed to responding to healthcare's biggest challenges. The teams at TIB Molbiol have worked around the clock since the new variant emerged, and today we are able to offer a test that can specifically identify the novel B.1.1.529 Omicron SARS-CoV-2 variant to help better understand its spread and behaviour. There is still much to learn about Omicron. It's critical to identify Omicron quickly and accurately, which will help inform ongoing research - including the further development of therapeutics and vaccines - and potentially stop or slow down the advance of this new variant," said Thomas Schinecker, CEO Roche Diagnostics.
BHP

Hot Stocks

07:33 EST BHP Group extends tender expiry, outside date under Noront support agreement - BHP Lonsdale Investments that it is progressing discussions with Wyloo Metals regarding Wyloo Metals' potential support of BHP's C$0.75 per share offer to acquire Noront Resources. To allow more time for those discussions to progress, BHP is extending the expiry of its offer from 7:00 p.m. on December 14, 2021 to 7:00 p.m. on January 14, 2022. The earliest time BHP will acquire Noront shares under its Offer will be at the new expiry time. In conjunction with the extension of the expiry time, BHP Lonsdale and Noront also announced that they have amended the Support Agreement, dated July 26, 2021 and previously amended on October 19, 2021, between BHP Lonsdale, its subsidiary BHP Western Mining Resources International and Noront relating to Noront's support of the Offer in order to extend the outside date in that agreement from December 14, 2021 to January 21, 2022. The Outside Date is relevant because, among other things, if the Offeror has not acquired shares under the Offer by the Outside Date, both Noront and the Offeror become permitted to terminate the Support Agreement. While BHP and Wyloo Metals are considering a mutually beneficial arrangement regarding the acquisition of Noront by BHP, there is no assurance that any agreement will be reached between BHP and Wyloo Metals.
DGLY

Hot Stocks

07:32 EST Digital Ally announces notable order for body-worn cameras in New Jersey - Digital Ally announces it has received an upgrade order from the Carteret Police Department, New Jersey for 180 FirstVu HD body cameras and docking stations. Carteret PD, a legacy customer of Digital Ally since 2008, purchased this equipment with the help of the State of New Jersey Body-Worn Camera Grant Program. "We are very excited to continue our long-standing relationship with the Carteret Police Department," said Stan Ross, CEO of Digital Ally, adding, "As the body camera industry continues to evolve, Digital Ally remains committed to providing all departments the ability to equip their officers with the latest technology."
IP

Hot Stocks

07:32 EST International Paper says GHG reduction target approved by SBTi - The company stated, "International Paper announced our 35% Greenhouse Gas reduction target has been approved by Science Based Targets initiative as consistent with levels required to meet the goals of the Paris Agreement. The targets covering greenhouse gas emissions from International Paper's operations are consistent with reductions required to keep warming to well-below 2 degrees C. Additionally, International Paper's target for the emissions from its value chain meet the SBTi's criteria for ambitious value chain goals, meaning they are in line with current best practice."
ZLAB

Hot Stocks

07:32 EST Zai Lab announces inclusion of ZEJULA in China's NRDL for ovarian cancer - Zai Lab announced that the National Reimbursement Drug List, NRDL, released by China's National Healthcare Security Administration, NHSA, has been updated to include ZEJULA as a first-line maintenance treatment of adult patients with advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer following a response to platinum-based chemotherapy, regardless of biomarker status. "A key part of Zai Lab's mission is to bring transformative medicines to patients in China," said Dr. Samantha Du, Founder, Chairperson, and Chief Executive Officer of Zai Lab. "The inclusion of ZEJULA in the NRDL for first-line maintenance treatment of ovarian cancer is an important step in achieving that mission. We are grateful for this action by the NHSA to make ZEJULA more accessible to Chinese patients with ovarian cancer."
HGTY ADF

Hot Stocks

07:17 EST Hagerty to begin trading on NYSE on December 3 - Hagerty (HGTY) announced that shares of its common stock and warrants will begin trading December 3 on the New York Stock Exchange under the ticker symbols "HGTY" and "HGTY.WS," respectively. This follows the completion of the company's previously announced business combination with Aldel Financial (ADF). Aldel shareholders approved the business combination at a special meeting held on December 1. Hagerty executives will ring the bell to open the trading day at the New York Stock Exchange on Monday, December 6.
XENE

Hot Stocks

07:10 EST Xenon Pharmaceuticals presents additional data from Phase 2b X-TOLE trial - Xenon Pharmaceuticals announced that additional positive data from new sub-analyses of the Phase 2b X-TOLE clinical trial will be presented in a scientific poster entitled "Phase 2b Efficacy and Safety of XEN1101, a Novel Potassium Channel Modulator, In Adults With Focal Epilepsy" and at a Xenon-sponsored scientific symposium at the Annual Meeting of the American Epilepsy Society, AES 2021. On October 4, 2021, Xenon announced that the X-TOLE trial had met its primary efficacy endpoint with XEN1101 demonstrating a statistically significant and dose-dependent reduction from baseline in monthly. In addition to the topline data, additional sub-analyses have been completed and are being presented at AES 2021. These new analyses include the proportion of patients with at least a 75% reduction in monthly focal seizure frequency from baseline along with the proportion of patients who achieved 100% reduction in monthly seizure frequency from baseline. Additional sub-analyses were performed in patients with different baseline characteristics given that X-TOLE included a "difficult-to-treat" patient population as defined by the number of prior failed anti-seizure medications, concomitant ASMs on study, and baseline seizure burden. Highlights of X-TOLE Efficacy Results: The monotonic dose response relationship between the XEN1101 active dose groups compared to placebo was statistically significant; XEN1101 demonstrated a statistically significant reduction from baseline in monthly focal seizure frequency in pairwise comparisons to placebo for all three XEN1101 doses; a pre-specified secondary endpoint of the study was a responder analysis, which compared the proportion of study subjects treated with XEN1101 who achieved a greater than or equal to 50% reduction in monthly focal seizures versus placebo; and these marked reductions in seizures were associated with statistically significant improvements in overall status. The XEN1101 25 mg group was statistically significant in CGI-C and PGI-C, and the XEN1101 20 mg group was statistically significant in PGI-C, while the XEN1101 20 mg group in CGI-C and the XEN1101 10 mg group for both CGI-C and PGI-C showed numerical improvements over placebo but were not statistically significant. Highlights of X-TOLE Safety Results: XEN1101 was generally well-tolerated in this study with adverse events consistent with other ASMs. The incidence of treatment-emergent adverse events was higher in the treatment groups as compared to the placebo group; TEAEs greater than or equal to 5% in all treatment arms were attributed to nervous system disorders; The incidence of treatment-emergent serious adverse events was similar in all four arms of the study; there were 3.5% of subjects in the placebo group, 2.2% of subjects in the XEN1101 10 mg group, 13.7% of subjects in the XEN1101 20 mg group, and 15.8% of subjects in the XEN1101 25 mg group that had an AE leading to treatment discontinuation
ACRS

Hot Stocks

07:06 EST Aclaris Therapeutics publishes preclinical research on zunsemetinib - Aclaris Therapeutics announced the publication of preclinical research of zunsemetinib in pancreatic cancer in the peer-reviewed journal Science Translational Medicine, on December 1, 2021. The article, entitled "The MK2/Hsp27 axis is a major survival mechanism for pancreatic ductal adenocarcinoma under genotoxic stress," presents the results from a preclinical study using patient-derived cell lines and an autochthonous pancreatic ductal adenocarcinoma mouse model that evaluated the role of MK2, as well as the impact of zunsemetinib, Aclaris' investigational oral MK2 inhibitor, in pancreatic cancer. This study was a multi-year collaboration between Aclaris and Washington University School of Medicine, led by the laboratory of Dr. Kian-Huat Lim, MD, PhD, Associate Professor in Oncology and Dr. Patrick Grierson, MD, PhD, Assistant Professor in Oncology. In the study, Dr. Lim and his team identified the MK2/HSP27 axis as an important resistance mechanism resulting in pancreatic tumor cell survival following exposure to components of FOLFIRINOX chemotherapy - the current standard-of-care treatment for pancreatic cancer. His team also demonstrated that DNA damage induced by FOLFIRINOX chemotherapy components upregulated tumor necrosis factor alpha in pancreatic cancer cells, which had the dual effect of impacting cell death and cell survival, and that the selective inhibition of MK2 downstream of TNFa signaling abrogated survival through blocking HSP27 activation and beclin1 mediated autophagy, which allowed TNFa to execute its pro-death mechanism. With this understanding, his team then showed that mouse survival in an autochthonous KPPC model of pancreatic cancer was statistically significantly extended when dosed with zunsemetinib in combination with FIRINOX. Based on these results and clinical data generated from Aclaris' clinical development program with zunsemetinib, Aclaris is considering a future clinical program for the treatment of patients with pancreatic cancer using one of Aclaris' other MK2 inhibitor drug candidates.
LMB

Hot Stocks

07:05 EST Limbach Holding acquires Jake Marshall for $20M in cash - Limbach Holding announced the closing of the acquisition of Chattanooga, Tennessee-based specialty mechanical contractor Jake Marshall, along with certain affiliated companies, for an enterprise value of $20M in an all-cash transaction. From 2014-2020, Jake Marshall generated on average more than $45M in revenue and $4.5M in EBITDA annually. Net consideration paid by Limbach at closing was $20M, which was sourced from available cash in the amount of $10M and additional term loan borrowings of $10M provided by the company's lenders. Additionally, Jake Marshall's owners may receive up to $6M in total future cash consideration subject to meeting certain performance thresholders in calendar years 2022 and 2023.
FOLD

Hot Stocks

07:04 EST Amicus announces EMA validated MAA for AT-GAA - Amicus Therapeutics announced that the European Medicines Agency, EMA, validated the Marketing Authorization Applications, MAA, for AT-GAA, the Company's investigational two-component therapy for the treatment of Pompe disease. Validation of the application confirms the submission is accepted, and the EMA's centralized procedure with Committee for Medicinal Products for Human Use's, CHMP, assessment begins. The MAAs were submitted to the EMA based on the evaluation of the effects of AT-GAA in adults living with Pompe disease and its safety profile, which include data from the Phase 1/2 and Phase 3 PROPEL studies, as well as data from the long-term open-label extension study. John Crowley, Chairman and Chief Executive Officer of Amicus Therapeutics, stated, "The acceptance of these filings is an important step forward for people living with Pompe disease and their families in Europe. Patients need new medicines as soon as possible. We will work with great urgency with the EMA as they review the applications over the course of the coming months. With today's announcement, we remain confident in the potential of this medicine to become the next standard of care in Pompe disease."
BCRX

Hot Stocks

07:04 EST BioCryst reports inducement grants under Nasdaq listing rule - BioCryst Pharmaceuticals announced that the compensation committee of BioCryst's board of directors granted 11 newly-hired employees inducement options to purchase an aggregate of 84,000 shares of BioCryst common stock on November 30, 2021 as inducements material to each employee entering into employment with BioCryst. The options were granted in accordance with Nasdaq Listing Rule 5635(c)(4). The options have an exercise price of $12.06 per share, which is equal to the closing price of BioCryst common stock on the grant date. The options vest in four equal annual installments beginning on the one-year anniversary of the grant date, in each case subject to the new employee's continued service with the company. Each stock option has a 10-year term and is subject to the terms and conditions of BioCryst's Inducement Equity Incentive Plan and a stock option agreement covering the grant.
CMPS KPTI

Hot Stocks

07:03 EST Compass Pathways appoints Michael Falvey as Chief Financial Officer - COMPASS Pathways (CMPS) announced that it has appointed Michael Falvey as Chief Financial Officer, replacing Piers Morgan when he leaves the company, as previously announced, at the end of the year. Michael Falvey joins COMPASS most recently from Karyopharm Therapeutics (KPTI), where he led the financial strategy and prepared the financial infrastructure to support commercial operations. Falvey will assume the title of Chief Financial Officer on 1 January 2022.
ENOB

Hot Stocks

07:02 EST Enochian Biosciences presents human, lab data on treating solid tumors - Enochian BioSciences announced that Dr. Serhat Gumrukcu, Inventor and Co-Founder of Enochian BioSciences, and Founder and Director of Seraph Research Institute, presented new data and announced a partnership between Enochian and Dr. Anahid Jewett, a leader in tumor immunology and cell and gene therapy, on pancreatic cancer, as well as a combined effort with SRI and Enochian on Glioblastoma. For the first time, Dr. Gumrukcu revealed the proprietary genetic modifications of allogeneic dendritic cells that are the basis of Enochian's oncology pipeline, and laboratory studies showing a strong response across key parts of the immune system. He also provided an update on a published case report of a patient with recurrent glioblastoma who had a remaining tumor after surgery to remove it, which carries a very poor prognosis. The patient was treated with non-genetically-modified allogeneic DC loaded with an antigen known to be part of many glioblastomas and allogeneic Natural Killer cells. At the time of the report, the patient was tumor free for 15 months. He is now 2 years without evidence of the cancer recurring. The laboratory data presented suggest the Enochian pipeline products could be even more effective.
BMY MRK

Hot Stocks

07:00 EST Bristol-Myers: FDA accepts for priority review sBLA for Reblozyl - Bristol Myers Squibb (BMY) announced that the U.S. FDA has accepted for priority review the supplemental Biologics License Application for Reblozyl, a first-in-class erythroid maturation agent, for the treatment of anemia in adults with non-transfusion dependent beta thalassemia. The FDA has set a Prescription Drug User Fee Act goal date of March 27, 2022. In addition, the European Medicines Agency has validated the Type II variation for Reblozyl in NTD beta thalassemia. Reblozyl is being co-developed and co-commercialized with Merck & Co. (MRK) following Merck's recent acquisition of Acceleron Pharma. These applications were based on safety and efficacy results from the pivotal Phase 2 BEYOND study evaluating Reblozyl plus best supportive care in patients with NTD beta thalassemia.
ACM

Hot Stocks

06:56 EST Aecom secures places on two Crown Commercial Service frameworks - Aecom announced it has secured places on two Crown Commercial Service frameworks, expanding its offering to government departments and public sector clients in the UK, and further enhancing its presence across the Crown Commercial Service as a Supplier Alliance Member. Aecom has secured five lots on the Crown Commercial Service's GBP1.7B Construction Professional Services Framework and has also secured a position on four lots of the major Crown Commercial Service Management Consultancy Framework. These frameworks will run for four years.
TT

Hot Stocks

06:46 EST Trane intends to increase dividend 14% in 1Q22 - Trane Technologies announced it intends to increase its dividend by 14%, from 59c to 67c per share quarterly and from $2.36 to $2.68 per share annualized, in the first quarter of 2022, subject to Board approval at such time. "Our sustainability-focused strategy and strong execution enables us to maximize business reinvestment, while at the same time return substantial cash to shareholders," said Dave Regnery, CEO. "When combined with our dividend increase of 11% in the first quarter of 2021, the annual dividend is expected to be up 26% since the separation of our industrial businesses and the launch of Trane Technologies in March of 2020. This announcement reinforces our commitment to paying a competitive dividend that grows at or above the rate of earnings growth over time, and reflects continued confidence in our ability to generate strong cash flow."
POAHY

Hot Stocks

06:44 EST Porsche Ventures becomes shareholder in 1KOMMA5 - Porsche announced it is expanding its investment portfolio in the field of smart city technology: the Stuttgart-based sports car manufacturer's venture capital unit, Porsche Ventures, is to become a shareholder in 1KOMMA5. The company said, "The Hamburg-based start-up has set itself the goal of expanding the market for carbon-neutral energy and air-conditioning technology in private households in a sustainable and decentralised way, thereby accelerating the transition to low-carbon and carbon-neutral energy. The way 1KOMMA5 works is to acquire interests in leading electrical installation companies across Europe with a focus on renewable energies, supporting them with digitalisation efforts and the centralisation of administrative tasks as well as providing growth capital. At the same time, networking concepts are being developed to make installed devices available for the energy services of the future via proprietary applications and interfaces - for example, smart electricity tariffs and virtual power plant concepts...With this investment, Porsche is expanding its involvement in companies outside its core business and underlining its ambitions in the area of sustainability." Reference Link
TT

Hot Stocks

06:42 EST Trane names Dave Regnery as chair of the Board, effective January 1, 2022 - The Board of Directors of Trane Technologies has appointed CEO Dave Regnery as chair of the Board, effective January 1, 2022. Regnery succeeds Mike Lamach, who has served as executive chair through the CEO transition and plans to formally retire from the company on December 31, 2021 following a smooth and successful transition of leadership. As previously announced, Gary Forsee, retired chair and CEO of Sprint Nextel and former president of the University of Missouri System, will continue to serve as lead independent director.
HIBB

Hot Stocks

06:36 EST Hibbett Sports CEO says 'very well-positioned' for holidays - Mike Longo, President and CEO, stated, "Our business continued to experience positive momentum during the third quarter. Our focused strategy of providing a compelling assortment of highly coveted merchandise coupled with superior customer service and a best-in-class omni-channel platform led to increased traffic, a higher average ticket, and a greater number of items purchased per transaction. The revenue growth and strong profitability we have generated over the past two years provides us with a solid base to continue expanding our reach and will contribute to achieving our long-term goals." Longo continued, "Despite ongoing challenges in the supply chain, our inventory position improved significantly during the third quarter. We are very well-positioned for the holiday selling season and our vendor partners continue to recognize and appreciate our differentiated business model and our ability to provide an outstanding customer experience in underserved communities."
PCG

Hot Stocks

06:32 EST California regulator fines PG&E $125M for 2019 Kincade wildfire - The California Public Utilities Commission approved penalties and permanent disallowances against Pacific Gas and Electric Company yesterday for violations related to the ignition of the 2019 Kincade wildfire. Under a settlement with the CPUC's Safety and Enforcement Division, PG&E shareholders will pay a $40M penalty to California's General Fund and incur an $85M permanent disallowance for cost recovery for the removal of abandoned transmission facilities within its service territory, for a total of $125M. The Kincade wildfire ignited in October 2019 within PG&E's service territory and burned more than 77,000 acres and destroyed nearly 374 structures. SED's investigation into the Kincade wildfire and the involvement of PG&E's infrastructure found multiple violations of General Order 95, a CPUC regulation that sets safety factors and strength requirements in the design, construction, and maintenance of overhead electrical lines and communications facilities. The settlement addresses the violations through shareholder-funded permanent removal of multiple abandoned transmission facilities within PG&E's service territory. The settlement is formally referred to as an Administrative Consent Order. This new enforcement tool was created in November 2020, when the CPUC adopted an Enforcement Policy to better serve Californians through streamlined enforcement actions that can be taken by CPUC enforcement staff in lieu of issuing a Citation or seeking a formal Order Instituting Investigation. The addition of these tools to the CPUC's enforcement options in 2020 moved the CPUC's practices more in line with the enforcement practices of many other state and local enforcement agencies.
PTEN

Hot Stocks

06:13 EST Patterson-UTI reports an average of 106 drilling rigs operating in November - Patterson-UTI reported that for the month of November, the company had an average of 106 drilling rigs operating in the United States. For the two months ended November 30, the company had an average of 104 drilling rigs operating in the United States.
BMO

Hot Stocks

06:11 EST Bank of Montreal to repurchase up to 22.5M shares - "Looking ahead to 2022, we will continue to position BMO for growth with the ensuing economic recovery. We are making targeted investments in technology and talent to drive enhanced customer experiences and deliver market-leading advice to help them make real financial progress. Today we announced a 25% dividend increase and our intention to repurchase up to 22.5 million shares, reflecting the strength of our capital position and confidence in delivering sustained, long-term performance for our shareholders," concluded Mr. White.
BMO

Hot Stocks

06:11 EST Bank of Montreal increases quarterly dividend to C$1.33 per share - Concurrent with the release of results, BMO announced a Q1 dividend of C$1.33 per common share, an increase of C$0.27 or 25% from the prior quarter and the prior year. The quarterly dividend of C$1.33 per common share is equivalent to an annual dividend of C$5.32 per common share.
BGNE

Hot Stocks

05:37 EST BeiGene announces China NMPA approval for Sylvant - BeiGene announced that the China National Medical Products Administration, or NMPA, has approved Sylvant for the treatment of adult patients with multicentric Castleman disease, or MCD, who are human immunodeficiency virus, or HIV, negative and human herpes virus-8, or HHV-8, negative, also known as idiopathic MCD, or iMCD,. This disease is a rare, life-threatening, and debilitating condition of the lymph nodes and related tissues. Siltuximab is a monoclonal antibody approved in the United States, European Union, and other countries and regions around the world.
BGNE

Hot Stocks

05:35 EST BeiGene announces three medicines included in NDRL by China NHSA - BeiGene announced that three of its medicines have been added to the most recent National Reimbursement Drug List, or NRDL, in China by the National Healthcare Security Administration, or NHSA. BeiGene-discovered medicines in the updated NRDL include: anti-PD-1 antibody tislelizumab in three new indications, including in lung and liver cancers; BTK inhibitor Brukinsa in one new indication; and the initial listing for PARP inhibitor pamiparib. The changes to the NRDL will be effective on January 1, 2022.
HCM

Hot Stocks

05:34 EST Hutchmed announces China NRDL to include Elunate, Sulanda - Hutchmed announced that, following the 2021 negotiations with the China National Healthcare Security Administration, or NHSA, on January 1, 2022 the updated National Reimbursement Drug List, or NRDL, will continue to include Elunate and will now include Sulanda.
MOLN

Hot Stocks

05:31 EST Molecular Partners enters MP0533 research collaboration with University of Bern - Molecular Partners announced a research collaboration with University of Bern, to advance the development of the company's wholly owned acute myeloid leukemia, or AML, candidate, MP0533, into the clinic. MP0533 is a DARPin designed to engage CD3 on T cells and target AML cells by the tumor associated antigens CD33, CD123 and CD70. The collaboration aims to leverage Molecular Partners' proprietary DARPin technology and the University of Bern group's expertise in AML, and specifically in leukemic stem cells, a hard-to-target cancer progenitor cell population.
HIMX

Hot Stocks

05:29 EST Himax chairman Biing-Seng Wu to purchase up to $10M of ADSs - Himax announced that its chairman Biing-Seng Wu intends to use his personal funds to purchase up to approximately $10M of the company's American depositary shares, or ADSs, in the open market, subject to market conditions and other factors. As of September 30, Biing-Seng Wu beneficially owns approximately 21.4% of the total outstanding shares of the company.
MCO

Hot Stocks

05:27 EST Moody's acquires PassFort, agrees to acquire kompany - Moody's announced that it has acquired PassFort and entered into an agreement to acquire 360kompany, two European providers of onboarding and Know Your Customer, or KYC, technology solutions. PassFort is a U.K. SaaS-based workflow platform for identity verification, customer onboarding, and risk analysis. Its software delivers data from over 25 third-party providers and automates the collection, verification, and secure storage of customer and supplier due diligence documentation. The integration of PassFort's platform into Moody's suite of KYC and compliance offerings will create a more holistic workflow solution, allowing customers to incorporate Moody's data, including credit, cyber, ESG, and climate analytics, directly into their proprietary processes. kompany is a Vienna, Austria-based platform for audit-proof business verification and KYC, operating a network of primary source information on more than 115 million companies across 200 jurisdictions. kompany's API will enable Moody's customers to complete shareholder analysis and entity verification in real-time, as well as retrieve original company filings and documents to meet their regulatory demands. The acquisition of PassFort and planned acquisition of kompany follow Moody's recent investments in KYC capabilities. Moody's will integrate both companies into its KYC business within Moody's Analytics. The acquisition of kompany is expected to close in Q1 of 2022, subject to the satisfaction of customary closing conditions, including the expiration or termination of applicable regulatory waiting periods, and will be funded with a combination of cash and shares of Moody's Corporation common stock. The acquisition of PassFort was funded with cash. Neither is expected to have a material impact on Moody's 2021 financial results.